Clinical trials: Cost-Effectiveness
Carious Primary Molars
Clinical And Cost- Effectiveness of Allium Sativum Oil (Garlic Oil ) Versus Mineral Trioxide Aggregate in Primary Molars Pulpotomy in Group of Egyptian Children : A Randomised Clinical Pilot Study.
Allium Sativum oil is advocated to prove the capability of new natural products in replacing higher cost pharmacological materials, while achieving the same successful clinical and radiographic long-term results.
- Trial name
- NCT04903808
- Testing
- Allium Sativum Oil, Mineral Tri-Oxide Aggregate
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Schizophrenia
Observational Study to Assess Outcomes During Antipsychotic Treatment With Paliperidone ER or Other Oral Antipsychotics
The purpose of this non-interventional, observational and international registry study is to document the prescribing patterns in daily clinical practice and to assess long term treatment outcomes related to initiation of…
- Trial name
- PILAR (NCT00696813)
- Where
- 84 sites in Canada, Czechia and 5 more
- Volunteers
- 3,064 people
- Sponsor
- Janssen-Cilag International NV
PreDiabetes, Hyperglycemia
Effectiveness and Cost-Effectiveness of Fully-Automated Digital vs. Human Coach-Based Diabetes Prevention Programs
The purpose of this research study is to compare the effectiveness of a fully automated digital diabetes prevention program to standard of care human coach-based diabetes prevention programs for promoting clinically meaningful…
- Conditions
- PreDiabetes, Hyperglycemia, Glucose, High Blood, Overweight
- Trial name
- NCT05056376
- Testing
- Digital Diabetes Prevention Program (dDPP), Human Coach-based Diabetes Prevention Program (hDPP)
- Where
- 2 sites in United States
- Volunteers
- 368 people
- Sponsor
- Johns Hopkins University
Medication Initiation for Long-term Conditions
Implementation of a New Model of Care for Supporting Long-term Medication Adherence (Phase A)
The overall objective of the myCare Start-I project is to adapt, implement and evaluate the myCare Start service within the Swiss pharmacy-physician network to enhance medication adherence during the initiation of a new long-term…
- Trial name
- myCareStart-I (NCT06191835)
- Testing
- myCare Start
- Where
- 2 sites in Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Geneva, Switzerland
Critical Illness
Cost Effectiveness Analysis of Critical Care in Resource Limited Setting
The purpose of this study was to examine the cost effectiveness of critical care in a middle income country with limited resources. The main study hypothesis was that critical care is cost effective in low resources setting.
- Trial name
- CEACCLR (NCT02556476)
- Testing
- mechanical ventilation, neuromuscular blockade, renal replacement therapy
- Volunteers
- 148 people
- Sponsor
- University of Sarajevo
Skin Cancer
Using Technology to Scale-Up an Occupational Sun Protection Policy Program
Comprehensive approaches that combine sun protection policy and education for outdoor workers can reduce their risk for skin cancer by reducing their exposure to solar ultraviolet radiation on the job.
- Trial name
- SSW-T (NCT03278340)
- Testing
- Sun Safe Workplaces - Technology, Sun Safe Workplaces -In Person
- Where
- 2 sites in United States
- Volunteers
- 2,644 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Cardiovascular Disease
Technology-enabled Cardiac Rehabilitation Through PATHway. Feasibility, Clinical Effectiveness and Cost-effectiveness
The PATHway system is designed to help patients remain physically active and maintain a good cardiovascular health. It proposes a novel approach that aims to empower patients to self-manage their CVD, set within a collaborative…
- Trial name
- PATHway (NCT02717806)
- Testing
- PATHway
- Where
- 3 sites in Belgium, Ireland
- Volunteers
- 120 people
- Sponsor
- KU Leuven
Cost Effectiveness, Exposure to Radiofrequency
Cost-effectiveness of RFA vs. PEI for Early-stage HCC
Introduction: Liver transplantation(LT) is the gold-standard treatment for unresectable early-stage HCC within the Milan criteria. However, long waiting time can lead to dropout from LT candidacy.
- Trial name
- NCT06450613
- Testing
- radiofrequency ablation, percutaneous ethanol injection
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Hospital Israelita Albert Einstein
Hydrocephalus, Ventriculoperitoneal Shunt Infection
Efficacy and Cost-Effectiveness of Topical Vancomycin Powder in Preventing Pediatric Ventriculoperitoneal Shunt Infections Across Different Etiologies
Objectives Primary: To measure the reduction in VP shunt infection rates using topical vancomycin powder. Secondary: To compare efficacy across different Etiological Strata (Congenital, Post-hemorrhagic, post-inflammatory).
- Conditions
- Hydrocephalus, Ventriculoperitoneal Shunt Infection, Surgical Site Infection (SSI), Cerebrospinal Fluid Shunt Infection
- Trial name
- NCT07547826
- Testing
- Topical Vancomycin Powder, Standard Perioperative Care
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Assiut University
Cost Effectiveness
Cost-Effectiveness Study on Establishing a Warfarin Counseling Clinic for Egyptian Patients With Mitral Valve Prostheses
The outcome of poor adherence to medications can be life threatening with certain drugs like warfarin. For each 10% increase in non-adherence to warfarin, there was a 14% increase in the risk of under-anticoagulation with…
- Trial name
- NCT04409613
- Testing
- Education and counseling
- Where
- Egypt
- Volunteers
- 59 people
- Sponsor
- Ain Shams University
Coronary Artery Disease
Role of Cardiac CT in Rapid Access Chest Pain Clinics (RADICAL)
Heart disease remains the most common cause of death in the UK. Chest pain is often the first presenting symptom in patients with heart disease, and may be a warning signal prior to a heart attack or death.
- Trial name
- RADICAL (NCT01464203)
- Testing
- CT coronary angiography, Standard of Care
- Where
- 3 sites in United Kingdom
- Volunteers
- 600 people
- Sponsor
- AJAY YERRAMASU
Bipolar Disorder
Cost- Effectiveness and Quality of Life Assessment in Bipolar Disorder Depressive Episode
To evaluate the effectiveness of an algorithm for Bipolar Disorder depressive episodes (BDD) using medications available in the Brazilian Public Healthcare System (SUS).
- Trial name
- NCT02918097
- Testing
- Lithium Carbonate, Sertraline, Nortriptyline
- Volunteers
- 78 people
- Sponsor
- Federal University of Rio Grande do Sul
Dizziness
A Trial of Booklet Based Self Management of Dizziness
The investigators primary aim is to test whether or not provision of the self-help booklet teaching VR exercises, with up to one hour of telephone support from a vestibular therapist, will be more effective than routine care in…
- Trial name
- NCT00732797
- Testing
- Self-treatment booklet, Remote telephone support
- Where
- United Kingdom
- Volunteers
- 337 people
- Sponsor
- University of Southampton
Schizoaffective Disorder, Schizophrenia
To Determine if Olanzapine is More Cost Effective Than Haloperidol for the Treatment of Schizophrenia
Although currently marketed antipsychotic drugs are useful in the treatment of schizophrenia, efficacy and safety profiles need to be improved.
- Trial name
- NCT00007774
- Testing
- Haloperidol, Olanzapine
- Where
- 18 sites in United States
- Volunteers
- 600 people
- Sponsor
- US Department of Veterans Affairs
Clinical Trial
Raising Healthy Children: A Hybrid Trial of the Family Check-Up 4 Health in Primary Care
This study is a hybrid implementation-effectiveness trial of the Family Check-Up 4 Health (FCU4Health), an adapted version of the Family Check-Up, in pediatric primary care.
- Trial name
- FCU4Health (NCT03013309)
- Testing
- Family Check-Up 4 Health, Treatment as usual
- Where
- 3 sites in United States
- Volunteers
- 240 people
- Sponsor
- Arizona State University
Coronary Artery Disease
Coronary Computed Tomographic Angiography for Selective Cardiac Catheterization
To determine the effectiveness, safety, and cost efficiency associated with a CCTA-guided selective catheterization strategy for stable patients but without known CAD and an American Heart Association/ American College of…
- Trial name
- CONSERVE (NCT01810198)
- Testing
- Cardiac CT, Invasive Coronary Angiography
- Where
- 13 sites in United States, Brazil and 4 more
- Volunteers
- 1,631 people
- Sponsor
- MDDX LLC
Insomnia
Implementation of CBT-I in Cancer Clinics
Insomnia affects 30-60% of cancer patients, thus making it one of the most common disturbances in this population. When untreated, which is the rule rather than the exception, insomnia often becomes chronic.
- Trial name
- NCT04817163
- Testing
- Web-based cognitive-behavioral therapy for insomnia (CBT-I), Professionally-administered booster face-to-face CBT-I sessions
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- CHU de Quebec-Universite Laval
Tuberculosis (TB)
Pharmacist-led Digital Interventions to Improve Tuberculosis Treatment Adherence
The gold standard for tuberculosis (TB) treatment support requires directly observed therapy (DOT), which means a trained health worker observes the patient swallow each dose of medication every day for 2 months.
- Trial name
- CARE-TB (NCT07069387)
- Testing
- CARE-TB digital adherence package, Standard Care
- Where
- Malaysia
- Volunteers
- 81 people
- Sponsor
- University of Malaya
Schizophrenia
Cost-utility Study of a Group of Compensatory Cognitive Remediation in Schizophrenia
Significant cognitive impairment (executive functions, memory, attention) is common in schizophrenia affecting up to 80% of patients.
- Trial name
- Grecco (NCT02879604)
- Testing
- Compensatory cognitive training, Usual
- Where
- 9 sites in France
- Volunteers
- 218 people
- Sponsor
- University Hospital, Montpellier
Coronary Artery Bypass, Anesthesia
Sustainable Anesthesia in Myocardial Revascularization Surgery.
Introduction: Greenhouse gases threaten the health and safety of humanity. The Declaration of Helsinki seeks to protect human health and emphasizes the urgency of implementing sustainable strategies.
- Conditions
- Coronary Artery Bypass, Anesthesia, Sustainability
- Trial name
- NCT07508865
- Testing
- Optimized recovery, Standard Anesthetic Practice
- Where
- Chile
- Volunteers
- 116 people
- Sponsor
- Universidad de La Frontera
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