Clinical trials: Creatine Supplementation
Exercise Performance Recovery
Effects of Creatine and Carbohydrate Supplementation on Endurance Performance
This study will examine the independent and combined effects of creatine and carbohydrate supplementation on exercise performance, compared to placebo.
- Trial name
- NCT07712653
- Testing
- Creatine Monohydrate, Carbohydrate, Creatine Monohydrate and Carbohydrate
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Amyotrophic Lateral Sclerosis
Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis
The objective of this study is to determine whether creatine slows disease progression in subjects with amyotrophic lateral sclerosis (ALS).
- Trial name
- NCT00005766
- Testing
- Creatinine
- Where
- United States
- Sponsor
- National Center for Research Resources (NCRR)
Health Behavior
Creatine Supplementation and Resistance Training in Premenopausal Females
The goal of this clinical trial is to determine the effects of creatine monohydrate and resistance training on lean mass, sleep, muscular strength, and perceived menstrual cycle symptoms in untrained premenopausal females.
- Trial name
- NCT05745870
- Testing
- Creatine Monohydrate Supplementation
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Idaho
Amyotrophic Lateral Sclerosis
Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis [ALS]
The purpose of this study is to evaluate the safety and effectiveness of creatine treatment in amyotrophic lateral sclerosis (ALS). There is currently no known effective treatment for ALS.
- Trial name
- NCT00005674
- Testing
- Creatine
- Where
- United States
- Sponsor
- National Center for Research Resources (NCRR)
Heart Failure
Clinical Evaluation of LEft VEntricular Auto Threshold Algorithm (LEVEA)
The purpose of the LEVEA study is to assess the performances of a new automatic left ventricular auto threshold (LVAT) algorithm (In-Clinic LVAT algorithm) when used by physicians during in-hospital follow-up.
- Trial name
- LEVEA (NCT03014180)
- Testing
- "In-Clinic LVAT"
- Where
- France
- Volunteers
- 60 people
- Sponsor
- LivaNova
Tyrosol, Creatine
The Effects of Tyrosol and Creatine on Exercise Performance and Cognition in Healthy Adults
This study will be a randomized, double-blind, placebo-controlled trial. It will be conducted over a 8-week intervention investigating the effects of creatine (5g Creatine monohydrate); placebo control (5g resistant dextrin), and…
- Conditions
- Tyrosol, Creatine, Endurance Performance, Cognition
- Trial name
- NCT07756658
- Testing
- Tyrosol, Creatine Monohydrate, Resistant Dextrin
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Psychosis
Transcranial Direct Current Stimulation and Cognitive Remediation Therapy for Psychosis
The proposed pilot study is a randomized controlled study to assess effectiveness of transcranial direct current stimulation (tDCS) to enhance cognitive remediation therapy in patients with psychotic disorders. tDCS.
- Trial name
- NCT02085421
- Testing
- tDCS
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Minnesota
Exercise, Physical Performance
Examination of Certain Blood Parameters Following Performance and Acute Exercise at Specific Times of the Day
This study aims to investigate whether the time of day at which acute exercise is performed influences physical performance and acute hormonal and biochemical responses in healthy young male soccer players.
- Conditions
- Exercise, Physical Performance, Circadian Rhythm
- Trial name
- Acute & Blood (NCT07825740)
- Testing
- Standardized Acute Exercise Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Firat University
Primary Lateral Sclerosis, Hereditary Spastic Paraplegia
Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis
This study will use a magnetic resonance imaging technique called nuclear magnetic spectroscopy (H-MRS) to define the pathology and progression of primary lateral sclerosis, hereditary spastic paraplegia and amyotrophic lateral…
- Conditions
- Primary Lateral Sclerosis, Hereditary Spastic Paraplegia, Amyotrophic Lateral Sclerosis
- Trial name
- NCT00023075
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Creatine
Creatine Supplementation in Female Collegiate Dancers
This study will be a 6 week creatine supplementation intervention with performance familiarization and pre and post testing. Participants will report to the human performance laboratory (HPL) for baseline to read and sign an…
- Trial name
- NCT05109039
- Testing
- Creatine
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Idaho
Post-partum, Women
Creatine for Recovery and Thinking in Mothers
The purpose of this randomized, double-blind, parallel-group trial is to compare the effects of two doses of creatine monohydrate (5 g/day versus 10 g/day) administered for four weeks in postpartum women.
- Trial name
- CREATE-MOM (NCT07795853)
- Testing
- Creatine Monohdyrate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
Dialysis; Complications
Intradialytic Creatine Supplementation
We perform a pilot study to investigate whether intra-dialytic creatine supplementation via the dialysate will result in higher intra-erythrocyte creatine concentrations.
- Trial name
- NCT05148208
- Testing
- Creatine supplementation to dialysate
- Volunteers
- 16 people
- Sponsor
- University Medical Center Groningen
Down Syndrome (DS), Supplementation
Effects of Chronic Creatine and Beta-Hydroxy-Beta-Methylbutyrate Supplementation on Oxidative Stress, Inflammation, Muscle Strength, and Body Composition in Individuals With Down Syndrome
Purpose: This study will test whether 8 weeks of creatine and HMB supplementation can improve muscle strength, body composition, balance, and overall health in people with Down syndrome.
- Trial name
- NCT07213063
- Testing
- Nutrition education, Supplement
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Universidad de Burgos
Type 1 Diabetes
Impact of Eccentric Training in Hypoxia With Creatine on Metabolic Control and VO2max in Patients With Type 1 Diabetes
Exercise plays an important role in treatment of diabetes. In recent years exercise training in normobaric hypoxia is used in training programs for athletes and in rehabilitation and also commercially.
- Trial name
- NCT06345612
- Testing
- hypoxia, normoxia, creatine supplementation
- Where
- Poland
- Volunteers
- 28 people
- Sponsor
- Silesian Centre for Heart Diseases
Sarcopenia
Creatine-Guanidinoacetic Acid Supplementation for Sarcopenia (CREGAAS)
Sarcopenia-driven brain and muscle creatine deficit could be seen as a distinctive pathological facet of this condition, and this might be approached with targeted therapies in aim to restore creatine homeostasis in target…
- Trial name
- CREGAAS (NCT04652921)
- Testing
- Creatine-guanidinoacetic acid, Inulin
- Where
- Serbia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Parkinson's Disease
NET-PD LS-1 Creatine in Parkinson's Disease
The purpose of this trial is to determine if the nutritional supplement creatine slows the progression of Parkinson's disease over time.
- Trial name
- NCT00449865
- Testing
- creatine
- Where
- 50 sites in United States, Canada
- Volunteers
- 1,741 people
- Sponsor
- University of Rochester
Breast Cancer
Creatine and Cognitive Health in Patients With Early-stage Breast Cancer During and After Chemotherapy Treatment
The goal of this clinical trial is to evaluate whether oral creatine supplementation can prevent chemotherapy-related cognitive impairment in patients with early-stage breast cancer undergoing neoadjuvant or adjuvant…
- Trial name
- IARA (NCT07372144)
- Testing
- Creatine
- Where
- Brazil
- Volunteers
- 227 people
- Sponsor
- D'Or Institute for Research and Education
Heart Failure
Care-HF CArdiac Resynchronization in Heart Failure
The CARE-HF trial evaluates the effects of Cardiac Resynchronization (CR) therapy on the mortality and morbidity of patients with heart failure due to left ventricular systolic dysfunction already receiving diuretics and optimal…
- Trial name
- NCT00170300
- Testing
- Implantable Cardiac Resynchronisation (pacing) device
- Volunteers
- 813 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Muscle Loss
The Effect of Creatine on Muscle Loss
The primary aim of this study is to determine the effect of creatine supplementation on muscle mass loss during short-term immobilisation in healthy, young people.
- Trial name
- CML (NCT01894737)
- Testing
- Creatine supplementation
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Knee Osteoarthritis
Effects of Creatine and Glucoseamine/ Chondritin Sulfate Co-Supplementation in Addition to Exercise and Physical Therapy in Patients With Knee Osteoarthritis
Osteoarthritis is the 11th highest contributor to disability world wide. In terms of conservative management of patients with knee osteoarthritis, Resistance exercise has been shown to be an effective intervention for reducing…
- Trial name
- NCT04423432
- Testing
- Lower Extremity Resistance Exercise Training, Home Exercise Plan, Electrotherapy + Heating
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Foundation University Islamabad