Clinical trials: Critically Ill Patient
Shock
High Dose Vitamin C in the Critically Ill Patient
The purpose of this study is to determine the effectiveness of high doses of Vitamin C in critically ill patients.
- Trial name
- VitC (NCT01587963)
- Testing
- Ascorbic Acid, Ringers Lactate or Normal Saline
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Rutgers, The State University of New Jersey
Critical Illness
LOGIC-Insulin Algorithm-guided Versus Nurse-directed Blood Glucose Control During Critical Illness
The LOGIC-Insulin computerized software algorithm will be compared with a nurse-directed protocol, both targeting a blood glucose level of 80-110 mg/dL, in critically ill patients
- Trial name
- LOGIC-1 (NCT01420302)
- Testing
- Nurse directed, LOGIC-Insulin
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- Greet Van den Berghe
Acute Respiratory Failure
Effect of Thiamine on Oxygen Utilization (VO2) in Critical Illness
The objective of this study is to determine the effect of thiamine therapy on oxygen consumption in critically-ill patients. The investigators will evaluate this by measuring VO2 before and after thiamine administration in…
- Trial name
- VO2 (NCT01462279)
- Testing
- Thiamine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Beth Israel Deaconess Medical Center
Critical Care, Walking
Validity of an Actigraph Accelerometer Following Critical Illness
This study will determine whether an Actigraph GT3X accelerometer can identify body position and quantify step count in a ward based population recovering from critical illness.
- Conditions
- Critical Care, Walking, Posture
- Trial name
- NCT03295630
- Testing
- Accelerometer
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Septic Shock, Sepsis
Phenylephrine Versus Norepinephrine for Septic Shock in Critically Ill Patients
Septic shock is a condition that is marked by severe infection causing hypotension requiring vasopressors to maintain adequate perfusion to vital organs.
- Conditions
- Septic Shock, Sepsis, Shock, Tachycardia
- Trial name
- NCT02203630
- Testing
- Phenylephrine, Norepinephrine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Vanderbilt University Medical Center
Chronic Disease, Neoplasm Metastasis
Facilitating Communication Study
This study is a randomized clinical trial of an intervention to improve outcomes for patients and their family by using ICU nurse facilitators to support, model, and teach communication strategies that enable patients and their…
- Conditions
- Chronic Disease, Neoplasm Metastasis, Lung Neoplasm, Pulmonary Disease, Chronic Obstructive
- Trial name
- FCS2 (NCT03721952)
- Testing
- Facilitator-Based Intervention
- Where
- 3 sites in United States
- Volunteers
- 977 people
- Sponsor
- University of Washington
Anemia
Use of Pediatric Size Phlebotomy Tubes in Adult Critically Ill Patients to Reduce Red Blood Cell Transfusions
This study will evaluate the hypothesis that the use of pediatric size phlebotomy tubes reduces red blood cell (RBC) transfusions in adult intensive care unit (ICU) patients compared with the use of adult size tubes.
- Trial name
- NCT03286465
- Testing
- Pediatric phlebotomy tubes, Adult phlebotomy tubes
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The University of Texas Health Science Center, Houston
SARS-CoV 2
Efficacy of Tocilizumab on Patients With COVID-19
This is a randomized, double blind, multi-center study to evaluate the effects of tocilizumab compared to placebo on patient outcomes in participants with confirmed SARS-CoV-2 infection and evidence of systemic inflammation.
- Trial name
- NCT04356937
- Testing
- Tocilizumab
- Where
- 3 sites in United States
- Volunteers
- 243 people
- Sponsor
- Massachusetts General Hospital
Chronic Respiratory Failure, Critical Illness Myopathy
Electric Muscle Stimulation for Patients With Chronic Respiratory Failure
Background: After mechanical ventilation, 5-20% of patients with acute respiratory failure would depend on ventilator support more than 14 days because of critical-illness weakness and their underlying diseases such as heart…
- Trial name
- NCT01930643
- Testing
- EMS
- Where
- Taiwan
- Volunteers
- 13 people
- Sponsor
- Mackay Memorial Hospital
Critical Illness
Does Acetylsalicylic Acid Reduce the Mortality of Patients Admitted to an Intensive Care Unit
Platelets play a central part not just in homeostasis and thrombosis as the primary effector cells, but they are also key cells in the regulation of the immunological response to various stressors.
- Trial name
- NCT02285153
- Testing
- Acetylsalicylic acid lysinate, 0.9% sodium-chloride solution
- Where
- Austria
- Volunteers
- 15 people
- Sponsor
- Medical University of Vienna