Clinical trials: Covid19
Respiratory Failure, Covid-19
Clinical Characteristics and Outcomes of Patients With COVID-19 on Mechanical Ventilation in Argentina
The main objective of the present study is to determine ICU and in-hospital mortality associated with COVID-19 infection and its independent predictors, in patients admitted to adult ICUs in Argentina with a requirement for…
- Conditions
- Respiratory Failure, Covid-19, Mechanical Ventilation
- Trial name
- SATICOVID19 (NCT04611269)
- Where
- 5 sites in Argentina
- Volunteers
- 950 people
- Sponsor
- Argentinian Intensive Care Society
Coronavirus Infection
Hydroxychloroquine in Outpatient Adults With COVID-19
Primary Objective: To assess the effect of hydroxychloroquine versus placebo on nasopharyngeal SARS-CoV-2 viral load in outpatient adults with COVID-19 Secondary Objectives: To assess the effect of hydroxychloroquine versus…
- Trial name
- NCT04333654
- Testing
- Hydroxychloroquine SAR321068
- Where
- 7 sites in United States, Belgium and 2 more
- Volunteers
- 8 people
- Sponsor
- Sanofi
Aerobic Exercise, Strength Training
Home-Based Circuit Training in Overweight/Obese Older Adult Patients With Knee Osteoarthritis and Type 2 Diabetes
Background: Obesity and type 2 diabetes mellitus (T2DM) are considered two of the most prevalent metabolic diseases linked to the onset of knee pain caused by osteoarthritis.
- Conditions
- Aerobic Exercise, Strength Training, Glycemic Control, Blood Pressure
- Trial name
- NCT06309654
- Testing
- 12-week home-based circuit training (HBCT), Standard of care (CONT)
- Where
- Saudi Arabia
- Volunteers
- 70 people
- Sponsor
- Princess Nourah Bint Abdulrahman University
Visual Impairment
Validity of at Home Visual Acuity Measurements for Telemedicine During Corona Virus (COVID-19) Pandemic
Prompted by the current COVID-19 pandemic, the American Academy of Ophthalmology has recommended the use of telemedicine to continue ophthalmic care while maintaining patient and provider social distancing.
- Trial name
- NCT04391166
- Testing
- Non invasive visual acuity testing
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Long-COVID, Post COVID-19 Condition
Sulfureous Water Therapy in Viral Respiratory Diseases
The goal of this double-blind, interventional, randomized case-control, pilot trial is to evaluate the effects of active sulfurous (STW) versus placebo (SDW) inhalations on blood test parameters, serum inflammatory cytokines…
- Conditions
- Long-COVID, Post COVID-19 Condition, Chronic COVID-19 Syndrome, Post Acute Sequelae of COVID-19
- Trial name
- STWandRVD (NCT06294756)
- Testing
- Inhalation of Sulfurous Thermal Water, Inhalation of Sterile Distilled non-pyrogenic Water
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Roma La Sapienza
Coronavirus Disease (COVID-19)
Plasma Rich Antibodies From Recovered Patients From COVID19
Prospective interventional study, single arm of purified convalescent plasma transfusion as an add on therapy for the standard of care treatment (national guideline) (Oseltamivir (75mg/12 hours for 5-10 days) and hydroxychroquine…
- Trial name
- PRA-001 (NCT04348877)
- Testing
- Antibody-Rich Plasma from COVID-19 recovered patients
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
COVID-19
Compassionate Use of Hyperbaric Oxygen Therapy
This is an observational patient registry of COVID-19 patients treated with HBOT.
- Trial name
- NCT04386265
- Where
- 11 sites in United States, Poland
- Volunteers
- 100 people
- Sponsor
- SerenaGroup, Inc.
COVID-19
Identification and Characterization of SARS-CoV-2 Specific CD8 T Cells in Humans
Background: The higher death rate from COVID-19 in the older population is associated with low CD8 T cell counts in the blood. Researchers want to learn the status of CD8 T cells specific to SARS-CoV-2 and their changes with…
- Trial name
- NCT04565067
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- National Institute on Aging (NIA)
Obesity
Exploring Optimal Treatment Components for Contactless Online Group-based Behavioral Weight Loss Program
The current pilot study will explore the optimal cost-effective treatment configuration for online group-based weight control by focusing on two aspects of our existing treatment program which have significant associated cost and…
- Trial name
- iREACH (NCT04514900)
- Testing
- Video Chat +Personalized Feedback, Video Chat + Basic Feedback, Discussion Board for Social Support +Basic Feedback
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Covid19, Cardiac Complication
One-year Cardiac Follow-up of Patients With COVID-19 Pneumonia
The primary objective of the study is to assess the cardiac status of COVID-19 pneumonia patients during 1 year after discharge
- Trial name
- NCT04501822
- Testing
- Evaluation of clinical, instrumental and laboratory diagnostics tests
- Where
- Russia
- Volunteers
- 380 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Influenza, COVID-19
Enhancing Protection Against Influenza and COVID-19 for Pregnant Women and Medically at Risk Children
Pregnant women and children with chronic medical conditions are at increased risk of hospitalisation, intensive care admission and death from influenza and COVID-19 infections.
- Trial name
- NCT05613751
- Testing
- Nudge
- Where
- 7 sites in Australia
- Volunteers
- 1,038 people
- Sponsor
- University of Adelaide
COVID-19
Antimicrobial Resistance During the SARS-CoV-2 (COVID-19) Pandemic
Assess the incidence and rates of resistant pathogens prior to and during the COVID-19 pandemic.
- Trial name
- NCT06334731
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Methodist Health System
Invasive Pulmonary Aspergillosis
Diagnosis of Invasive Pulmonary Aspergillosis, Specific Testing in Bronchial Secretions Versus Bronchoalveolar Fluid
The aim of this research project is to compare the results of Aspergillus specific test methods Aspergillus Galactomannan Enzyme Immunoassay (GM-EIA), Aspergillus polymerase chain reaction (PCR), Aspergillus Galactomannan Lateral…
- Trial name
- DipA2 (NCT04848831)
- Volunteers
- 100 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Covid19, Symptoms and Signs
COVID-19 And Lingering Symptoms In Primary Care Patients
The ongoing corona virus disease 2019 (COVID-19) is a viral acute respiratory tract infection caused by server acute respiratory syndrom coronavirus typ 2 (SARS-CoV-2).
- Trial name
- CALIP (NCT04813731)
- Where
- 13 sites in Belgium, Denmark and 9 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Katarina Hedin
Psychological Stress, Psychosocial Impairment
Evaluation of the Psychosocial Impact on Health Professionals Exposed During COVID 19 Coronavirus Pandemic
Application of a survey in electronic support to hospital professionals. This survey will include different demographics as well as questions from own elaboration about the different aspects related to the development of work…
- Conditions
- Psychological Stress, Psychosocial Impairment, Anxiety, Depression
- Trial name
- NCT04752839
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Perinatal Mental Health Care Practices During the COVID-19 Pandemic
Best Practices in Perinatal Mental Health During COVID-19
The COVID-19 pandemic has caused changes in health care during pregnancy, childbirth and postpartum. Although adverse effects of COVID-19 on perinatal mental health have been documented, changes in the perinatal mental health…
- Trial name
- NCT04779775
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Minho
COVID-19 Pneumonia
Safety and Effectiveness of Mesenchymal Stem Cells in the Treatment of Pneumonia of Coronavirus Disease 2019
The outbreak of coronavirus disease 2019 (COVID-19) at the end of 2019 has seen numerous patients experiencing severe acute lung injury (ALI), which developed into severe respiratory distress syndrome (ARDS).
- Trial name
- NCT04371601
- Testing
- Oseltamivir, hormones, oxygen therapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Fuzhou General Hospital
Coronavirus Infection, Sars-CoV2
Outcomes in Hospitalized Older Patients With COVID-19
In December 2019, the first patients infected with the 2019 novel coronavirus (2019-nCoV) were diagnosed in Wuhan. The clinical presentation and course of Severe Acute Respiratory Syndrome-CoV-2 (SARS-CoV-2) infection is poorly…
- Conditions
- Coronavirus Infection, Sars-CoV2, Elderly Infection, Old Age; Debility
- Trial name
- NCT04385212
- Where
- Switzerland
- Volunteers
- 230 people
- Sponsor
- University Hospital, Geneva
Hematologic Diseases
Clinical Study on the Impact of Covid-19 Vaccine on Allogeneic Hematopoietic Stem Cell Transplantation
Aim of this study will evaluate the Impact of Covid-19 vaccine on Safety and Efficacy of Hematological Patients Received Allogeneic Hematopoietic Stem Cell Transplantation.
- Trial name
- NCT05587881
- Testing
- COVID-19 vaccine(donor), COVID-19 vaccine(patient)
- Where
- China
- Sponsor
- The First Affiliated Hospital of Soochow University
Psychological, Mental Health Issue
STEP-COVID: A Program for Pregnant Women During the SARS-CoV-2 Pandemic
STEP-COVID (Supporting the Transition to and Engagement in Parenthood during the COVID-19 pandemic) is a manualized group intervention for pregnant women during the COVID-19 pandemic designed to foster emotion regulation and…
- Conditions
- Psychological, Mental Health Issue, Prenatal Stress, Maternal Distress
- Trial name
- NCT05419167
- Testing
- STEP-COVID
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Université du Québec à Trois-Rivières