Clinical trials: Cost-Effectiveness
Antimicrobial Stewardship, Cost-effectiveness Analysis
Cost-effectiveness Analysis of an Antimicrobial Stewardship Program in Regione Lombardia (RF-net2018)
Cost-effectiveness analysis of an Antimicrobial Stewardship program in Regione Lombardia: "RF-net2018" is a prospective, experimental, multicenter, pre-post study, whose objectives are the evaluation of the efficiency of economic…
- Trial name
- RF-net2018 (NCT06388278)
- Where
- Italy
- Volunteers
- 50,000 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Hemiparesis
Comparison of Two Rehabilitation Strategies in Patients With Hemiparesis One Year or More After Stroke
In the situation of motor limitations that people often experience after stroke, current health systems cannot provide for the daily amount and duration of high intensity muscle stretch and motor training that would be required…
- Trial name
- NEURORESTORE (NCT02202954)
- Testing
- Guided Self-rehabilitation Contract
- Where
- France
- Volunteers
- 124 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Aging
A Clinical Trial to Determine Outcomes and Cost Effectiveness of Nutritional Intervention in Elderly Patients
With the introduction of the National Insurance Law in Israel in 1995, there have been increased efforts to reduce hospitalization in general and length of stay in the hospital in particular.
- Trial name
- NCT00316966
- Testing
- Multidisciplinary dietary intervention
- Where
- Israel
- Volunteers
- 180 people
- Sponsor
- Soroka University Medical Center
Pulmonary Disease, Chronic Obstructive
COPD Discharge Bundle Delivered Alone or Enhanced Through a Care Coordinator
Chronic obstructive pulmonary disease (COPD) is a common, chronic progressive lung disease that is characterized by shortness of breath, activity limitation, and a predisposition to flare-ups resulting in frequent emergency…
- Trial name
- PRIHS (NCT03358771)
- Testing
- COPD discharge care bundle, COPD discharge care bundle & coordinator
- Where
- 5 sites in Canada
- Volunteers
- 3,710 people
- Sponsor
- University of Alberta
Neurocutaneous Syndromes, Neurofibromatosis Type 1 (NF1)
Precision Medicine for Neurocutaneous Syndromes in Western China
The goal of this observational study (retrospective multicenter cohort study) is to learn if precision medicine approaches-including genetic testing, targeted drugs, and coordinated care from multiple specialists-can improve…
- Conditions
- Neurocutaneous Syndromes, Neurofibromatosis Type 1 (NF1), Tuberous Sclerosis Complex (TSC), Sturge-Weber Syndrome (SWS)
- Trial name
- NCT07327164
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- West China Hospital
Fibromyalgia Syndrome
Cost-utility and Biological Underpinnings of MBSR in Fibromyalgia Syndrome
Purpose: Fibromyalgia syndrome (FMS) is a disabling condition mainly characterized by chronic widespread pain, disturbed sleep, fatigue, and distress.
- Trial name
- EUDAIMON (NCT02561416)
- Testing
- MBSR, FibroQol, TAU
- Where
- Spain
- Volunteers
- 225 people
- Sponsor
- Fundació Sant Joan de Déu
Heart Failure
Routine vs Selective Cardiac Magnetic Resonance in Non-Ischemic Heart Failure
Uncovering the underlying cause of heart failure can be quite challenging and doctors often rely on imaging tests such as echo (heart ultrasound) to provide the answers.
- Trial name
- OUTSMART (NCT01281384)
- Testing
- Advanced Imaging, Standard Imaging
- Where
- 14 sites in Canada, Finland
- Volunteers
- 518 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Knee Osteoarthritis, Rheumatoid Arthritis (RA)
Comparative Study on the Medium- and Long-term Benefits of Prosthesis Selection in Total Knee Arthroplasty
This retrospective real-world study aims to compare the medium- and long-term clinical outcomes, safety, and economic benefits of different knee prosthesis brands used in primary unilateral total knee arthroplasty (TKA) at our…
- Trial name
- NCT07553871
- Volunteers
- 3,500 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Mental Health, Stress Disorders, Post-Traumatic
Integrating Clinical Practice Guidelines for Smoking Cessation Into Mental Health Care for Veterans With Posttraumatic Stress Disorder
The primary study objective is to conduct a prospective, randomized controlled clinical trial that compares the effectiveness of two approaches for delivering smoking cessation treatment for veterans with posttraumatic stress…
- Conditions
- Mental Health, Stress Disorders, Post-Traumatic, Substance-Related Disorders, Tobacco Use Disorder
- Trial name
- NCT00118534
- Testing
- Integrated Care for Smoking Cessation in PTSD patients, Standard of Care
- Where
- 11 sites in United States
- Volunteers
- 943 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Neurodevelpmental Delays, Neurodevelopment
Implementation Outcomes and Cost-effectiveness of Developmental Monitoring for Children Exposed to HIV
The goal of this study is to learn about how to best carry out neurodevelopmental screening methods (tests to see if a young child can use support with brain development) in routine clinic visits in Botswana and Kenya among…
- Conditions
- Neurodevelpmental Delays, Neurodevelopment, Neurodevelopment Outcome
- Trial name
- IMPLEMENT (NCT07457411)
- Testing
- Neurodevelopmental screening
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Washington
Acute Respiratory Distress Syndrome, Acute Lung Injury
Study of the Economics of Pulmonary Artery Catheter Use in Patients With Acute Respiratory Distress Syndrome (ARDS)
Study of the long term outcomes and economic impact of the pulmonary artery catheter in acute respiratory distress syndrome (ARDS/ALI) patients.
- Conditions
- Acute Respiratory Distress Syndrome, Acute Lung Injury, Lung Diseases
- Trial name
- NCT00234767
- Testing
- Pulmonary Artery Catheter, Protocolized Fluid Management
- Volunteers
- 650 people
- Sponsor
- University of Pittsburgh
Contrast Induced Nephropathy, Acute Kidney Injury
A Maastricht Contrast-Induced Nephropathy Guidelines Study: CIN Prevention Guidelines: Appropriate & Cost-effective?
Contrast-induced nephropathy (CIN) is a side-effect of intravascular administration of iodinated contrast material. It is defined as an absolute (>44μmol/l) or relative (>25%) increase in serum creatinine from baseline values…
- Trial name
- AMACING (NCT02106234)
- Testing
- No prophylactic iv hydration
- Where
- Netherlands
- Volunteers
- 660 people
- Sponsor
- Maastricht University Medical Center
Diabetes Mellitus, Type 2
Efficacy and Safety Study of Chromium Picolinate + Biotin on Glucose and Cholesterol Control in T2DM
To evaluate the effect of the combination of chromium picolinate (600 μg Cr) + biotin (2 mg) versus placebo on glycosylated hemoglobin (HbA1c), lipid profiles (Total-C, HDL-C, LDL-C, TGs, TG/HDL ratio, etc), and pharmacoeconomic…
- Trial name
- NCT00289354
- Testing
- Chromium Picolinate (600 mcg Cr) + biotin (2 mg)
- Volunteers
- 600 people
- Sponsor
- Nutrition 21, Inc.
Mental Stress
The Effectiveness and Cost-effectiveness of Mental Wellness Youth Hub
The proposed study is to be carried out with 6000-7000 youths aged 12 - 24 in Hong Kong. The purpose of the study is to investigate the effectiveness and cost-effectiveness of a Hub project for young people: LevelMind@JC.
- Trial name
- NCT04840303
- Testing
- LevelMind@JC Mental Wellness Youth Hubs
- Where
- Hong Kong
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
HIV Infections, Adherence, Medication
Supporting Sustained HIV Treatment Adherence After Initiation
The investigators will implement a 24-month fractional factorial design study (Aim 1). The investigators will recruit 510 patients initiating antiretroviral therapy (ART) at three City of Cape Town ART clinics.
- Trial name
- SUSTAIN (NCT05040841)
- Testing
- M1/OTR: Immediate outreach to subject due to unsuppressed viral load test result, M2/PRM: Immediate outreach to subject after a missed pharmacy refill, M3/EAM: Immediate outreach to subject after EAM-identified missed doses
- Where
- 3 sites in South Africa
- Volunteers
- 534 people
- Sponsor
- Boston University
Hypertensive Disorders of Pregnancy
Pregnancy Salt Substitution Trial for Hypertensive Disorders of Pregnancy Prevention (PREG-Salt)
The PREG-Salt study is to evaluate the effect, safety and cost-effectiveness of low-sodium salt in reducing blood pressure and preventing hypertensive disorders in pregnant women at high risk in China.
- Trial name
- PREG-Salt (NCT07294807)
- Testing
- Potassium-enriched salt substitute, Usual salt
- Where
- 110 sites in China
- Volunteers
- 3,200 people
- Sponsor
- Peking University
mHealth Intervention
Evaluation of a Mobile Health Intervention to Improve Sexual and Reproductive Health Outcomes Among Kenyan Adolescents Living in Urban Informal Settlements
This two-year study evaluates a mobile phone-based comprehensive sexuality education program designed to support adolescent sexual and reproductive health in Kenya, where rates of teenage pregnancy and sexually transmitted…
- Trial name
- NCT07587281
- Testing
- Chatbot providing comprehensive sexuality education plus youth peer facilitators
- Where
- Kenya
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Eating Disorders in Adolescence, Food Addiction
Evaluation of a Digital School-Based Intervention for the Primary Prevention of Eating Disorders in Pre-Adolescents (PRETA Program)
Background: Eating Disorders (ED) are mental health conditions, characterized by pathological behaviors toward food intake or a persistent obsession with weight control.
- Trial name
- PRETA (NCT06792981)
- Testing
- Universal primary prevention program based on ICTs
- Where
- Spain
- Volunteers
- 1,068 people
- Sponsor
- Servicio Canario de Salud
Surgery
A Cost Effectiveness Analysis of Robotic Versus Laparoscopic Distal Pancreatectomy
This is a clinical and cost-effectiveness analysis within a retrospective comparative study of RDP and LDP conducted at Sanchinarro University Hospital from 2011 to 2017.
- Trial name
- NCT03989739
- Testing
- Da Vinci
- Volunteers
- 59 people
- Sponsor
- Fundación de investigación HM
Diabetes Mellitus Type 2
(Cost-)Effectiveness of SLIMMER Diabetes Prevention Intervention
The overall aim of the project is to evaluate the (cost-)effectiveness of the SLIMMER diabetes prevention intervention in Dutch primary health care.
- Trial name
- SLIMMER (NCT02094911)
- Testing
- Combined lifestyle intervention, Usual care group
- Where
- Netherlands
- Volunteers
- 316 people
- Sponsor
- Wageningen University
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