Clinical trials: Cost-Effectiveness
Educational Problems, Resuscitation
Group Size in Basic Life Support (BLS) Courses
Basic Life Support (BLS) is important for outcome in cardiac arrest.Therefore, it is crucial to improve the quality of education in resuscitation training.
- Trial name
- NCT03773861
- Testing
- errors made in one BLS session
- Where
- Switzerland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Multiple Sclerosis
Treadmill Training in Chronic MS: Efficacy and Cost-effectiveness
The purpose of the study is to determine whether treadmill training is safe and beneficial in patients with walking difficulty because of multiple sclerosis.
- Trial name
- NCT00334100
- Testing
- Exercise
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Pelvic Organ Prolapse, Cystocele
Effectiveness Prolift+M Versus Conventional Vaginal Prolapse Surgery
Pelvic organ prolapse is highly prevalent in the female population. The recurrence rate of pelvic organ prolapse after surgical treatment is high.
- Conditions
- Pelvic Organ Prolapse, Cystocele, Rectocele, Uterine Prolapse
- Trial name
- VROUW2 (NCT02231099)
- Testing
- Prolift + M, conventional vaginal prolapse surgery
- Where
- 5 sites in Netherlands
- Volunteers
- 176 people
- Sponsor
- Radboud University Medical Center
Morbid Obesity Requiring Bariatric Surgery
SAPI vs SASI in the Management of Morbid Obesity
Study Design A single-center cohort study combining prospective and retrospective data collection was conducted. The prospective arm enrolled consecutively admitted patients, while the retrospective arm analyzed previously…
- Trial name
- NCT07618598
- Testing
- Single Anastomosis Sleeve Ileal (SASI) Bypass Procedure, Single Anastomosis Plication Ileal (SAPI) Bypass Procedure
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Mansoura University
Cancer, Neoplasm
Enhancing Successful Return to Work of Employees With Cancer, by Supporting Employers (MiLES Intervention)
The objective of this randomized controlled trial (RCT) is to evaluate the effectiveness of the MiLES intervention targeted at employers, on successful return to work (RTW) of employees with cancer, compared to care as usual…
- Trial name
- MiLES (NCT06672887)
- Testing
- MiLES
- Where
- 5 sites in Netherlands
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Obesity, Bariatric Surgery
Effectiveness of a Modified Cost-Effective Dietary Plan in Promoting Weight Loss and Preservation of Lean Body Mass in Patients After Bariatric Surgery
This study will see if a low-cost dietary plan, based on the standard dietary guidelines of the American Society for Metabolic and Bariatric Surgery (ASMBS) and using locally available foods, can help patients lose weight and…
- Conditions
- Obesity, Bariatric Surgery, Nutritional Status, Body Composition
- Trial name
- NCT07111767
- Testing
- Low-Cost Post-Bariatric Diet, Standard High-cost Post-Bariatric Diet
- Where
- Pakistan
- Volunteers
- 122 people
- Sponsor
- Khyber Teaching Hospital
Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction
Clinical Impact of Using IMPROVE to Select Patients for Carotid Revascularisation
Narrowing of the carotid artery due to atherosclerosis with an unstable plaque can cause a stroke. Patients with carotid artery disease who have had a TIA or minor stroke and are at high risk of another stroke are often treated…
- Conditions
- Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction, Stroke Ischemic, Atheroscleroses
- Trial name
- IMPROVE (NCT07556887)
- Testing
- IMPROVE Risk Model
- Where
- 10 sites in Netherlands
- Volunteers
- 613 people
- Sponsor
- Maastricht University Medical Center
CYP2D6, Psychiatric Patients
Cost-effectiveness of CYP2D6 and CYP2C19 Genotyping in Psychiatric Patients in Curacao
The cytochrome P450 (CYP) is a group of metabolic enzymes, from which the 2D6 and CYP2C19 polymorphisms are specifically related to the metabolism of psychiatric drugs.
- Trial name
- NCT02713672
- Testing
- Dose adjustment according to genotype
- Where
- Netherlands
- Volunteers
- 86 people
- Sponsor
- GGZ Centraal
Psoriasis
Home UVB Phototherapy for Psoriasis: Effectiveness, Quality of Life and Cost-Effectiveness
UVB phototherapy is a commonly used treatment for patients with psoriasis. Generally it is performed in the outpatient department of the hospital.
- Trial name
- NCT00150930
- Testing
- narrowband UVB phototherapy at home
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- UMC Utrecht
Scalp Laceration
Comparison Study on Hair Apposition Technique Performed Between Nurses and Doctors in Emergency Department.
The purpose of this study is to compare the effectiveness, complications and benefits of Hair Apposition Technique(HAT)performed by nurses or doctors.
- Trial name
- NCT00353769
- Testing
- Hair Apposition Technique
- Where
- Singapore
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Fever, Anaemia
Acceptability and Cost Effectiveness of Home Based Management of Fever: Different Strategies
Malaria remains a major cause of morbidity and mortality particularly among children < 5 years in Uganda. Due to inaccessibility many children die before they reach the health facility.
- Conditions
- Fever, Anaemia, Malaria
- Trial name
- NCT00259142
- Testing
- Chloroquine, sulphadoxine-pyrimethamine
- Where
- Uganda
- Volunteers
- 1,314 people
- Sponsor
- DBL -Institute for Health Research and Development
Multiple Sclerosis
Multiple Sclerosis Self Monitoring Study
This study is a multicenter, prospective, randomized controlled trial (RCT) to compare the effectiveness of a smartphone-based self-monitoring and self-management tool on control self-efficacy with respect to standard clinical…
- Trial name
- MSSM (NCT06125301)
- Testing
- MS Sherpa
- Where
- Netherlands
- Volunteers
- 225 people
- Sponsor
- Amsterdam UMC, location VUmc
Frail Older Adults
Is Multifactorial Nutritional Treatment for Undernutrition in Older Adults in Primary Care Cost-effective?
The hypothesis is that there is a profit potential by implementing a multifactorial nutritional intervention among frail elderly since this will result in an improved nutritional status, functional capacity and improved quality…
- Trial name
- CES (NCT01873456)
- Testing
- multifactorial nutritional intervention
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital at Herlev
Chest Pain, CAD
Comparing a Diagnostic and Treatment Strategy of Upfront CTCA With SOC in Patients With Chest Pain and Suspected CAD
Rationale: Patients with chest pain usually undergo multiple diagnostic examinations to demonstrate or rule out atherosclerotic coronary artery disease (CAD).
- Trial name
- CLEAR-CAD (NCT05344612)
- Testing
- CT Coronary Angiography
- Where
- Netherlands
- Volunteers
- 6,444 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Venous Leg Ulcer, Diabetic Foot Ulcer
Clinical Performance and Cost Effectiveness of Biatain® Silicone Compared With Standard of Care
A randomised controlled investigation comparing the clinical performance and cost effectiveness of Biatain® Silicone with Standard of Care dressing including filler in chronic wounds (CP351 - BISIL Study) This study (BISIL) will…
- Trial name
- BISIL (NCT05786612)
- Testing
- Biatain® Silicone, Mepilex Border with Aquacel Extra Hydrofiber
- Where
- 9 sites in United Kingdom
- Volunteers
- 102 people
- Sponsor
- Coloplast A/S
Breast Cancer
Digital Tool for Psychological Support in Women With Breast Cancer
This study will design, test, and evaluate SerenApp, a digital health tool created to support women after completing treatment for breast cancer.
- Trial name
- SerenApp (NCT07169539)
- Testing
- SerenApp Digital Psychological Intervention
- Where
- 2 sites in Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Costa del Sol
Sexually Transmitted Infection, HIV
Repeat Sexually Transmitted Infection (STI) Patients: Tailored Socio-Contextual Intervention to Reduce HIV Risk
People who present repeatedly at Sexually Transmitted Infection (STI) clinics represent a key population for HIV prevention intervention research.
- Trial name
- NCT01510262
- Testing
- Tailored Socio-Contextual Intervention, Standard of Care
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University of Wisconsin, Milwaukee
HCC - Hepatocellular Carcinoma
Recurrence Patterns and Cost-Effectiveness of Surgical Approaches in Early-Stage Hepatocellular Carcinoma
This study aims to investigate the recurrence patterns and cost-effectiveness of robotic-assisted, laparoscopic, and open liver resections in patients with early-stage (BCLC 0/A) hepatocellular carcinoma.
- Trial name
- NCT06776185
- Testing
- Liver Surgery
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Chen Xiaoping
Acute Appendicitis
Cost-effectiveness Analysis and Case-based Payment Norm Modeling on Appendicitis Patients at Hanoi Medical University Hospital
In the world, there are several studies comparing the cost-effectiveness between laparoscopic appendectomy and open appendectomy.
- Trial name
- NCT03504878
- Testing
- Laparoscopic appendectomy, Open appendectomy
- Where
- Vietnam
- Sponsor
- Hanoi Medical University
Stable Ischemic Heart Disease, Coronary Artery Disease
Evaluation of Diagnostic Accuracy, Safety, and Cost-Effectiveness of the Non-Invasive Cardiolens FFR-CT Pro Method to Measure the Fractional Flow Reserve in Diagnostics of Chronic Coronary Syndromes Versus the Standard Diagnostic Modalities.
A multicentre, post-marketing, observational trial in 450 patients, whose standard diagnostic workup for chronic coronary syndromes provided for Invasive Coronary Angiography (ICA).
- Trial name
- NCT04777513
- Testing
- CCTA (Coronary Computed Tomography Angiography), ICA (Invasive Coronary Angiography), FFR (Fractional Flow Reserve)
- Where
- 11 sites in Poland
- Volunteers
- 450 people
- Sponsor
- Hemolens Diagnostics Sp. z o.o.
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