Clinical trials: Cost-effectiveness
Type 1 Diabetes
Use of Continuous Glucose Monitoring Devices Among People Living With Type 1 Diabetes in South Africa
Diabetes mellitus (diabetes) is a chronic condition that represents a major public health and clinical concern. Self-monitoring of blood glucose (SMBG) is a critical part of the care of individuals with diabetes.
- Trial name
- ACCEDE (NCT05944718)
- Testing
- Continuous glucose monitor
- Where
- 3 sites in South Africa
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Lifestyle Intervention, Lifestyle Risk Reduction
Lifestyle Intervention in the Memory Clinics of General and Academic Hospitals Trial
Lifestyle Intervention in the memory clinics of General and academic Hospitals Trial (LIGHT) is a multi-center, randomized, controlled, lifestyle intervention trial among 300 older adults (≥50 years) with subjective cognitive…
- Conditions
- Lifestyle Intervention, Lifestyle Risk Reduction, Cognitive Decline, Dementia
- Trial name
- LIGHT (NCT06832761)
- Testing
- Personalized lifestyle intervention
- Where
- 2 sites in Netherlands
- Volunteers
- 300 people
- Sponsor
- Maastricht University Medical Center
Endometriosis, Rectum, Endometriosis of Colon
The (Cost-)Effectiveness of Surgical Excision of Colorectal Endometriosis Compared to ART Treatment Trajectory
To goal of this study is to determine whether laparoscopic resection of colorectal endometriosis results in an increased cumulative live birth rate (CLBR) both spontaneous and after ART (including in vitro fertilization (IVF) or…
- Conditions
- Endometriosis, Rectum, Endometriosis of Colon, Subfertility, Female
- Trial name
- TOSCA (NCT05677269)
- Testing
- Laparoscopic excision of endometriosis, including colorectal endometriosis, In vitro fertilisation or intracytoplasmic sperm injection
- Where
- 10 sites in Netherlands
- Volunteers
- 339 people
- Sponsor
- Leiden University Medical Center
Chronic Obstructive Pulmonary Disease, Asthma
Effectiveness and Implementation of the Assessment of Burden of Chronic Conditions (ABCC)-Tool
This study is designed to evaluate the effectiveness and implementation of the Assessment of Burden of Chronic Conditions (ABCC)-tool for patients with COPD, asthma, diabetes mellitus type 2 or heart failure (and any combination…
- Conditions
- Chronic Obstructive Pulmonary Disease, Asthma, Diabetes Mellitus, Type 2, Heart Failure
- Trial name
- NCT04127383
- Testing
- Assessment of Burden of Chronic Conditions (ABCC)-tool
- Where
- Netherlands
- Volunteers
- 237 people
- Sponsor
- Maastricht University
Skin Cancer
Using Technology to Scale-Up an Occupational Sun Protection Policy Program
Comprehensive approaches that combine sun protection policy and education for outdoor workers can reduce their risk for skin cancer by reducing their exposure to solar ultraviolet radiation on the job.
- Trial name
- SSW-T (NCT03278340)
- Testing
- Sun Safe Workplaces - Technology, Sun Safe Workplaces -In Person
- Where
- 2 sites in United States
- Volunteers
- 2,644 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Myopia, Hyperopia
Evaluation of Effectiveness of Correcting Refractive Error With Ready-made Spectacles
This research project will compare two methods of correcting refractive error (long or short-sightedness) with spectacle lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- RECS (NCT00657670)
- Testing
- Ready-made spectacles, Spectacles
- Where
- 2 sites in China, India
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Frail Elderly
Effectiveness of a Health Education Program in a Primary Care Setting
This study was designed to assess the effectiveness of a Health Education Program (HEP) for improving the well-being and reducing the health care use and cost of care of frail older outpatient veterans, and for improving the…
- Trial name
- NCT00012779
- Testing
- Health Education Program
- Where
- 3 sites in United States
- Volunteers
- 288 people
- Sponsor
- US Department of Veterans Affairs
Pulmonary Disease, Chronic Obstructive, COPD
eRT Remote Health Monitoring
Remote Health Monitoring (RHM) is the assessment of one's own symptoms at home between doctor visits, using things like at-home breathing tests, electronic diaries to answer questionnaires, and other monitoring devices.
- Conditions
- Pulmonary Disease, Chronic Obstructive, COPD, Chronic Obstructive Lung Disease, Bronchitis, Chronic
- Trial name
- NCT01495780
- Testing
- Remote Health Monitoring
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of California, Los Angeles
Post Traumatic Stress Disorder
Intensive Treatment Versus Standard Weekly Prolonged Exposure for Adults With Post-Traumatic Stress Disorder
The goal of this clinical trial is to compare a novel, massed treatment format of prolonged exposure to gold standard trauma focused cognitive behavioral therapy (weekly delivered prolonged exposure) for post-traumatic stress…
- Trial name
- NCT05934175
- Testing
- Intensive treatment with prolonged exposure, Weekly delivered prolonged exposure
- Where
- Sweden
- Volunteers
- 140 people
- Sponsor
- Karolinska Institutet
Thrombocytopaenia
Meta-analysis - Eltrombopag
The purpose of the meta-analysis was to explore the efficacy of eltrombopag versus placebo (standard of care)
- Trial name
- NCT01235988
- Testing
- Eltrombopag
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
Pregnancy Related, Fertility Issues
Luteal Phase Support in IUI MOH Treatment Luteal Phase Support in IUI MOH Treatment
The LUMO study is a multicenter, randomized controlled trial that evaluates the effectivity of luteal phase support in MOH/IUI treatment.
- Conditions
- Pregnancy Related, Fertility Issues, Luteal Phase Defect, Infertility Unexplained
- Trial name
- LUMO (NCT05080569)
- Testing
- Progesterone Vaginal Product
- Where
- Netherlands
- Volunteers
- 1,008 people
- Sponsor
- UMC Utrecht
Endoscopic Submucosal Dissection, Early Gastric Cancer
Efficacy and Safety Study of Endoscopic Submucosal Dissection for Early Gastric Cancer
The purpose of this study is to evaluate the safety and clinical effectiveness of ESD(Endoscopic Submucosal Dissection) for early gastric cancer analyzing short-term and long-term results of endoscopic treatment.
- Conditions
- Endoscopic Submucosal Dissection, Early Gastric Cancer, Multi-center, Single-arm Clinical Trial, Historical Control Group
- Trial name
- ESD (NCT01132469)
- Testing
- Endoscopic Submucosal Dissection
- Where
- South Korea
- Volunteers
- 1,158 people
- Sponsor
- National Evidence-Based Healthcare Collaborating Agency
Head and Neck Cancer
Efficacy of Prophylactic Treatment With Antibiotics During Concomitant Chemoradiotherapy in Patients With Head and Neck Cancer to Prevent Aspiration Pneumonia
Patients with locally advanced head and neck cancer treated with chemo-radiotherapy have (during and shortly after this treatment) a high risk of developing pneumonia by aspiration.
- Trial name
- PANTAP (NCT01598402)
- Testing
- amoxicillin/clavulanic acid suspension
- Where
- 6 sites in Netherlands
- Volunteers
- 106 people
- Sponsor
- Radboud University Medical Center
Chronic Pain, Low Back Pain
Cost-Effectiveness Analysis of a Virtual Reality-Assisted Hypnotherapy Program on Quality of Life in Patients with Chronic Low Back Pain: a Multicenter, Randomized, Prospective, Comparative, Open-Label, Parallel-Group Study
This randomized, prospective study aims to evaluate the effectiveness and cost-efficiency of a Virtual Reality (VR)-assisted hypnotherapy program on quality of life in patients with chronic low back pain.
- Conditions
- Chronic Pain, Low Back Pain, Chronic Low Back Pain (CLBP)
- Trial name
- NCT06698354
- Testing
- Virtual Reality-Assisted Hypnotherapy, Standard Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- University of Beykent
Diarrhea
Safety, Efficacy and Cost-effectiveness of Racecadotril in Children With Acute Diarrhea in Mexico
Rationale: Acute diarrhea (AD) is still a significant morbidity-mortality problem worldwide. Although oral rehydration therapy is the cornerstone, its anti-diarrheal effect is a controversial subject.
- Trial name
- Raceca-Mex (NCT01153854)
- Testing
- Racecadotril
- Where
- Mexico
- Volunteers
- 454 people
- Sponsor
- National Institute of Pediatrics, Mexico
Asthma
Effectiveness of the Propeller Health (Formerly Asthmapolis) Monitoring System
Propeller Health is collaborating with Dignity Health (formerly Catholic Healthcare West (CHW)) to carry out a focused demonstration project to evaluate the effectiveness and potential cost savings of a deployment of the…
- Trial name
- NCT01509183
- Testing
- Propeller Health System (formerly Asthmapolis System)
- Where
- United States
- Volunteers
- 495 people
- Sponsor
- Reciprocal Labs
Heart Failure, Asthma
Economic Evaluation of Heart Failure Management in Colombian Clinics
Cost effectiveness analysis of local management of patients diagnosed with heart failure disease compared with an ideal guideline-based management.
- Trial name
- EconoHeart (NCT01084564)
- Volunteers
- 300 people
- Sponsor
- AstraZeneca
Breast Neoplasms, Musculoskeletal Pain
Hypnosis to Reduce Aromatase Inhibitor Pain and Improve Adherence
The purpose of this study is to determine whether hypnosis is efficacious in reducing musculoskeletal pain in breast cancer survivors taking aromatase inhibitors, and by doing so, whether hypnosis can help survivors to be more…
- Trial name
- NCT02657993
- Testing
- Hypnosis, Attention Control
- Where
- United States
- Volunteers
- 191 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Stenoses, Spinal
Cost-effectiveness of Small Size Interarcuair Decompression Versus Extended Decompression in Patients With Intermittent Neurogenic Claudication
Rationale: Minimally invasive techniques have gained popularity to decompress lumbar spinal stenosis in the elderly. However, high quality evidence based on randomised controlled trials are not available.
- Trial name
- Size (NCT03480893)
- Testing
- small size interarcuair decompression, Laminectomy
- Where
- Netherlands
- Volunteers
- 174 people
- Sponsor
- Erasmus Medical Center
Competencies of Midwives, Cost-benefit Analysis of Modular Training
Effect of Skill Birth Attendant Training to Improve the Competency of Service Providers
This clinical trial's primary goal is to compare birth attendants' competencies. It aims to answer the questions: Does the new modular training package enhance the competencies of skilled birth attendants? Does the competencies…
- Trial name
- NCT05866016
- Testing
- Skill birth attendant training
- Where
- 2 sites in Nepal
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ministry of Health Gandaki Province, Nepal