Clinical trials: Cost-Effectiveness
Radiculopathy, Cervical, Myelopathy Cervical
Cervical Arthroplasty Cost Effectiveness Study (CACES)
To date, no consensus exists on which anterior surgical technique is more cost-effective to treat cervical degenerative disc disease (CDDD).
- Conditions
- Radiculopathy, Cervical, Myelopathy Cervical, Myelopathy, Compressive, Radiculopathy, Cervical Region
- Trial name
- CACES (NCT04623593)
- Testing
- ACDF, ACDA
- Where
- Netherlands
- Volunteers
- 198 people
- Sponsor
- Valérie Schuermans
Cardiopulmonary Resuscitation
Improving CPR Quality With Longitudinal Practice and Realtime Feedback - RCT With CEA
Objectives: The primary objective of this project is to assess whether the implementation of a new cardiopulmonary resuscitation (CPR) training program (longitudinal training with real-time feedback) can improve CPR quality of…
- Trial name
- NCT02539238
- Testing
- Longitudinal practice and real-time feedback
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- Alberta Children's Hospital
Low Back Pain
Walking Away From Back Pain, One Step at a Time
This study will investigate if a 12-week, individually-tailored walking program, using pedometers will be a more clinically and cost-effective option for the management of chronic low back pain than standardized advice and…
- Trial name
- NCT02284958
- Testing
- Standard, Walking
- Where
- Canada
- Volunteers
- 174 people
- Sponsor
- University of Saskatchewan
Cocaine Dependence
Effectiveness and Costs of Enhanced Cocaine Treatments
The study will evaluate the effectiveness, economic benefits, and costs of voucher reinforcement for cocaine and alcohol abstinence, additional counseling services, and their combination in a sample of cocaine dependent patients…
- Trial name
- NCT00167258
- Testing
- Voucher Reinforcement, Extra Counseling Services, Voucher Reinforcement + Extra Counseling Services
- Where
- United States
- Sponsor
- University of Pennsylvania
Dementia
Study of Mirtazapine for Agitation in Dementia
This clinical trial evaluates whether Mirtazapine is more effective than placebo in treating agitation in people with dementia. The trial will assess the safety, clinical and cost effectiveness of the treatment.
- Trial name
- SYMBAD (NCT03031184)
- Testing
- Mirtazapine
- Where
- United Kingdom
- Volunteers
- 207 people
- Sponsor
- University of Sussex
Headache, Physical Activity
Exercise Training With Physically Active Lifestyle to Reduce Headache and Quality of Life
The aim of this intervention study is to examine whether tailored exercise therapy training is effective and cost-effective to decrease headache frequency and intensity, reduce medication used for chronic headache and patients´…
- Conditions
- Headache, Physical Activity, Quality of Life
- Trial name
- HEADEX (NCT01664585)
- Testing
- Training group, Control
- Where
- 3 sites in Finland
- Volunteers
- 116 people
- Sponsor
- UKK Institute
Depressive Disorder
Effectiveness of a Brief Psychological Mindfulness Based Intervention for the Treatment of Depression in Primary Care
The aim of this study is to assess and compare a mindfulness low-intensity (4 weeks) psychological intervention for the treatment of depression in Primary Care between different groups: a mindfulness intervention applied face to…
- Trial name
- NCT03034343
- Testing
- Mindfulness
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Universitat Jaume I
Atrial Flutter
Catheter Ablation as the First Line Therapy for Typical Atrial Flutter
Catheter ablation of typical atrial flutter is a well established technique with a high acute success rate and very low complication and recurrence rates.
- Trial name
- NCT00213408
- Testing
- Radiofrequency catheter ablation of typical atrial flutter
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Rouen
Stroke, eHealth
Effect of Occupational Therapy at Home E-Rehabilitation (OTHER) for Persons Post-stroke
The goal of this (cost)effectiveness study is to compare care as usual with OTHER-intervention in Cerebro Vascular Accident (CVA) older adults in Geriatric Rehabilitation (GR). The main question[s] it aims to answer are: 1.
- Conditions
- Stroke, eHealth, Occupational Therapy
- Trial name
- OTHER (NCT05855226)
- Testing
- OTHER-intervention (Occupational Therapy at Home E-Rehabilitation)
- Where
- 9 sites in Netherlands
- Volunteers
- 116 people
- Sponsor
- Amsterdam University of Applied Sciences
Peripheral Arterial Occlusive Disease, Chronic Total Occlusion of Artery of the Extremities
Prospective Study of the SoundBite™ Crossing System in Complex Peripheral CTOs
This study aims at assessing additional performance characteristics of the SoundBite™ Crossing System with regards to the luminal passage of complex Chronic Total Occlusions (CTO) by evaluating clinically relevant efficacy…
- Trial name
- PROSPECTORII (NCT03933657)
- Testing
- SoundBite™ Crossing System - Peripheral
- Where
- 2 sites in Austria, Germany
- Sponsor
- SoundBite Medical Solutions, Inc.
Pancreatitis, Acute, Crohn Disease
Cost Effectiveness of an Intervention in Hospitalized Patients With Disease-related Malnutrition
Objectives: To evaluate the effectiveness, and cost-effectiveness, of three hospitalized patient care strategies in relation to disease-related malnutrition (DRM) hospital admissions based on results such as length of stay of the…
- Conditions
- Pancreatitis, Acute, Crohn Disease, Ulcerative Colitis, Inflammatory Bowel Diseases
- Trial name
- NCT04188990
- Testing
- Nutritional dietary intervention, By demand, Usual current care
- Where
- 2 sites in Spain
- Volunteers
- 1,051 people
- Sponsor
- Hospital Galdakao-Usansolo
Challenging Behaviour
Clinical and Cost Effectiveness of Positive Behaviour Support: a Trial
Many people with intellectual disability have challenging behaviour which often has serious consequences such as the prescription of long term medication, in-patient admissions and disruption of normal daily activities.
- Trial name
- PBS (NCT01680276)
- Testing
- PBS based staff training, Treatment as Usual
- Where
- 3 sites in United Kingdom
- Volunteers
- 246 people
- Sponsor
- University College, London
Mass Screening, Colorectal Cancer
SMS Messaging as a Tool to Improve Cancer Screening Programs
The aim of this project is to assess the impact on health and economics of the implementation of text messaging (SMS) in cancer screening programs. Three interventions with SMS will be evaluated through community trials.
- Conditions
- Mass Screening, Colorectal Cancer, Breast Cancer
- Trial name
- M-TICS (NCT04343950)
- Testing
- SMS reminders to enhance colorectal cancer screening, SMS reminders to return the fecal immunochemical test at the pharmacy in CRC screening:, Invitation by SMS to previous participants in breast cancer screening:
- Where
- Spain
- Volunteers
- 44,601 people, healthy volunteers welcome
- Sponsor
- Institut Català d'Oncologia
Obstructive Sleep Apnoea (OSA)
A Study Assessing Adult Patients Referred to an NHS Sleep Service With Suspected Obstructive Sleep Apnoea. This Study Aims to Compare the Sunrise Wearable Diagnostic Device Performance and Potential Inclusion in a NHS Diagnostic Pathway With Oximetry and WatchPAT Which Are Currently Used.
The goal of this clinical trial is to evaluate whether the Sunrise device (that measure small jaw movements) can improve the diagnosis and management of Obstructive Sleep Apnoea (OSA) in adults (≥ 18 years) referred to a Sleep…
- Trial name
- SOSA (NCT07269483)
- Testing
- WatchPAT 300, Oximetry, Sunrise
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Virginia Hawkins
Hyperaldosteronism
SPARTACUS: Subtyping Primary Aldosteronism: a Randomized Trial Comparing Adrenal Vein Sampling and Computed Tomography Scan.
Rationale: Primary hyperaldosteronism (PA) is the most frequent form of secondary hypertension. In PA autonomous hypersecretion of aldosterone by one or both adrenal glands causes hypertension that is often refractory to…
- Trial name
- SPARTACUS (NCT01096654)
- Testing
- Ct-scan or adrenal vein sampling
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Radboud University Medical Center
Diabetes
The Cost-efficacy of Psychological Intervention for Strengthening Parental Authority Among Parents of Diabetic Adolescents With Poor Glycemic Control
A three arms, open, randomized interventional study including 100 participants in order to evaluate the cost-efficacy of psychological intervention for strengthening parental authority among parents of diabetic adolescents with…
- Trial name
- NCT00622856
- Testing
- psychological intervention, Diabetes education
- Where
- Israel
- Volunteers
- 55 people
- Sponsor
- Rabin Medical Center
Ankle Sprain, Ankle Sprain 1St Degree
Effectiveness of a Telerehabilitation Program in Ankle Sprain
Ankle sprain is the most common sprain. Their care entails a high cost due to the incapacity for work that it generates. An early and timely intervention for the treatment of ankle sprain reduces the days of disability and…
- Conditions
- Ankle Sprain, Ankle Sprain 1St Degree, Ankle Sprain 2Nd Degree
- Trial name
- NCT05217173
- Testing
- telerehabilitation
- Where
- Mexico
- Volunteers
- 82 people
- Sponsor
- Instituto Mexicano del Seguro Social
Chemotherapy-induced Neutropenia, Febrile Neutropenia, Drug-Induced
Granulocyte Colony Stimulating Factor for for the Prevention of Febrile Neutropenia in Epithelial Ovarian Cancer
This study aims to analyze the effects of long-acting versus short-acting granulocyte colony stimulating factor (G-CSF) on the prevention febrile neutropenia (FN) in epithelial ovarian cancer patients.
- Conditions
- Chemotherapy-induced Neutropenia, Febrile Neutropenia, Drug-Induced, Epithelial Ovarian Cancer, Colony Stimulating Factors Adverse Reaction
- Trial name
- NCT04101760
- Testing
- Long-acting granulocyte colony stimulating factor, Short-acting granulocyte colony stimulating factor
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Lei Li
Smoking Cessation, Pharmacist-Patient Relations
Cost-effectiveness of a Tobacco Cessation Care Service in the Community Pharmacy
The study was a non-randomized controlled trial of 12-months' follow-up with 182 Spanish community pharmacists. Intervention community pharmacists received the CESAR training to improve their smoking cessation services…
- Trial name
- CESAR (NCT05461066)
- Testing
- CESAR training
- Volunteers
- 800 people
- Sponsor
- Sociedad Espanola de Farmacia Clinica, Familiar y Comunitaria
Staphylococcal Infections
Cost-Effectiveness Study Comparing Chlorhexidine Bathing With Active Surveillance Cultures to Prevent Methicillin-resistant Staphylococcus Aureus & Other Hospital Infections
This pilot study in our medical intensive care unit will evaluate the clinical and cost-effectiveness of an active surveillance program for methicillin-resistant Staphylococcus aureus (MRSA), compared to routine daily bathing…
- Trial name
- NCT00779246
- Testing
- Nasal swabs for MRSA culture, Chlorhexidine gluconate, Contact isolation
- Where
- United States
- Volunteers
- 1,518 people
- Sponsor
- Christiana Care Health Services
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