Clinical trials: Cost-Effectiveness
Strabismus
Mobile Medical Application for Cost-effective Strabismus Screening
Develop and evaluate a new smartphone based app to screen for and measure eye misalignment (strabismus). The investigators will validate the app against simulated strabismus of known magnitude and common clinical tests.
- Trial name
- NCT03450980
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Non Union Diaphyseal Fractures
A Randomized Controlled Cost Study of Infuse BMP 2 vs Iliac Crest Autograft for Non Union of Long Bone Fractures
We are inviting individuals such as yourself, who have diaphyseal fracture (broken bone) with a non union to participate in this research study.
- Trial name
- Infuse (NCT00856479)
- Testing
- Infuse Bone Morphogenic Protein (BMP) 2, iliac crest autograft
- Where
- Canada
- Sponsor
- Ross Leighton
FESD, Rehabilitation
Cost-Effectiveness Analysis of a Rehabilitation Protocol With FES Cycling in Persons With Complete SCI
20 patients were recruited by two hospitals (AOUP and AOUC) in Italy from January 2015 to January 2018. The participants have been addressed to two different groups: the ones recruited by the AOUP were submitted to an…
- Conditions
- FESD, Rehabilitation, Spinal Cord Injuries, Complete Spinal Cord Injury
- Trial name
- NCT04592679
- Testing
- FES-C, Standard Treatment
- Volunteers
- 20 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Hypertension
Controlled Release Nifedipine and Valsartan Combination Therapy in Patients With Essential Hypertension
The primary objective of this study is to investigate incremental cost effectiveness of Nifedipine CR and Amlodipine in combination therapy with Valsartan for the treatment of essential hypertensive patients.
- Trial name
- NCT01518855
- Testing
- Nifedipine (Adalat, BAYA1040), Amlodipine (Norvasc), Diovan
- Where
- 4 sites in Japan
- Volunteers
- 514 people
- Sponsor
- Bayer
Inflammatory Bowel Disease
Effect of Standardized Nutritional Therapy on Clinical Prognosis and Cost-effectiveness of Inflammatory Bowel Disease
To construct a standardized stepped nutritional treatment process for inpatients with inflammatory bowel disease, including nutritional risk screening and assessment, standardized nutritional treatment implementation, therapeutic…
- Trial name
- NCT04349943
- Testing
- nutrition therapy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Severe Personality Disorder
The (Cost-)Effectiveness of Generalist Versus Specialist Treatment for Severe Personality Disorders'
The goal of this clinical trial is to investigate if generalist treatment (GIT-PD) is non-inferior in improving level op personality functioning compared to specialist treatment (MBT/ST) in patients with severe personality…
- Trial name
- P-DAET (NCT06789380)
- Testing
- Schema therapy, Mentalization-based treatment, Guideline-informed treatment for personality disorders
- Where
- 5 sites in Netherlands
- Volunteers
- 358 people
- Sponsor
- Arkin
Pulmonary Disease, Chronic Obstructive, Muscular Atrophy
Nutritional Rehabilitation in Chronic Obstructive Pulmonary Disease (COPD) Patients With Muscle Atrophy
To study in clinically stable Chronic Obstructive Pulmonary Disease (COPD) patients with muscle atrophy: 1. The short-term effects of 4 months exercise training including nutritional supplementation versus exercise training alone…
- Trial name
- NUTRAIN (NCT01344135)
- Testing
- Dietary supplementation, Nutritional counselling, Feedback on physical activity level
- Where
- Netherlands
- Volunteers
- 81 people
- Sponsor
- Maastricht University Medical Center
Schizoaffective Disorder, Schizophrenia
To Determine if Olanzapine is More Cost Effective Than Haloperidol for the Treatment of Schizophrenia
Although currently marketed antipsychotic drugs are useful in the treatment of schizophrenia, efficacy and safety profiles need to be improved.
- Trial name
- NCT00007774
- Testing
- Haloperidol, Olanzapine
- Where
- 18 sites in United States
- Volunteers
- 600 people
- Sponsor
- US Department of Veterans Affairs
Diabetes Mellitus, Polyneuropathies
Cost-effectiveness of In-shoe Pressure Measurement for Therapeutic Shoes
The purpose of this study is determine whether the use of plantar pressure measurements in the production of customized therapeutic footwear for patients with diabetes and a history of foot ulceration results in lower production…
- Trial name
- NCT02061059
- Testing
- block 1, block 2, standard
- Where
- 2 sites in Netherlands
- Volunteers
- 40 people
- Sponsor
- Maastricht University
Dementia
Study of Mirtazapine for Agitation in Dementia
This clinical trial evaluates whether Mirtazapine is more effective than placebo in treating agitation in people with dementia. The trial will assess the safety, clinical and cost effectiveness of the treatment.
- Trial name
- SYMBAD (NCT03031184)
- Testing
- Mirtazapine
- Where
- United Kingdom
- Volunteers
- 207 people
- Sponsor
- University of Sussex
Cervical Cancer
Exploring the Efficacy, Safety and Cost-effectiveness Analysis of Cadonilimab in the Treatment of Cervical Cancer
Cadonilimab, a PD-1/CTLA-4 bi-specific antibody, is being developed by Akeso, Inc. for the treatment of a range of solid tumors, including cervical cancer, lung cancer, gastric/gastroesophageal junction cancer, liver cancer and…
- Trial name
- NCT06140589
- Testing
- Cadonilimab
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fujian Cancer Hospital
Pregnancy
Study of Fetal Health Outcomes: Working With a Missouri E-telehealth Platform (The SHOW-ME Study)
The goal of this clinical trial is to evaluate the potential benefit to patients and providers from using the remote fetal-monitoring system NUVO along with its app to allow for pregnant patients requiring weekly non-stress…
- Trial name
- SHOW-ME (NCT06741735)
- Testing
- INVU fetal monitoring system
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- University of Missouri-Columbia
Diabetic Retinopathy
The Cost-effectiveness of Screening for Diabetic Retinopathy in Hong Kong
Introduction: There is no debate that people with diabetes should be screened for the development of retinopathy which can threaten their sight. However, there is no routine screening for retinopathy in Hong Kong at present.
- Trial name
- NCT01628289
- Testing
- charging a co-payment for Diabetic Retinopathy screening, free screening without charging a co-payment
- Where
- 3 sites in China
- Volunteers
- 4,644 people
- Sponsor
- The University of Hong Kong
Venous Ulcers
Effect of Compressive Therapies on the Healing of Venous Ulcers
The objective of the study is to compare the effect of two treatments on the healing of venous ulcers in follow-up people in two Primary Health Services, in a city in southern Brazil.
- Trial name
- VENOS (NCT04703569)
- Testing
- Dressing with monolayer high compression elastic bandage, Dressing with Unna boot
- Where
- 3 sites in Brazil
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Malaria
Evaluation of the Public Health Impact of Seasonal Intermittent Preventive Treatment (IPT) in Children in Senegal
In areas of seasonal malaria transmission the burden of severe disease and mortality due to malaria is mainly among children under 5 years of age.
- Trial name
- NCT00712374
- Testing
- sulfadoxine-pyrimethamine plus amodiaquine
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Perforated Appendicitis
APPI-Cost Trial for Perforated Appendicitis
The purpose of this study to assess the clinical effectiveness and cost-effectiveness of povidone-iodine (PVI) irrigation in perforated appendicitis, to investigate barriers and facilitators to future implementation of PVI…
- Trial name
- NCT06705842
- Testing
- PVI, Usual Care
- Where
- United States
- Volunteers
- 346 people
- Sponsor
- The University of Texas Health Science Center, Houston
Cancer-related Cognitive Impairment
Electroacupuncture for Cognitive Toxicity in Cancer Survivors: Assessing Implementation, Cost, and Effectiveness for Integration
The goal of this clinical trial is to evaluate the clinical effectiveness and understand the biological mechanisms of electroacupuncture (EA) in reducing cognitive toxicity among cancer survivors.
- Trial name
- EAST-ALIGN (NCT07583979)
- Testing
- True electroacupuncture
- Where
- Singapore
- Volunteers
- 168 people
- Sponsor
- National Cancer Centre, Singapore
Asthma Attack, Lung Function
Cost Effective Air Filtration Intervention in Low-Income Housing to Reduce Asthma Morbidity
This project will investigate the effectiveness of HEPA air cleaners in reducing indoor air pollution and improving asthma morbidity in children living in East Harlem, New York City (NYC).
- Conditions
- Asthma Attack, Lung Function, Airway Inflammation
- Trial name
- NCT07116460
- Testing
- Austin Air Cleaner
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Columbia University
Coronary Disease, Atherosclerosis
Health Coaching to Promote Physical Activity for Coronary Heart Disease Prevention
The purpose of this study is to evaluate the efficacy of motivational interviewing-based coaching to increase physical activity to achieve guidelines recommendations for cardiovascular disease prevention.
- Trial name
- NCT01089842
- Testing
- Health coaching, Usual care
- Where
- Spain
- Volunteers
- 262 people
- Sponsor
- Corporacion Parc Tauli
Midwifery Continuity of Care Model, Maternal Health Outcomes
Impact of Implementing the Midwifery Model of Care on Maternal and Neonatal Health Outcomes in Ethiopia
Background: The Continuity of Midwifery Care (CoMC) is a maternity care model used in some high-income countries. In this model, a dedicated group of midwives supports women throughout pregnancy, labor, and the early postnatal…
- Conditions
- Midwifery Continuity of Care Model, Maternal Health Outcomes, Neonatal Health Outcomes, Cost Effectiveness
- Trial name
- MiMoC (NCT06854705)
- Testing
- Continuity of Midwifery care model, Standard care model
- Volunteers
- 1,654 people, healthy volunteers welcome
- Sponsor
- Debre Berhan University
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