Clinical trials: Covid19 Vaccine
Immunogenicity, Hematological Malignancies
Immunogenicity of Covid-19 Vaccination for Patients With Hematological Malignancies
Covid-19 is associated with a mortality rate of 33-37% in patients with hematological malignancies. At present, the anti-SARS-CoV-2 vaccination represents the most effective strategy for the prevention of Covid-19.
- Conditions
- Immunogenicity, Hematological Malignancies, Covid-19, Vaccine Response Impaired
- Trial name
- NCT04878822
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Ospedale di Circolo - Fondazione Macchi
mHealth, Social Media
Role of mHealth-based Interventions Including Social Media to Improve Childhood Immunization Coverage During COVID 19 Pandemic in Pakistan: Qualitative Study
In order to improve routine immunization uptake during COVID-19 pandemic, and to understand the perceptions and barriers related to vaccine hesitancy and coverage during COVID 19 and to explore the need for COVID-19 vaccination…
- Conditions
- mHealth, Social Media, Vaccine Hesitancy, Covid19
- Trial name
- NCT05042011
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
COVID-19 Vaccines
Improving COVID-19 Vaccine Uptake in Nursing Homes
SARS-CoV-2 vaccine, now being administered to skilled nursing facility (SNF) residents and staff, has highly variable acceptance between facilities.
- Trial name
- NCT04732819
- Testing
- High touch multi-pronged behavioral intervention
- Where
- 4 sites in United States
- Volunteers
- 23,768 people
- Sponsor
- Brown University
COVID-19, Vaccine Adverse Reaction
Adverse Events Report of Inactivated COVID-19 Vaccine
Numerous vaccination studies are conducted to protect against COVID-19 infection, and preclinical and clinical studies are still ongoing worldwide.
- Trial name
- NCT05026879
- Testing
- Inactivated COVID-19 vaccine (CoronaVac)
- Where
- Turkey (Türkiye)
- Volunteers
- 4,040 people, healthy volunteers welcome
- Sponsor
- Bozyaka Training and Research Hospital
COVID-19 Vaccines
Strategies for Combining the First Component of Sputnik V With Other Adenoviral or mRNA-based Vaccines.
To determine whether a heterologous vaccination regimen in individuals with no known previous history of COVID-19 is non-inferior to that observed with counterpart regimens currently in use in Argentina among persons aged 21 to…
- Trial name
- NCT05027672
- Testing
- Gam-COVID-Vac (rAd26) / Gam-COVID-Vac (rAd5)
- Where
- 2 sites in Argentina
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Ministerio de Salud de Ciudad Autónoma de Buenos Aires
COVID-19 Vaccines
Study to Evaluate the Immunogenicity and Safety of Heterologous SARS-CoV-2 Vaccine Schemes
To determine whether a heterologous vaccination regimen in individuals with no known previous history of COVID-19 is non-inferior to that observed with counterpart regimens currently in use in Argentina.
- Trial name
- NCT04962906
- Testing
- Gam-COVID-Vac / Gam-COVID-Vac
- Where
- Argentina
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Ministerio de Salud de Ciudad Autónoma de Buenos Aires
COVID-19 Vaccine, Older Adults
Safety and Immunogenicity of COVID-19 Vaccine Administered in Older Adults
The COVID-19 pandemic is causing unprecedented morbidity and mortality.The safe and effective Novel coronavirus vaccine is an effective means to block the transmission of the virus by building up the immune barrier of the…
- Trial name
- NCT05012800
- Testing
- COVID-19 Vaccine
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Beijing 302 Hospital
COVID-19 Respiratory Infection, Covid19
COVID-19 Vaccine Hesitancy and Dental Faculty Staff Members in Egypt
Healthcare workers (HCWs) play a vital role in determining the success of vaccination programs. Patient acceptance and vaccination rely greatly on the utilization and attitude of HCWs towards the vaccine, their attitude also…
- Conditions
- COVID-19 Respiratory Infection, Covid19, Vaccine Refusal
- Trial name
- NCT05009043
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mariam Ayman Amin Sharaf
Liver Diseases, Covid19
Safety and Immune Response of COVID-19 Vaccination in Patients With Chronic Liver Diseases
On 11 February 2020, the International Committee for the Classification of Viruses named the disease caused by SAＲS-CoV-2 infection in humans as the new coronavirus pneumonia (coronavirus disease 2019, COVID-19).
- Conditions
- Liver Diseases, Covid19, Adverse Reaction to Vaccine
- Trial name
- SIMPLE (NCT05007665)
- Testing
- SARS-COV-2 VACCINE
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Vaccine Refusal
Effect of COVID-19 Pandemic on Vaccination Compliance
1- Evaluate the impact of the COVID-19 pandemic on pediatric vaccinations compliance among children attending to Assiut University Children Hospital ,assess the general health profile of studied children.
- Trial name
- NCT04618796
- Testing
- vaccine
- Volunteers
- 100 people
- Sponsor
- Assiut University
Adult Who Received a First Dose of an mRNA Vaccine (Pfizer-BioNTech or Moderna) and Need to Receive a Second Dose
Compare Immunological Efficacy of a Vaccine Regimen Combining Two Covid19 mRNA Vaccines (Pfizer-BioNTech and Moderna) With That of a Homologous Vaccination of Each Covid19 mRNA Vaccine
As part of the COVID 19 vaccine campaign, the two mRNA vaccines, BNT162b2 (COMIRNATY®) and mRNA-1273 COVID-19 vaccine Moderna, are administered in two doses in subjects without a history of SARS-CoV-2 infection .
- Trial name
- ARNCOMBI (NCT04900467)
- Testing
- Pfizer, Moderna
- Where
- France
- Volunteers
- 418 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19 Vaccines
Study to Evaluate the Immunogenicity and Safety of Heterologous SARS-CoV-2 Vaccine Schemes in an Elderly Population
To determine whether a heterologous vaccination regimen in individuals with no known previous history of COVID-19 is non-inferior to that observed with counterpart regimens currently in use in Argentina among a population of…
- Trial name
- NCT04983537
- Testing
- Gam-COVID-Vac / Gam-COVID-Vac
- Where
- 2 sites in Argentina
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ministerio de Salud de Ciudad Autónoma de Buenos Aires
Cancer, Covid-19
Effectiveness of mRNA Covid-19 Vaccines on Cancer Patients:Observational Study. (ANTICOV)
Based on recent data, COVID (COV) vaccination in cancer patients (pts) is strictly recommended. For oncologic pts,2 types of m-RNA vaccines have been approved: BNT162b2 (Pfizer, Biontech) and mRNA-1273 (Moderna, NIAID).
- Conditions
- Cancer, Covid-19, Vaccine Response
- Trial name
- ANTICOV (NCT04878796)
- Testing
- Serum collection, adverse events collection
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Azienda Socio Sanitaria Territoriale di Cremona
Kidney Transplantation, SARS-CoV-2 Acute Respiratory Disease
Safety and Immunogenicity of 2-dose Inactivated COVID-19 Vaccine in Kidney Transplant Recipients
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has a major impact on transplant recipients, with mortality rates up to 20%.
- Conditions
- Kidney Transplantation, SARS-CoV-2 Acute Respiratory Disease, Vaccine
- Trial name
- NCT04969614
- Volunteers
- 300 people
- Sponsor
- West China Hospital
COVID-19 Vaccines
Comparative Evaluation of Covid-19 Vaccines Response
Study Population Population with vaccinated with three different Covid Vaccines (Inactive Vaccine (Sinovac Life Sciences, Beijing, China), recombinant human adenovirus serotype number 26 (rAd26 of Sputnik V), mRNA Vaccine…
- Trial name
- NCT04895007
- Testing
- Covid-19 Inactive Vaccine, recombinant human adenovirus serotype number 26, mRNA VAccine
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Covid19, Vaccine
Immunogenicity of the ChAdox1 n CoV-19 Vaccine With 12-dose Vial
ChAd0x1 nCoV-19 (AZD 1222) is the main vaccine that is planned to roll-out in Thailand and involve vaccinating people especially in high-risk categories.
- Conditions
- Covid19, Vaccine, Immunogenicity
- Trial name
- NCT04961385
- Testing
- Immunogenicity after first dose of participants who received first dose of ChAdox-1 n COV-19 vaccine
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
Covid19, Vaccine Refusal
VEText Message Framing and Covid-19 Vaccine Uptake Among at Risk Veterans
This is a prospective, randomized controlled trial that will evaluate the effectiveness of two different targeted outreach interventions aimed at increasing Covid-19 vaccine uptake.
- Trial name
- VEText (NCT04805931)
- Testing
- Behavioral economics
- Where
- United States
- Volunteers
- 4,311 people, healthy volunteers welcome
- Sponsor
- VA Puget Sound Health Care System
Is the Coronovac Vaccine Effective in Patients Receiving Chemotherapy
Investigation of the Effectiveness of CoronaVac Vaccine in Cancer Patients With Active Chemotherapy and Comparison With Healthy People.
This study aimed to investigate the effectiveness of CoronaVac vaccine, which is more than 90% protective in healthy people, in cancer patients receiving active chemotherapy.
- Trial name
- NCT04765215
- Testing
- CoronoVAC
- Where
- Turkey (Türkiye)
- Volunteers
- 291 people, healthy volunteers welcome
- Sponsor
- Asoc. Prof. Erdoğan Selçuk Şeber
Covid19 Vaccine
Investigating the Role of 13cis Retinoic Acid in the Treatment of COVID-19 and Enhancement of Its Spike Protein Based Vaccine Efficacy and Safety.
Investigating the role of 13cis retinoic acid in the treatment of COVID-19 and enhancement of Its spike protein based vaccine efficacy and safety.
- Trial name
- Isotretinoin (NCT04730895)
- Testing
- Oral 13 cis retinoic acid, Aerosolized 13 cis retinoic acid, 13 cis retinoic acid doses orally in combination with spike protein based vaccine
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
COVID-19 Vaccine, Corona Virus Infection
Quantification of Binding and Neutralizing Antibody Levels in COVID-19 Vaccinated Health Care Workers Over 1 Year
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic presents a great challenge to global health. The first case was identified in December 2019 in Wuhan, China and since has infected nearly 100 million…
- Conditions
- COVID-19 Vaccine, Corona Virus Infection, Vaccine Adverse Reaction, Vaccine Response
- Trial name
- NCT04910971
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- LifeBridge Health