Clinical trials: Cost-Effectiveness
Infertility
The Cost-effectiveness of Hysterosalpingography Versus Hysterosalpingo-foam Sonography During Fertility Work-up
Hysterosalpingography (HSG) and hysterosalpingo-foam sonography are two methods to assess tubal patency during fertility work-up.
- Trial name
- FOil (NCT05882188)
- Testing
- Oil-based contrast, ExEm Foam
- Where
- Netherlands
- Volunteers
- 1,102 people
- Sponsor
- Amsterdam UMC, location VUmc
Neoplasms, Unknown Primary
Cost-effectiveness Study of miRview™ Mets in Patients With Cancer of Unknown Primary (CUP)
The aim of the study is in cancer of unknown primary (CUP) patients, to compare the cost-effectiveness of miRview™ mets test with conventional work-up in identifying the primary tumor site.
- Trial name
- NCT01202786
- Where
- 3 sites in Israel
- Volunteers
- 60 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Type 1 Diabetes
Use of Continuous Glucose Monitoring Devices Among People Living With Type 1 Diabetes in South Africa
Diabetes mellitus (diabetes) is a chronic condition that represents a major public health and clinical concern. Self-monitoring of blood glucose (SMBG) is a critical part of the care of individuals with diabetes.
- Trial name
- ACCEDE (NCT05944718)
- Testing
- Continuous glucose monitor
- Where
- 3 sites in South Africa
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Malaria
Estimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generated During Piloted New Net Distributions in Burkina Faso
The use of insecticide-treated bed nets (ITN) has contributed to the substantial reduction in malaria cases and deaths. This progress is threatened by increasing resistance commonly used insecticides in mosquito populations.
- Trial name
- NCT04157894
- Testing
- Standard long-lasting insecticidal net, Chlorfenapyr insecticide treated net, Piperonyl butoxide long-lasting insecticidal net
- Where
- Burkina Faso
- Volunteers
- 5,606 people, healthy volunteers welcome
- Sponsor
- PATH
Heart Failure
A Multifaceted Nurse-based Strategy Reduces HEart FaiLure Morbidity in PatiENts Admitted for Acute Decompensated Heart Failure in Brazil
The home based intervention is a multidisciplinary approach that has shown benefit in the follow-up of patients with Heart Failure (HF).
- Trial name
- HELEN II (NCT01213875)
- Testing
- Home based education
- Where
- Brazil
- Volunteers
- 252 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Suicide, Attempted, Suicidal Ideation
Differences Between Suicide Attempters and Suicide Ideators. Influence of the Brief Therapy Attempted Suicide Short Intervention Program (ASSIP) on Neuropsychological Correlates and Psychological Process Factors - Project 3
The present study consists of 3 projects in total. It aims to investigate the (neuro-) psychological patterns from suicidal ideation to suicidal behavior as well as the feasibility and cost-effectiveness of ASSIP flex.
- Conditions
- Suicide, Attempted, Suicidal Ideation, Feasibility, Cost-effectiveness
- Trial name
- NePsyAssip HT (NCT06322199)
- Testing
- ASSIP (Attempted Suicide Short Intervention Program) flex
- Where
- 4 sites in Switzerland
- Volunteers
- 119 people
- Sponsor
- University of Bern
Costs and Cost Analysis, Effectiveness
Hospital at Home Versus Inpatient Care: Costs and Effectiveness
Background and Objectives Hospital at Home (HaH) delivers hospital-level treatment to acutely ill patients in their own homes, including daily medical and nursing visits, infusions, physiotherapy, and diagnostics.
- Conditions
- Costs and Cost Analysis, Effectiveness, Patient Satisfaction
- Trial name
- NCT07274072
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Hospital at Home AG
Trauma and Stressor Related Disorders, Post-traumatic Stress Disorders
Posttraumatic Stress Disorders in Police, Correctional Service Officers, and 911 Operators
Police officers, correctional service officers, and 911-operators are at increased risk for suffering from trauma-related disorders due to their direct and indirect exposure to life-threatening events, such as shootings, violent…
- Conditions
- Trauma and Stressor Related Disorders, Post-traumatic Stress Disorders, Adjustment Disorders, Acute Stress Disorder
- Trial name
- NCT03152175
- Testing
- Propranolol Hydrochloride
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Douglas Mental Health University Institute
Antimicrobial Resistance
Efficacy and Cost-effectiveness of Hospital Antimicrobial Stewardship Programs
The main objective of the project is to evaluate the efficiency and cost-effectiveness of different strategies aiming at optimizing antibiotic prescribing in hospitals.
- Trial name
- CEFECA (NCT02814877)
- Testing
- promotion of appropriate use of antibiotics in hospital
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breathless Patients With Any Established Underlying Medical Diagnosis
Development of King's College Hospital Breathlessness Service
Breathlessness is a common, distressing symptom in advanced malignant and non malignant disease, and impacts significantly on quality of life.
- Trial name
- NCT01165034
- Testing
- Breathlessness Support Service
- Where
- United Kingdom
- Volunteers
- 110 people
- Sponsor
- King's College London
Remote Consultation, Teleconsultation, Remote Consultation, Video
Evaluation of Videoconferencing Versus Telephone Genetic Counseling
Genetic counseling has benefits for individuals and their family members in their health care decision-making. Provision of genetic counseling has been deemed standard of care by several medical organizations and incorporated…
- Trial name
- EVTGC (NCT02108977)
- Testing
- Videoconferencing Genetic Consultation, Teleconferencing Genetic Consultation
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- VA Office of Research and Development
Inflammation, Gastroesophageal Reflux
Trial to Assess the Effectiveness of Educational Outreach in Prescription Guidelines
Background: The Portuguese National Health Directorate has issued clinical practice guidelines on prescription of anti-inflammatory drugs and COX-2 inhibitors, acid suppressive therapy and proton pump inhibitors, and…
- Conditions
- Inflammation, Gastroesophageal Reflux, Gastrointestinal Diseases, Cardiovascular Diseases
- Trial name
- TEP (NCT01984034)
- Testing
- Educational Outreach Visits, Passive Dissemination
- Where
- Portugal
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universidade Nova de Lisboa
Breast Cancer
Cost-Effectiveness of Abdominal-based Autogenous Tissue vs Tissue Expander-Implant Reconstruction - A Feasibility Study
It is estimated that about 25% and 40% of health care expenditures in Canada and USA respectively are wasted because of inefficiencies and not practicing evidence-based medicine.
- Trial name
- NCT02438449
- Testing
- Breast Reconstruction Surgery
- Where
- Canada
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- McMaster University
Cardiovascular Diseases, Dyslipidemias
Efficacy, Safety and Cost-efficacy of a Pre-emptive Genotyping Strategy in Patients Receiving Statins
This is a Phase IV multicentre adaptive single-blinded randomized clinical trial if preemptively genotyping populations at risk of cardiovascular disease susceptible of receiving high or moderate doses of statin therapy is…
- Conditions
- Cardiovascular Diseases, Dyslipidemias, Statin Adverse Reaction, Pharmacogenic Myopathy
- Trial name
- PREVESTATGx (NCT06262685)
- Testing
- Preemptive pharmacogenetic atorvastatin dose based on CPIC guidelines, Preemptive pharmacogenetic simvastatin dose based on CPIC guidelines, Preemptive pharmacogenetic pitavastatin dose based on CPIC guidelines
- Where
- Spain
- Volunteers
- 216 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Cancer
S1204, Viral Screening in Newly Diagnosed Cancer Patients
The goal of this study is to estimate the prevalence of HIV, Hepatitis B and hepatitis C infection among newly diagnosed cancer patients presenting to community and academic oncology clinics.
- Trial name
- NCT01946516
- Where
- 58 sites in United States
- Volunteers
- 3,051 people
- Sponsor
- SWOG Cancer Research Network
Overall Functioning, Incremental Cost-effectiveness Ratio
The CareWell-programme for Community-dwelling Frail Elderly Persons.
The purpose of this study is to investigate the effect of the CareWell-programme on overall functioning of community-dwelling frail elderly persons.
- Trial name
- CareWell (NCT01499797)
- Testing
- The CareWell programme
- Where
- 10 sites in Netherlands
- Volunteers
- 536 people
- Sponsor
- Radboud University Medical Center
Emotional Disorder, Anxiety Disorders
Unified Protocol for Treatment of Emotional Disorders in Brief Groups in Primary Care Services in Spain
The aim of this project is to contribute to the improvement of psychological care received in primary care (PC), through the study of the cost-effectiveness and acceptability of the Unified Protocol for the treatment of emotional…
- Conditions
- Emotional Disorder, Anxiety Disorders, Depressive Disorder
- Trial name
- NCT06547450
- Testing
- 5-session UP condition, 8-session UP condition
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
HIV Infections
Implementation a Data-to-Care Strategy to Improve HIV Continuum Outcomes for Out of Care People Living With HIV (PLWH) in Ukraine
The goal of this clinical trial is to study the preliminary effectiveness of a data to care intervention versus standard of care for people living with HIV in Ukraine.
- Trial name
- NCT05821413
- Testing
- Data to care, Standard of Care
- Where
- Ukraine
- Volunteers
- 160 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Obstructive Sleep Apnea
Validity of a Home Respiratory Polygraphy for the Diagnosis of Obstructive Sleep Apnea in Children (DINISAS)
To assess the diagnostic validity and cost-effectiveness of a home respiratory polygraphy (HRP) performed at home compared with the standard polysomnography (PSG) in children with clinically suspected Obstructive Sleep Apnea…
- Trial name
- DINISAS (NCT03449550)
- Testing
- Home Respiratory Polygraphy (HRP), Standard Polysomnography (PSG)
- Where
- Spain
- Volunteers
- 320 people
- Sponsor
- Hospital Universitario Araba
Speech Therapy, Speech Disorders in Children
High-intensity vs Low-intensity Speech Intervention in Children With Phonological Speech Sound Disorders
Achieving speech that is understandable and acceptable to others is the key outcome in the treatment of phonological speech sound disorders. Therefore, speech therapy provided by a speech-language pathologist is essential.
- Conditions
- Speech Therapy, Speech Disorders in Children, Phonological (Speech) Disorder
- Trial name
- NCT07779759
- Testing
- High-intensity combined phonetic-phonological intervention, Low-intensity combined phonetic-phonological intervention
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- University Ghent
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