Clinical trials: Covid19, completed
COVID-19
Clinical Performance Evaluation of the Bio-Self™ COVID-19 Antigen Home Test
The purpose of this study is to evaluate the performance of the Bio-Self COVID-19 Antigen Home Test. The study will evaluate the accuracy (sensitivity and specificity) in a simulated home use environment when compared to a…
- Trial name
- NCT05334758
- Testing
- Bio-Self COVID-19 Antigen Home Test, Standard of Care COVID-19 Test, RT-PCR Test
- Where
- 3 sites in United States
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- BioTeke USA, LLC
COVID-19, Anxiety Syndrome
Prevalence and Risk Factors of Anxiety and Depression Among Policemen During the Health Crisis Linked to COVID-19
To date, there is little international data on depression and anxiety among police officers apart from studies carried out after an attack or natural disaster.
- Conditions
- COVID-19, Anxiety Syndrome, Depression Syndrome, Policemen
- Trial name
- Covid19-Police (NCT06076876)
- Where
- France
- Volunteers
- 600 people
- Sponsor
- University Hospital, Strasbourg, France
Parents During COVID-19
Expressive Writing for COVID-19 Resilience for Parents
The purpose of this study is to determine the impact of a 4-week, virtually-delivered expressive writing intervention on resilience in a cohort of parents and caregivers currently navigating the COVID-19 pandemic during spring \&…
- Trial name
- NCT04589117
- Testing
- Expressive writing
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Duke University
COVID-19
Convalescent Plasma for Treatment of COVID-19: An Exploratory Dose Identifying Study
Convalescent plasma has been shown to be safe and effective for treatment of several diseases. Preliminary data indicates that it is safe and effective for treatment of COVID.
- Trial name
- NCT04384497
- Testing
- SARS-CoV-2 convalescent plasma
- Where
- 2 sites in Sweden
- Volunteers
- 10 people
- Sponsor
- Joakim Dillner
COVID 19
Impact of Nasal Saline Irrigations on Viral Load in Patients With COVID-19
Nasal saline irrigations are a safe and commonly used mechanism to treat a variety of sinonasal diseases including sinusitis, rhinitis, and upper respiratory tract infections.
- Trial name
- NCT04347538
- Testing
- Saline Nasal Irrigation
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Vanderbilt University Medical Center
Covid19, ME/CFS
Innovative Support for Patients With SARS-COV2 Infections (COVID-19) Registry (INSPIRE)
The Innovative Support for Patients with SARS COV-2 Infections Registry (INSPIRE) study is a CDC-funded COVID-19 project to understand the long-term health outcomes in recently tested adults, both negative and positive, who have…
- Conditions
- Covid19, ME/CFS, SARS COV2, Novel Coronavirus Infection
- Trial name
- INSPIRE (NCT04610515)
- Where
- 8 sites in United States
- Volunteers
- 6,000 people
- Sponsor
- Rush University Medical Center
COVID-19
Safety of an Inactivated SARS-CoV-2 Vaccine for Prevention of COVID-19 in Children and Adolescents
This study is a multi-center and open design, phase Ⅳ clinical trial of an inactivated SARS-CoV-2 vaccine (CoronaVac) manufactured by Sinovac Research and Development Co., Ltd.The purpose of this study is to evaluate the safety…
- Trial name
- NCT04992208
- Testing
- Experimental Group
- Where
- China
- Volunteers
- 31,041 people, healthy volunteers welcome
- Sponsor
- Sinovac Life Sciences Co., Ltd.
SARS-CoV-2 (COVID-19) Severe Pneumonia
Study to Evaluate the Safety and Efficacy of ATYR1923 (Efzofitimod) In Participants With Severe Pneumonia Related to COVID-19
To evaluate the safety and preliminary efficacy of efzofitimod, compared to placebo matched to efzofitimod, in hospitalized participants with SARS-CoV-2 (COVID-19) severe pneumonia not requiring mechanical ventilation.
- Trial name
- NCT04412668
- Testing
- Efzofitimod 1 mg/kg, Efzofitimod 3 mg/kg
- Where
- 10 sites in United States, Puerto Rico
- Volunteers
- 36 people
- Sponsor
- aTyr Pharma, Inc.
Covid19, Emergencies
Prediction of the Patient Pathway in Emergency Room in an Exceptional Sanitary Situation
The COVID-19 outbreak leads to optimize the pathway in emergency departments. The length of time spent in the Emergency Department is linked to the morbi-mortality and the risk of COVID-19 transmission.
- Trial name
- 3PU-SSE (NCT04665778)
- Testing
- hospital bedroom booking
- Where
- France
- Volunteers
- 1,516 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Overheating
Thermoregulatory Reactions of Medical Workers Who Use Personal Protective Equipment From Biological Hazards
This research will provide data on thermal condition, functional status and working conditions of medical workers who use personal protective equipment from biological hazards.
- Trial name
- NCT05091515
- Testing
- Personal protective equipment from biological hazard
- Where
- Russia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Federal State Budgetary Scientific Institution "Izmerov Research Institute of Occupational Health"
Community Mental Health
Mental Health in Communities Affected by COVID-19 in Uganda
Introduction: During pandemics like the COVID-19, a significant number of the populace suffer from psychological distress (PD) that often abates naturally over time in the majority of people but persists in others to become…
- Trial name
- NCT04616989
- Testing
- Psycho-education, Comparator
- Where
- Uganda
- Volunteers
- 814 people, healthy volunteers welcome
- Sponsor
- Makerere University
Hyponatremia, Covid19
HYPONATREMIA IN COVID-19 PATIENTS
SYSTEMIC INFLAMMATION HAS BEEN ASSOCIATED WITH SEVERE COVID-19. HYPONATREMIA CAN RESULT FROM INFLAMMATION DUE TO NON-OSMOTIC STIMULI FOR VASOPRESSIN PRODUCTION.
- Conditions
- Hyponatremia, Covid19, Corona Virus Infection
- Trial name
- NCT04493268
- Where
- Argentina
- Volunteers
- 250 people
- Sponsor
- Hospital Nacional Profesor Alejandro Posadas
SARS-CoV-2 Infection, COVID-19
An Open-label, Clinical Feasibility Study of the Efficacy of Remdesivir for Long-COVID.
Following an infection with Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV2), one in ten people will experience persisting symptoms, or develop symptoms which can last for months and even years.
- Trial name
- ERASE-LC (NCT05911906)
- Testing
- Remdesivir
- Where
- 4 sites in United Kingdom
- Volunteers
- 73 people
- Sponsor
- University of Derby
Thrombosis, Covid-19
Thrombosis and Covid-19
The coronavirus disease of 2019 (COVID-19) is a viral illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), now deemed a pandemic by the World Health Organization.
- Conditions
- Thrombosis, Covid-19, SARS-CoV 2
- Trial name
- COVBIO (NCT04366778)
- Testing
- TEM-tPA
- Where
- France
- Volunteers
- 341 people
- Sponsor
- Hospices Civils de Lyon
COVID-19 Acute Respiratory Distress Syndrome
Positive End Espiratory Pressure Trial in Coronavirus Disease 19 Treated With Continuous Positive Airway Pressure
Consecutive patients with hypoxemic respiratory failure, CT evidence of bilateral pneumonia and diagnosis of Coronavirus Disease 19 (COVID-19) with molecular nasopharyngeal swab consecutively admitted to the COVID Care Unit of…
- Trial name
- NCT05178160
- Testing
- PEEP Standard Protocol
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Santa Maria delle Grazie Hospital
Vaccine Hesitancy, COVID-19
The Impact of a Web-based Psychoeducation Programme with a Motivational AI Chatbot on Covid-19 Vaccine Hesitancy
Vaccine hesitancy is defined as 'delay in acceptance or refusal of vaccines, despite the availability of vaccine service' and was named one of the top ten global health threats by the World Health Organization in 2019.
- Trial name
- NCT05531058
- Testing
- AI-driven Vaccine Communicator, Self-learning of COVID-19 vaccine knowledge
- Where
- Hong Kong
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
COVID-19
Compass Course: COVID-19
A group of clinicians and researchers developed an 8-session group intervention that integrates education, support, self-reflection, and action-expectation to help people reaffirm or reconstruct self-grounded purpose after…
- Trial name
- CC-COVID (NCT05295238)
- Testing
- Compass Course
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Allina Health System
Sars-CoV2, Severe Neurologic Injury
COVID-19 Brain Injury
A prospective cohort minimal risk study to determine the impact of the COVID-19 crisis on outcomes of neurologically injured ICU patients.
- Conditions
- Sars-CoV2, Severe Neurologic Injury, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- NCT04496076
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Pittsburgh
Physical Exercise, Disability Physical
Functional Training Improves the Functional Capacity and Physical Fitness of People Whit Spinal Cord Injury
The aim of this study is to understand the effect of adapted functional training on the physical fitness, functionality and quality of life of individuals with SCI after social distancing due to COVID-19.
- Trial name
- NCT06391658
- Testing
- Functional Training
- Where
- Brazil
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Centro Universitário Augusto Motta
Covid19
Process Evaluation of a Residence-Based SARS-CoV-2 Testing Participation Pilot
Mixed-methods process evaluation of a residence-based asymptomatic SARS-CoV-2 testing participation pilot
- Trial name
- RB-TPP (NCT05045989)
- Testing
- Residence-based testing participation pilot (SARS-CoV-2 testing with relaxed social distancing restrictions)
- Where
- United Kingdom
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
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