Clinical trials: Covid-19 Infection
COVID-19 Pandemic
Fourth BNT162b2 COVID-19 Vaccine Dose
The Omicron variant of concern (VOC) is currently rapidly spreading worldwide, with extremely high transmission rates, with an estimated R of >3.
- Trial name
- NCT05231005
- Testing
- BNT162b2 vaccine
- Where
- Israel
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Hematologic Malignancy
Outcomes of Critically Ill Patients With Hematologic Malignancies
The investigators sought to report the outcomes of patients with haematological malignancies admitted to the intensive care units and to define pre-intensive care units prognostic factors for in-hospital all-cause mortality.
- Trial name
- NCT06410066
- Testing
- no intervention
- Volunteers
- 144 people
- Sponsor
- Soroka University Medical Center
Vaccine Hesitancy
Motivational Interviewing for Vaccine Uptake in Latinx Adults
The goal of this clinical trial is to test whether modified behavioral health services, integrating motivational interviewing, will reduce vaccine hesitancy and increase uptake for the COVID-19 and influenza vaccines among Latinx…
- Trial name
- MIVacuna (NCT06062056)
- Testing
- EHR alert, Motivational Interviewing, Warm hand off to nurse
- Where
- 2 sites in United States
- Volunteers
- 3,698 people, healthy volunteers welcome
- Sponsor
- Boston College
Covid19
COVID-19 Supplemental Vaccine Boost to Enhance T Cell Protection in Those Who Have Already Received EUA S-Based Vaccines
This is a phase 1/2 study in adult healthy subjects that have previously been vaccinated with an FDA-authorized vaccine against COVID-19.
- Trial name
- NCT04843722
- Testing
- hAd5-S-Fusion+N-ETSD vaccine
- Volunteers
- healthy volunteers welcome
- Sponsor
- ImmunityBio, Inc.
Rheumatic Diseases
Coronaphobia in Rheumatic Diseases
COVID-19 is a contagious respiratory disease that is caused Severe Acute Respiratory Syndrome causing Coronavirus-2 (SARS-CoV-2). The most common symptoms are fever, cough and dyspnoea.
- Trial name
- NCT05554029
- Testing
- Coronaphobia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
COVID19 Infection
Clinical Trial to Assess Efficacy of cYclosporine Plus Standard of Care in Hospitalized Patients With COVID19
The study hypothesis is that cyclosporine, added to standard treatment of hospitalized patients with COVID19 infection may improve their prognosis.
- Trial name
- NCT04392531
- Testing
- Cyclosporine, Standard treatment
- Where
- 7 sites in Spain
- Volunteers
- 111 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Sperm Preservation in Oncological Patients, Fertility
Presence of SARS-CoV-2 (COVID-19) in Semen: Impact on Fertility Preservation in Male Oncological Patients ?
During the COVID-19 pandemic, the French Agency of Biomedicine has recommended maintaining fertility preservation for patients requiring immediate oncological treatments exhibiting gonadotoxic effects.
- Conditions
- Sperm Preservation in Oncological Patients, Fertility, Cryopreservation
- Trial name
- FERTICOVID (NCT04487639)
- Testing
- SARS-CoV-2 research in nasopharyngeal swab, sperm and serologics
- Where
- 16 sites in France
- Volunteers
- 129 people
- Sponsor
- University Hospital, Clermont-Ferrand
Long Covid19, Pulmonary Rehabilitation
Combined Pulmonary Rehabilitation and PMR for Long-Term COVID-19 Symptoms: A RCT
Our study aimed to evaluate the effectiveness of a 21-day program combining pulmonary rehabilitation (PR) with progressive muscle relaxation (PMR) in patients experiencing long-term symptoms of COVID-19.
- Conditions
- Long Covid19, Pulmonary Rehabilitation, Progressive Muscle Relaxation
- Trial name
- NCT06492577
- Testing
- Pulmonary rehabilitation protocol, Progressive muscle relaxation protocol
- Where
- Romania
- Volunteers
- 61 people
- Sponsor
- Spitalul Clinic de Boli Infecțioase și Pneumoftiziologie Dr. Victor Babeș Timișoara
COVID-19
Sirolimus Treatment in Hospitalized Patients With COVID-19 Pneumonia
The main objective of our study is to determine if treatment with sirolimus can improve clinical outcomes in hospitalized patients with COVID-19.
- Trial name
- SCOPE (NCT04341675)
- Testing
- Sirolimus
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- University of Cincinnati
COVID-19 Pneumonia, Virus Diseases
Investigation of Efficacy and Safety of Electrical Signal Therapy Provided by Dr Biolyse® Device in COVID-19 Disease
Dr. Biolyse® is a device with artificial intelligence that works in sync with the immune system and can be integrated like an element of this system. It is designed to develop chemical immunity within the body against infections.
- Conditions
- COVID-19 Pneumonia, Virus Diseases, COVID-19
- Trial name
- DoBiC-19 (NCT06113757)
- Testing
- Signal Therapy provided by Dr.Biolyse device, Liquid Support Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- AVB Biotechnology
Rheumatic Diseases, COVID-19 Vaccine
Vaccine Hesitancy in Black/African Americans With Rheumatic Diseases
To establish the efficacy of a community-based POL (Popular Opinion Leader) intervention with two different trainings designed to increase COVID-19 vaccine and booster uptake and reduce hesitancy among social networks of Black…
- Conditions
- Rheumatic Diseases, COVID-19 Vaccine, COVID-19, SLE
- Trial name
- NCT05822219
- Testing
- COVID-19 vaccine and booster training, and importance
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Disordered Eating, Stress
Biofeedback for CHAMPS
As a result of the COVID-19 pandemic, the degree of burnout and consequential negative psychological effects experienced by healthcare providers has been substantially exacerbated.
- Trial name
- NCT04921228
- Testing
- Heart rate variability biofeedback
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Villanova University
COVID-19
The Evaluation of Hemostasis in Hospitalized COVID-19 Patients
Coronavirus disease 2019 (COVID-19), a viral respiratory illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been shown to predispose patients to thrombotic diseases (venous and arterial) with…
- Trial name
- TARGET-COVID (NCT04493307)
- Testing
- Phlebotomy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- LifeBridge Health
Immune Response Post Covid 19 Vaccination
Immune Response of Haemodialysis Patients Post Covid-19 Vaccination
The purpose of this study is to assess immune response of end stage renal failure patients after Covid 19 vaccination
- Trial name
- Covid-19 (NCT04872751)
- Where
- Malaysia
- Volunteers
- 425 people
- Sponsor
- Penang Hospital, Malaysia
Systemic Nickel Allergic Syndrome
Telemedicine for SNAS Patients in COVID-19 Pandemic
Restrictions due to Covid-19 pandemic have brought negative social and psychological consequences on people and limited patients' access to hospital care.
- Trial name
- DISTANCE (NCT04894331)
- Testing
- Dietary intervention, Video call
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Catholic University of the Sacred Heart
COVID-19
FLARE: Favipiravir +/- Lopinavir: A RCT of Early Antivirals
The current pandemic of SARS-CoV-2 causing COVID-19 disease is an unprecedented global emergency. COVID-19 appears to be a disease with an early phase where the virus replicates, coinciding with first presentation of symptoms…
- Trial name
- FLARE (NCT04499677)
- Testing
- Favipiravir, Lopinavir/ Ritonavir
- Where
- 2 sites in United Kingdom
- Volunteers
- 240 people
- Sponsor
- University College, London
Influenza, RSV
Surveillance, Assessment and Detection of Influenza Associated Respiratory Infections in HIV Positive and Negative Individual in Lusaka, Zambia.
Background and rationale:The World Health Organisation (WHO), estimates influenza global deaths at 290,000 to 650,000 annually. Although influenza is mostly associated with upper respiratory tract infections (URTIs), its role in…
- Conditions
- Influenza, RSV, COVID - 19
- Trial name
- NCT07030075
- Where
- 2 sites in Zambia
- Volunteers
- 594 people
- Sponsor
- Centre for Infectious Disease Research in Zambia
Cardiovascular Diseases
Effects of COVID-19 Pandemic on a Health Care System: Case Study of the CirculatORy System in LiThuania
Coronavirus disease of 2019 (COVID-19) affected the health care systems all around the world. The collateral damage of the pandemic on the cardiovascular (CV) care and CV mortality has been noticed and reported early.
- Trial name
- COVID-COR-LT (NCT05021575)
- Testing
- Data collection on outpatient care, Data collection on hospitalisation, Data collection on cardiovascular mortality
- Where
- 3 sites in Lithuania
- Volunteers
- 839,678 people
- Sponsor
- Vilnius University
COVID-19 Pneumonia, Hypoxemia
Hepatitis B Virus Reactivation in COVID-19
The aim of this observational cohort study was to evaluate adherence to hepatitis B virus (HBV) screening guidelines in a country characterized by low HBV prevalence and assess the potential reactivation and progression of HBV…
- Conditions
- COVID-19 Pneumonia, Hypoxemia, Hepatitis B
- Trial name
- HBV-C19 (NCT07154212)
- Testing
- Hepatitis B virus infection
- Where
- Slovenia
- Volunteers
- 1,793 people
- Sponsor
- University Medical Centre Ljubljana
ARDS, Human
AllogeneiC Expanded Human MSC Therapy in Patients Recovering From COVID-19 Acute Respiratory Distress Trial
Allogeneic culture-expanded bone marrow-derived human mesenchymal stem cells (MSC) are the subject of the current study as they are supported by preclinical and clinical data for potential to provide a safe and effective…
- Trial name
- ACE_CARD (NCT05491681)
- Testing
- intravenous delivery of allogeneic bone marrow-derived MSCs
- Sponsor
- BioCardia, Inc.