Clinical trials: Crowding, active
Malocclusion, Class I/II, Crowding
A Comparative Study Between Modified Miniscrew-Assisted Rapid Palatal Expander And Modified Rapid Palatal Expander in Molar Distalization Using Cone- Beam Computed Tomography
Comparative study between modified miniscrew-assisted rapid palatal expander and modified rapid palatal expander in molar distalization using CBCT.
- Conditions
- Malocclusion, Class I/II, Crowding, Maxillary First Molar Distalization
- Trial name
- MIDPAC (NCT07038902)
- Testing
- Group A: Modified Miniscrew-Assisted Rapid Palatal Expander (MARPE), Group B: Modified Rapid Palatal Expander (RPE)
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Non-small Cell Lung Cancer Stage III
Chemoradiotherapy With Surgery Followed by Consolidation Durvalumab
Lung cancer presents a significant treatment challenge, particularly in the heterogeneous stage III NSCLC patient population. While chemotherapy combined with high-dose radiotherapy (60 Gy in 30 fractions of 2 Gy once daily) is…
- Trial name
- CROWD (NCT06908070)
- Testing
- Consolidation durvalumab
- Where
- Netherlands
- Volunteers
- 38 people
- Sponsor
- Idris Bahce
Crowding of Anterior Maxillary Teeth, Orthodontics, Interceptive
Interceptive Maxillary Expansion to Relief Anterior Crowding in the Mixed Dentition
The goal of this clinical trial is to compare if it is better to treat severe anterior crowding in the early mixed dentition then later in the permanent dentition in children with anterior crowding of the upper teeth.
- Conditions
- Crowding of Anterior Maxillary Teeth, Orthodontics, Interceptive, Orthodontics, Corrective, Palatal Expansion Technique
- Trial name
- NCT06187337
- Testing
- Maxillary expansion device
- Where
- 4 sites in Italy, Sweden
- Volunteers
- 60 people
- Sponsor
- Region Örebro County
Angle Class I Maloclussion, Dental Crowding
Orthodontic Treatment Outcomes of Self Ligating System Compared to Clear Aligner System
This study is a multi-center, prospective, parallel-group randomized controlled trial designed to compare the orthodontic treatment outcomes of a passive self-ligating bracket system (Damon Ultima) versus a clear aligner system.
- Trial name
- NCT07638397
- Testing
- self ligating bracket, Clear aligner
- Where
- Iraq
- Volunteers
- 42 people
- Sponsor
- University of Baghdad
Effectiveness of the I-arch System
Clinical Performance of the I-arch System During the Initial Stage of Orthodontic Treatment
The goal of this clinical trial is to learn if the I-arch system works to align the moderately misaligned teeth in patients seeking orthodontic treatment.
- Trial name
- NCT07264127
- Testing
- The use of 0.016×0.014 copper nickel titanium arch wire during the alignment stage., Use of 0.014- then 0.016-inch heat-activated nickel titanium arch wire during the alignment stage.
- Where
- Iraq
- Volunteers
- 34 people
- Sponsor
- Tabark H. Omran
Crowding of Anterior Mandibular Teeth
Evaluating the Efficacy of Micro-Osteoperforations Technique on the Orthodontic Tooth Movement Acceleration in Moderate Mandibular Anterior Crowding Cases Treated With Clear Aligners
Patients with moderate mandibular anterior crowding will be treated in this study. The efficacy of micro-osteoperforations technique by special drill in accelerating orthodontic tooth movement during clear aligners therapy will…
- Trial name
- NCT05492773
- Testing
- Micro-osteoperforations Technique, Active comparater
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hama University
Colorectal Cancer
A Community Population Screening Cohort Study Based on Polygene Methylation Detection for Colorectal Cancer in Yangzhou
This is a cross-sectional cohort study based on community population jointly developed by Northern Jiangsu People's Hospital and Shanghai Kunyuan Biological Technology Co., LTD.
- Trial name
- NCT05336539
- Where
- 2 sites in China
- Volunteers
- 80,000 people, healthy volunteers welcome
- Sponsor
- Singlera Genomics Inc.
Acute Disease, Sepsis
Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine
Research in acute care faces many challenges, including enrollment challenges, legal limitations in data sharing, limited funding, and lack of singular ownership of the domain of acute care.
- Conditions
- Acute Disease, Sepsis, Pneumonia, Frailty
- Trial name
- Acutelines (NCT04615065)
- Where
- Netherlands
- Volunteers
- 35,000 people
- Sponsor
- University Medical Center Groningen
Skeletal Class I Non-extraction Patients With Dental Crowding
Evaluation of Dentoalveolar Changes of Clear Aligners Versus Fixed Orthodontic Appliances on Skeletal Class I Non-extraction Patients With Dental Crowding
To evaluate dentoalveolar changes of clear aligners versus fixed orthodontic appliances on skeletal class I non-extraction patients with dental crowding.
- Trial name
- NCT07090746
- Testing
- Clear aligner, Fixed orthodontic appliance
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Mansoura University
Malocclusion of Anterior Teeth
Effects of Laser Therapy and Vitamin D Pills on Braces Tooth Movement: A Random Controlled Study
This clinical trial aims to evaluate the efficacy of low-level laser therapy (LLLT) in conjunction with oral vitamin D3 supplementation in accelerating orthodontic tooth movement in adults with crowded mandibular anterior teeth…
- Trial name
- LLLT (NCT07286474)
- Testing
- Cholecalciferol (Vit D3), Low-Level Laser Therapy, Fixed Orthodontic Appliance
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Angle Class I Malocclusion, Dental Crowding
Clinical Performance of Direct-Printed Versus Thermoformed Aligners
The goal of this study is to evaluate and compare the clinical effectiveness of in-office directly 3D-printed clear aligners versus conventional multilayered thermoformed aligners.
- Conditions
- Angle Class I Malocclusion, Dental Crowding, Tooth Spacing
- Trial name
- NCT07637227
- Testing
- Direct-Printed Aligner, Thermoformed aligner
- Where
- 3 sites in Iraq
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Dental Crowding,Interproximal Enamel Reduction, Malocclusion, Angle's Class
Accuracy and Periodontal Outcomes of Three Interproximal Enamel Reduction Techniques During Clear Aligner Therapy
This randomized controlled clinical trial will compare three commonly used interproximal enamel reduction (IPR) techniques during clear aligner therapy in adult patients.
- Conditions
- Dental Crowding,Interproximal Enamel Reduction, Malocclusion, Angle's Class, Periodontal Diseases
- Trial name
- NCT07377825
- Testing
- Manual Arm, Motor Driven Arm, Abrasive Arm
- Where
- Saudi Arabia
- Volunteers
- 75 people
- Sponsor
- Riyadh Elm University
Cancer
A Crowd Sourcing Platform for Patients With Cancer
All4Cure aims to accelerate learning about cancer by sharing medical information and research results from cancer patients with fellow cancer patients, oncologists, and scientists on the All4Cure website with the hope that…
- Trial name
- NCT03530826
- Testing
- No intervention
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- All4Cure
Crowding, Tooth, Orthodontic
Orthodontic Treatment in Adolescents With Crowding and Displaced Teeth
The purpose is to fill knowledge gaps identified for orthodontic treatment using a novel study design that has not been implemented in the dental field or in orthodontics.
- Trial name
- CROWDIT (NCT05664282)
- Testing
- Damon self-ligating brackets, Victory self-ligating brackets
- Volunteers
- 131 people
- Sponsor
- Malmö University
Dental Crowding
Early Orthodontic Treatment of Dental Crowding
Aim of the study is to compare treatment duration and effects of orthodontic treatment of dental crowding between treatments started at different stages of mixed dentition phase.
- Trial name
- NCT04756843
- Testing
- Quad-helix
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- University of Helsinki
Dental Crowding, Dental Occlusion, Traumatic
Exploration of the Utility of Dental-dedicated MRI for Dentistry
This description observational research is comparative in design, that is comparing existing standard clinical dental images, not obtained in this study, to test (i.e., ddMRI) images.
- Conditions
- Dental Crowding, Dental Occlusion, Traumatic, Endodontic Disease, Orthodontic Treatment
- Trial name
- NCT06948162
- Testing
- dental-dedicated MRI (ddMRI)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Emergency Department Overcrowding
ED Post-Discharge Digital Follow-Up: A Communication Comparison
Emergency department overcrowding is a universal phenomenon associated with worse patient outcomes and a negative impact on healthcare teams.
- Trial name
- NCT07447674
- Testing
- Standard Telephone Follow-Up, Enhanced Digital Communication Strategy
- Volunteers
- 466 people
- Sponsor
- Hospital Israelita Albert Einstein
Crowding of Teeth, Malocclusion; Displaced Teeth
Timing, Trajectories and Prediction in Severe Dental Crowding: The Create SPACE (cSPACE)
Dental crowding is the most common malocclusion affecting up to 45% of the population and represents one of the leading reasons for seeking orthodontic treatment.
- Conditions
- Crowding of Teeth, Malocclusion; Displaced Teeth, Malocclusion in Children
- Trial name
- cSPACE (NCT07911176)
- Testing
- Early first premolar extraction with observation, Early first premolar extraction with planned fixed orthodontic treatment
- Volunteers
- 300 people
- Sponsor
- Vastra Gotaland Region
Crowding, Tooth, Gingival Diseases
Gingival Phenotype and Dental Crowding in Pediatric Patients
The periodontal phenotype influences treatment outcomes across dental specialties, as tissues of different thickness respond differently to chemical, bacterial, and mechanical insults.
- Trial name
- BIOTIPO_PEDO (NCT07205172)
- Testing
- Orthodontic and periodontal analysis
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Dental Crowding, Gingival Recession
Evaluating the Clinical Efficacy of Collagen Scaffold (Ossix VOLUMAX) With Piezo-Surgical Decortication in Enhancing Orthodontic Treatment Outcomes: A Randomized Controlled Trial
Recent advances in orthodontic treatment have explored various materials to enhance treatment efficacy, particularly focusing on collagen scaffolds.
- Conditions
- Dental Crowding, Gingival Recession, Thin Phenotype
- Trial name
- NCT07097714
- Testing
- Piezocision with ribose cross-linked collagen matrix (Ossix® Volumax), control
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- NMSI DENTMASTER