Clinical trials: Covid19, completed
COVID-19
Reduction in COVID-19 Infection Using Surgical Facial Masks Outside the Healthcare System
In the current COVID-19 pandemic with coronavirus, SARS-COV2, the Danish Health Authorities recommend using facial masks in the health care system when handling patients presumed or proven to be infected with the virus.
- Trial name
- NCT04337541
- Testing
- Surgical facial mask
- Where
- Denmark
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Covid19
Clinical Efficacy of Heparin and Tocilizumab in Patients With Severe COVID-19 Infection
The COVID-19 infection primarily manifests itself as a respiratory tract infection, although new evidence indicates that this disease has systemic involvement involving multiple systems including the cardiovascular, respiratory…
- Trial name
- HEPMAB (NCT04600141)
- Testing
- Tocilizumab, Heparin - Therapeutic dosage, Heparin - Prophylactic dosage
- Where
- 3 sites in Brazil
- Volunteers
- 308 people
- Sponsor
- University of Sao Paulo
SARS-CoV-2 (Covid19)
Safety and Efficacy of Trans Sodium Crocetinate (TSC) in SARS-CoV-2 (COVID-19) Infected Subjects
This study will assess the safety and efficacy of TSC as a treatment for participants who are infected with SARS-CoV-2 (COVID-19).
- Trial name
- NCT04573322
- Testing
- Trans Sodium Crocetinate, Normal saline
- Where
- Romania
- Volunteers
- 25 people
- Sponsor
- Diffusion Pharmaceuticals Inc
Consent
Surgical Consent During the COVID-19 Pandemic
Multiloop audit of consenting practice in surgical procedures during the COVID-19 pandemic
- Trial name
- NCT04556604
- Testing
- Educational meetings and visual prompts
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medway Primary Care Trust
Obesity
Pharmacokinetics of Dexamethasone in COVID-19 Obese Patients
In this regard, the present research project aims to compare dexamethasone PK in normal-weight versus obese patients treated for COVID-19.
- Trial name
- CoDEX (NCT04996784)
- Testing
- Capillary blood sampling
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Jules Desmeules
Olfactory Disorder, Olfaction Disorders
Intranasal Injection of PRP Versus Saline for Treatment of Olfactory Dysfunction
This randomized clinical trial will evaluate the benefit of platelet-rich plasma (PrP) in the treatment of olfactory dysfunction.
- Conditions
- Olfactory Disorder, Olfaction Disorders, Olfactory Nerve Injuries, Olfactory Nerve Disorder
- Trial name
- NCT04406584
- Testing
- Injection into olfactory cleft
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Long COVID, Long COVID-19
RECOVER-NEURO: Platform Protocol to Measure the Effects of Cognitive Dysfunction Interventions on Long COVID Symptoms
This platform protocol is designed to be flexible so that it is suitable for a wide range of settings within health care systems, for remote settings, and in community settings where it can be integrated into COVID-19 programs…
- Conditions
- Long COVID, Long COVID-19, Long COVID19
- Trial name
- NCT05965752
- Testing
- BrainHQ/Active Comparator Activity, BrainHQ, PASC CoRE
- Where
- 24 sites in United States
- Volunteers
- 328 people
- Sponsor
- Duke University
Covid-19
Octagam 10% Therapy in COVID-19 Patients With Severe Disease Progression
This is a randomized, double-blind, placebo-controlled, multicenter, Phase 3 study to evaluate if high-dose Octagam 10% therapy can stabilize or improve clinical status in patients with severe Coronavirus disease
- Trial name
- NCT04400058
- Testing
- Octagam 10%, Saline Solution
- Where
- 22 sites in United States, Russia and 1 more
- Volunteers
- 207 people
- Sponsor
- Octapharma
Antiphospholipid Syndrome, COVID-19 Infection
Prospective Observational Study to Evaluate a Possible Change in APS Antibody Profiles After COVID-19 Infection or Vaccination
Prospective observational study to evaluate a possible change in APS antibody profiles after COVID-19 infection or vaccination
- Conditions
- Antiphospholipid Syndrome, COVID-19 Infection, COVID-19 Vaccination
- Trial name
- APSantiCo (NCT05313048)
- Where
- Germany
- Volunteers
- 82 people
- Sponsor
- Cardioangiologisches Centrum Bethanien
COVID-19, Venous Thromboembolism
Clinical Trial of Dimolegin (DD217) in Prevention of Thrombotic Complications in Patients With COVID-19
Study purpose was to study the safety and efficacy of Dimolegin - DD217 as a drug for prevention of thrombotic complications compared to Clexane (enoxaparin sodium) - the standard therapy currently prescribed to patients…
- Trial name
- NCT05185804
- Testing
- Dimolegin, Clexane
- Where
- 6 sites in Russia
- Volunteers
- 399 people
- Sponsor
- PharmaDiall Ltd.
COVID-19 Recovery
ENO Breathe vs Usual Care in COVID-19 Recovery
A randomised clinical trial to assess the impact of an online singing, breathing and wellbeing programme (ENO Breathe) developed specifically for people recovering from COVID-19.
- Trial name
- SHIELD ENO (NCT04830033)
- Testing
- ENO Breathe group
- Where
- United Kingdom
- Volunteers
- 153 people
- Sponsor
- Imperial College London
COVID-19, Desaturation of Blood
Hyperbaric Oxygen Therapy Effect in COVID-19 RCT (HBOTCOVID19)
The 2019-20 coronavirus disease, caused by COVID-19, is an ongoing pandemic.So far, no specific treatment has proven efficacy. Recent case series reported the use of Hyperbaric Oxygen Therapy (HBOT) on 5 severe COVID-19 patients…
- Trial name
- HBOTCOVID19 (NCT04358926)
- Testing
- Hyperbaric oxygen therapy
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Assaf-Harofeh Medical Center
Long COVID, COVID Long-Haul
Cardiopulmonary Exercise Tests in Patients With Long COVID
The value of clinical cardiopulmonary exercise testing (CPET) within healthcare settings has been established in the last decade.
- Trial name
- PREPP-19 (NCT06394921)
- Testing
- 2 day cardiopulmonary exercise test
- Where
- 5 sites in United States, India and 1 more
- Volunteers
- 146 people
- Sponsor
- Sheffield Hallam University
COVID-19-Induced Parosmia
Stellate Ganglion Block for COVID-induced Parosmia
Chronic olfactory dysfunction, both hyposmia and parosmia, from the COVID-19 pandemic is a growing public health crisis with up to 1.2 million people in the United States affected.
- Trial name
- SGB (NCT06253806)
- Testing
- Stellate Ganglion Block
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Washington University School of Medicine
Long COVID
Examining the Function of Cs4 on Post-COVID-19 Disorders
Cordyceps is a medicinal Chinese medicine. The benefits of cordyceps-related therapeutic action have been studied due to its anti-inflammation and immunomodulation features.
- Trial name
- NCT06054438
- Testing
- Chinese medicine nutritional supplement Cs4
- Where
- China
- Volunteers
- 110 people
- Sponsor
- The University of Hong Kong
COVID-19
[14C] Study to Investigate the Mass Balance and Biotransformation of WPV01 in Healthy Adult Chinese Male Participants
This is a single-center, non-randomized, open-label, single-dose, Phase I clinical study to evaluate the mass balance and biotransformation, safety and tolerability of WPV01 in healthy adult chinese male participants following a…
- Trial name
- NCT07080658
- Testing
- [14C]-WPV01
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Westlake Pharmaceuticals (Hangzhou) Co., Ltd.
COVID 19, Depression
COVID-19 : Stress Within Hospital Workers
As of December 2019, the global pandemic of COVID-19 has spread rapidly throughout the world, putting healthcare staff at the frontline.
- Conditions
- COVID 19, Depression, Stress, Psychological, Burnout
- Trial name
- NCT05037214
- Where
- France
- Volunteers
- 779 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Covid19
Remote Video Consultation for Quality of Life Assessment in Patients Hospitalised After COVID-19 Infection
Around 90.000 patients have been hospitalised due to COVID-19 infection in France between March 1st and June 15th; 19% of those requiring intensive care.
- Trial name
- TELECOVID (NCT04714138)
- Where
- France
- Volunteers
- 157 people
- Sponsor
- Groupe Hospitalier du Havre
Cholangitis, Secondary Biliary, Cholangiocarcinoma
Advanced Endoscopy During COVID-19
In this study, investigators aim to explore the status of advanced endoscopy in different endoscopy units all over the world.
- Conditions
- Cholangitis, Secondary Biliary, Cholangiocarcinoma, Obstructive Jaundice, Pancreas Cancer
- Trial name
- NCT04385147
- Testing
- Endoscopic management according to standard of care
- Where
- 5 sites in United States, Egypt and 3 more
- Volunteers
- 670 people
- Sponsor
- Al-Azhar University
Post-Viral Fatigue Syndrome
Low-dose Naltrexone for Post-COVID Fatigue Syndrome
This study aims to determine if low-dose naltrexone (LDN) reduces fatigue, improves related symptoms, and reduces inflammatory markers in peripheral blood in cases with Post-COVID-19 Fatigue Syndrome (PCFS) from COVID-19 (i.e.
- Trial name
- NCT05430152
- Testing
- Low-Dose Naltrexone
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- Luis Nacul
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