Clinical trials: Covid19 Vaccination
Coronavirus Disease (COVID-19)
Long-Term Follow-up Survey of COVID-19 Vaccine After Vaccination
This study is a long-term follow-up survey of Japanese people after their second vaccination with the Moderna COVID-19 vaccine. The study sponsor will not be involved in how the participants are treated but will provide…
- Trial name
- NCT04941144
- Testing
- COVID-19 Vaccine
- Where
- Japan
- Volunteers
- 8,538 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
SARS-CoV-2 Infection, Thalasemmie, SCD
Monitoring of Anti-SARS-CoV-2 (COVID 19) and Encapsulated Vaccination Patients With Thalassemic and Falcemic Syndromes
There is an urgent need to rapidly evaluate anti-Covid 19 vaccination treatments, in terms of immune response (humoral and cell-mediated) together with the verification of the effectiveness of the vaccine in preventing SARS-CoV-2…
- Trial name
- HEMOGLOB-VAX (NCT05157256)
- Where
- 9 sites in Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Società Italiana Talassemie ed Emoglobinopatie
Long COVID-19
Antibodies and Immunity After Vaccination of Recovered Patients With COVID-19 and Long COVID-19 Symptoms
We investigated the association between immune system responsibilities in Long COVID patients and Full recovery patients.
- Trial name
- NCT05484700
- Where
- Thailand
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- Mahidol University
COVID-19
Effectiveness of a Second COVID-19 Vaccine Booster in Chinese Adults
This is a multicenter, parallel groups, partially randomized, open-label, blank-controlled adaptive platform study to evaluate the effectiveness of a second COVID-19 vaccine booster in Chinese adults who are charactered as the…
- Trial name
- NCT05855408
- Testing
- Intramuscularly administered Ad5-nCoV vaccine, Aerosolized Ad5-nCoV, DelNS1-2019-nCoV-RBD-OPT1
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention
COVID-19 Infection, Hematopoietic and Lymphatic System Neoplasm
Evaluation of Immunologic Response Following COVID-19 Vaccination in Children, Adolescents, and Young Adults With Cancer
This study evaluates immunologic response following COVID-19 vaccination in children, adolescents, and young adults with cancer. Vaccines work by stimulating the body's immune cells to respond against a specific disease.
- Conditions
- COVID-19 Infection, Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT05228275
- Testing
- Biospecimen Collection, Survey Administration
- Where
- 72 sites in United States
- Volunteers
- 549 people
- Sponsor
- Children's Oncology Group
Covid19
A Trial Among HealthCare Workers (HCW) Vaccinated With Janssen Vaccine: the SWITCH Trial
The key objective of the study is to measure the immune response against SARS-CoV-2 after different vaccinations in Health Care Workers (HCW) from 18 to 65 years old vaccinated once with Janssen vaccine.
- Trial name
- SWITCH (NCT04927936)
- Testing
- Vaccination once with Janssen vaccine (only priming), Vaccination with Janssen vaccine followed with Janssen vaccine (homologous boosting)., Vaccination with Janssen vaccine followed with Moderna vaccine (heterologous boosting).
- Where
- 4 sites in Netherlands
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Covid19, Vaccine Refusal
VEText Message Framing and Covid-19 Vaccine Uptake Among at Risk Veterans
This is a prospective, randomized controlled trial that will evaluate the effectiveness of two different targeted outreach interventions aimed at increasing Covid-19 vaccine uptake.
- Trial name
- VEText (NCT04805931)
- Testing
- Behavioral economics
- Where
- United States
- Volunteers
- 4,311 people, healthy volunteers welcome
- Sponsor
- VA Puget Sound Health Care System
Covid19, Vaccine Refusal
Impact of LA-CEAL HALT COVID-19 Ambassador Program on Likelihood to Vaccinate
The purpose of the study is to assess the effectiveness of the HALT COVID Ambassador educational outreach program on increasing likelihood to vaccinate against COVID-19
- Trial name
- NCT04930965
- Testing
- Community health worker engagement
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Tulane University
Quality of Life, Injection Site Reaction
Simultaneous mRNA COVID-19 and IIV4 Vaccination Study
This study is a prospective, randomized clinical trial. During this study, participants will be randomly assigned to receive quadrivalent inactivated influenza vaccine (IIV4) and mRNA COVID-19 vaccine either simultaneously or…
- Conditions
- Quality of Life, Injection Site Reaction, Adverse Drug Event, Systemic Reaction
- Trial name
- NCT05028361
- Testing
- mRNA COVID-19, IIV4
- Where
- 3 sites in United States
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Duke University
COVID-19 Infection
SaRS-Cov-2 Antibodies Following Exposure to Coronavirus Disease 2019 (COVID-19) and/or Vaccination in Nursing Homes
Presence of SaRS-Cov-2 antibodies following exposure to Coronavirus Disease 2019 (COVID-19) and/or vaccination is a major indicator of immunization. Few data exit about serology response in nursing homes (NHs), i.e.
- Trial name
- NCT04964024
- Testing
- SARS-CoV-2 antibodies
- Where
- France
- Volunteers
- 1,293 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
COVID-19 Vaccines, Telemedicine
Improving Pediatric COVID-19 Vaccine Uptake Using an mHealth Tool
This study will determine the effectiveness of a vaccine communication mobile health app on parental decisions to vaccinate their children against coronavirus disease 2019 (COVID-19).
- Conditions
- COVID-19 Vaccines, Telemedicine, Vaccine Hesitancy, Pediatric ALL
- Trial name
- MoVeUP (NCT05386355)
- Testing
- COVID-19 Vaccine Uptake App, General Health App
- Where
- 15 sites in United States
- Volunteers
- 1,934 people, healthy volunteers welcome
- Sponsor
- IDeA States Pediatric Clinical Trials Network
COVID-19, COVID-19 Immunisation
A Study to Evealuate Safety and Immunogenicity of TI-0010 SARS-CoV-2 Vaccine in Healthy Adults
This study is a randomized, double-blind, placebo controlled clinical exploratory study to evaluate the safety, tolerability and immunogenicity of TI-0010 vaccine in healthy adults aged 18-59.
- Trial name
- NCT06205524
- Testing
- TI-0010
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Drug Clinical Trial Institute of the Second Affiliated Hospital of Bengbu Medical College
COVID-19, SARS-CoV-2
Safety, Reactogenicity, and Immunogenicity Trial of CV2CoV mRNA Vaccine Against SARS-CoV-2 in Seropositive Adult Participants
Prevention of COVID-19 caused by SARS-CoV-2.
- Trial name
- NCT05260437
- Testing
- CV2CoV (2 µg), CV2CoV (4 µg), CV2CoV (8 µg)
- Where
- 24 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Covid19, Vaccine Adverse Reaction
Study of Sputnik V COVID-19 Vaccination in Adults in Kazakhstan
This study will assess the safety, reactogenicity, and immunogenicity of Gam-COVID-Vac (Sputnik V) vaccine intended to provide acquired immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing…
- Trial name
- NCT04871841
- Testing
- Sputnik V
- Where
- Kazakhstan
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Karaganda Medical University
COVID-19 Vaccines
COVID-19 Booster Dose Reminder/Recall for Adolescents
A single COVID-19 booster dose has been recommended in the United States for adolescents aged ≥12 years to enhance protection against SARS-CoV-2 infection.
- Trial name
- AIMED COVID (NCT05571657)
- Testing
- Reminder/Recall Sent Via Preferred Method of Communication
- Where
- United States
- Volunteers
- 4,304 people
- Sponsor
- Marshfield Clinic Research Foundation
Covid19
Methylation Effects of COV-19 Infection and Vaccinations
This is a retrospective non-randomized clinical study of 60 patients total to assess the effects of SARS-CoV-2 infection and the SARS-CoV-2 vaccination.
- Trial name
- NCT04939155
- Testing
- SARS-CoV-2 mRNA vaccine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- TruDiagnostic
Multiple Sclerosis
Assessment of Immune Response in Multiple Sclerosis Patients With COVID-19/Vaccination Treated With Ofatumumab and Other Disease Modifying Therapies
Vaccine responses in patients treated with anti-CD20 antibodies (ocrelizumab and ofatumumab) or S1P receptor modulators (fingolimod and siponimod) were evaluated before and after third SARS-CoV-2 vaccination as part of an ongoing…
- Trial name
- NCT05950308
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Covid19 Sequelae
Yale COVID-19 Recovery Study
The general purpose of the study is to determine the change in immune responses in people with Post-Acute Sequelae of SARS-CoV-2 Infection (PASC) after vaccination.
- Trial name
- NCT04895189
- Testing
- No intervention
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Yale University
Multiple Myeloma, AL Amyloidosis
COVID-19 VAX Booster Dosing in Patients With Hematologic Malignancies
To determine whether protective antibody levels increase after booster dosing with the Moderna COVID-19 vaccine in patients diagnosed with Hematologic Malignancies who have low antibody levels after a prior first vaccination with…
- Conditions
- Multiple Myeloma, AL Amyloidosis, Chronic Lymphocytic Leukemia
- Trial name
- NCT05028374
- Testing
- A single "booster" dose of the Moderna mRNA COVID-19 vaccine
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Multiple Sclerosis
Immune Response to COVID-19 Vaccine in Multiple Sclerosis Patients Treated With Teriflunomide and Alemtuzumab
Phase IV, 3-armed, prospective, open-label, single-center, Israeli study, examining the response to SARS-CoV-2 vaccination in 30 teriflunomide-, 10 alemtuzumab-treated patients, and 30 age-matched (for the teriflunomide group)…
- Trial name
- NCT05075499
- Testing
- COVID-19 vaccination
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Sheba Medical Center