Clinical trials: Cramps
Impacted Mandibular Third Molar, Postoperative Pain
Effects of Platelet-Rich Fibrin After Mandibular Third Molar Surgery in Smokers and Nonsmokers
Mandibular third molar surgery is commonly associated with postoperative pain, swelling, and trismus. Platelet-rich fibrin (PRF) has been proposed as a biological adjunct to improve postoperative healing; however, its…
- Conditions
- Impacted Mandibular Third Molar, Postoperative Pain, Trismus, Facial Swelling
- Trial name
- NCT07604584
- Testing
- Platelet-Rich Fibrin
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara University
Hyperactivity, Chronic Rhinosinusitis (Diagnosis)
Prevalence of Nasal Hyperreactivity in Chronic Upper Airway Inflammation
Rhinitis, or inflammation of the nasal mucosa, can present with nasal obstruction, nasal discharge, itch or sneezing. If the sinusal mucosa is involved as well, it is called rhinosinusitis and facial pain or loss of smell is…
- Conditions
- Hyperactivity, Chronic Rhinosinusitis (Diagnosis), Chronic Rhinitis, Upper Respiratory Disease
- Trial name
- NCT03893227
- Testing
- Questionnaire
- Where
- Belgium
- Volunteers
- 756 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Sleep Wake Transition Disorders, Nocturnal Leg Cramps
Nocturnal Leg Cramps in Geneva : an Observational Study
Background : Nocturnal leg cramps (NLC) are defined as painful involuntary contractions of the lower limbs occurring during prolonged periods of rest, typically during the night.
- Trial name
- CNMI (NCT02548507)
- Testing
- observational study, no intervention
- Where
- Switzerland
- Volunteers
- 129 people
- Sponsor
- University of Geneva, Switzerland
Hemifacial Spasm
Observe Abnormal Potential From the Offending Vessel to the Facial Muscles of HFS Patients
The pathophysiologic basis of hemifacial spasm is cross-transmission between different branches of the facial nerve. The hypothesis is that the cross-transmission is mediated by the sympathetic nerve fibers on the surface of the…
- Trial name
- NCT01271634
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Attention Deficit Hyperactivity Disorder Symptoms
Caregiver Implementation Strategies Field Pre-Test
The purpose of this study is to field pre-test an implementation strategy resource package that aims to support caregivers in using behavioral interventions for children with hyperactive, inattentive, or impulsive behaviors.
- Trial name
- NCT06770036
- Testing
- Implementation Resource Package for Caregivers
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Hospital of Philadelphia
Pain, Physical Impairment
Enhancement of Physical Fitness in Older Adults
Ageing is related to a decrease in physical fitness, disability and age related symptoms like nocturnal leg cramps (NLC). Our research is focused on the enhancement of physical activity and mobility to increase physical fitness…
- Trial name
- NLC2010 (NCT01421628)
- Testing
- Fitness exercise program
- Where
- Netherlands
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Hanze University of Applied Sciences Groningen
Back Pain, Acute Pain
Tolperisone in Acute Muscle Spasm of the Back
This is a double-blind, randomized, placebo-controlled, parallel group study of the efficacy and safety of tolperisone (a non-opioid) or placebo administered as multiple doses three times a day (TID) in approximately 400 male and…
- Conditions
- Back Pain, Acute Pain, Back Spasm Upper Back, Back Strain
- Trial name
- STAR (NCT03802565)
- Testing
- Tolperisone
- Where
- 43 sites in United States
- Volunteers
- 415 people
- Sponsor
- Neurana Pharmaceuticals, Inc.
Oral Submucous Fibrosis
Effect of Laser Photobiomodulation in Improving Mouth Opening in Oral Submucous Fibrosis
This a patient and outcome assessor blinded, multiple arm, randomized placebo controlled clinical trial. The goal of the study is to study the adjunctive effect of 940nm laser photobiomodulation therapy (PBMT) in precancerous…
- Trial name
- OSMFPBMT (NCT06639009)
- Testing
- 940nm diode laser photobiomodulation, Conventional non -Invasive management in Oral Submucous fibrosis
- Where
- India
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Dr. Shalini Gupta
Angina Pectoris, Variant, Angina Pectoris; Spasm-Induced
ReACHallenge Trial: Acetylcholine Rechallenge After Pretreatment With Vasoactive Drugs
The goal of this clinical trial is to assess the feasibility and clinical value of acetylcholine (ACH) rechallenge after intracoronary verapamil +- nitroglycerine in a patient cohort with angina and non-obstructive coronary…
- Conditions
- Angina Pectoris, Variant, Angina Pectoris; Spasm-Induced, Angina Pectoris With Normal Coronary Arteriogram
- Trial name
- ReACHallenge (NCT05618132)
- Testing
- Acetylcholine rechallenge
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Antwerp
Muscle Cramps, Liver Cirrhosis
Baclofen in the Treatment of Muscle Cramps in Patients With Cirrhosis
Patients with cirrhosis often experience muscle cramps with varying severity. The mechanism of their occurrence is not yet understood.
- Trial name
- NCT02221570
- Testing
- Baclofen
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Acute Low-back Pain, Muscle Spasm; Back Pain
Efficacy and Safety of Etoricoxib/Tizanidine Versus Etoricoxib for Acute Low Back Pain Associated to Muscle Spasm
This is a Phase III, longitudinal, multicenter, randomized, double-blind clinical trial. The aim of the study is to evaluate the efficacy and safety of a fixed-dose combination of etoricoxib and tizanidine compared to etoricoxib…
- Trial name
- NCT06863662
- Testing
- Etoricoxib + Tizanidine fixed dose, Etoricoxib fixed dose
- Where
- Mexico
- Volunteers
- 136 people
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Attention Deficit Disorder With Hyperactivity
Study Evaluating the Safety and Efficacy of CLONICEL® to Treat Children and Adolescents With Attention Deficit Hyperactivity Disorder (ADHD)
The purpose of this study is to determine whether CLONICEL® (clonidine HCl sustained release) is a safe and effective treatment for children and adolescents with attention deficit hyperactivity disorder (ADHD).
- Trial name
- NCT00556959
- Testing
- high dose clonidine HCl sustained release, low dose clonidine HCl sustained release
- Where
- 13 sites in United States
- Volunteers
- 236 people
- Sponsor
- Addrenex Pharmaceuticals, Inc.
Radial Artery Injury
Nitroglycerin as Spasmolytic Regimen for RAS Prevention in Radial Center
The investigators will investigate whether administration of Nitroglycerin (NTG) as spasmolytic regimen reduces the incidence of moderate to severe radial artery spasm (RAS) in patients undergoing transradial catheterization in…
- Trial name
- NORAS (NCT03889470)
- Testing
- NTG 1 MG/ML Injectable Solution
- Where
- Indonesia
- Volunteers
- 1,000 people
- Sponsor
- Hermina Heart Center Kemayoran
Trigger Points, Myofascial, Cervical Postural Deviation
the Study Aim to Evaluate the Combined Therapeutic Effects of Dry Needling and Phonophoresis on Myofascial Trigger Points in Patient Suffering From Cervical Spine Postural Deviations. it Focuses on How These Interventions Help Reduce Pain, Relieve Muscle Spasm and Improve Functional Outcomes
Postural deviations of the cervical spine, particularly forward head posture (FHP) and altered cervical lordosis, are increasingly common in individuals with prolonged use of computers, mobile phones, and poor sitting posture.
- Trial name
- DNPP MTrP (NCT07601880)
- Testing
- Dry Needling + Phonophoresis, Dry Needling
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Asthma
Inhaled Albuterol Sulfate For Acute Wheezing Due To Obstructive Airways Disease In Children
This study evaluates the effect of cumulative dose administration of albuterol sulfate inhalation aerosol delivered with valved holding chamber and facemask.
- Trial name
- NCT00144846
- Testing
- albuterol sulfate inhalation aerosol
- Where
- 29 sites in United States, Puerto Rico
- Volunteers
- 80 people
- Sponsor
- GlaxoSmithKline
Attention Deficit Hyperactivity Disorder (ADHD), Anxiety Disorders and Symptoms
Safety and Efficacy of Mexidol® for ADHD in Children Aged 6-12
The primary objective of this study was to evaluate the efficacy and safety of Mexidol® film-coated tablets (125 mg) compared to a placebo in children aged 6 to 12 years with Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- MEGA (NCT06854601)
- Testing
- Mexidol
- Where
- 14 sites in Russia
- Volunteers
- 333 people
- Sponsor
- Pharmasoft
Hemodialysis, Renal Failure , Chronic
Comparative Study Between Leg Massage and Vibration on Cramps and Comfort for Patients Undergoing Hemodialysis
This planned randomized controlled trial will enroll 164 patients undergoing hemodialysis to compare the effectiveness of leg massage versus vibration therapy on muscle cramps and patient comfort.
- Trial name
- NCT07777354
- Testing
- massage, vibration
- Volunteers
- 160 people
- Sponsor
- University of Baghdad
Dystonia
Pilot Trial of Botulinum Toxin and Occupational Therapy for Writer's Cramp
Objective: Writer s cramp (WC) is a form of focal hand dystonia (FHD). Focal injections of botulinum toxin (BoNT) are the current best therapy. Past studies showed that some types of rehabilitative therapy can be useful.
- Trial name
- NCT02015039
- Testing
- BoNT Injections, Occupational Therapy
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Uterine Cramps, Postoperative Pain Management
Magnesium and Cramping
Hysteroscopy (an exam to look inside the uterus) is one of the most frequently performed procedures for patients with cervical or uterine disorders.
- Conditions
- Uterine Cramps, Postoperative Pain Management, Hysteroscopy
- Trial name
- NCT06745388
- Testing
- Magnesium sulfate, Ketamine
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Corewell Health East
Stroke Gait Rehabilitation
The Effectiveness of Laser and Extracorporeal Shock Wave Therapy in Resolving Ankle Muscle Spasm in Stroke Patients.
Stroke is one of the leading causes of long-term disability worldwide. Spasticity (muscle spasm) is a common and disabling consequence of stroke.
- Trial name
- spasticity (NCT07364110)
- Testing
- Rehabilitation Protocol, Extracorporeal Shock Wave Therapy (ESWT), High-Intensity Laser Therapy (HILT)
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Necmettin Erbakan University