Clinical trials: Covid19 Vaccination
Malignancies Multiple
Coronavirus Disease 2019 (COVID-19) Vaccination in Cancer Patients
The current study primarily aims to determine the status of vaccination in enrolled cancer patients and identify barriers to coronavirus disease 2019 (COVID-19) vaccination in cancer patients who have not been vaccinated.
- Trial name
- NCT04953065
- Testing
- COVID-19 vaccine hesitancy and acceptance survey
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Monika Joshi
COVID-19 Pandemic
MiVacunaLA: an Intervention to Improve COVID-19 Vaccination Behaviors Among Latinos
The aim of this study is to determine whether a community-informed, linguistically and culturally tailored educational program delivered via mobile phone is effective in improving vaccination behaviors among Latino families.
- Trial name
- NCT05234372
- Testing
- mivacunaLA
- Where
- 2 sites in United States
- Volunteers
- 468 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
COVID-19, Respiratory Disease
Health Communication to Influence COVID-19 Vaccination Intent and Message Propagation
This is a randomised controlled experiment in the form of a web based survey study which randomly exposes participants to different forms of public health messages, after which participants will be assessed on their intent to…
- Conditions
- COVID-19, Respiratory Disease, Vaccine Refusal, Infectious Disease
- Trial name
- CONVINCE (NCT05244356)
- Testing
- Health message exposure
- Where
- Malaysia
- Volunteers
- 5,784 people, healthy volunteers welcome
- Sponsor
- Clinical Research Centre, Malaysia
COVID-19
Project REMOTE (REimagining Measurements and Operations of Translational Endpoints)
This trial is designed to assess immunological biomarkers measured from blood samples that can be used to reliably predict how well vaccines work against symptomatic COVID-19 as well as to evaluate the feasibility of remote…
- Trial name
- REMOTE (NCT06776367)
- Testing
- Remote study participation and self-collection of specimens, Traditional clinical trial participation with clinician-collected specimens
- Where
- 16 sites in United States
- Volunteers
- 1,753 people, healthy volunteers welcome
- Sponsor
- Biomedical Advanced Research and Development Authority
HIV Seropositivity, Immunodeficiency
Evaluation of Post-SARS-CoV-2 Vaccinal Response in Immunocompromised Patients
The aim of this study is to identify both the humoral immunological response through the detection of induced antibodies and the cellular immunological response through the detection of interferon gamma production by functional…
- Conditions
- HIV Seropositivity, Immunodeficiency, Vaccination Reaction, Covid19
- Trial name
- NCT05672654
- Testing
- Blood draw
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
COVID-19
Study on Heterologous Prime-boost of Recombinant COVID-19 Vaccine (Ad5 Vector) and RBD-based Protein Subunit Vaccine
This is a randomized, observer-blind, placebo-controlled study, for evaluation of safety and immunogenicity of heterologous prime-boost immunization of recombinant COVID-19 vaccine (adenovirus type-5 vector) and RBD-based protein…
- Trial name
- NCT04833101
- Testing
- recombinant Ad5 vectored COVID-19 vaccine, RBD-based protein subunit vaccine (ZF2001) against COVID-19, trivalent split influenza vaccine
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention
Vaccination Refusal, COVID-19
COVID-19 Vaccine Uptake Trial
The goal of this study is to assess the best COVID-19 vaccine uptake strategy among students, staff and household members that have not been vaccinated.
- Trial name
- NCT05419232
- Testing
- Short Message Service (SMS) + Website Link Strategy, Phone Call with Peer Strategy
- Where
- 8 sites in United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Reside Either in Retirement Home or Long-term Care Units
Evaluation of Covid-19 Vaccination in Elderly Subjects in Retirement Home (EHPAD) and Long-term Care Units (USLD) in Ile-de-France
The main objective of this non-interventional, multi-center study is to compare the incidence of serious health events (death, unscheduled hospitalizations) in subjects vaccinated against Coronavirus with that of unvaccinated…
- Trial name
- COGEVAX (NCT04900376)
- Where
- France
- Volunteers
- 3,309 people, healthy volunteers welcome
- Sponsor
- Gérond'if
Autoimmune State, SARS-CoV-2 Infection
Security Efficacy COVID-19 Vaccination
Preliminary data support a possible molecular mimicry between SARS-CoV-2 and autologous components. This suggests the occurrence of autoimmunity during COVID-19. Consistently, autoimmunity may occur after SARS-CoV2 vaccination.
- Trial name
- SECVAX (NCT05743361)
- Testing
- Blood sampling
- Where
- Italy
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
SARS-CoV-2 Vaccination
Platelet and Immune Response in Covid-19 Vaccine
COVID-19 mRNA vaccines, administered with a two-dose regimen, have been shown to provide protection against Covid-19. However, the thromboinflammatory response toward these vaccines has never been explored as they exploit a…
- Trial name
- Vax-SPEED-IT (NCT05171959)
- Where
- Italy
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
COVID-19, Trust
Evaluating a Community-Led COVID-19 Testing Intervention to Address Mistrust - Study 1
The goal of this study is to assess how community-led group discussions about health-related topics may alter beliefs and intentions regarding healthcare recommendations, such as COVID-19 testing and vaccination.
- Trial name
- NCT06650462
- Testing
- Community-led discussion
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Old Dominion University
SARS-CoV 2
Current and Past SARS-CoV-2 Infection and COVID-19 in Healthcare With Regard to Vaccinations
To investigate the incidence of SARS-CoV-2 infections after vaccination, to monitor the development of SARS-CoV-2 antibody levels after vaccination and to compare this in relation to both previous health \& disease, previous…
- Trial name
- NCT04853004
- Testing
- SARS-CoV2 antibody measurement
- Where
- Sweden
- Volunteers
- 10,000 people
- Sponsor
- Karolinska Institutet
COVID-19
Safety and Immunogenicity Study of Booster Vaccination With COVID-19 Vaccine (Vero Cell),Inactivated From Different Manufactures for Prevention of COVID-19
This is a randomized, Open, control phase Ⅳ clinical trial of inactivated COVID-19 vaccine manufactured by Sinovac Research \& Development Co., Ltd,Beijing institute of Biological Products Co.,Ltd and Wuhan Institute of…
- Trial name
- NCT05165732
- Testing
- Experimental vaccine 1, Experimental vaccine 2, Experimental vaccine 3
- Where
- China
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Sinovac Research and Development Co., Ltd.
COVID-19, Vaccine Reaction
Immunogenicity and Reactogenicity Following a Booster Dose of COVID-19 mRNA Vaccine (Pfizer-BioNtech) and Two Adjuvanted Sub-unit Vaccines (SP/GSK) Administered in Adults Who Received 2 Doses of Pfizer-BioNTech mRNA Vaccine as a Primary Vaccination
The vaccination campaign in France began in early 2021 and was declared mandatory for all French people in July 2021. The efficacy of COVID-19 vaccines has since been widely demonstrated, as well as their safety, and now 60% of…
- Trial name
- COVIBOOST (NCT05124171)
- Testing
- BNT162b2, CoV2 preS dTM adjuvanted vaccine (D614), Sanofi/GSK, CoV2 preS dTM adjuvanted vaccine (B.1.351), Sanofi/GSK
- Where
- France
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
SARS-CoV-2
Efficacy and Safety of Oral Lactobacillus Plantarum GUANKE (CGMCC NO.21720) in Enhancement of Antibody Level After SARS-CoV-2 Vaccination (Trial 2)
Preliminarily explore the effect of oral probiotics in SARS-CoV-2 serum neutralizing antibody titer level and T cell response level (spot formation cell counting). Provide a reference for determining the appropriate oral regimen.
- Trial name
- NCT05195047
- Testing
- 1 week of probiotics(Week 1), 1 week of probiotics(Week 2)
- Where
- 2 sites in China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Peking University
CLL, Multiple Myeloma
The Capability of Haemato-oncology Patients to Generate Antibodies Against COVID-19
The corona pandemic is a continuing global challenge due to Corona Virus 2019 (COVID-19). The purpose of the study is to evaluate the capability of Haemato-oncology patients to generate antibodies against COVID-19 after infection…
- Conditions
- CLL, Multiple Myeloma, Lymphoma
- Trial name
- NCT04746092
- Where
- Israel
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
COVID-19
Heterologous Boost Immunization with an Aerosolised Ad5-nCoV After Two-dose Priming with an Inactivated SARS-CoV-2 Vaccine
This is a multicenter, open-label, partially radomized, parallel-controlled clinical trial to evaluate the safety and immunogenicity of heterologous prime-boost immunization with an aerosolised adenovirus type-5 vector-based…
- Trial name
- NCT05204589
- Testing
- Aerosolized Ad5-nCoV, Inactivated SARS-CoV-2 vaccine
- Where
- China
- Volunteers
- 10,285 people, healthy volunteers welcome
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention
Covid19
Comparison of the Immune Response to Natural COVID-19 Infection and Vaccination
The ongoing Coronavirus Disease 2019 (COVID-19) pandemic has been intensified by no population-based immunity to the severe acute respiratory disease coronavirus 2 (SARS-CoV2) and initially lack of effective treatments or…
- Trial name
- COVID19vac-1 (NCT04706390)
- Testing
- covid-19 vaccine
- Where
- Norway
- Volunteers
- 2,500 people
- Sponsor
- University of Bergen
Covid19
Anti-COVID19 AKS-452 Fusion Protein Vaccine - ACT Study
Combinatorial phase I/II safety, tolerability and immunogenicity single center open-label clinical study of AKS-452 COVID-19 vaccination study
- Trial name
- ACT (NCT04681092)
- Testing
- AKS-452
- Where
- Netherlands
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
COVID-19 Vaccines
Effectiveness of Vaccination Against COVID-19 in Brazil: Case-Control Study
The main objective of the study is to evaluate the effectiveness of the vaccine against covid-19, recommended by the national immunization program. This is a multicentric, observational, case-control study.
- Trial name
- NCT05621928
- Where
- Brazil
- Volunteers
- 3,920 people, healthy volunteers welcome
- Sponsor
- The Immunobiological Technology Institute (Bio-Manguinhos) / Oswaldo Cruz Foundation (Fiocruz)