Clinical trials: Critical Care, Intensive Care
Critically Ill
Ultrasound of the Diaphragm in ICU Patients
Diaphragmatic dysfunction is an important complication of mechanical ventilation. Critically ill patients admitted in a teaching hospital intensive care unit will be evaluated with diaphragm ultrasound to investigate predictors…
- Trial name
- NCT01952262
- Testing
- diaphragm ultrasound
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Università Vita-Salute San Raffaele
Oral Cancer, Hypopharyngeal Cancer
Acupuncture Effect on Digestion in Critically Ill Post-Operative Oral and Hypo-pharyngeal Cancer Patients
Background: Head and neck cancer patients are in high risk to suffer from malnourishment, a risk that increase in postoperative condition and with the use of enteral nutrition (EN).
- Trial name
- NCT03934294
- Testing
- Specific acupuncture group, Metoclopramide 10mg, Non-specific acupuncture group
- Where
- Taiwan
- Volunteers
- 28 people
- Sponsor
- China Medical University Hospital
Post ICU Syndrome, Chronic Pain
Early Care Program for the Management of Post-ICU Syndrome and Chronic Pain After COVID-19 Infection.
COVID-19 (coronavirus 2019) disease has led to a large number of hospital admissions, many of which require admission to intensive care (ICU).
- Conditions
- Post ICU Syndrome, Chronic Pain, Covid-19
- Trial name
- PAIN-COVID (NCT04394169)
- Testing
- Intervention program
- Where
- Spain
- Volunteers
- 102 people
- Sponsor
- Hospital Clinic of Barcelona
Intensive Care Unit Acquired Weakness, Critical Care
TryCYCLE: A Pilot Study of Early In-bed Leg Cycle Ergometry in Mechanically Ventilated Patients
Background: Patients in the intensive care unit (ICU) are the sickest in hospital, and need advanced life-support. Survivors of critical illness are very vulnerable to weakness and disability.
- Conditions
- Intensive Care Unit Acquired Weakness, Critical Care, Mechanical Ventilation, Respiratory Failure
- Trial name
- TryCYCLE (NCT01885442)
- Testing
- In-bed leg cycle ergometry
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- McMaster University
Respiratory Distress Syndrome, Adult, Respiratory Insufficiency
Personalised Simulation Technologies for Optimising Treatment in the Intensive Care Unit
This project aims to develop software models describing how critically ill patients respond to changes in their treatment whilst admitted to an Intensive Care Unit (ICU).
- Trial name
- PSTOTICU (NCT04297397)
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Critical Illness
Blood Glucose Control Over an Extended Glucose Control Range in Postoperative Cardiac Surgery Patients in the Intensive Care Unit
Hyperglycaemia is commonly found in critically ill patients. Clinical studies demonstrated that tight blood glucose control in medical and surgical ICU patients results in a significant better outcome for the patients.
- Trial name
- Aldea_02 (NCT00882427)
- Testing
- enhanced model predictive control algorithm (eMPC)
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- B. Braun Melsungen AG
Critical Illness, Transportation Accidents
Intra-Hospital Transport of Critically Ill Patients in Intensive Care Unit
Intra-hospital transport is a frequent procedure in the ICU, involving patients with the highest severity scores. Although some studies estimate the rate of adverse events to be around 33% during intra-hospital transport…
- Conditions
- Critical Illness, Transportation Accidents, Intensive Care Unit
- Trial name
- TIGRHOU (NCT06455696)
- Where
- France
- Volunteers
- 645 people
- Sponsor
- French Society for Intensive Care
Quality of Life
Health-related Quality of Life and Nursing-sensitive Outcomes in Mechanically Ventilated Patients
This study will allow us to determine the perceived Health-Related Quality of Life (HRQL) a year after ICU discharge, and compare it with HRQL measured earlier on in the process, as well as analyse the negative experiences they…
- Trial name
- NCT02636660
- Volunteers
- 184 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Critical Illness, Enteral Nutrition
Trial of Enteral Glutamine on Intestinal Permeability in Critically Ill Patients
Glutamine-induced recovery in intestinal barrier function by reducing bacterial translocation was demonstrated in previous studies.
- Conditions
- Critical Illness, Enteral Nutrition, Intestinal Permeability
- Trial name
- NCT03113240
- Testing
- Glutamin, Maltodextrin
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Shahid Beheshti University
Pediatric Critical Illness
Transcutaneous pO₂ Monitoring in PICU
Arterial blood gas analysis is commonly used in pediatric intensive care units (PICUs) to assess oxygen and carbon dioxide levels in critically ill children.
- Trial name
- NCT07478380
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul Medeniyet University
Acute Respiratory Failure, Critical Illness
Exhaled Breath Condensate Analysis in Mechanically Ventilated Patients
Mechanically ventilated intensive care patients will be sampled for a small amount of exhaled breath condensate from the ventilator circuit and for venous blood.
- Trial name
- NCT06189924
- Testing
- Proteomic analysis of exhaled breath condensate
- Where
- 2 sites in Czechia
- Volunteers
- 200 people
- Sponsor
- The Institute of Molecular and Translational Medicine, Czech Republic
Pain Management, Music Therapy
MUSIDORE PED Study
The aim of this study is to measure the efficacy of music during a painful procedure in pediatric intensive care unit. Music therapy has real effects on the pain level already proven in adults units.
- Trial name
- MUSIDORE (NCT03916835)
- Testing
- Pain evaluation ( FLACC scale) before and during the cleaning care with and without music therapy.
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Covid19 and Mortality
Factors Affecting Mortality in Critical Patients Admitted to Intensive Care Unit Due to Coronavirus Disease 2019
Gazi Yasargil Training and Research Hospital, located in Diyarbakır province in southeastern Turkey, was designed as a pandemic hospital from the beginning of the coronavirus disease-2019 (COVID-19) outbreak.
- Trial name
- NCT04659876
- Testing
- clinical features and laboratory values
- Where
- Turkey (Türkiye)
- Volunteers
- 445 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
ECMO Treatment, ARDS
Hemodynamic Monitoring and Fluid Responsiveness in Venovenous Extracorporeal Membrane Oxygenation (VV ECMO) - "HemodynamECMOnitoring-VV Study"
In extracorporeal membrane oxygenation (ECMO), blood is drawn out of the body via tubes, oxygenated in an artificial lung; and then pumped back into the blood vessels.
- Conditions
- ECMO Treatment, ARDS, Pneumonia, Intensive Care
- Trial name
- NCT06593717
- Testing
- Transthoracic Echocardiography, Uncalibrated Pulse Contour Analysis, Transpulmonary Thermodilution/Calibrated Pulse Contour Analysis
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Intensive Care (ICU) Myopathy, Intensive Care Unit Acquired Weakness
Effect of Neurophysiological Facilitation Techniques in Intensive Care Patients
The aim of this study was to investigate the effect of neurophysiological facilitation techniques on respiratory and functional levels in intensive care patients.
- Trial name
- NCT05282576
- Testing
- NPF Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Saglik Bilimleri Universitesi
Intensive Care Unit Syndrome, Critical Illness
Effectiveness of Stress Management Training in Reducing Caregiver Burden and Perceived Stress in ICU Families
This research helps to close an important gap in the provision of care to ICU families and introduces a structured and accessible psychological intervention to family caregivers of long-stay ICU patients.
- Trial name
- NCT07812376
- Testing
- Stress Management Training Program
- Volunteers
- 50 people
- Sponsor
- Al-Balqa Applied University
Pain, Pain Management
Individualized Analgesia in the Intensive Care Unit With a New Pain Assessment Bundle and Protocolized Analgesia Adjustments
Both severe pain and opioid therapy are associated with negative effects. The experience of pain is common in the intensive care unit, but it is highly individual and difficult to assess, as patients are often unable to…
- Conditions
- Pain, Pain Management, Critical Illness
- Trial name
- INVISIBLE (NCT07473115)
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- University of Zurich
Critical Illness
Feasibility Study on Implementing Consultation-based High-quality Palliative Care Services in Intensive Care Units
Critically ill patients in intensive care units (ICUs) receive life-sustaining treatments aimed at restoring or maintaining organ function.
- Trial name
- NCT06490835
- Testing
- High-quality palliative care through consultation-based palliative care services in the ICU
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul National University Hospital
Critical Illness
Cost Effectiveness Analysis of Critical Care in Resource Limited Setting
The purpose of this study was to examine the cost effectiveness of critical care in a middle income country with limited resources. The main study hypothesis was that critical care is cost effective in low resources setting.
- Trial name
- CEACCLR (NCT02556476)
- Testing
- mechanical ventilation, neuromuscular blockade, renal replacement therapy
- Volunteers
- 148 people
- Sponsor
- University of Sarajevo
Muscle Weakness
Evaluation of Effectiveness of Combining High Protein Intake With Early Physical Exercise During Critical Illness
Assessment of Effectiveness of combined high protein intake with early physical exercise by ultrasound measurement of rectus femoris muscle thickness in Intensive Care Unite mechanically ventilated patients.
- Trial name
- NCT05877989
- Testing
- Amino Acid, Physical exercise
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University