Clinical trials: Cryoballoon Ablation
Atrial Fibrillation
Lesion Formation With Pulsed Field Versus Cryobaloon Ablation as Assessed by Cardiac Magnetic Resoncance
This randomised study will compare pulsed field ablation and cryoballoon ablation with respect to ablation lesion quality as assessed by late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) at 3 months…
- Trial name
- PULSED-ICE-CMR (NCT06220006)
- Testing
- Pulmonary vein isolation
- Where
- Spain
- Volunteers
- 104 people
- Sponsor
- Hospital Clinic of Barcelona
Atrial Fibrillation
Renal Nerve Denervation After Pulmonary Vein Isolation for Persistent Atrial Fibrillation
Atrial fibrillation (AF) is the most common arrhythmia and it is associated with significant morbidity and mortality. Electrical isolation of the pulmonary vein (PVI) by radiofrequency energy or cryoablation has been shown to be…
- Trial name
- NCT03246568
- Testing
- Renal Nerve Denervation, Pulmonary vein isolation
- Where
- Hong Kong
- Volunteers
- 3 people
- Sponsor
- Chinese University of Hong Kong
Atrial Fibrillation
Cryoballoon Isolation of Superior Vena Cava in Paroxysmal Atrial Fibrillation
There is still unresolved question whether isolation of superior vena cava (SVC) in conjunction to conventional pulmonary vein isolation (PVI) improves outcomes in the treatment of paroxysmal atrial fibrillation.
- Trial name
- CISPAF (NCT05081310)
- Testing
- superior vena cava isolation, pulmonary vein isolation
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- University of Zagreb
Atrial Fibrillation
Cryoballoon Ablation in Patients With Longstanding Persistent Atrial Fibrillation
Prospective and explorative clinical study. The objective is to assess the clinical efficacy of pulmonary vein isolation using the Arctic Front Advance cryoballoon in patients with longstanding persistent atrial fibrillation (AF)…
- Trial name
- CRYO-LPAF (NCT02294929)
- Testing
- Atrial fibrillation ablation
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Uppsala University Hospital
Atrial Fibrillation
Cryoballoon vs. Rhythmia Guided Ablation for Recurrent AFib
The purpose of this research is to evaluate whether cryoballoon ablation vs. radiofrequency ablation guided by high-fidelity mapping (Rhythmia) is the best treatment strategy to perform repeat ablation for recurrent atrial…
- Trial name
- NCT03811795
- Testing
- ECG monitoring with a Kardia Mobile monitor
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Valley Health System
Paroxysmal Atrial Fibrillation
Balloon Cryoablation Without Contrast
Pulmonary vein isolation using cryoballoon ablation is well established method for the treatment of atrial fibrillation. As a rule, cryoenergy delivery is preceded by documenting the full vein occlusion.
- Trial name
- CRY-OUT-CAT (NCT04344743)
- Testing
- Cryoballoon ablation without contrast
- Where
- 2 sites in Poland
- Volunteers
- 50 people
- Sponsor
- Medicover Hospital
Barrett's Esophagus
Efficacy of CryoBalloon Focal Ablation System on Human Esophageal Barrett's Epithelium
The purpose of this study is to assess the efficacy and performance of the C2 Focal Cryoablation System in patients with BE.
- Trial name
- NCT02249975
- Testing
- C2 CryoBalloon Focal Ablation System
- Where
- 2 sites in Netherlands
- Volunteers
- 50 people
- Sponsor
- Pentax Medical
Atrial Fibrillation
All Inclusive Kodex - EPD Study
This is a post-market, prospective, observational study to evaluate the accuracy of KODEX 3D-imaging. The research study will collect pre-operative and post-operative cardiac imaging data from adult arrhythmia patients who are…
- Trial name
- NCT05489445
- Testing
- KODEX - EPD
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Arizona
Persistent Atrial Fibrillation
Persistent Atrial Fibrillation Cryoballoon Ablation
Patients with persistent irregular heartbeats also called persistent atrial fibrillation usually have a lower probability of curing their arrhythmia with ablation with heat called radiofrequency then those with paroxysmal atrial…
- Trial name
- PAFCA (NCT02166723)
- Testing
- Cryoballoon Ablation
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Staten Island University Hospital
Atrial Fibrillation
Effect of Cryoballoon and RF Ablation on Left Atrial Function
120 consecutive patients with paroxysmal AF, slated for PV isolation, will be randomly assigned to RF or cryoballoon ablation (in a 1:2 allocation scheme).
- Trial name
- CryoLAEF (NCT02611869)
- Testing
- Cryoballoon, RF ablation
- Where
- 2 sites in Greece
- Volunteers
- 120 people
- Sponsor
- G.Gennimatas General Hospital
Atrial Fibrillation, Atrial Fibrillation (Paroxysmal)
Wide-Antral Pulmonary Vein Isolation in Atrial Fibrillation Ablation with a Single-shot Technique (WIDER-PVI)
The WIDER PVI study is a multicentre randomized clinical trial to compare the efficacy of antral versus extended antral PVI in patients with paroxysmal or persistent AF undergoing this procedure using a cryoablation balloon…
- Trial name
- WIDER-PVI (NCT06698159)
- Testing
- Cryoablation with cryoballoon 28 mm, Cryoablation with cryoballoon 31 mm
- Where
- 17 sites in Italy, Spain
- Volunteers
- 440 people
- Sponsor
- Hospital Universitario 12 de Octubre
Barrett's Esophagus
Cryo Balloon for Residual Barrett's Esophagus
This study is being done to see if treating residual Barrett's Esophagus after previously having undergone Radiofrequency ablation or Endoscopic Mucosal resection can be eliminated with focal cryotherapy.
- Trial name
- Cryoballoon (NCT02230410)
- Testing
- CryoBalloon Focal Ablation
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Mayo Clinic