Clinical trials: Cost-Effectiveness
Dental Caries
Occlusal ART Restorations in Primary Molars Using 3 Different GIC
The aim of this study is to evaluate the survival rate and the cost-effectiveness of occlusal-ART restorations using three GIC brands (Fuji IX, GC Europe; Maxxion R, FGM; Vitro Molar, DFL) in primary molars.
- Trial name
- NCT02377297
- Testing
- Restoration with Fuji IX, Restoration with Vitro Molar, Restoration with Maxxion R
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Ulcerative Colitis, Crohn Disease
A Multicentered Prospective Cohort Study of Chinese IBD Patients
Inflammatory bowel disease(IBD), including ulcerative colitis (UC) and Crohn's disease (CD), is characterized by chronic and recurrent nonspecific intestinal inflammation with high disability rate.
- Trial name
- NCT05386290
- Testing
- Infliximab, Vedolizumab, Ustekinumab
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking Union Medical College Hospital
Posttraumatic Stress Disorder (PTSD), Depression
Stepped Enhancement of PTSD Services Using Primary Care (STEPS UP): A Randomized Effectiveness Trial
The overall objective of this study is to test the effectiveness of a systems-level approach to primary care recognition and management of PTSD and depression in the military health system.
- Trial name
- STEPS UP (NCT01492348)
- Testing
- STEPS UP, OUC
- Where
- 6 sites in United States
- Volunteers
- 666 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Infertility
Screening for Uterine Cavity Abnormalities in Women Scheduled for IVF
Evaluation of the endometrial cavity is an important step in the infertility work-up, particularly if assisted reproductive therapy is planned.
- Trial name
- NCT02598921
- Testing
- three dimensional ultrasound, Office hysteroscopy
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Heart Failure, Self Care
Effect and Cost Effectiveness of a Dyadic Empowerment-based Heart Failure Management Program for Self-care
Global population aging has drastically increased healthcare spending worldwide, with the greatest portion going to hospital and community health services.
- Conditions
- Heart Failure, Self Care, Empowerment, Transitional Care
- Trial name
- NCT05806606
- Testing
- Dyadic empowerment based heart failure management program, Dyadic education program
- Where
- Hong Kong
- Volunteers
- 232 people
- Sponsor
- The University of Hong Kong
Silent Stroke
The Effectiveness and Cost Effectiveness of Intelligent Assessment of Gait Disorder in Silent Cerebrovascular Disease
This is a multi-center, randomized, double-blind, parallel-controlled, prospective study to compare the effectiveness and cost-effectiveness of intelligent and doctor groups for gait disorder screening.
- Trial name
- ACCURATE-1 (NCT04457908)
- Testing
- intelligent assessment
- Volunteers
- 1,000 people
- Sponsor
- Shanghai Zhongshan Hospital
Breast Cancer
Cost-Effectiveness of Abdominal-based Autogenous Tissue vs Tissue Expander-Implant Reconstruction - A Feasibility Study
It is estimated that about 25% and 40% of health care expenditures in Canada and USA respectively are wasted because of inefficiencies and not practicing evidence-based medicine.
- Trial name
- NCT02438449
- Testing
- Breast Reconstruction Surgery
- Where
- Canada
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- McMaster University
Pulmonary Disease, Chronic Obstructive
(Cost-)Effectiveness Interdisciplinary Community-based COPD Management Program (INTERCOM)
There is growing evidence that COPD is a multi-organ system disease. Besides impaired lung function, skeletal muscle weakness and weight loss are important determinants of impaired exercise performance, decreased quality of life…
- Trial name
- NCT00840892
- Testing
- INTERdisciplinary COMmunity-based COPD management (INTERCOM)
- Where
- 2 sites in Netherlands
- Volunteers
- 199 people
- Sponsor
- Maastricht University Medical Center
Osteoarthritis
Comparison of Ways to Prepare Patients for Decisions About Joint Replacement Surgery
Ministries of Health consider wait lists for total joint replacement a top priority. Research priorities to manage wait lists indicate the need to establish benchmarks that consider patient preferences.
- Trial name
- NCT00911638
- Testing
- Patient decision aid, Usual care
- Where
- 2 sites in Canada
- Volunteers
- 343 people
- Sponsor
- Ottawa Hospital Research Institute
Hepatitis B Virus
Validity and Cost-Effectiveness of a New Screening Test for Hepatocellular Carcinoma
The purpose of this study is: 1. To establish and compare the diagnostic utilities for hepatocellular carcinoma (HCC) screening tests of (a) HS-AFP, (b) AFP + US,(c) AFP alone and (d) US alone (within HBV carriers between age 40…
- Trial name
- NCT00912847
- Volunteers
- 1,018 people
- Sponsor
- Chinese University of Hong Kong
Child Maltreatment
Effectiveness and Cost-effectiveness of Coaching Models to Promote Implementation of an Evidence-based Parenting Program
The proposed study will compare purveyor coaching (conducted by National SafeCare Training and Research Center (NSTRC)) to local coaching that is supported by the purveyor (NSTRC).
- Trial name
- NCT01791777
- Testing
- SafeCare Coaching
- Where
- 10 sites in United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Pediatric Femur Fracture
Pediatric Femur Fractures: Functional Bracing vs Spica Casting - Outcomes and Cost Analysis
Pediatric diaphyseal femur fractures that occur in children aged 6 months to 5 years old are traditionally treated with hip spica casting.
- Trial name
- NCT06569199
- Testing
- Functional Bracing, Hip Spica Cast
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- University of Calgary
Humeral Fracture
Proximal Humeral Comminuted Fractures in the Elderly - PERCELE Trial
Fractures of the proximal humerus are common in elderly patients. The optimal treatment of comminuted, displaced fractures is subject to controversy, and the results of operative treatment have not been shown to be superior to…
- Trial name
- NCT00999193
- Testing
- locking plate, ORIF, Hemiarthroplasty, Conservative treatment
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- University of Helsinki
Secondary School Entry and Completion, Education Advancement
Taabo Tutoring Study
Secondary school completion rates remain low in many low- and middle-income countries, including Côte d'Ivoire. Limited progression through lower secondary education may affect future educational and employment opportunities.
- Conditions
- Secondary School Entry and Completion, Education Advancement, School Attendance, Educational Attainment
- Trial name
- NCT07486778
- Testing
- Peer tutoring, Teacher tutoring
- Where
- Côte d’Ivoire
- Volunteers
- 1,000 people
- Sponsor
- San Diego State University
Menstrual Health Intervention, Product Use Issue
An MHH Intervention in Bangladesh Health Systems
Over 50% of Bangladeshi women and girls use old cloths as menstrual absorbents due to cost, comfort, and familiarity. A substantial proportion, comprising 52% of adolescent girls and 62% of women washed the cloths with soap and…
- Conditions
- Menstrual Health Intervention, Product Use Issue, Hygiene Practices and Knowledge, Menstrual Hygiene Management
- Trial name
- NCT07723885
- Testing
- Menstrual health and hygiene intervention
- Where
- Bangladesh
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Halitosis
Evaluation of Clinical and Cost-effectiveness of Different Mouthwashes on Controlling Halitosis Among a Group of Egyptian Children
To evaluate the clinical and cost-effectiveness of mouthwash containing Curcuma longa (Turmeric extract) versus mouthwash containing essential oils and Placebo mouthwash on controlling Halitosis among a group of Egyptian children.
- Trial name
- NCT04905940
- Testing
- Turmeric mouthwash
- Volunteers
- 30 people
- Sponsor
- Cairo University
Myocardial Ischemia, Myocardial Injury
Perioperative Myocardial Ischemia: Troponin Monitoring,Cost-effectiveness, Insights Into Pathophysiology
Background: Despite preoperative screening, technical improvements and increased patient monitoring, perioperative myocardial infarction (PMI) remains the first cause of morbidity and mortality within 30 days after surgery.
- Conditions
- Myocardial Ischemia, Myocardial Injury, Morality
- Trial name
- PMI (NCT03438448)
- Testing
- High sensitive Troponin T monitoring
- Where
- Spain
- Volunteers
- 1,510 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Capacity Building, Support for Midlevel Health Professionals
Integrated Infectious Disease Capacity-Building Evaluation
This evaluation aim is to investigate a cost-effective way to build capacity for the care and prevention of infectious diseases among mid-level practitioners (MLP) in sub-Saharan Africa.
- Conditions
- Capacity Building, Support for Midlevel Health Professionals, Diagnostic Training
- Trial name
- IDCAP (NCT01190540)
- Testing
- Training and supervision, Integrated Management of Infectious Disease (IMID)
- Where
- Uganda
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Washington
Osteoarthritis
Knee Injection RCT
Hypothesis: Ketorolac injection is a cost-effective adjunct in the nonoperative treatment of knee osteoarthritis (OA) compared to steroids and viscosupplementation.
- Trial name
- NCT03694821
- Testing
- Ketorolac Tromethamine Injection, Methylprednisolone Acetate Injection, Hylan G-F 20
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- UConn Health
Frail Elderly, Deaths
Ambulatory Geriatric Evaluation - Frailty Intervention Trial
The main purpose of this randomised controlled trial is to study if a Comprehensive Geriatric Assessment (CGA) and follow up for community-dwelling elderly people can improve outcomes such as health and health-related quality of…
- Trial name
- AGE-FIT (NCT01446757)
- Testing
- The intervention group, control group
- Where
- Sweden
- Volunteers
- 383 people
- Sponsor
- Linkoeping University
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