Clinical trials: Cramps
Cramp, Limb, Pregnancy Related
The Effect of Grounding During Pregnancy
The study was planned as a randomized controlled trial. The research data included a pregnant informed form, leg cramps evaluation form, Pittsburgh Sleep Quality Index, Visual Analog Scale for fatigue, Pregnancy-Related Anxiety…
- Trial name
- NCT05557188
- Testing
- Grounding
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Ege University
Lumbar Spinal Stenosis With Nocturnal Calf Cramps
Effect of Baclofen Treatment on Nocturnal Muscle Cramps in Patients With Lumbar Spinal Stenosis: a Randomized Clinical Trial
Nocturnal calf cramps is a common complaint in patients with lumbar spinal stenosis. The purpose of this study is to evaluate the effect of baclofen in lumbar spinal stenosis patients receiving conservative therapy.
- Trial name
- NCT05392361
- Testing
- gabapentin (neurontin® capsule 300mg) treatment, baclofen (baclofen Tab. 10mg) treatment
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Yonsei University
Muscle Cramp, Ache
7T Magnetic Resonance Spectroscopy and Skeletal Muscle Biopsy Findings in Statin Associated Adverse Muscle Events
Over 40 million Americans take statins to reduce their risk of atherosclerotic cardiovascular disease (ASCVD). Unfortunately, 10 to 20% stop taking them due to statin-associated muscle symptoms (e.g.
- Conditions
- Muscle Cramp, Ache, Weakness, Muscle, Statin Adverse Reaction
- Trial name
- NCT04507373
- Testing
- Simvastatin 40mg
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Texas Southwestern Medical Center
Muscle Cramps, Aromatherapy
The Effect of Aromatherapy Massage Applied to Hemodialysis Patients With Muscle Cramp
This study is a randomized controlled and single-blind study consisting of qualitative and quantitative stages to evaluate the effect of aromatherapy massage on cramp frequency, cramp pain severity and quality of life in crampy…
- Conditions
- Muscle Cramps, Aromatherapy, Hemodialysis, Quality of Life
- Trial name
- NCT04874857
- Testing
- Lavandula angustifolia, Rosmarinus officinalis L. and Origanum majorana L., Baby oil
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Muscle Cramp, Cirrhosis
Ropinirole for the Treatment of Muscle Cramps in Patients With Cirrhosis
The investigator's aim is to compare the efficacy of Ropinirole (Requip) to vitamin E in the treatment of muscle cramps in cirrhotic patients.
- Trial name
- NCT03176966
- Testing
- Vitamin E, Ropinirole, Muscle cramp survey
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Vanderbilt University Medical Center
Statin-related Muscle Pain, Muscle Aches
7 Tesla MRI Study in Patients With Statin Related Muscle Complaints
Roughly 5-10% of statin-treated patients report muscle pain, aches, weakness, cramps, stiffness, or "heaviness" - typically occurring symmetrically in the legs.
- Conditions
- Statin-related Muscle Pain, Muscle Aches, Muscle Weakness, Muscle Cramp
- Trial name
- NCT04575090
- Testing
- Simvastatin
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Dialysis; Complications
Effectiveness of Intradialytic Exercise on Reduction in Fatigue and Muscle Cramps
An experimental study to assess the Effectiveness of Intradialytic exercise on reduction in Fatigue and Muscle Cramps and Improvement in Muscle Strength among CKD patients undergoing Maintenance Haemodialysis at dialysis unit of…
- Trial name
- NCT05382468
- Testing
- Intradialytic exercise
- Where
- India
- Volunteers
- 62 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Calf Cramps During Pregnancy
Effect of Kinesio Tape Application and Stretching Exercises on Calf Cramps During Pregnancy
The aim of this study is to investigate the effect of kinesio-tape application and stretching exercise on calf muscle cramp during pregnancy
- Trial name
- NCT05281289
- Testing
- kinesio-tape, stretching exercise, instructions about dealing with calf cramps
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Back Pain, Acute Pain
Tolperisone in Acute Muscle Spasm of the Back
This is a double-blind, randomized, placebo-controlled, parallel group study of the efficacy and safety of tolperisone (a non-opioid) or placebo administered as multiple doses three times a day (TID) in approximately 400 male and…
- Conditions
- Back Pain, Acute Pain, Back Spasm Upper Back, Back Strain
- Trial name
- STAR (NCT03802565)
- Testing
- Tolperisone
- Where
- 43 sites in United States
- Volunteers
- 415 people
- Sponsor
- Neurana Pharmaceuticals, Inc.
Cirrhosis, Muscle Cramp
Non-Pharmaceutical Intervention for Cirrhotic Cramps Reduction: The NICCles Trial
This clinical trial is evaluating the feasibility of using a non-pharmaceutical treatment to improve the symptoms and severity of muscle cramps in patients with cirrhosis.
- Conditions
- Cirrhosis, Muscle Cramp, Ascites
- Trial name
- NCT04650295
- Testing
- Household Remedy, Tap water
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Michigan
Muscular Cramps, Hemodialysis
The Effect of the Massage on Cramp Frequency, Cramp Severity, and Sleep Quality
The aim of this randomized controlled experimental study was to determine the effect of the massage applied to hemodialysis patients with complaint of cramp on the cramp frequency, cramp severity, and sleep quality.
- Trial name
- Massage (NCT04990661)
- Testing
- intradialytic massage
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Kafkas University
Dystonic Disorder, Focal Dystonia
Characterization of Manual Dexterity by Finger Force Manipuladum (FFM) in Patients With Writer's Cramp and in Control Subjects
Writer's cramp is a focal dystonia characterized by abnormal movements and postures during writing. Limited finger independence during writing manifests as difficulty suppressing unwanted activations of neighbouring non…
- Conditions
- Dystonic Disorder, Focal Dystonia, Writer's Cramp
- Trial name
- FFM_CT (NCT03797638)
- Testing
- Finger Force Manipuladum (FFM)
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Nocturnal Leg Cramps, Myofascial Pain Syndrome
Exercise and Dry Needling Treatment Combination in Nocturnal Calf Cramps
The Investigators aim to evaluate the effectiveness of dry needling treatment in addition to stretching exercises on cramp duration, cramp intensity, cramp frequency, sleep quality, and sensitivity of myofascial trigger points in…
- Trial name
- NCT04789811
- Testing
- Stretching exercise, Dry needling
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kars State Hospital
Muscle Cramp
Intradialytic Stretching Exercises on Prevention and Reduction of Leg Muscle Cramps
Renal replacement therapy is a treatment option for people who have acute or chronic renal failure. A patient with increasing symptoms of renal failure is referred to a dialysis and transplantation center early in the course of…
- Trial name
- NCT04901832
- Testing
- Intradialytic stretching exercises
- Where
- Iraq
- Volunteers
- 60 people
- Sponsor
- Kufa University
Hiv
Prospective Cohort Study of Adolescents Living With HIV and Their Caregivers Attending a Psychosocial Programme in Botswana
Adolescents/young adults with perinatally acquired HIV (PAH) face a number of antiretroviral (ART) adherence and well-being challenges.
- Trial name
- NCT03571555
- Testing
- Sentebale Psychosocial Programme
- Where
- Botswana
- Volunteers
- 516 people
- Sponsor
- Royal Holloway University
Muscle Cramp, Stockings, Compression
Prevention of Leg Cramps Using Compression Stockings or Magnesium Supplements in the Age Group of 50 to 84
Leg cramps are painful sensations of tightening in the muscles of the legs, that are often associated with secondary insomnia. They are common especially at an older age.
- Conditions
- Muscle Cramp, Stockings, Compression, Magnesium
- Trial name
- CramP (NCT04694417)
- Testing
- Compression stocking, Magnesium tablet
- Volunteers
- 225 people
- Sponsor
- Tampere University Hospital
Hemodialysis Complication, Muscle Spasm
Hot and Cold Compress in Hemodialysis
Aims and objectives. To examine and compare the effects of hot and cold compresses administration on muscle cramps, fatigue, and comfort in hemodialysis (HD) patients. Background.
- Conditions
- Hemodialysis Complication, Muscle Spasm, Fatigue
- Trial name
- NCT04681521
- Testing
- Hot and Cold compress, nursing interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Nervous System Disease
PET Imaging of Phosphodiesterase-4 (PDE4) in Brain and Peripheral Organs of McCune-Albright Syndrome
Background: McCune-Albright Syndrome (MAS) is a disorder that affects the bones, skin, and some hormone-producing tissues. It is associated with a mutation in a gene. This gene affects enzymes in the brain and body.
- Trial name
- NCT02743377
- Testing
- Brain PET Imaging with 11C Rolipram, Whole Body PET Baseline with 11C Rolipram, Whole Body PET Blocked with Roflumilast
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- National Institute of Mental Health (NIMH)
Sleep-related Leg Cramps
Evaluate the Efficacy of Herbal Medicine (Shaoyao Gancao Decoction Jiawei) in Sleep-related Leg Cramps
Sleep-related leg cramps (SRLCs) are a sleep-related movement disorder whereby painful contractions of the calf or foot muscles arise at sleep onset and during sleep and awaken the patient, interrupting sleep.
- Trial name
- NCT04500730
- Testing
- Shaoyao Gancao Decoction Jiawei
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- Chinese University of Hong Kong
Perimenopause, Menstrual Cramps
Oral Micronized Progesterone Effects on Perimenopausal Menstrual Flow
This study is designed to evaluate the within-woman effect of oral micronized progesterone (Progesterone 300 mg at bedtime) on semi-quantitative menstrual flow measured by the DivaCup® (menstrual cup with volume indicators at…
- Trial name
- NCT02779582
- Testing
- Oral Micronized Progesterone
- Where
- Canada
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of British Columbia