Clinical trials: Critical Illness, completed
Patients Are Recruited From One Thoracic and Cardiac Surgery ICU
Study of Safety and Efficacy on Neuromyopathy of Early Standing With the Assistance of Tilt Table in Critically Patients
Critically ill patients frequently develop muscle weakness due to critical illness-related acute neuropathy and/or myopathy. This disorder is associated with difficulties in weaning from mechanical ventilation, prolonged…
- Trial name
- TILT (NCT02047617)
- Testing
- the standard physiotherapy group, standing table group
- Where
- France
- Volunteers
- 145 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Critical Illness, Intensive Care Unit Syndrome
Post ICU Follow up: A Questionnaire Survey of Aftercare in Denmark
This study aims to investigate current aftercare activities in Denmark after intensive care unit (ICU) treatment. The hypothesis is that a large number of hospitals offer aftercare, and these interventions are heterogenic and…
- Trial name
- NCT02784574
- Where
- Denmark
- Volunteers
- 31 people
- Sponsor
- Zealand University Hospital
Covid19, Critical Illness
REmotely Monitored, Mobile Health-Supported High Intensity Interval Training After COVID-19 Critical Illness (REMM-HIIT-COVID-19)
REmotely Monitored, Mobile Health-Supported High Intensity Interval Training after COVID-19 critical illness (REMM-HIIT-COVID-19)
- Conditions
- Covid19, Critical Illness, High Intensity Interval Training, ICU
- Trial name
- REMMHIIT-COVID (NCT04664101)
- Testing
- REmotely Monitored, Mhealth (REMM) supported High Intensity Interval Training (HIIT), Comparator
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Duke University
Respiratory Failure
Checklists and Upright Positioning in Endotracheal Intubation of Critically Ill Patients (Check-UP) Trial
The use of a written, pre-procedure checklist and positioning the patient with the head of the bed elevated have been proposed as interventions capable of preventing complications during non-elective intubation and are used…
- Trial name
- Check-UP (NCT02497729)
- Testing
- Written Checklist, Head of Bed Up
- Where
- 5 sites in United States
- Volunteers
- 260 people
- Sponsor
- Vanderbilt University
Infection
PCT and Clinical Algorithm for Determination of Duration of Antibiotics
Patients in the ICU whose infection is resolving will be randomized to standard duration of antibiotics compared to duration determined by a combination of a procalcitonin value and a simple evaluation of clinical status.
- Trial name
- NCT01572831
- Testing
- PCT and clinical algorithm for stopping abx
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Fraser Health
Critical Illness, Dysbiosis
Influences of High-fiber, Organic Whole-food Formula on the Gut Microbiome in Critically Ill Children
This study evaluates the effects of either Pediasure or Nourish formulas on the gastrointestinal microbiome in critically-ill children. Patients will be randomized to received either Pediasure or Nourish.
- Conditions
- Critical Illness, Dysbiosis, Pediatric ALL
- Trial name
- NCT03414775
- Testing
- Nourish, Pediasure
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Pittsburgh
Pharmacokinetics
Nomograms for Optimization of Amikacin First Dose in Critically Ill Patients Using a Population Pharmacokinetics Model
The aim of this study is to elaborate nomograms to optimize amikacine first dosing in critically ill patients, using a population pharmacokinetics model elaborated with multicentric data.
- Trial name
- PIC-AMI (NCT03683511)
- Where
- France
- Volunteers
- 138 people
- Sponsor
- Nantes University Hospital
Critical Illness
Early Rehabilitation in Critically Ill Children Pilot Study
Critically ill patients are often confined to bedrest, because of the nature of their illness. However, it has now been shown that prolonged bedrest and immobility, particularly in critically ill adults and children, can lead to…
- Trial name
- WeeHab in PCCU (NCT01531816)
- Testing
- Early Rehabilitation intervention
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McMaster University
Effect of RBC Transfusions on Cerebral Oxygen Saturation
Monitoring the Effect of Red Blood Cell Transfusion on Cerebral Oxygen Saturation With Near Infrared Spectroscopy (NIRS) in Critically Ill Patients
Critically ill patients are frequently transfused with red blood cell (RBC) units with the predominant intention to increase arterial oxygen content and thus oxygen delivery to the tissues.
- Trial name
- NCT02232412
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Critical Illness, Intensive Care Unit
Effect of Continuous Versus Cyclic Daytime Enteral Nutrition on Circadian Rhythms in Critical Illness
Disruption of circadian rhythms is frequently observed in patients in the intensive care unit (ICU) and is associated with worse clinical outcomes.
- Conditions
- Critical Illness, Intensive Care Unit, Circadian Rhythm, Sleep
- Trial name
- CIRCLES (NCT05795881)
- Testing
- Cyclic daytime enteral nutrition
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Leiden University Medical Center
Dietary Supplements, Intensive Care Unit
Vitamin D Supplementation in Intensive Care Unit Patients
A randomized controlled trial is designed to investigate the safety and clinical efficacy of a mega dose of VD in patients admitted in intensive care unit (ICU).
- Conditions
- Dietary Supplements, Intensive Care Unit, Vitamin D Deficiency, Vitamin D Toxicity
- Trial name
- NCT04915963
- Testing
- Vitamin D supplementation
- Volunteers
- 340 people
- Sponsor
- Association Tunisienne d'Etude & de Recherche sur l'Athérosclérose
Therapeutic Drug Monitoring, Critical Illness
Pharmacokinetic of Posaconazole in Critically Ill Patients
The posaconazole pharmacokinetic in critically ill patients will be studied in a prospective, non-interventional, monocentric observational trial.
- Trial name
- NCT05275179
- Testing
- Posaconazole Therapeutic Drug Monitoring
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Cancer, Critical Illness
Cancer Patients Treated With Immunotherapy in Intensive Care Unit
This work aims to describe the characteristics and methods of management of patients suffering from a solid tumor treated with immunotherapy admitted to intensive care.
- Conditions
- Cancer, Critical Illness, Immunotherapy
- Trial name
- IMMUNO-REA (NCT03357861)
- Where
- 2 sites in Belgium, France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Grenoble
Corona Virus Infection
Efficacy of Inhaled Nitroglycerin in Moderate to Critically Ill COVID-19 Patients
In current analysis moderate to severely ill Covid-19 infected patients will be nebulized with nitroglycerin, and they will be compared with the standard nebulization
- Trial name
- NCT04686760
- Testing
- Nitroglycerin
- Where
- Pakistan
- Volunteers
- 278 people
- Sponsor
- University of Lahore
Psycho-educational, Anxiety
The Effect of Bibliotherapy Administered During the Preoperative Period on Vital Signs, Anxiety, and Coping With Illness in Adolescent Patients
This study aimed to evaluate the effects of bibliotherapy administered to adolescent patients in the preoperative period on vital signs, anxiety levels, and coping attitudes using a pretest-posttest controlled experimental…
- Conditions
- Psycho-educational, Anxiety, Illness, Critical
- Trial name
- Bibliotherapy (NCT07126054)
- Testing
- bibliotherapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul Medipol University Hospital
Ventilator-associated Pneumonia
Study of Biotene OralBalance Gel for Oral Care in Critically-Ill Mechanically Ventilated Neonates
The goal of this pilot study is to test the hypothesis that mechanically ventilated infants receiving Biotene OralBalance® gel for oral care would have a reduced intubation time compared to infants receiving oral care placebo.
- Trial name
- NCT01314742
- Testing
- Biotene OralBalance® gel, Sterile Water moisten cotton tipped applicator
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- Wake Forest University Health Sciences
Hypotension
Cardiac Output Monitoring in Critically Ill Patient Undergoing Intubation
Collect hemodynamic data, such as heart rate, blood pressure, and cardiac output to help understand the effect of pre and post intubation.
- Trial name
- NCT03525743
- Testing
- NICOM (Non invasive cardiac output monitor)
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Mayo Clinic
Critical Illness, Antibiotic-associated Diarrhea
Probiotics For The Prevention of Antibiotics Associated Diarrhea in the Pediatric Intensive Care Unit
The goal of this prospective trial is to learn about lactobacillus use in critically ill pediatric patients. The main question[s] it aims to answer are: Is lactobacillus GG effective in preventing antibiotic associated diarrhea…
- Trial name
- NCT06109740
- Testing
- lactobacillus GG
- Volunteers
- 21 people
- Sponsor
- University of South Alabama
Survival After IPA, Risk Factors for IPA
Diagnosis of Invasive Pulmonary Aspergillosis (IPA) in Critically Ill Patients
Invasive pulmonary aspergillosis (IPA) is difficult to diagnose and remains a cause of high morbidity and mortality in critically ill patients in the ICU.
- Trial name
- DipA (NCT01866020)
- Where
- Germany
- Volunteers
- 85 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Withdrawal Syndrome, Iatrogenic Disease
AduLt iatrogEnic withdRawal sTudy in the ICU (ALERT-ICU)
Withdrawal from opioids and sedatives administered for medical purposes (i.e. iatrogenic withdrawal) often goes unrecognized in the critically ill, but its prevalence is high.
- Trial name
- NCT04422808
- Where
- United States
- Volunteers
- 2,437 people
- Sponsor
- Wilkes University
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