Clinical trials: Critical Care
Cross Infection
Electronic Hand Hygiene Monitoring and ICU Infection Rates
If patients acquire a new infection whilst in hospital this can cause significant morbidity, prolonged hospitalisation and even death. Indeed, there is much public concern about infections such as MRSA.
- Trial name
- HANDS (NCT02511925)
- Testing
- Weekly poster of unit performance, Daily email of personal feedback, Active reminder from badge
- Where
- United Kingdom
- Volunteers
- 1,065 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Critical Illness, ICU Patients
Intensive Care Unit Rehabilitation Protocols
The aim of this study was to investigate the effects of NMES combination applied in addition to bicycle ergometry on mobility, functional status, muscle strength and hemodynamic responses in ICU patients.
- Trial name
- ICU-Rehab (NCT07179718)
- Testing
- neuromuscular electrical stimulation, bicycle ergometer
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Hacettepe University
Emergency Medicine, Telemedicine
Integration of the 5G-based Remote Healthcare System in Critical Care
The primary objective of this initial report is to address the following questions: Under what circumstances do clinical teams at satellite locations utilize the 5G RHS? Does the implementation of 5G RHS result in significant…
- Conditions
- Emergency Medicine, Telemedicine, Augmented Reality
- Trial name
- IT5GRHSCI (NCT06485518)
- Testing
- The 5G RHS group receiving audio-video conferencing and effective data management for decision-making via augmented reality platform RealHealthcare System.
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Sir Run Run Shaw Hospital
Critical Illness, Nurse-patient Communication
Nursing Interventions in Communication for the Critically Ill Patient: CONECTEM Programme
The aim of this quasi-experimental study is to find out whether the effectiveness of a communication intervention based on basic and assisted communication techniques improves the psycho-emotional effects of critical patients…
- Trial name
- NCT06901882
- Testing
- CONECTEM, Communication based in BCS (basic communication skills) and AAC ( aumentative alternative communicatiton)
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- University of Barcelona
Systemic Inflammatory Response Syndrome, Sepsis
Vitamin D and Critically Ill Patients
The higher rate of vitamin D deficiency is spotted among patients being hospitalized or in critical condition. Especially, vitamin D level below normal prolongs hospital stay and increases incidence of adverse prognosis and…
- Trial name
- NCT01636232
- Where
- China
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Acute Lung Injury, Acute Respiratory Distress Syndrome
Effects and Safety of Infusion of Low-Doses of Methylprednisolone in Early ALI and ARDS in Children
The purpose of this study is to investigate the effects of prolonged low-dose methylprednisolone infusion on pulmonary function (LIS and ventilation-free days), extra pulmonary organ function (PMODS score), inflammatory markers …
- Trial name
- PEDALI (NCT01757899)
- Testing
- Methylprednisolone Arm, Sterile Saline Arm
- Where
- Brazil
- Sponsor
- Universidade Federal do Rio de Janeiro
COVID-19
Therapeutic Plasmapheresis in Critically Ill Adult Patients With COVID-19 Confirmed Diagnosis
Introduction: The SARS-CoV-2 outbreak has left more than two million infected worldwide in the first four months of COVID-19 epidemic.
- Trial name
- PLASMA (NCT04480632)
- Testing
- Convalescent plasma
- Where
- Colombia
- Volunteers
- 44 people
- Sponsor
- Fundación Cardiovascular de Colombia
Critical Illness, Nurse's Role
Effect of Blood Group on the Survival Status of Intensive Care Patients
The research was planned to determine the effect of different blood groups on the 90-day survival of intensive care patients who were treated and maintained for the first time in the intensive care unit.
- Conditions
- Critical Illness, Nurse's Role, Risk Factor, Prognosis
- Trial name
- NCT04460625
- Where
- Turkey (Türkiye)
- Volunteers
- 3,114 people
- Sponsor
- Zonguldak Bulent Ecevit University
Palliative Care, Intensive Care Unit
Critical Care and Palliative Care Medicine Together in the ICU
Will earlier palliative care medicine consultation in the ICU result in decreased length of stay in the ICU and hospital, as well as, increased patient and family satisfaction.
- Conditions
- Palliative Care, Intensive Care Unit, Hospice
- Trial name
- NCT03520023
- Testing
- Palliative Care Consult
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Mayo Clinic
Critical Illness, PICS
ICU Follow-up After Prolonged Intensive Care Stay
Treatment in the intensive care unit (ICU) for more than five days often leads to chronic physical, cognitive and psychological complaints, such as post-traumatic stress disorders, muscle weakness, depression, anxiety and…
- Conditions
- Critical Illness, PICS, Post Intensive Care Syndrome
- Trial name
- PINA (NCT04186468)
- Testing
- ICU follow-up clinic
- Where
- 3 sites in Germany
- Volunteers
- 40 people
- Sponsor
- Otto-von-Guericke University Magdeburg
Critical Illness
Impact of Supplemental Parenteral Nutrition in ICU Patients on Metabolic, Inflammatory and Immune Responses
Having previously demonstrated that supplemental parenteral nutrition to complete an insufficient enteral nutrition (EN) between D4 and D8 improves outcome after critical illness, by reducing infectious complications, the present…
- Trial name
- SPN2 (NCT02022813)
- Testing
- Supplemental parenteral nutrition (SPN)
- Where
- 2 sites in Switzerland
- Volunteers
- 28 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Hyperoxemia, Cerebrovascular Circulation
HYPER MIND - Hyperoxia Effects on Cerebral Hemodynamics
This study aims to better understand how short periods of exposure to high oxygen levels affect blood flow in the brain of patients who are intubated and mechanically ventilated in the Intensive Care Unit (ICU).
- Conditions
- Hyperoxemia, Cerebrovascular Circulation, Cerebral Autoregulation, Critical Illness
- Trial name
- HYPER-MIND (NCT07377162)
- Testing
- Normobaric Hyperoxic Stimulus (NBHO)
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Erasme University Hospital
Critical Illness, Invasive Candidiasis
Pharmacokinetics of Micafungin in Critically Ill Patients
A study of micafungin in ICU versus non-ICU patients showed a significantly lower treatment success in ICU patients compared with non-ICU patients.
- Trial name
- NCT01716988
- Where
- Netherlands
- Volunteers
- 19 people
- Sponsor
- University Medical Center Groningen
Anxiety
Music for Anxiety in Critically Ill Patients
Rationale: Anxiety is common in critically ill patients, and has likely become more prevalent in the recent decade due to the imperative of the recent PADIS guidelines to use low levels of sedation and strive for wakefulness.
- Trial name
- RELACS (NCT04796389)
- Testing
- Music
- Where
- 3 sites in Netherlands
- Volunteers
- 104 people
- Sponsor
- Erasmus Medical Center
Critical Illness
Use of In-Line Filtration in Critically Ill Children
The purpose of this study is to determine whether the use of in-line filtration shows any effect on the outcome of sepsis, systemic inflammatory response syndrome (SIRS), thrombosis, or organ failure in critically ill children…
- Trial name
- NCT00209768
- Testing
- Filter: NOE96E, ELD96E, NLF1E, TNA1E
- Where
- Germany
- Volunteers
- 821 people
- Sponsor
- Hannover Medical School
Ventilator Associated Pneumonia
Implementing Oral Care Bundle on Critical Care Nurses' Practice and Mechanically Ventilated Patients' Outcomes
Oral care is a fundamental aspect of nursing that impact the health and comfort of patients over both the short and long term. Caring for very sick patients in a busy stressful environment may result in oral care having a lower…
- Trial name
- NCT05351619
- Testing
- oral care bundle implementation
- Where
- Egypt
- Volunteers
- 82 people
- Sponsor
- Mansoura University
Critical Illness, Physical Disability
Neuromuscular Electrical Stimulation (NMES) Preserves Muscle Mass in Intensive Care Unit (ICU)
Background: Low-frequency neuromuscular electrical stimulation (NMES) attenuates the loss of muscle mass of Intensive Care Unit (ICU) patients.
- Conditions
- Critical Illness, Physical Disability, Muscle Atrophy
- Trial name
- NCT05287919
- Testing
- Patients received the standard physical therapy (SPT) programme (passive mobilization) twice a day., Patients received the low-frequency neuromuscular electrical stimulation (NMES), Patients received the medium-frequency neuromuscular electrical stimulation (NMES)
- Where
- Chile
- Volunteers
- 54 people
- Sponsor
- Gabriel Nasri Marzuca-Nassr
Metabolic Acidosis, Acid-Base Imbalance
Frequency of Metabolic Acidosis in the Pediatric Intensive Care Unit
Metabolic acidosis is one of the most common acid-base disturbances encountered in critically ill children and often reflects underlying disease severity.
- Conditions
- Metabolic Acidosis, Acid-Base Imbalance, Critical Illness in Children
- Trial name
- NCT07803263
- Volunteers
- 140 people
- Sponsor
- Assiut University
Accurate Blood Glucose Monitoring in Critical Care Setting
GlucoClearTM System ICU Study
The primary purpose of this Study is evaluation of the safety and performance of the GlucoClear System (System). The primary safety objective will be assessed by: Evaluation of any serious adverse device effects upon Sensor…
- Trial name
- NCT02094859
- Where
- 2 sites in Austria, Belgium
- Volunteers
- 50 people
- Sponsor
- Edwards Lifesciences
Acute Kidney Injury, Critical Illness
Renal Resistive Index as a Predictor of Acute Renal Impairment in High-risk Patients
To study the ability of RRI, measured by bedside Doppler ultrasound, in detecting acute kidney injury in high-risk patients admitted to surgical intensive care unit, Aswan university hospital, compared with renal biomarkers and…
- Trial name
- NCT06386796
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Aswan University