Clinical trials: Critical Illness, completed
Critical Congenital Heart Disease, High Altitude
Oxygen Saturation and Perfusion Index ın Neonates at High Altitude
Congenital heart diseases are among the most common congenital anomalies and occur with an incidence of approximately 8ınd12 / 1,000 live births worldwide.
- Trial name
- NCT04290481
- Testing
- oxygen saturation and perfusion index screening
- Where
- Turkey (Türkiye)
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Critical Illness, Sepsis
Sepsis Pathophysiological & Organisational Timing
This project proposes to measure delay to admission to Intensive Care (ICU). Delays in the United Kingdom NHS are widely reported possibly because there are fewer ICU beds than in many other developed health care systems.
- Trial name
- SPOT(Light) (NCT01099813)
- Where
- United Kingdom
- Volunteers
- 15,602 people
- Sponsor
- Intensive Care National Audit & Research Centre
Critical Illness
Multi-component Family Support Tool Intervention (FST)
The National Academy of Medicine and the National Institutes of Health have called for urgent action to improve the care delivered to the nearly 1,000,000 older Americans who die in intensive care units (ICUs) annually or survive…
- Trial name
- FST (NCT05019261)
- Testing
- Multi-component Family Support Intervention
- Where
- 7 sites in United States
- Volunteers
- 1,039 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Critical Illness, Child, Only
Epidemiological Study of the Microbiota in Critically Ill Children
Objectives: To study the composition of the microbiota in critically ill children, and to know the relationship of its microbiota with clinical complications and inflammation biomarkers.
- Conditions
- Critical Illness, Child, Only, Intensive Care Unit
- Trial name
- BIOUCIP (NCT04435470)
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Universidad de Granada
Critical Illness, Children, Only
Parental Feelings About Their Child Needing a Central Line
The goal of this research project is to determine if different communication techniques during the consent process impact parental anxiety and comfort providing consent.
- Conditions
- Critical Illness, Children, Only, Stress
- Trial name
- NCT05842356
- Testing
- Communication Technique 2
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Columbia University
COVID-19
Clinical Characteristics and Outcomes of 187 Critically Ill Patients With Coronavirus Disease 2019 (COVID-19)
This case series describes the clinical characteristics, treatment and outcomes of patients with laboratory confirmed COVID-19 admitted to a 35 beds intensive care unit of a tertiary hospital in Northeast Brazil.
- Trial name
- NCT04454372
- Testing
- demographic and clinical data obtained from hospital's electronic medical record.
- Where
- Brazil
- Volunteers
- 187 people
- Sponsor
- Hospital Sao Domingos
Critical Illness, Pregnant Women
Shared Decision-Making Structured Team Model for Critical Maternal Care in OB-GYN ICU
A randomized controlled trial was conducted with 100 critically ill pregnant women admitted to our hospital's obstetrics ICU between January 2023 and December 2024.
- Trial name
- NCT06930469
- Testing
- structured team model with shared decision-making, conventional multidisciplinary resuscitation care
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Ying Wang
Aspergillosis, Influenza
Invasive Pulmonary Aspergillosis and Severe Influenza
Invasive pulmonary aspergillosis (IPA) has been reported in critically ill patients with influenza infection with a highly variable incidence between 1 to 21%.
- Conditions
- Aspergillosis, Influenza, Critical Illness
- Trial name
- ASPERGIGRIPP (NCT04232956)
- Where
- 4 sites in France
- Volunteers
- 478 people
- Sponsor
- University Hospital, Brest
Anxiety, Depression
PARTNER II: Improving Patient and Family Centered Care in Advanced Critical Illness
This is a stepped wedged randomized controlled trial comparing the PARTNER intervention with usual care in 5 Intensive Care Units.
- Trial name
- NCT02445937
- Testing
- PARTNER II
- Where
- 2 sites in United States
- Volunteers
- 848 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Critically Ill
Metabolic and Nutritional Characteristics of Long-stayer ICU Patients
The intensive care (ICU) patient population has increasing number of very long ICU stays. Long-stayers are usually defined as requiring more than 1 week of mechanical ventilation and of ICU therapy: little is know about their…
- Trial name
- Nutri-ICU-LS (NCT03938961)
- Where
- Switzerland
- Volunteers
- 205 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Critical Illness
Decision-making - the Benefit of Bedside CRP Within Ambulance Care
Patients with degreased (DGC) for ambiguous reasons receive low triage priority. Their death risk is triple. Tools are needed to identify the critically ill patients from this group. The triage used today is not effective.
- Trial name
- Q-CRP (NCT04097210)
- Testing
- POC
- Volunteers
- 110 people
- Sponsor
- Helsinki University Central Hospital
Critical Illness
CONTINUation of Enteral Nutrition Prior to Extubation Compared to Standard Care
Critically ill patients admitted to the Intensive Care Unit (ICU) often need to be connected to a breathing machine (ventilator) and are unable to eat.
- Trial name
- CONTINUE (NCT06382727)
- Testing
- EN will be continued up to extubation (EN will not be withheld prior to extubation)
- Where
- 3 sites in Australia
- Volunteers
- 60 people
- Sponsor
- Emma Ridley
Cardiac Output
Validation of Minimally Invasive Ultrasound Indicator Dilution Technique in Critically Ill Children
A novel method to measure cardiac index based on ultrasound indicator dilution technology (UIDT) has been developed by Transonic Systems Inc. (Ithaca, NY, USA).
- Trial name
- NCT00852254
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Transonic Systems Inc.
Critically Ill
Optimization of Nutritional Therapy in Mechanically Ventilated, Critically Ill Patients.
The aim of this study is to investigate whether an individualized determination of energy requirements using indirect calorimetry instead of a formula-based approach leads to an optimized nutritional support and as a consequence…
- Trial name
- ONCA (NCT03249051)
- Testing
- Indirect Calorimetry
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Hohenheim
Covid19, Cytokine Release Syndrome
Investigational Treatments for COVID-19 in Tertiary Care Hospital of Pakistan
Beyond supportive care, there are currently no proven treatment options for coronavirus disease (COVID-19) and related pneumonia, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).Investigators have seen…
- Conditions
- Covid19, Cytokine Release Syndrome, Critical Illness, ARDS
- Trial name
- NCT04492501
- Testing
- Therapeutic Plasma exchange, Convalescent Plasma, Tocilizumab
- Where
- Pakistan
- Volunteers
- 600 people
- Sponsor
- UNICEF
COVID-19
Rehabilitation in Severely Ill Inpatients With COVID-19
Inpatient rehabilitation of severe-to-critical COVID-19 patients(A longitudinal, single-center retrospective cohort)
- Trial name
- NCT05104411
- Testing
- Rehabilitative intervention
- Where
- South Korea
- Volunteers
- 37 people
- Sponsor
- Seoul National University Bundang Hospital
Fungal Prophylaxis, Candida Infection
Antifungal Prophylaxis in Intensive Care Unit (ICU) Patients
Purpose. Oral chemoprophylaxis has been advocated to reduce the incidence of Candida colonization and infection. However, Candida prophylaxis in intensive care unit (ICU) is still a matter of debate. Methods.
- Conditions
- Fungal Prophylaxis, Candida Infection, Critical Illness, Surgery
- Trial name
- NCT01495039
- Testing
- Nystatin
- Where
- Italy
- Volunteers
- 99 people
- Sponsor
- Policlinico Hospital
Critically Ill
Enhanced Protein-Energy Provision Via the Enteral Route in Critically Ill Patients
Critically ill patients are consistently underfed. Feeding protocols are standardized system tools used to guide nutrition practices, but to date have failed to improve delivery of nutrition.
- Trial name
- PEPuP (NCT01167595)
- Testing
- PEP uP Protocol
- Where
- 18 sites in United States, Canada
- Volunteers
- 1,059 people
- Sponsor
- Clinical Evaluation Research Unit at Kingston General Hospital
Malnutrition in Pregnancy, Malnutrition; Protein
Value of Early Postoperative Peptide-based Formula in Critically Ill Obstetrics on Recovery Enhancement
This is the first trial to assess the early semi-elemental postoperative formula load to meet the protein requirements in the first and second day postoperative to enhance the recovery of critically ill parturient (value on ERAS…
- Conditions
- Malnutrition in Pregnancy, Malnutrition; Protein, Postpartum Disorder, Patient Satisfaction
- Trial name
- NCT06164301
- Testing
- Elemental amino-acids
- Where
- Egypt
- Volunteers
- 83 people
- Sponsor
- Ain Shams University
Critical Illness, Pediatrics
Comparing Cardiac Output Measurements in Critically Ill Children Using USCOM and Transthoracic ECHO
The purpose of this study is to compare the accuracy and precision of two non-invasive methods of measuring cardiac output in critically ill children (<18 yrs).
- Trial name
- NCT01460329
- Testing
- Ultrasonic Cardiac Output Monitor (USCOM).
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of North Carolina, Chapel Hill
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