Clinical trials: Cramps
Stroke, Cramp
The Application of Wide Pulse High Frequency Neuromuscular Electrical Stimulation in Disorders Associated With Motoneuron Hyperexcitability
In the present project, the investigators aim at proposing innovative ways of investigating spinal motoneuron hyperexcitability to counteract the associated impairments by using wide pulse high frequency neuromuscular electrical…
- Conditions
- Stroke, Cramp, Restless Legs Syndrome, Healthy Volunteers
- Trial name
- MnHyperex (NCT05908214)
- Testing
- wide pulse high frequency neuromuscular electrical stimulation training
- Where
- Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Kidney Diseases, End-Stage Kidney Disease
Outcomes of a Higher vs. Lower Hemodialysate Magnesium Concentration (Dial-Mag)
Many patients on hemodialysis have low levels of magnesium. Magnesium is needed to keep the heart, kidneys, and other organs working properly.
- Conditions
- Kidney Diseases, End-Stage Kidney Disease, Hemodialysis
- Trial name
- NCT04079582
- Testing
- Dialysate magnesium formulation of 1.5 mEq/L (0.75 mmol/L)., Dialysate magnesium formulation of ≤1.0 mEq/L (≤0.5 mmol/L).
- Where
- Canada
- Volunteers
- 25,000 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Coronary Artery Disease
Uric Acid Levels and Endothelial Functions
Uric acid is a risk factor for coronary artery disease (CED) in postmenopausal women but the association with inflammation and coronary microvascular endothelial dysfunction is not well-defined.
- Trial name
- NCT02862522
- Testing
- Questionnaire of overall health
- Where
- United States
- Volunteers
- 229 people
- Sponsor
- Mayo Clinic
Muscle Cramp, Renal Dialysis
Stretching Exercises for Dialysis Patients to Reduce Muscle Cramps
This single-center, parallel-group randomized controlled trial aims to evaluate the effect of a nurse-led intradialytic stretching program on the burden of muscle cramps in patients receiving maintenance hemodialysis (HD).
- Conditions
- Muscle Cramp, Renal Dialysis, Exercise Therapy, Nursing Care
- Trial name
- NCT07262879
- Testing
- Nurse-Led Intradialytic Stretching Exercises
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Attention Deficit Hyperactivity Disorder (ADHD), Autism Spectrum Disorder (ASD)
Exploring Eye Vergence Markers ADHD) and ASD
The investigators study aims to evaluate the utility of eye vergence, an eye-tracking measure, as an indicator of visuo-spatial attention in children aged 4-17 years and adults, using computer-based eye-tracking tasks.
- Trial name
- NCT06885060
- Testing
- BGaze ADHD Diagnostic Test, Oddball/Alerting Computer Task, Facical Emotion Computer Task
- Where
- 3 sites in Spain, United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Elizabeth Kilbey
Muscle Cramp, Stockings, Compression
Prevention of Leg Cramps Using Compression Stockings or Magnesium Supplements in the Age Group of 50 to 84
Leg cramps are painful sensations of tightening in the muscles of the legs, that are often associated with secondary insomnia. They are common especially at an older age.
- Conditions
- Muscle Cramp, Stockings, Compression, Magnesium
- Trial name
- CramP (NCT04694417)
- Testing
- Compression stocking, Magnesium tablet
- Volunteers
- 225 people
- Sponsor
- Tampere University Hospital
Myopia, Accommodation Spasm
Effect of VR and Accommdation Relax on Controlling Myopia in Children
This study evaluates the effect of virtual reality and accommodation relax technique on controlling onset and development of myopia in school-aged children.
- Conditions
- Myopia, Accommodation Spasm, Children
- Trial name
- NCT03427697
- Testing
- Virtual reality and accommodation relax techniques in combination
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Beijing Tongren Hospital
Bladder Cancer
COMPARISON OF OBTURATOR NERVE BLOCK TECHNIQUES IN TURBT
Bladder cancer is one of the most common cancers in older adults. The standard treatment for many bladder tumors is a surgical procedure called transurethral resection of bladder tumor (TUR-BT).
- Trial name
- NCT07481123
- Testing
- Subpectineal Obturator Nerve Block, Interfacial Obturator Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yavuz Saygılı
Wisdom Teeth, Edema Face
Comparison of the Effects of Intraoral Postoperative Dexamethasone Applications After Mandibular Third Molar Surgery
The aim of this study is to comparatively evaluate the effects of dexamethasone injected into the masseter muscle and pterygomandibular space after mandibular third molar surgery on postoperative pain, edema, trismus and quality…
- Conditions
- Wisdom Teeth, Edema Face, Trismus, Pain, Postoperative
- Trial name
- NCT06604286
- Testing
- In this group, patients received 8 mg IM dexamethasone injection into the masseter muscle after impacted tooth surgery., 8 mg IM dexamethasone injection into the pterygoid cavity after impacted tooth surgery.
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Afyonkarahisar Health Sciences University
Motor Neuron Disease, Benign Fasciculation-Cramp Syndrome
Serial Fasciculation Measurements in Motor Neurone Disease
Patients with motor neurone disease (MND) typically experience relentless motor decline and die within three years of symptom onset from respiratory muscle weakness.
- Trial name
- NCT03809845
- Testing
- High-density surface electromyography
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- King's College Hospital NHS Trust
Attention Deficit Disorder With Hyperactivity, HIV Infections
Assessment of Attentional Functioning in Children With HIV-1 Infection
Children with symptomatic HIV-1 (Human Immunodeficiency Virus) infection are at increased risk for developing severely disabling neurological and neuropsychological deficits.
- Conditions
- Attention Deficit Disorder With Hyperactivity, HIV Infections, Paralysis
- Trial name
- NCT00001497
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute (NCI)
Gastrointestinal Stromal Tumors (GISTs)
L-carnitine vs Placebo for the Treatment of Muscle Cramps After Imatinib in Gastrointestinal Stromal Tumors
we aim to evaluate the efficacy of L-carnitine for the treatment of muscle cramps after imatinib in patients with GIST and apply in the future.
- Trial name
- NCT03426722
- Testing
- L-carnitine
- Where
- South Korea
- Volunteers
- 4 people
- Sponsor
- Asan Medical Center
Leg Cramps in Pregnant Women
Kinesiotape Versus Compression Stockings on Pregnant Leg Cramps and Sleep Quality
Kinesiotape versus compression stockings on pregnant leg cramps and sleep quality
- Trial name
- NCT07683494
- Testing
- Control group, Kinesiotape group, Compression stockings group
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Oral Health, Molar, Third
Comparing Pain and Swelling After Surgical Extraction of Mandibular Third Molar in Dexamethasone Injection and Without Corticosteroid Methods
In some cases, impacted wisdom teeth should be extracted. Surgical extraction of these impacted third molars may provide special complication as pain, swelling, and trismus.
- Trial name
- NCT01896427
- Testing
- 21-benzyloxy-9alpha-fluoro-16alpha-methylpregna-1,4-dien-11beta,17alpha-diol-3,20-dione
- Where
- Iran
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Mohammad Javad Shirani
Hemifacial Spasm, Intraocular Pressure
Effect of Hemifacial Spasm on Intraocular Pressure Measurement
Twenty-four consecutive patients with Hemifacial spasm and 25 age and gender-matched randomly selected eyes of healthy volunteers underwent corneal pachymetry and intraocular pressure measurements using Goldmann Applanation…
- Trial name
- NCT03390803
- Testing
- effect of hemifacial spasm on intraocular pressure
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Medipol University
Type 1 Diabetes
The Summer Camp Study: Blood Glucose Control With a Bi-Hormonal Bionic Endocrine Pancreas
This study will test the hypothesis that a wearable automated bionic pancreas system that automatically delivers both insulin and glucagon can improved glycemic control vs.
- Trial name
- NCT01833988
- Testing
- Bi-hormonal Bionic Pancreas, Usual Care
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Massachusetts General Hospital
Postoperative Edema, Postoperative Pain
Hilotherapy vs. Kinesio Taping in Orthognathic Surgery Recovery
This prospective randomized controlled trial aims to compare the effects of kinesio taping and hilotherapy on postoperative edema, pain, and trismus in patients undergoing bimaxillary orthognathic surgery.
- Conditions
- Postoperative Edema, Postoperative Pain, Trismus, Orthognathic Surgery
- Trial name
- NCT07006610
- Testing
- Kinesio Tex® Gold Taping, Hilotherm® Facial Cooling System
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Medipol University
Writer's Cramp, Healthy Volunteers
Propensity to Develop Plasticity in the Parieto-Motor Networks in Dystonia From the Perspective of Abnormal High-Order Motor Processing
Background: People with dystonia have muscle contractions they can t control. These cause slow, repeated motions or abnormal postures. People with dystonia have abnormalities in certain parts of the brain.
- Conditions
- Writer's Cramp, Healthy Volunteers, Cervical Dystonia
- Trial name
- NCT02504905
- Testing
- TMS
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Primary Dysmenorrhea
Efficacy and Safety of DEH113 in the Treatment of Menstrual Cramp Pain Associated With Primary Dysmenorrhea
The purpose of this study if to evaluate the efficacy and safety of DEH113 in the Treatment of Menstrual Cramp Pain Associated With Primary Dysmenorrhea.
- Trial name
- LIBERTÀ (NCT06268054)
- Testing
- DEH113
- Volunteers
- 78 people
- Sponsor
- EMS
Impacted Mandibular Third Molar, Postoperative Pain
Effect of Platelet-Rich Fibrin on Postoperative Pain, Trismus, and Edema After Mandibular Third Molar Surgery
Impacted mandibular third molars are among the most commonly encountered conditions in oral and maxillofacial surgery. Surgical removal of these teeth is frequently associated with postoperative complications such as pain, facial…
- Conditions
- Impacted Mandibular Third Molar, Postoperative Pain, Trismus, Edema Face
- Trial name
- PRF-M3M (NCT07672951)
- Testing
- Platelet-rich fibrin (PRF), Sterile Absorbable Gelatin Sponge
- Where
- Pakistan
- Volunteers
- 134 people
- Sponsor
- PAEC General Hospital, Islamabad