Clinical trials: Cramps
Dysmenorrhea Primary, Dysmenorrhea
Effect of 'Cramp Bites' on Period Cramps in Women Aged 18-25
85 percent of women of reproductive age experience consistent period cramps/menstrual pain, and 60% indicate that they do not use painkillers to relieve menstrual symptoms; there is a need for natural and non-medicative…
- Conditions
- Dysmenorrhea Primary, Dysmenorrhea, Menstrual Discomfort, Menstrual Problem
- Trial name
- NUTRITION; GYN (NCT06227676)
- Testing
- Cramp Bites by Aunt Flo's Kitchen
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cornell University
Chronic Anal Fissure
Comparison of Lateral Internal Sphincterotomy Techniques for Chronic Anal Fissure
This prospective randomized controlled trial compares three lateral internal sphincterotomy (LIS) techniques in patients with chronic anal fissure refractory to medical treatment: (1) Spasm-Controlled LIS (serial small…
- Trial name
- SPHINX (NCT07520552)
- Testing
- Spasm-Controlled Lateral Internal Sphincterotomy, Lateral Internal Sphincterotomy up to Fissure Apex, Lateral Internal Sphincterotomy up to Dentate Line
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Çanakkale Onsekiz Mart University
Bronchospasm
INHALATION CHAMBER MANAGEMENT IN PEDIATRICS: EFFICACY OF AN EDUCATIONAL INTERVENTION IN PATIENTS DIAGNOSED WITH BRONCHOSPASM AND THEIR FAMILY CAREGIVERS.
Several studies show that unnecessary and frequent visits to the emergency department for bronchospasm care are associated with inadequate management of inhalers and poor education on the approach to respiratory distress.
- Trial name
- NCT05555134
- Testing
- educational intervention
- Where
- Spain
- Volunteers
- 134 people
- Sponsor
- Puerta de Hierro University Hospital
Attention Deficit Hyperactivity Disorder, ADHD
Time Course of Response to Methylphenidate HCl ER Capsules in Children 6 to 12 Years With ADHD in Classroom Setting
The time course of response following one dose of a new methylphenidate hydrochloride extended release capsule is studied in children 6-12 years in a simulated laboratory classroom setting.
- Trial name
- NCT01269463
- Testing
- Methylphenidate Hydrochloride Extended Release Capsule
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Rhodes Pharmaceuticals, L.P.
Asthma, Bronchospasm
Virtual Teach-to-Goal Education vs. Brief Education for Children
The purpose of this study is to evaluate the effectiveness of two different ways to teach hospitalized children how to use a metered dose inhaler and to follow-up after discharge home from the hospital to determine durability of…
- Conditions
- Asthma, Bronchospasm, Shortness of Breath
- Trial name
- V-TTG vs BI (NCT04373499)
- Testing
- Virtual Teach to Goal, Brief Intervention
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Neck Pain, Whiplash
PROCO Neck: The Course and Neuroplasticity in Neck Pain-Associated Disorders and Whiplash-Associated Disorders
Neck pain-associated disorders (NAD) and whiplash-associated disorders (WAD) are major health problems. NAD has a lifetime prevalence of 54%.
- Conditions
- Neck Pain, Whiplash, Pain, Acute, Psychosocial Functioning
- Trial name
- NCT05468684
- Testing
- no intervention
- Where
- Switzerland
- Volunteers
- 168 people
- Sponsor
- University of applied sciences
Impacted Third Molar Tooth
COMPARISON OF PIEZOSURGERY AND CONVENTIONAL ROTARY INSTRUMENTS IN IMPACTED THIRD MOLAR SURGERY
The purpose is to compare the effects of piezosurgery and conventional rotary instruments on postoperative pain, swelling, trismus and patients' comfort after mandibular third molar surgery.
- Trial name
- NCT03857035
- Testing
- Piezosurgery group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Type III Achalasia, EGJ Outflow Obstruction With Spastic/Hypercontractile Features
PREcision MEDicine In Achalasia (PREMEDIA) - Cohort
The goal of this observational study is to learn about how the doctor decides how long to cut t the esophageal muscle during Per-Oral Endoscopic Myotomy (POEM) in patients with difficulty swallowing due to certain conditions.
- Conditions
- Type III Achalasia, EGJ Outflow Obstruction With Spastic/Hypercontractile Features, Jackhammer Esophagus, Distal Esophageal Spasm
- Trial name
- PREMEDIA (NCT07293689)
- Where
- 16 sites in United States
- Volunteers
- 200 people
- Sponsor
- Northwestern University
Edema, Pain
The Impact of Arnica Montana Following the Surgical Extraction of Impacted Third Molars
Aim: The aim of this study is to evaluate the action of the homeopathic plant Arnica Montana on postoperative edema, pain and trismus after surgical extraction of impacted wisdom teeth.
- Conditions
- Edema, Pain, Trismus
- Trial name
- NCT06193720
- Testing
- Arnica montana
- Where
- Lebanon
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Liver Cirrhosis, Muscle Cramps
Study of Orphenadrine' in the Treatment of Muscle Cramps in Patients With Cirrhosis
Muscle cramps are common in patients with liver disease and associated with significantly diminished quality of life. Patients with cirrhosis often experience muscle cramps with varied frequency and severity.
- Trial name
- NCT02423395
- Testing
- orphenadrine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sherief Abd-Elsalam
Esophageal Motility Disorders
Endolumenal Partial Myotomy for Esophageal Motility Disorders
Achalasia and esophageal spasm are primary esophageal motility disorders where the lower esophageal sphincter fails to relax in response to swallowing with no well understood underlying cause.
- Trial name
- NCT01302301
- Testing
- Per oral endolumenal myotomy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The Oregon Clinic
Neuromuscular Blockade Reversal Agent, Perioperative Complications
Sugammadex-Induced Clenching During Neuromuscular Blockade Reversal
Study Objective: This study aims to evaluate the incidence, severity, and risk factors of sugammadex-induced mouth clenching during neuromuscular blockade (NMB) reversal in adult surgical patients.
- Conditions
- Neuromuscular Blockade Reversal Agent, Perioperative Complications, Anesthesia, General, Sugammadex
- Trial name
- NCT06962007
- Testing
- Sugammadex 1 mg/kg Group, Sugammadex 2 mg/kg Group, Sugammadex 4 mg/kg Group
- Where
- South Korea
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Nocturnal Leg Cramps, Myofascial Pain Syndrome
Exercise and Dry Needling Treatment Combination in Nocturnal Calf Cramps
The Investigators aim to evaluate the effectiveness of dry needling treatment in addition to stretching exercises on cramp duration, cramp intensity, cramp frequency, sleep quality, and sensitivity of myofascial trigger points in…
- Trial name
- NCT04789811
- Testing
- Stretching exercise, Dry needling
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kars State Hospital
Maximum Interincisal Opening
Effects of Exercise Therapy Adjuvant Device on Head and Neck Cancer Patients in the Treatment of Cancer Therapy Induced Trismus
Trismus is traditionally considered being a late effect of cancer therapy with functional deficits becoming clear in the first year after completing radiation therapy.
- Trial name
- NCT04740216
- Testing
- exercise therapy plus jaw device, exercise therapy
- Volunteers
- 130 people
- Sponsor
- Taipei Medical University
Bronchospasm; Bronchiolitis, Bronchospasm; Bronchitis
Efficacy and Safety Evaluation in Recurrent Wheezing Attacks
The study will be conducted in two hospitals of the same geographic area. It will be included children <3-years-old with recurrent wheezing attacks, confirmed by the review of the medical records, in the previous 12 months or a…
- Trial name
- MV130 (NCT01734811)
- Testing
- Biological vaccine
- Where
- 2 sites in Spain
- Volunteers
- 120 people
- Sponsor
- Inmunotek S.L.
Muscle Cramp
Oral Carnitine for Cramps in Pregnancy
Muscle cramps occur frequently among pregnant women, and few therapeutic options exist. This is a study of oral L-carnitine, a dietary supplement, for the treatment of muscle cramps in pregnancy.
- Trial name
- NCT00516516
- Testing
- L-Carnitine
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Southern California
Peripheral Arterial Disease
Supervised Treadmill Exercise and Ranolazine for Intermittent Claudication of Lower Extremities
The goal of this study is to evaluate whether supervised treadmill exercise combined with ranolazine 1000 mg twice daily provides an incremental benefit in absolute walking distance over supervised exercise alone in patients with…
- Trial name
- STERILE (NCT00914316)
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Corewell Health East
Vasospastic Angina
Multidetector Coronary CT In Vasospastic Angina
The purpose of this study is to compare the extent of coronary vessel stenosis between coronary spasm-induced angina attacks (named vasospastic angina, VSA) patients and health volunteers by multi-detector computed tomography…
- Trial name
- NCT02180971
- Testing
- Positive CAG with EG test, Negative CAG with EG test
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Dong-A University
Epileptic Encephalopathy, Early Infantile Epileptic Encephalopathy
IBIS - Investigating Reliability of BIS and SEDLINE Monitoring in Children With Developmental and Epileptic Encephalopathies (DEE).
When children have surgery, anaesthetists carefully monitor the depth of anaesthesia by using sensors on the forehead that measure brain activity, also known as processed electroencephalogram (pEEG).
- Conditions
- Epileptic Encephalopathy, Early Infantile Epileptic Encephalopathy, Infantile Spasm, Developmental and Epileptic Encephalopathies
- Trial name
- IBIS (NCT07585643)
- Testing
- Monitoring of patients using electroencephalogram, a Bispectral Index (BIS) and Sedline monitors.
- Where
- 2 sites in Australia, Brazil
- Volunteers
- 40 people
- Sponsor
- Telethon Kids Institute
Subarachnoid Hemorrhage
Stellate Ganglion Block as Adjuvant Therapy to ca Channel Blocker
Aim of work: To evaluate the effect of stellate ganglion block in prevention of cerebrovascular spasm in traumatic subarachnoid hemorrhage Primary outcome: Asses changes of cerebral blood flow velocity by Trans cranial Doppler.
- Trial name
- NCT04100824
- Testing
- stellate ganglion block by transcranial doppler, Nimodipine
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University