Clinical trials: Cramps
Nervous System Disease
PET Imaging of Phosphodiesterase-4 (PDE4) in Brain and Peripheral Organs of McCune-Albright Syndrome
Background: McCune-Albright Syndrome (MAS) is a disorder that affects the bones, skin, and some hormone-producing tissues. It is associated with a mutation in a gene. This gene affects enzymes in the brain and body.
- Trial name
- NCT02743377
- Testing
- Brain PET Imaging with 11C Rolipram, Whole Body PET Baseline with 11C Rolipram, Whole Body PET Blocked with Roflumilast
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- National Institute of Mental Health (NIMH)
Cystic Fibrosis, Bronchospasm
Exercise-Induced Bronchospasm in Cystic Fibrosis
Exercise is an important clinical feature in cystic fibrosis. Better exercise capacity has been associated with better patient outcomes and quality of life.
- Trial name
- NCT00806455
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Ohio State University
Chronic Kidney Disease, Hemodialysis
Vibration Massage, Static Stretching Exercise, Intradialytic Muscle Cramps and Stress
Chronic kidney disease (CKD) is characterised by kidney damage that persists for 3 months or longer or an estimated glomerular filtration rate (eGFR) below 60 mL/min/1.73 m² and is assessed in 6 categories.
- Conditions
- Chronic Kidney Disease, Hemodialysis, Stress
- Trial name
- NCT06759376
- Testing
- Vibration massage, Static stretching exercise, Usual Care
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Figen Akay
Post Operative Pain
Evaluation of the Effect of Systemic Proteolytic Enzyme Therapy on Postoperative Inflammatory Response and QoL After Surgical Extraction of Impacted Mandibular Third Molars
1. To compare the postoperative pain between the patients who receive the systemic enzyme therapy and patients in the control group in the third and seventh day. 2.
- Trial name
- NCT05681312
- Testing
- systemic proteolytic enzyme (Tibrolin), Amoxicillin 500mg+metronidazole 500mg+ doliprane 100mg
- Where
- Iraq
- Volunteers
- 55 people
- Sponsor
- University of Baghdad
Asthma, Airway Hyperresponsiveness
Bronchospasm Associated With High Nitric Oxide
Intraoperative bronchospasm challenges anesthesia's safety. This study aims to investigate high concentration of exhaled nitric oxide as a marker of intraoperative bronchospasm.
- Trial name
- NCT00666510
- Where
- Brazil
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Attention Deficit Disorder With Hyperactivity
Effects of Animation Therapy on Children With ADHD
The aim of the study is to determine the effects of animation therapy on the main symptoms of Attention Deficit - Hyperactivity Disorder; hyperactivity, inattention and impulsivity.
- Trial name
- NCT05274282
- Testing
- Animation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Kutahya Health Sciences University
Pertussis, Whooping Cough
Safety and Dose Ranging Study of Acellular Pertussis and Acellular Pertussis -Tetanus-Diphtheria Booster Vaccines in Healthy Adults Ages 18 to 40 Years
This study will evaluate the safety and efficacy of 9 different vaccines containing aP (acellular pertussis) and TdaP (acellular pertussis, tetanus and diphtheria) in healthy subjects 18 to 40 years of age.
- Conditions
- Pertussis, Whooping Cough, Tetanus, Lockjaw
- Trial name
- NCT01529645
- Testing
- Acellular pertussis vaccine, Tetanus, reduced diphtheria, and acellular pertussis vaccine (adsorbed), Licensed TdaP booster vaccine
- Where
- Belgium
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Dystonic Disorder
Validation of the Zigzag Tracking Task Test for the Evaluation of Handwriting Difficulties in Writer's Cramp
Writer's cramp (WC) is a task specific dystonia that occurs from the moment patient starts writing. It leads to partial or complete inability to use the hand only during the handwriting gesture.
- Trial name
- LabyDys (NCT02882295)
- Testing
- Validation of a handwriting scale
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Asthma, Bronchospasm
Epinephrine Inhalation Aerosol USP, a HFA-MDI Study for Assessment of Pharmacokinetics
This study examines the pharmacokinetic profile of Armstrong's proposed Epinephrine Inhalation Aerosol USP, an HFA-MDI (E004), using a stable isotope deuterium-labeled epinephrine (epinephrine-d3) to differentiate the…
- Conditions
- Asthma, Bronchospasm, Wheezing, Shortness of Breath
- Trial name
- NCT01188577
- Testing
- Epinephrine Inhalation Aerosol, HFA, Epinephrine Inhalation Aerosol
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Amphastar Pharmaceuticals, Inc.
Muscle Cramps in Amyotrophic Lateral Sclerosis
Mexiletine for the Treatment of Muscle Cramps in ALS
The purpose of this study is to determine if mexiletine is effective for the treatment of muscle cramps in Amyotrophic Lateral Sclerosis (ALS).
- Trial name
- NCT01811355
- Testing
- Mexiletine
- Where
- 6 sites in United States
- Volunteers
- 23 people
- Sponsor
- Bjorn Oskarsson, MD
Liver Cirrhosis
Methocarbamol in Treatment of Muscle Cramps in Cirrhotic Patients
Muscle cramps markedly affect the quality of life in cirrhotic patients with no highly effective drug. Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms.
- Trial name
- NCT02642874
- Testing
- Methocarbamol, Calcium Carbonate
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Tanta University
KINESIOTAPING, Third Molar Extraction Surgery
Effect of Kinesio Taping of Pain, Swelling and Trismus After Mandibular Third Molar Surgery
This study evaluates the effectiveness of kinesio taping in reducing swelling, pain, and trismus complications after wisdom tooth extraction surgery.
- Conditions
- KINESIOTAPING, Third Molar Extraction Surgery, Pain, Swelling
- Trial name
- NCT06967246
- Testing
- Kinesio tape, non-elastic tape
- Where
- Vietnam
- Volunteers
- 17 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Peripheral Arterial Disease
Ultrasonic Perfusion Estimation in Calf Muscle
The purpose of this study is to evaluate the potential of ultrasound perfusion imaging technique for assessing the progression of peripheral arterial disease (PAD) and monitoring its response to therapy by measuring changes in…
- Trial name
- NCT04755335
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Mayo Clinic
Hemifacial Spasm
Hemifacial Spasm and Desflurane
Patients are chosen to participate in this study because they will undergo a particular type of brain surgery to treat their hemifacial spasm.
- Trial name
- HFS (NCT01726725)
- Testing
- desflurane
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Attention Deficit/Hyperactivity Disorder (ADHD)
Treatments for Fathers With ADHD and Their At-Risk Children (Fathers Too)
In contrast to mothers with Attention Deficit/Hyperactivity Disorder (ADHD), the impact of paternal ADHD in families and children with ADHD symptoms has not been studied, despite the prevalence of ADHD in males.
- Trial name
- NCT02675400
- Testing
- Vyvanse, Behavioral Parent Training, Methylphenidate
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Healthy, Premenstrual Dysphoric Disorder
The Effects of Mixhers HERTIME Supplements on Menstrual Symptoms
The purpose of this study is to assess Mixhers HERTIME supplements efficacy in alleviating menstrual cycle symptoms.
- Conditions
- Healthy, Premenstrual Dysphoric Disorder, Premenstrual Syndrome
- Trial name
- NCT06136104
- Testing
- Mixhers HERTIME
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Midwestern University
Dry Eye
Causal Relationship Between Dry Eye and Accommodative Spasm
To investigate the causal relationship of Sicca dry eye patients with presbyopic refractive error and accommodative spasm.
- Trial name
- NCT05120401
- Testing
- presbyopia glasses
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
NO DECOMPENSATED ILLNESS, Muscle Cramps
The Relationship of the Joint Blockage and Muscle Spasm
An interventional study aimed at verifying the effect of sacroiliac joint blockage on changes in piriformis muscle tension. The study was conducted on 40 subjects, both male and female.
- Conditions
- NO DECOMPENSATED ILLNESS, Muscle Cramps, Joint Dysfunction
- Trial name
- NCT07264530
- Testing
- Mobilization technique for sacroiliac joint
- Where
- Czechia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Asthma
Study to Assess Bronchospasm Potentially Induced by Next-Generation Propellant vs HFA Propellant in an MDI in Participants With Well/Partially Controlled Asthma
A study to assess bronchospasm potentially induced by HFO MDI as compared with HFA MDI in participants with well controlled or partially controlled asthma
- Trial name
- NCT05850494
- Testing
- HFA MDI, HFO MDI
- Where
- 4 sites in United States
- Volunteers
- 52 people
- Sponsor
- AstraZeneca
Attention Deficit Disorder With Hyperactivity
Cerebellar Loops and Attention Deficit Hyperactivity Disorder (ADHD)
The aim of this study is to investigate the integrity of connectivity between the neocortex and the cerebellum in the Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- TDA/H (NCT00684931)
- Testing
- Imaging
- Where
- 2 sites in France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux