Clinical trials: Critically Ill Intensive Care Unit Patients
Post Intensive Care Unit Syndrome, Intensive Care Unit Acquired Weakness
Intensive Care Unit Recovery
Survival rates of patients with critical illness have increased due to improved facilities and treatment methods in the intensive care unit (ICU).
- Conditions
- Post Intensive Care Unit Syndrome, Intensive Care Unit Acquired Weakness, Critical Illness
- Trial name
- ICU-RE (NCT04154995)
- Testing
- Venipuncture, Ultrasound Quadriceps Muscles
- Where
- Netherlands
- Volunteers
- 81 people
- Sponsor
- Frisius Medisch Centrum
Underdosing of Aminoglycosides, Critical Illness
An International Survey on Aminoglycoside Practices in Critically Ill Patients: AMINO III Survey
This is an international observational cohort study on current aminoglycoside practices in intensive care units. Clinical and demographic data, dosing and therapeutic drug monitoring data will be collected during the first week…
- Trial name
- NCT02850029
- Testing
- Observational study, no intervention
- Where
- 85 sites in Australia, Chile and 3 more
- Volunteers
- 964 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Anemia, Mechanical Ventilation
Anemia and Duration of Mechanical Ventilation
In mechanically ventilated patients in intensive care unit, anemia is commonly seen and it is probably associated with adverse outcomes including mortality.
- Conditions
- Anemia, Mechanical Ventilation, Critically Ill, Intensive Care Unit
- Trial name
- NCT05382065
- Where
- Thailand
- Volunteers
- 236 people
- Sponsor
- Mahidol University
Critical Illness, Social Isolation
Reducing Isolation and Feeling of Loneliness During Critical Illness
The trial is a pilot-randomized trial testing feasibility and limited-efficacy of delivering social engagement using technologic strategies to reduce periods of social isolation.
- Conditions
- Critical Illness, Social Isolation, Anxiety, Depression
- Trial name
- SOCIAL (NCT05537311)
- Testing
- Social Engagement
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Kirby Mayer
ICU Acquired Weakness
Diagnosing Intensive Care Unit (ICU) Acquired Weakness
The goal of this study is to develop a non-invasive test to diagnose intensive care unit (ICU) acquired weakness that can be administered to both responsive and non-responsive patients.
- Trial name
- NCT04166630
- Testing
- Clinical Electrical Stimulator
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Emory University
Critical Illness, Surgery
Gastric US in ICU Patient
This is a case series study using gastric ultrasound in critically ill patients to quantify gastric residual volumes to compare the efficacy of different NPO protocols.
- Conditions
- Critical Illness, Surgery, Aspiration Pneumonia
- Trial name
- NCT05526105
- Testing
- Gastric Ultrasound
- Where
- United States
- Sponsor
- Dartmouth-Hitchcock Medical Center
Critical Illness
Economics of Diarrhoea in Intensive Care Unit
Enteral nutrition (EN) is the first choice route for nutritional support in ICU patients with a functioning digestive tract. Nevertheless, EN alone is often associated with digestive intolerance, including diarrhoea.
- Trial name
- NCT01922570
- Testing
- nutrition
- Where
- Switzerland
- Volunteers
- 305 people
- Sponsor
- University Hospital, Geneva
Initial Phase of Severe Sepsis and Septic Shock
Population Pharmacokinetics and Monte Carlo Dosing Simulations of Meropenem During the Early Phase of Severe Sepsis and Septic Shock in Critically Ill Patients in Intensive Care Units
This is a prospective, noncomparative study to assess the pharmacodynamics of meropenem during early phase of severe sepsis and septic shock in critically ill patients in an intensive care unit.
- Trial name
- NCT02213796
- Testing
- Meropenem
- Where
- Thailand
- Volunteers
- 9 people
- Sponsor
- Sutep Jaruratanasirikul
Covid-19, Family Members
Impact of Covid-19 Restrictive Measure on Anxiety, Depression and PTSD for Relatives of ICU Patients
To limit the pandemic Covid-19 infection, the French government imposed a closure of all Intensive Care Unit (ICU). The family's visitations are prohibited during active Covid -19 pandemic in 2020 and in 2021.
- Conditions
- Covid-19, Family Members, Critical Illness
- Trial name
- HAD-Covid (NCT04430049)
- Testing
- Covid ICU containment measures
- Where
- 11 sites in France
- Volunteers
- 811 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pneumonia, Resistant Pneumonia
Flexible Bronchoscopy in Resistant Pneumonia in PICU
Pneumonia remains a leading cause of morbidity and mortality among critically ill children admitted to Pediatric Intensive Care Units (PICUs).
- Conditions
- Pneumonia, Resistant Pneumonia, Resistant Pneumonia in Critically Ill Pedaitric Patients
- Trial name
- FFP-RP PICU (NCT07421440)
- Testing
- Flexible fiberoptic bronchoscopy with bronchoalveolar lavage (BAL)
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansour Gomaa Mohammed Saleh
Sepsis, ARDS
Microcirculation and Oxidative Stress in Critical Ill Patients in Surgical Intensive Care Unit
As medicine advances, many lives can be saved in the intensive care unit. However, when multiple organ failure occurs, the mortality rate of patients increases dramatically.
- Conditions
- Sepsis, ARDS, Liver Failure, Renal Failure
- Trial name
- NCT00808691
- Testing
- Critical care
- Where
- Taiwan
- Volunteers
- 124 people
- Sponsor
- National Taiwan University Hospital
Critically Ill
Continuous Temperature Measurement by Thermal Imaging Camera
This study explores the significance of body temperature monitoring in hospitalized patients, particularly in critical care environments.
- Trial name
- TermoCamUCI (NCT06256978)
- Volunteers
- 224 people
- Sponsor
- Universidad Europea de Madrid
Critical Illness, Transitions of Care
Evaluating the Effectiveness of an Electronic Medical Transfer Tool to Improve Communication During Transfers From ICU
The transfer of patients from the intensive care unit (ICU) to a medical or surgical hospital ward is a particularly high risk transfer that may expose patients to complications or adverse events if there are communication…
- Trial name
- NCT03590002
- Testing
- Electronic ICU Medical Transfer Tool
- Where
- 4 sites in Canada
- Volunteers
- 1,751 people
- Sponsor
- Henry T. Stelfox, MD PhD
Critically Ill, Malnutrition
Promotion of Oesophageal Motility to Prevent Regurgitation and Enhance Nutrition Intake in ICU Patients.
Early enteral feeding is a key component of the management of critically ill patients receiving mechanical ventilation. However, enteral feeding has been associated with serious complications such as gastro-esophageal reflux…
- Trial name
- PROPEL (NCT02515123)
- Testing
- E-Motion System
- Where
- 11 sites in Canada
- Volunteers
- 158 people
- Sponsor
- E-Motion Medical Ltd.
Covid-19, Critical Illness
MIcrovascular Dysfunction in CRitically Ill cOVID-19 Patients
Microcirculatory dysfunction appears to play a key role in the development of organ failure leading to the death of patients with coronavirus disease 2019 (Covid-19).
- Conditions
- Covid-19, Critical Illness, Hemodynamics, SARS-CoV Infection
- Trial name
- MICROVID (NCT04819802)
- Testing
- Measurement of sublingual microcirculation, Plasma sampling
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronavirus Infections, Critical Illness
Comparison of Clinical Outcome Among Vaccinated and Unvaccinated Coronavirus Disease Patients in Critical Care Unit.
Corona virus disease has been a pandemic since its beginning. The problem has scaled to break health care system of multiple countries.
- Trial name
- NCT05331742
- Testing
- Vaccine
- Volunteers
- 200 people
- Sponsor
- Civil Service Hospital of Nepal
Obesity, Obesity With Complications
Prevalence, Determinants and Consequences of Dyspnea During Weaning in Critically Ill Obese Patients
ICU patients encounter numerous discomforts, with dyspnea (the sensation of breathlessness) being among the most distressing and impactful.
- Conditions
- Obesity, Obesity With Complications, Weaning From Mechanical Ventilation in Care Unit, Dyspnea
- Trial name
- WEAN OBESE (NCT06867354)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Enteral Nutrition, Enteral Nutrition Feeding
Stepwise Enteral Nutritional Algorithm and Patient Outcomes in Pediatric Intensive Care Units
The aim of the study to evaluate the effectiveness and patient's outcome after implementing enteral nutrition algorithm designed to achieve optimal enteral nutrition delivery in the pediatric intensive care unit and to evaluate…
- Conditions
- Enteral Nutrition, Enteral Nutrition Feeding, Enteral Nutrition Intolerance in Critically Ill Patients
- Trial name
- NCT07307027
- Testing
- Stepwise Enteral Nutritional Algorithm
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Critically Ill
24 Hour Intensivist Coverage in the Medical Intensive Care Unit
The Hospital of the University of Pennsylvania's Medical ICU (MICU) is implementing a model of 24-hour intensivist staffing in September 2011.
- Trial name
- NCT01434823
- Testing
- Nocturnal coverage
- Where
- United States
- Volunteers
- 1,609 people
- Sponsor
- University of Pennsylvania
Alcohol Use Disorder, Critically Ill
Brief Intervention for ICU Patients with Alcohol Use Disorders
Patients non-electively admitted to intensive care units (ICUs) will be screened for eligibility. The investigators will include adult patients with risk level alcohol use, defined by AUDIT-C score (>5 for females, >6 for males).
- Trial name
- ICU-BI (NCT03047577)
- Testing
- Brief intervention
- Where
- 3 sites in Finland
- Volunteers
- 237 people
- Sponsor
- University of Helsinki