Clinical trials: Creatine Supplementation
- Condition Creatine Supplementation
- Funder type Industry (pharma, biotech, devices)
- Accepts healthy volunteers yes
Safety of Short Term Creatine Hydrochloride Dosing
Short-Term Safety of Low-Dose Creatine Hydrochloride: A 28-Day Single-Arm Pilot Study
Background: Creatine monohydrate (typically 5-20 g/day) has a well-established safety profile across diverse populations. Creatine hydrochloride (CR-HCl) is a highly soluble creatine formulation that may allow effective…
- Trial name
- NCT07521059
- Testing
- creatine supplementation
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Vireo Systems, Inc.
Tyrosol, Creatine
The Effects of Tyrosol and Creatine on Exercise Performance and Cognition in Healthy Adults
This study will be a randomized, double-blind, placebo-controlled trial. It will be conducted over a 8-week intervention investigating the effects of creatine (5g Creatine monohydrate); placebo control (5g resistant dextrin), and…
- Conditions
- Tyrosol, Creatine, Endurance Performance, Cognition
- Trial name
- NCT07756658
- Testing
- Tyrosol, Creatine Monohydrate, Resistant Dextrin
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Tyrosol, Creatine
The Effects of Tyrosol and Creatine on Endurance, Strength, and Fatigue Resistance in Healthy Adults
The purpose of this clinical trial is to look at tyrosol's effects on endurance, strength, and fatigue resistance in humans. Additionally, the combination of tyrosol and creatine monohydrate will also be looked at to determine if…
- Conditions
- Tyrosol, Creatine, Endurance Performance, Cognition
- Trial name
- NCT06883292
- Testing
- Tyrosol, Creatine, Resistant Dextrin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Muscle Hypotrophy
Assessment of the Efficacy of Carnipure® AAS on Body Composition, Muscle Thickness, and Strength Adaptations in Healthy Men
This study is a 12-week randomized active control trial that is investigating the effects of Carnipure(R) AAS on muscle hypertrophy, body composition, and muscular strength adaptations in healthy men performing a resistance…
- Trial name
- NCT05681806
- Testing
- Carnipure AAS, Creatine Monohydrate
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Menopause, Estrogen Deficiency
ATENEA Study: Adherence to Creatine-Based Nutritional Supplementation in Estrogen-Depleted Women
This is a prospective, multicenter, observational clinical study conducted under routine clinical practice conditions aimed at describing adherence to a creatine-based nutritional supplement (Creaticare FEM) in estrogen-depleted…
- Trial name
- ATENEA (NCT07580846)
- Where
- 4 sites in Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Margan Biotech
Elevated S-adenosylhomocysteine
Role of a Dietary Supplement in Lowering SAH in Healthy Adults With Elevated Plasma SAH and Normal Homocysteine Levels
S-adenosylhomocysteine (SAH) is the end-product of methylation reactions in the body and the precursor to homocysteine. Elevated SAH in the blood is a reflection of the dysregulation of what is known as the S-adenosylmethionine…
- Trial name
- SAH (NCT05994794)
- Testing
- Alpha-GPC, Creatine and Ashwagandha (Sensoril®)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Standard Process Inc.
Creatine Absorption in Healthy Adults
Impact of OptiCreatine on Plasma Creatine and Gastrointestinal Effects in Males and Females
The study aims to evaluate the novel OptiCreatine formulation, which combines creatine with other bioactive compounds purported to enhance absorption and reduce gastrointestinal (GI) discomfort.
- Trial name
- NCT07225335
- Testing
- OptiCreatine, Creatine Monohydrate
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- TSI Group LTD
Nutritional Status
A Clinical Study to Investigate the Effects of Creatine Supplementation on Muscle Energetics and Cognitive Function in Young Healthy Male Athletes and an Ageing Population
This study will examine the impact of creatine supplementation on muscle function and cognitive performance in young and older subjects.
- Trial name
- NCT02058654
- Testing
- Creatine
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Physical Performance, Exercise Performance
The Acute Effects of Liquid IV's Pre-Workout Supplement on Muscle Endurance & Strength, Energy, and Cognition
The goal of this study is to learn if a new pre-workout supplement can improve exercise performance in healthy adults. It will also look at how the supplement affects mood and energy levels.
- Conditions
- Physical Performance, Exercise Performance, Endurance Exercise, Perceived Exertion
- Trial name
- NCT07225608
- Testing
- proprietary pre-workout supplement
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Sports Nutritional Sciences
New Method Using Deuterium Labelled Creatine to Measure Total Body Skeletal Muscle Mass
Creatine (methyl-d3) dilution (D3-creatine) is a novel technique for the estimation of muscle mass. The method uses a dose of deuterium-labelled creatine to determine total skeletal muscle mass via estimation of total body…
- Trial name
- NCT02519751
- Testing
- D3 Creatine, Creatine
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy
An Open-Label, Two-Arm Pilot Study of the Tolerability, Consumer Acceptability, and Exploratory Well-Being Outcomes of a Multi-Ingredient Protein Formula in Two Flavors in Healthy Adults
This is an open-label, two-arm pilot study designed to evaluate the tolerability, consumer acceptability, and well-being outcomes of a multi-ingredient protein formula, available in two flavors (Vanilla Protein Formula and…
- Trial name
- NCT07827014
- Testing
- Vanilla Protein Formula, Chocolate Protein Formula
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Qualia Life Sciences
Nutritional Status
Effect of Using Whey Protein and Creatine Supplements on Muscular Strength in Weight-training Adult Males
The purpose of this study was to evaluate the effect of combined whey protein and creatine supplement, as compared with whey protein supplement alone, on change in upper and lower body strength.
- Trial name
- NCT02094781
- Testing
- Whey protein and creatine supplement, Whey protein only supplement
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Side Effects of Creatine Monohydrate Dosing
Gastrointestinal and Fluid Retention Symptoms Associated With Creatine Monohydrate With and Without Loading Dose Over 28 Days of Supplementation
This study aimed to investigate the incidence and severity of GI symptoms associated with daily CM supplementation, with and without a loading phase, in healthy male and female adults.
- Trial name
- NCT07176325
- Testing
- Creatine Monohydrate
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vireo Systems, Inc.