Clinical trials: Cost-Effectiveness
Arthropathy of Knee
Protocol for a Multicenter Study on (Cost)Effectiveness of the Back At Work After Surgery (BAAS): a Clinical Pathway for Knee Arthroplasty
Background Optimizing return to work (RTW) after knee arthroplasty (KA) is becoming increasingly important due to a growing incidence of KA and poor RTW outcomes after KA.
- Trial name
- NCT05690347
- Testing
- Back At work After Surgery (BAAS)
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Low Back Pain, Neck Pain
Which Model of Care is the Most Cost-effective in the Treatment of Musculoskeletal Disorders?
As musculoskeletal disorders (MSKDs) reach epidemic proportions in Canada, access to the public health system for those who suffer from them is increasingly difficult.
- Conditions
- Low Back Pain, Neck Pain, Anterior Knee Pain Syndrome, Rotator-cuff Related Shoulder Pain
- Trial name
- Edu1st (NCT06832852)
- Testing
- Stepped care, Rehabilitation Care, Medical Care
- Where
- Canada
- Volunteers
- 369 people
- Sponsor
- Laval University
COPD
Pulmonary Rehabilitation at Home Versus at the Gymnasium
Short term efficacy of pulmonary rehabilitation for improving functional capacity and quality of life of chronic obstructive respiratory disease (COPD) patient is well known.
- Trial name
- NCT00169897
- Testing
- Pulmonary rehabilitation (teaching and exercise)
- Where
- 10 sites in Canada
- Volunteers
- 252 people
- Sponsor
- Laval University
Neck Pain, Chronic Pain
The NEXERCISE-trial: Reshaping Exercise Programs for Patients With Non-specific Neck Pain
The Nexercise-trial is a blended treatment program for patients with chronic non-specific neck pain. We will investigate whether a blended treatment approach, combining specific neck exercises and general aerobic exercises, has…
- Trial name
- NEXERCISE (NCT04749823)
- Testing
- Blended treatment program, Specific strength exercise program, General aerobic exercise program
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- University Ghent
Depression, Chronic Disease (Diabetes/Low Back Pain)
Efficacy of a Blended Low Intensity Internet-delivered Psychological Program in Patients With Multimorbidity in Primary Care.
The aim of this study is to assess the efficacy in Primary Care (PC) of a low intensity psychological intervention applied using Information and communication technologies (ICTs) for the treatment of multimorbidity in PC…
- Trial name
- NCT03426709
- Testing
- Low intensity Internet-delivered psychotherapy
- Where
- 4 sites in Spain
- Volunteers
- 196 people
- Sponsor
- Javier Garcia Campayo
Apnea of Prematurity
"Prapela® SVS Incubator Pad for Apnea of Prematurity
The study proposes to complete the development of and then establish the safety, efficacy, and clinical risk/benefit of a novel hospital incubator pad with stochastic vibrotactile stimulation (SVS) that will provide a…
- Trial name
- Prapela AOP (NCT06374147)
- Testing
- SVS mattress
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- Tufts Medical Center
Gallstones, Cholelithiasis
Chinese Registry Study on Treatment of Cholecysto-Choledocholithiasis
Patients with gallstone and confirmed common bile duct stones are registered in this study. The three managements for common bile duct stones are endoscopic sphincterotomy (EST), laparoscopic common bile duct exploration (LCBDE)…
- Conditions
- Gallstones, Cholelithiasis, Cholecystolithiasis, Choledocholithiasis
- Trial name
- CREST Choles (NCT02554097)
- Testing
- endoscopic sphincterotomy, laparoscopic common bile duct exploration, laparoscopic transcystic common bile duct exploration
- Where
- China
- Volunteers
- 2,700 people
- Sponsor
- Beijing Friendship Hospital
Skin Disease
Washing Without Water: Cost-effectiveness of a Rapidly Spreading Nursing Intervention in Bedridden Patients'
The purpose of this study is to compare the traditional bed bath with 'washing without water' on 1) effects on skin integrity 2) patient and nurse satisfaction and 3) costs.
- Trial name
- WWW (NCT01187732)
- Testing
- Washing without water
- Where
- Netherlands
- Volunteers
- 500 people
- Sponsor
- Betsie van Gaal
Schizophrenia, Schizotypal Disorder
The OPUS YOUNG Trial. Early Intervention Versus Treatment as Usual for Adolescents With First-episode Psychosis
The OPUS YOUNG (OY) study investigates the efficacy of early intervention service versus treatment as usual (TAU) for adolescents aged 12-17 years with a first-episode psychosis.
- Conditions
- Schizophrenia, Schizotypal Disorder, Delusional Disorder, Acute and Transient Psychotic Disorder, Unspecified
- Trial name
- OPUS-YOUNG (NCT04916626)
- Testing
- OPUS YOUNG, Treatment as Usual
- Where
- Denmark
- Volunteers
- 284 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Diabetes Mellitus, Type 2, Hypertension
Evaluation of the Chronic Disease Co-Care Pilot Scheme
The Chronic Disease Co-Care (CDCC) Pilot Scheme is initiated for early screening and management of people with hypertension (HT), pre-diabetes mellitus (pre-DM) and diabetes mellitus (DM) in Hong Kong.
- Conditions
- Diabetes Mellitus, Type 2, Hypertension, Chronic Disease, Disease Management
- Trial name
- NCT06310148
- Testing
- The Chronic Disease Co-Care (CDCC) Pilot Scheme
- Where
- Hong Kong
- Volunteers
- 3,772 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Cardiovascular Disease
Same Day Versus Next Day Discharge: Ambulatory Closure Device Percutaneous Intervention
This is a multi-center trial that will evaluate the safety, feasibility, and cost effectiveness of discharging patients, who have had successful percutaneous coronary intervention (PCI) and deployment of the AngiomaxTM closure…
- Trial name
- ABCD-PCI (NCT01230606)
- Testing
- discharge vs. overnight stay
- Where
- 2 sites in United States
- Volunteers
- 303 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Heart Failure
Trial of Education and Compliance in Heart Dysfunction (TEACH)
The emphasis of this grant is to investigate ways to educate patients, not only to improve their knowledge about medications and diet that are important for better outcomes in heart failure, but also to try to understand how…
- Trial name
- NCT00211289
- Testing
- Education by community pharmacist
- Where
- 2 sites in Canada
- Volunteers
- 383 people
- Sponsor
- London Health Sciences Centre
Rheumatoid Arthritis
Optimal Management of Rheumatoid Arthritis Patients Requiring Biologic Therapy
That anti-TNF therapy and rituximab therapy are equally effective in treating patients with rheumatoid arthritis who meet the eligibility criteria for biologic therapy in the British Society for Rheumatology guidelines, and have…
- Trial name
- ORBIT (NCT01021735)
- Testing
- etanercept or adalimumab, Rituximab
- Where
- 8 sites in United Kingdom
- Volunteers
- 302 people
- Sponsor
- University of Glasgow
Ulcerative Colitis, Crohn Disease
A Multicentered Prospective Cohort Study of Chinese IBD Patients
Inflammatory bowel disease(IBD), including ulcerative colitis (UC) and Crohn's disease (CD), is characterized by chronic and recurrent nonspecific intestinal inflammation with high disability rate.
- Trial name
- NCT05386290
- Testing
- Infliximab, Vedolizumab, Ustekinumab
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking Union Medical College Hospital
Moderate Acute Malnutrition
Comparison of Four Different Supplementary Foods in the Treatment of Moderate Acute Malnutrition
The research seeks to determine the relative effectiveness and cost effectiveness of alternative supplementary foods in the treatment of moderate acute malnutrition (MAM) in normal program settings.
- Trial name
- NCT03146897
- Testing
- Supplementary Food
- Where
- Sierra Leone
- Volunteers
- 2,691 people
- Sponsor
- Tufts University
Irreversible Pulpitis, Anesthesia, Local
Cost-Effectiveness of Upfront Supplemental Anaesthesia in Symptomatic Irreversible Pulpitis
The goal of this clinical trial is to learn whether giving extra (supplemental) local anaesthetic injections at the start of treatment, rather than only after the standard injection fails, makes numbing of painful lower molar…
- Trial name
- UPFRONT-SIP (NCT07907120)
- Testing
- Inferior Alveolar Nerve Block With 2% Lidocaine With 1:80,000 Adrenaline, Upfront Buccal Infiltration With 4% Articaine With 1:100,000 Adrenaline, Upfront Intraligamentary Injection With 2% Lidocaine With 1:80,000 Adrenaline
- Where
- India
- Volunteers
- 234 people
- Sponsor
- Jamia Millia Islamia
Malaria
Evaluation of the Public Health Impact of Seasonal Intermittent Preventive Treatment (IPT) in Children in Senegal
In areas of seasonal malaria transmission the burden of severe disease and mortality due to malaria is mainly among children under 5 years of age.
- Trial name
- NCT00712374
- Testing
- sulfadoxine-pyrimethamine plus amodiaquine
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Postoperative Nausea and Vomiting
Implementation Study of the PostOperative Nausea and Vomiting Prediction Rule
This study evaluates whether the implementation of a prediction rule for postoperative nausea and vomiting changes physician behaviour, improves patient outcome and improves cost-effectiveness of treatment of postoperative nausea…
- Trial name
- NCT00293618
- Testing
- Automatic Risk Presentation in the operating room, Education, Feedback
- Where
- Netherlands
- Volunteers
- 11,970 people
- Sponsor
- UMC Utrecht
Health, Subjective, Cost Effectiveness
Effects of Patient-centered Telephone Education in Day Surgery
This study describe and evaluate the effectiveness of patient-centered telephone education in day surgery. The aim is to evaluate the effects of patient-centered telephone education on the experienced health of adult patients and…
- Trial name
- NCT03549403
- Testing
- Patient-centered telephone education
- Where
- Finland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Polypectomy
Study on Complications, EfficAcy and Costs of Large Polypectomy
Colonoscopy has been shown to reduce the incidence and mortality of colorectal cancer, through the recognition and removal of pre-cancerous lesions, which in most cases evolve with a sequence that goes through formation of…
- Trial name
- SCALP (NCT02694120)
- Volunteers
- 1,000 people
- Sponsor
- Valduce Hospital
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