Clinical trials: Culture
Vaccine Hesitancy
Culturally and Linguistically Appropriate Vaccine Education
The goal of this clinical trial is to test the effectiveness of culturally tailored social media campaigns and WhatsApp-based vaccine training for healthcare workers in increasing childhood routine and HPV vaccine confidence and…
- Trial name
- CLAVE (NCT06186206)
- Testing
- Social media interventions for vaccine uptake
- Where
- Guatemala
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dementia Caregiver
Dementia Family Caregiver Study
The proposed study will test a 3-month, community health worker (CHW) delivered home visit, culturally and language-appropriate intervention for ethnic and underserved dementia family caregivers of persons with dementia (PWD)…
- Trial name
- NCT04894006
- Testing
- Community Health Worker (CHW) Home Visit Intervention, Attention Control Group with WIoT Technology, Usual Care
- Where
- United States
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
COVID-19
RADx-UP CDCC Rapid Research Pilot Program "Culturally-relevant Community Connections (C3) to Increase COVID-19 Testing
The purpose of this study is to identify barriers and facilitators to COVID testing among members of the Black/African American community.
- Trial name
- NCT05918952
- Testing
- Covid-19 Antibody Test, Short Clip videos
- Where
- United States
- Volunteers
- 327 people, healthy volunteers welcome
- Sponsor
- Duke University
Infertility, Female
Evaluation of Different Culture Media for in Vitro Fertilization
Under in vivo conditions, human gametes and embryos are exposed to fluids in the fallopian tubes, where fertilization occurs, and in the uterus, the site of embryonic implantation.
- Trial name
- NCT05676515
- Testing
- culture media
- Where
- Brazil
- Volunteers
- 48 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Tuberculosis
Tuberculosis Treatment Shortening Trial
Tuberculosis (TB) is a serious infection that can affect the lungs and other parts of the body. The usual way to treat TB is to take 4 medicines by mouth every day for 2 months, then take 2 of the same medicines for 4 more…
- Trial name
- NCT00130247
- Testing
- Ethambutol, Isoniazid, Pyrazinamide
- Where
- 3 sites in Brazil, Philippines and 1 more
- Volunteers
- 394 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
NSCLC (Non-small Cell Lung Cancer), Metastatic NSCLC - Non-Small Cell Lung Cancer
Observational Lung Trial to Collect Tissue to Train and Validate a Live Tumor Diagnostic Platform (ELEPHAS-01)
The primary objective of this study is to determine the ex-vivo prognostic accuracy of the Cybrid live tumor diagnostic platform using in-vivo RECIST 1.1 as the reference method.
- Trial name
- ELEPHAS-01 (NCT05478538)
- Testing
- Core Needle, Forceps, or Punch Biopsy
- Where
- 7 sites in United States
- Volunteers
- 200 people
- Sponsor
- Elephas
Safety
Intensive Care Nurses' Training Package on the Safety Culture of Geriatric Patients
This study aims to determine the effect of intensive care nurses' training package on the safety culture of critically ill geriatric patients.
- Trial name
- NCT05910918
- Testing
- Intensive Care Nurses' Training Package
- Where
- 2 sites in Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Parapneumonic Effusion
Metagenomic Study in Parapneumonic Effusion
Objective: To identify known and unknown bacterial pathogens in patients with pleural infections using a combination of conventional culture and next-generation sequencing approaches.
- Trial name
- NCT05394220
- Testing
- 16S rRNA gene amplicon sequencing
- Where
- Hong Kong
- Volunteers
- 115 people
- Sponsor
- Chinese University of Hong Kong
Bacteremia
Clinical Performance and Reproducibility of the Accelerate PhenoTest™ Blood Culture (BC) Kit With New Antibiotic Wave I Updates
This is a performance and reproducibility study to validate new or updated antimicrobials on the Accelerate PhenoTest™ BC kit. The data from this study will be used to support the submission to the FDA for clearance in the US and…
- Trial name
- NCT04295915
- Testing
- Specimens that meet inclusion criteria
- Where
- 3 sites in United States
- Volunteers
- 731 people, healthy volunteers welcome
- Sponsor
- Accelerate Diagnostics, Inc.
Preterm Birth, Pediatric Cancer
eHealth as an Aid for Facilitating and Supporting Self-management in Families With Long-term Childhood Illness
The overall aim is twofold: 1) to stretch the borderline regarding the present knowledge of clinical and economic cost-effectiveness of eHealth as an aid for facilitating and supporting self-management in families with long-term…
- Conditions
- Preterm Birth, Pediatric Cancer, Hirschsprung Disease, Congenital Malformation
- Trial name
- eChildHealth (NCT04150120)
- Testing
- e-health device with application, Mobile phone text messaging, early detection of cerebral palsy using a mobile phone application
- Where
- 7 sites in Denmark, Ethiopia and 1 more
- Volunteers
- 720 people
- Sponsor
- Lund University
Complex Post-Traumatic Stress Disorder
Complex-Posttraumatic Stress Disorder - Cultural Adaptation of a Therapeutic Manual and Development of a Culture-specific Diagnostic Module for Refugee Populations in Switzerland (Pilot Trial)
In January 2022, the World Health Organization (WHO) launched the 11th edition of the International Classification of Diseases (ICD-11).
- Trial name
- NCT05917613
- Testing
- Enhanced Skills Training in Affective and Interpersonal Regulation combined with Modified Prolonged Exposure (ESTAIR/MPE)
- Where
- 2 sites in Switzerland
- Volunteers
- 24 people
- Sponsor
- Eva Heim
Bacteriuria, Urinary Tract Infection
Restricted Reporting for Positive Urine Cultures
Asymptomatic bacteriuria (AB) is a condition in which bacteria are detected in urine culture without urinary symptoms. The inappropriate use of antibiotic treatment for AB selects bacterial flora to express resistance mutations.
- Trial name
- NCT02797613
- Testing
- Restricted Reporting
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- Memorial University of Newfoundland
Obesity, Obesity, Childhood
FACILITY: Feeding the fAmiLy: the Intergenerational approaCh to fIght obesiTY
The FACILITY STUDY is aimed at evaluating maternal and children social, cultural, economic and lifestyle-related risk factors for the development of childhood overweight, obesity and early adiposity rebound (EAR).
- Conditions
- Obesity, Obesity, Childhood, Obesity, Maternal, Overweight
- Trial name
- FACILITY (NCT06164340)
- Volunteers
- 269 people
- Sponsor
- Buzzi Children's Hospital
Pancreatic Ductal Adenocarcinoma
A Clinical Study to Evaluated Which Number of Passes of EUS-FNB is Better for Culturing Primary Cells of PDAC
The Aim of this study is to investigate the amount of tissue required for the successful culture of primary cells from human-derived pancreatic ductal adenocarcinoma which obtained by endoscopic ultrasound-guided fine-needle…
- Trial name
- NCT04794140
- Testing
- different number of passes
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Erythema Migrans
Inflammatory Responses in Solitary and Multiple Erythema Migrans
The investigators will evaluate differences in host immune responses (levels of cytokines and chemokines, representative of innate, Th1, and Th17 immune responses) in acute sera from adult patients with solitary or multiple…
- Trial name
- NCT03980015
- Testing
- antibiotic treatment
- Where
- Slovenia
- Volunteers
- 134 people
- Sponsor
- University Medical Centre Ljubljana
Advanced Cancer, Metastatic Cancer
Prediction of Drug Response Using an Ex Vivo Organ Culture (EVOC) on Fresh Human Tumour Samples From Metastatic Patients
The primary objective of this study is to determine how sensitive and specific the Curesponse Ex Vivo Organ Culture (EVOC) model is at predicting a patient's clinical response to a specific cancer therapy.
- Trial name
- CURESPONSE (NCT04599608)
- Volunteers
- 248 people
- Sponsor
- Imperial College London
Infertility
Study of Free DNA Content of Embryo Culture Medium as a Non-Invasive Tool for Embryo Assessment
Study of Cell Free DNA Content of Human Embryo Culture Medium as a Non-Invasive Tool for Embryo Assessment in intra cytoplasmic sperm injection Treatment Cycles.
- Trial name
- NCT02480491
- Testing
- measuring cell freeDNA
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sadat City University
Influenza, Human, Infections
Study to Evaluate Safety and Immunogenicity of Different Priming and Booster Regimens With Adjuvanted H5N8 and/or H5N6 Influenza Vaccine in Adults
This Phase 2, randomized, observer-blind clinical study is evaluating 3 different priming and booster regimens with MF59-adjuvanted H5N8 and/or H5N6 cell culture-derived influenza vaccine (aH5N8c; aH5N6c).
- Conditions
- Influenza, Human, Infections, Respiratory Tract Infections, Virus Diseases
- Trial name
- NCT05874713
- Testing
- aH5N8c on Day 1, aH5N6c on Day 1, aH5N8c on Day 22
- Where
- 9 sites in United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Seqirus
Safety Issues
Model for Safety Culture by Empowering the Family at Home: a Mixed-methods Study Protocol
Background: The elderly are a vulnerable group for health problems as they age. Safe care is essential when caring for the elderly at home because adverse events can happen there, such as falls, pressure ulcers, injuries, or…
- Trial name
- NCT05487482
- Testing
- Ageing Safe from the Risk (ASRi) Model of safety culture
- Where
- Indonesia
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
Obsessive-Compulsive Disorder, Cognitive Behavioral Therapy
Brief Culturally Adapted CBT for OCD
The purpose aims to assess the efficacy of Brief Culturally Adapted Cognitive Behaviour Therapy (Ca-CBT) for the treatment of Obsessive Compulsive Disorder (OCD).
- Trial name
- NCT07232823
- Testing
- Brief culturally adapted cognitive behaviour therapy (CaCBT)
- Where
- Pakistan
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Pakistan Association of Cognitive Therapists