Clinical trials: Cryopreservation
Facial Defect
Autologous Fresh Fat Grafting Followed by Autologous Cryopreserved Fat Grafting
The goal of this clinical trial is to validate the safety and effectiveness of a two-stage approach for minimally invasive craniofacial soft tissue reconstruction using autologous fat grafting in wounded service members and…
- Trial name
- NCT06747715
- Testing
- Serial Fat Grafting Fresh followed by Cryopreserved Fat
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Pittsburgh
Procedure-Related Pain, Acute Pain
Virtual Reality Intervention to Reduce Pain in Women Undergoing Elective Oocyte Cryopreservation
This randomized controlled study evaluates whether exposure to relaxing virtual reality (VR) scenery prior to oocyte retrieval can reduce pain in women undergoing elective oocyte cryopreservation.
- Trial name
- OPU-VR (NCT07484815)
- Testing
- Virtual reality relaxation intervention, Standard Care Control
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hadassah Medical Organization
Infertility
Frozen-thawed Embryo Transfer (FTET) Cycle Follow-up Protocol (P06031)
The purpose of this follow-up study is to collect the outcome and safety of FTET cycles after the embryos are cryopreserved in P06029 (NCT01144416).
- Trial name
- NCT01146418
- Testing
- Corifollitropin alfa, recFSH (follitropin beta)
- Volunteers
- 307 people
- Sponsor
- Organon and Co
Breast Cancer Female
Combining Interventions of Fertility Preservation to Mitigate Fertility Loss After Breast Cancer
This clinical prospective randomised controlled trial will evaluate the impact of an ovarian biopsy on the oocyte yield after controlled ovarian stimulation before chemotherapy in view of breast cancer.
- Trial name
- Coimbra (NCT04586686)
- Testing
- Ovarian biopsy via laparoscopy, Transvaginal oocyte retrieval
- Where
- 2 sites in Belgium
- Volunteers
- 41 people
- Sponsor
- Universitair Ziekenhuis Brussel
Cancer, Autoimmune Diseases
Ovarian Tissue Cryopreservation for Fertility Preservation
The goal of this observational study is to learn about fertility preservation for pre-pubertal, peri-pubertal, and adult participants that are unable to pursue clinical standard of care fertility preservation such as egg (oocyte)…
- Trial name
- NCT05875155
- Testing
- Infectious Disease Labwork, Fertility-Based Labwork
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Pittsburgh
Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia in Remission
Infusion of Off-the-Shelf Expanded Cord Blood Cells to Augment Cord Blood Transplant in Patients With Hematologic Malignancies
This phase II trial is studying the safety and potential efficacy of infusing non-human leukocyte antigen matched ex vivo expanded cord blood progenitors with one or two unmanipulated umbilical cord blood units for…
- Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q)
- Trial name
- NCT01175785
- Testing
- umbilical cord blood transplantation, fludarabine phosphate, cyclophosphamide
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Nohla Therapeutics, Inc.
Fertilization in Vitro, Preservation of Supernumerary Embryos
Day 3 Embryo Cryopreservation: Metabolic and Viability Analysis
Embryo preservation through freezing plays a significant role in human assisted reproduction. It provides an opportunity for patients to have more than one attempt following an ovarian stimulation cycle, thereby decreasing the…
- Trial name
- NCT00608010
- Testing
- Vitrification, Slow freezing
- Where
- Turkey (Türkiye)
- Volunteers
- 186 people
- Sponsor
- V.K.V. American Hospital, Istanbul
Infertility, Female, Infertility
Use of Clomiphene Citrate as an Inhibitor of Ovulation in an Oocyte Cryopreservation Cycle
In vitro fertilization (IVF) has helped countless couples conceive where they otherwise were unable, but does come at a significant cost.
- Trial name
- CCOI (NCT05866068)
- Testing
- Clomiphene
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Neil Chappell
HIV Infections
Effects of Storage on Lactate in Blood Samples
The purpose of this study is to determine whether laboratory storage of samples affects the amount of lactate over 3 years. Lactate is a natural substance normally present in the body.
- Trial name
- NCT00011050
- Where
- 3 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)