Clinical trials: Cramps
Primary Dysmenorrhea, Menstural Cramps
Efficacy of CL25216 on Hormonal Balance and Menstrual Health in Women With Primary Dysmenorrhea.
This study is to evaluate the effects of CL25216 on hormonal balance and menstrual health in women with primary dysmenorrhea. Enrolled subjects will receive either CL25216 - 250 mg/day or placebo.
- Trial name
- PD (NCT07529561)
- Testing
- CL25216
- Where
- India
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- ApexCPG LLC
Primary Dysmenorrhea
Effects of Pau d' Arco in Primary Dysmenorrhea
A single arm, open-label trial evaluating safety and tolerability of encapsulated Tabebuia avellanedae in 12 generally healthy women aged 18-45 with primary dysmenorrhea (PDM).
- Trial name
- EPAPD (NCT04245540)
- Testing
- Pau d' Arco
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National University of Natural Medicine
Cardiac Catheterization, Spasm
Topical Radial Artery Vasodilation
The aim of the study is to facilitate radial artery access for cardiac catheterization. The investigators hypothesize that topical nitroglycerin and lidocaine will reduce radial artery spasm.
- Trial name
- NCT01155167
- Testing
- Nitroglycerin and lidocaine
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of California, San Francisco
Attention Deficit Disorder With Hyperactivity, Autistic Disorder
Methylphenidate in Children and Adolescents With Pervasive Developmental Disorders
This study will evaluate the efficacy and safety of methylphenidate for treating hyperactivity, impulsiveness, and distractibility in 60 children and adolescents with Pervasive Developmental Disorders (PDD).
- Conditions
- Attention Deficit Disorder With Hyperactivity, Autistic Disorder, Pervasive Development Disorders
- Trial name
- NCT00025779
- Testing
- methylphenidate, guanfacine
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Mental Health (NIMH)
Cramp, Limb, Pregnancy Related
The Effect of Grounding During Pregnancy
The study was planned as a randomized controlled trial. The research data included a pregnant informed form, leg cramps evaluation form, Pittsburgh Sleep Quality Index, Visual Analog Scale for fatigue, Pregnancy-Related Anxiety…
- Trial name
- NCT05557188
- Testing
- Grounding
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Ege University
Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder
Adverse Effect of Prolonged Methylphenidate Treatment on Cardiac Functions
The purpose of this study is to find out whether prolonged treatment with methylphenidate has any adverse effect on cardiac functions and measurements.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder, Attention Deficit Hyperactivity Disorder, Attention Deficit Disorders With Hyperactivity
- Trial name
- NCT00372359
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Ornit Cohen
Tendinopathy, Sprains and Strains
Study of LED Phototherapy for Musculoligamentous Lesions
The purpose of this study is to determine whether LED phototherapy using combined red and near infrared light (approved: Ministry of Health of Russian Federation No. 29/06070997/1080-00, EUROCAT Certificate No.
- Conditions
- Tendinopathy, Sprains and Strains, Muscle Spasm, Epicondylitis
- Trial name
- NCT00382941
- Testing
- Red and near infrared LED phototherapy device
- Where
- 3 sites in Ecuador
- Sponsor
- Hermano Miguel Foundation
Benign Essential Blepharospasm, Hemifacial Spasm
Effects of DaxibotulinumtoxinA for Blepharospasm and Hemifacial Spasm
The goal of this clinical trial is to test the effects of DaxibotulinumtoxinA-Lanm (Daxxify) in patients with benign essential blepharospasms (BEB) and hemifacial spasms (HFS). The main questions to answer: 1.
- Trial name
- NCT06195241
- Testing
- DaxibotulinumtoxinA
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Montefiore Medical Center
Impacted Third Molar Tooth
Evaluation of the Effects of Pre-operative Deflazacort on Post-operative Pain, Edema and Trismus
Removal of impacted lower third molar teeth is one of the most common oral surgical procedures, and these operations often lead to various complications in patients.
- Trial name
- NCT04365088
- Testing
- Deflazacort 30 MG Oral Tablet, Sugar pill
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Yuzuncu Yil University
Spasmodic Dysphonia, Singer's Dystonia
Brain Networks in Dystonia
To date, there is only limited knowledge about the distinct neural abnormalities that lead to the development of different forms of focal dystonia.
- Conditions
- Spasmodic Dysphonia, Singer's Dystonia, Writer's Cramp, Musician's Focal Hand Dystonia
- Trial name
- NCT03042962
- Testing
- MRI, Blood draw
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Hemifacial Spasm, Microvascular Decompression
Determination of Target of Adequate Partial Neuromuscular Blockade for Electrophysiologic Monitoring During Microvascular Decompression Surgery
There have been reports of monitoring LSR during MVD surgery helps predicting the clinical outcome of MVD.However, there have been no evidence of which degree of partial neuromuscular blockade should be performed or no…
- Conditions
- Hemifacial Spasm, Microvascular Decompression, Lateral Spread Response Monitoring
- Trial name
- NCT01598961
- Testing
- TOF count-guided partial NMB, T1/Tc guided partial NMB, No NMB
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Samsung Medical Center
Trismus, Radiation-induced Fibrosis
Physiotherapy for Radiation-induced Trismus
The purpose of this study is to assess the effect of two protocols of physiotherapeutic exercises in the maintenance and/or increase of the mandibular range of movement in patients suffering from head and neck cancer (HNC) who…
- Trial name
- NCT02094690
- Testing
- Therabite, Hyperboloid
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Endometriosis, Dysmenorrhea
Treatment of Endometriosis With Norethindrone Acetate ( NA) VS. Gonadotropin- Releasing Hormone (GnRH) Agonist (Lupron Depot 11.25 mg)
(A) Major 1) to compare the effectiveness of norethindrone acetate (NA) with GnRH agonist (Lupron-Depot-3) in relieving symptoms of endometriosis, 2) to compare bone density in the two treated groups in order to demonstrate that…
- Conditions
- Endometriosis, Dysmenorrhea, Dyspareunia
- Trial name
- NCT00458458
- Testing
- Norethindrone Acetate (NA), GnRH Agonist (Lupron Depot)
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Upper Back Pain
Exploratory Efficacy Study of Guaifenesin in Upper Back Pain
Explore the clinical efficacy of 7-day treatment regimens of guaifenesin in order to investigate the evidence that guaifenesin is an effective treatment for upper back/neck/shoulder muscle spasm/stiffness and pain.
- Trial name
- NCT01562548
- Testing
- Guaifenesin
- Where
- 5 sites in United States
- Volunteers
- 78 people
- Sponsor
- GlaxoSmithKline
Arthritis, Tendonitis
Prospective Analgesic Compound Efficacy (PACE) Study
A 24-week observational prospective study on the efficacy of topical non-steroidal anti-inflammatory drugs for the relief of pain.
- Conditions
- Arthritis, Tendonitis, Gout, Radiculopathy
- Trial name
- PACE (NCT02403687)
- Testing
- baclofen 2%, Bupivacaine hydrochloride 1%, Cyclobenzaprine hydrochloride 2%
- Volunteers
- 300 people
- Sponsor
- Express Specialty Pharmacy
Diarrhoea, Clostridium Difficile
Proof-of-Concept, Calcium Aluminosilicate Anti-Diarrheal (CASAD) for Treatment of Clostridium Difficile Infection
Clostridium difficile (C. difficile) can cause symptoms ranging from mild diarrhea to life-threatening colitis. Illness from C. difficile most commonly affects patients in hospitals and long-term care facilities and typically…
- Trial name
- NCT01570634
- Testing
- Calcium Aluminosilicate Anti-Diarrheal (CASAD)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Salient Pharmaceuticals Incorporated
Trismus
A Predictive Nomogram for Trismus After Radiotherapy for Head and Neck Cancer
Background: The aim of this study is to develop a prediction model for radiation-induced trismus (maximal interincisal distance equal to or less than 35 mm) based on a multivariable analysis of dosimetric and clinical factors.
- Trial name
- NCT05777668
- Testing
- Volumetric modulated radiotherapy
- Volunteers
- 104 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Hemodialysis Complication, Muscle Spasm
Hot and Cold Compress in Hemodialysis
Aims and objectives. To examine and compare the effects of hot and cold compresses administration on muscle cramps, fatigue, and comfort in hemodialysis (HD) patients. Background.
- Conditions
- Hemodialysis Complication, Muscle Spasm, Fatigue
- Trial name
- NCT04681521
- Testing
- Hot and Cold compress, nursing interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Impacted Third Molar Tooth
Evaluation of the Effects of Irrigation of the Extraction Socket With Rifamycine
Removal of impacted lower third molar teeth is one of the most common oral surgical procedures, and these operations often lead to various complications in patients.
- Trial name
- NCT04349579
- Testing
- Rifamycine, Saline Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Yuzuncu Yil University
Endothelial Dysfunction, Atherosclerosis
Blood Markers for Inflammation and Coronary Artery Vasoreactivity Testing in Patients With Chest Pain and Normal Coronary Arteries
The investigators are hoping to discover the cause of chest pain in patients with a normal coronary arteriogram. For patients with chest pain coronary angiography is the standard method by which the blood vessels of the heart can…
- Conditions
- Endothelial Dysfunction, Atherosclerosis, Inflammation, Myocardial Ischemia
- Trial name
- ACOVA (NCT01162824)
- Testing
- Acetylcholine, Adenosine
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- St George's Healthcare NHS Trust