Clinical trials: Cramps
Nursing Caries, Hemodialysis Complication
Muscle Cramps in Hemodialysis Patients: A Randomized Controlled Trial
Muscle cramps are a common and distressing issue among hemodialysis patients, significantly impacting their quality of life. Non-pharmacological approaches are increasingly being explored to alleviate these symptoms.
- Conditions
- Nursing Caries, Hemodialysis Complication, Exercise Addiction
- Trial name
- NCT06866470
- Testing
- relaxation group, massage
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people
- Sponsor
- University of Yalova
Amyotrophic Lateral Sclerosis, Muscle Cramp
TJ-68 Clinical Trial in Patients With Amyotrophic Lateral Sclerosis (ALS) and Muscle Cramps
The primary objective of the study is to demonstrate the safety and potential efficacy of TJ-68 for improving muscle cramps in participants with ALS based on a two-site, randomized, placebo-controlled double-blind multi-period…
- Trial name
- NCT04998305
- Testing
- TJ-68
- Where
- 3 sites in United States
- Volunteers
- 11 people
- Sponsor
- Hiroshi Mitsumoto
Hemorrhoids, Postoperative Pain
Botulinum Toxin A Before Hemorrhoidectomy to Prevent Postoperative Pain
Hemorrhoidectomy is an effective surgical treatment for advanced hemorrhoidal disease but is often associated with significant postoperative pain, which may delay recovery.
- Trial name
- BoTo-HEM (NCT07399860)
- Testing
- Botulinum toxin type A, Saline (0.9% NaCl)
- Where
- Russia
- Volunteers
- 292 people
- Sponsor
- Lomonosov Moscow State University Medical Research and Educational Center
Quadratus Lumborum Nerve Block, Postpartum Cramping
Quadratus Lumborum Block Reduced Postpartum Uterine Pain After Virginal Childbirth
With the continuous advancement of ultrasonic technology, nerve block in which drugs are injected into the periphery of the target nerve through ultrasonic guidance has become the mainstream method for postoperative pain control.
- Conditions
- Quadratus Lumborum Nerve Block, Postpartum Cramping, Vaginal Delivery
- Trial name
- NCT05371015
- Testing
- quadratus lumborum nerve block (ropivacaine ), quadratus lumborum nerve block (normal saline)
- Where
- Taiwan
- Volunteers
- 66 people
- Sponsor
- Chang Gung Memorial Hospital
Leg Cramp, Nocturnal
Effect of Theraworx/[pH]Uel on Night-time Leg Cramps and Spasm Symptoms
The purpose of this study is to determine the effect of Theraworx/[pH]uel on the frequency and severity of night-time cramps and spasms symptoms, including quality of life, depression and sleep quality when compared to a placebo.
- Trial name
- NCT03159260
- Testing
- Theraworx
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Sport and Spine Rehab Clinical Research Foundation
Muscle Cramp
Compression Stockings for Prevention of Hemodialysis Muscle Cramps
the Objectives of this clinical trial is : 1. examine the effect of using elastic compression stockings in the prevention of muscle cramps among hemodialysis patients. 2.
- Trial name
- NCT07293182
- Testing
- compression stockings
- Where
- 2 sites in Iraq
- Volunteers
- 82 people
- Sponsor
- Karbala University
Asthma, Bronchospasm
Single-Dose Cross-Over Study of the Effects of Albuterol-HFA in Exercise Induced Bronchoconstriction
This clinical study will evaluate and establish the protective effects of Amphastar's Albuterol Sulfate HFA Inhalation Aerosol (Albuterol-HFA), in preventing exercise-induced bronchoconstriction (EIB) in adolescent and adult…
- Trial name
- NCT00634829
- Testing
- albuterol (Armstrong Albuterol HFA), Albuterol Sulfate (Provenetil-HFA)
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Amphastar Pharmaceuticals, Inc.
Asthma, Bronchospasm
Escalating and Cumulative-Dose Study of Pharmacokinetics (PK), Pharmacodynamics (PD) and Safety of A006
The main objective is to evaluate the bronchodilatory efficacy, safety and pharmacokinetic profiles of A006 (Albuterol Dry Powder Inhaler (DPI)), in comparison with those of an active control, Proventil-HFA (Albuterol Metered…
- Conditions
- Asthma, Bronchospasm, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- NCT01189396
- Testing
- A006, Proventil-HFA
- Where
- 4 sites in United States
- Volunteers
- 27 people
- Sponsor
- Amphastar Pharmaceuticals, Inc.
Dystonic Disorders
Transcranial Magnetic Stimulation and Electrical Stimulation of Nerves to Study Focal Dystonia
This study will use transcranial magnetic stimulation (TMS) and electrical stimulation of nerves to examine how the brain controls muscle movement in focal hand dystonia (writer's cramp).
- Trial name
- NCT00050024
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Swelling, Trismus
Comparing Different Suturing Techniques on the Post-operative Morbidity After Removal of Impacted Mandibular Third Molar
This study compares the effect of two types of suturing techniques in the postoperative swelling and mouth opening after surgical removal of impacted mandibular third molar.
- Trial name
- NCT03492814
- Testing
- partial wound closure, total wound closure
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
Cranial Nerve Diseases, Facial Neuralgia
CSF Leak Following Microvascular Decompression: the Benefit of Routine Postoperative Lumbar Tap
Even at centers with very large experience, the risk of cerebrospinal fluid (CSF) leakage in surgery for microvascular decompression is reported up to 3%. Prevention of leakage is important since meningitis may follow.
- Conditions
- Cranial Nerve Diseases, Facial Neuralgia, Trigeminal Neuralgia, Hemifacial Spasm
- Trial name
- NCT01932255
- Testing
- prophylactic spinal tap, no prophylactic spinal tap
- Sponsor
- St. Olavs Hospital
Dystonic Disorder, Focal Dystonia
Characterization of Manual Dexterity by Finger Force Manipuladum (FFM) in Patients With Writer's Cramp and in Control Subjects
Writer's cramp is a focal dystonia characterized by abnormal movements and postures during writing. Limited finger independence during writing manifests as difficulty suppressing unwanted activations of neighbouring non…
- Conditions
- Dystonic Disorder, Focal Dystonia, Writer's Cramp
- Trial name
- FFM_CT (NCT03797638)
- Testing
- Finger Force Manipuladum (FFM)
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Chronic Anal Fissure
Botulinum Toxin Type A in the Treatment of Chronic Anal Fissure
This study is aimed at studying the effectiveness and safety of surgical treatment of chronic anal fissure.
- Trial name
- BTATCAF (NCT05598164)
- Testing
- Botulinum toxin type A
- Where
- Russia
- Volunteers
- 140 people
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Swelling/ Edema, Trismus
The Effect of Dexamethasone Submucosal Injection After Surgical Extraction of Lower Impacted Third Molars on Trismus and Edema
This clinical trial aims to investigate whether dexamethasone decreases edema and trismus in adults undergoing lower third molar surgical extraction.
- Trial name
- NCT06953440
- Testing
- Dexamethasone Sodium Phosphate Injection
- Where
- Saudi Arabia
- Volunteers
- 66 people
- Sponsor
- King Abdulaziz University
Swelling Lips &Amp; Face, Pain
Combination of Mixed Drugs vs Ibuprofen: a Randomized Clinical Trial
Combination of vitamins and melatonine compared with the conventional use of ibuprofen after surgical third molar extraction
- Conditions
- Swelling Lips &Amp; Face, Pain, Trismus
- Trial name
- CoctailRCT (NCT07133360)
- Testing
- Third molar extraction
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Arterial Spasm, Coronary Artery Disease
Transradial Evaluation Study of Diameter Increase After Vasodilatory Drugs Administration.
Radial artery access use in percutaneous cardiac interventions (PCI) is associated with a lower risk of vascular complications, bleeding and major adverse cardiac events including cardiac death in the long-term follow-up.
- Trial name
- TRIESTE (NCT04317846)
- Testing
- Intravenous administration of vasodilatory drugs
- Where
- 2 sites in Switzerland
- Volunteers
- 165 people
- Sponsor
- University of Lausanne Hospitals
Vein; Spasm, Patient Satisfaction
Effect of Topical Application of Black Pepper Essential Oil and Peripheral Catheter Insertion
The investigators aimed to determine the effects of topical application of black pepper essential oil on peripheral intravenous catheter insertion success.This randomized controlled trial was carried out on 60 patients randomly…
- Conditions
- Vein; Spasm, Patient Satisfaction, Nurse Scope, Practice
- Trial name
- NCT04796805
- Testing
- Topical essential oil application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- University of Yalova
Attention Deficit Disorder
Attention-Deficit Hyperactivity Disorder (ADHD) Study With Adults
This is a placebo controlled study evaluating the efficacy and safety of medication in adults with Attention-Deficit Hyperactivity Disorder (ADHD).
- Trial name
- NCT00048360
- Testing
- Extended-release bupropion hydrochloride
- Where
- 21 sites in United States
- Volunteers
- 162 people
- Sponsor
- GlaxoSmithKline
Hiv
Prospective Cohort Study of Adolescents Living With HIV and Their Caregivers Attending a Psychosocial Programme in Botswana
Adolescents/young adults with perinatally acquired HIV (PAH) face a number of antiretroviral (ART) adherence and well-being challenges.
- Trial name
- NCT03571555
- Testing
- Sentebale Psychosocial Programme
- Where
- Botswana
- Volunteers
- 516 people
- Sponsor
- Royal Holloway University
Coronary Artery Disease, Radial Artery Spasm
Association Between Radial Artery Access Point and Radial Artery Spasm
This prospective clinical study aims to investigate whether the puncture site distance from the radial styloid process affects the incidence of radial artery spasm (RAS) during coronary angiography.
- Trial name
- NCT07060820
- Testing
- Radial Artery Puncture at 0-20 mm, Radial Artery Puncture at >21 mm
- Where
- Turkey (Türkiye)
- Volunteers
- 380 people
- Sponsor
- Mersin Medicalpark Hastanesi