Clinical trials: Cumulative Irritation
Pain, Healthy Volunteers
A Study to Learn About Whether BAYH006689 Causes Skin Irritation When Applied as a Topical Gel in Healthy Participants
Researchers are looking for a better way to treat muscle and joint pains. Researchers have seen that medicines which help reduce pain and inflammation could be safer when applied directly to the skin, called topical application…
- Trial name
- NCT06511973
- Testing
- Naproxen (BAYH006689), A solution of 0.9% Saline, A solution of 0.2% SLS
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Bayer
Skin Sensitisation
HRIPT for Collagen Dressing
The objectives of this study are to determine by repetitive epidermal contact, the primary or cumulative irritation and the allergic contact sensitization potential of the ColActive Plus Collagen Matrix Dressing, under maximized…
- Trial name
- NCT06283173
- Testing
- ColActive Plus Collagen Matrix Dressing
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Covalon Technologies Inc.
Allergy, Irritation
Cumulative Irritation Patch Test
A Cumulative Patch Test with a Challenge Phase is a test devised to ascertain if a chemical agent or agents have the potential to cause contact irritation or contact allergy in the skin.
- Conditions
- Allergy, Irritation, Sensitization
- Trial name
- NCT01842711
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Chattem, Inc.
Sunburn
Dermal Irritation, Sensitization and Cumulative Irritation Potential of 6% Bemotrizinol
The purpose of this clinical trial is to evaluate the dermal safety of Bemotrizinol (6%).
- Trial name
- NCT05260359
- Testing
- 6% Bemotrizinol (BEMT) in a basic sunscreen oil formulation, 6% Bemotrizinol (BEMT) dispersion in petrolatum, Sunscreen oil vehicle with 10% ethanol as penetration enhancer without BEMT
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Hypersensitivity
Study to Determine Skin Irritation Potential of an Antifungal Cream Containing Trolamine After Repeated Skin Application (Cumulative Irritation Patch Test)
In this study researchers want to study the potential skin reaction after repeated application of an antifungal cream containing trolamine.
- Trial name
- NCT04531813
- Testing
- Butenafine HCl 1% (BAY1896425), Positive Control-Sodium lauryl sulfate (SLS), Negative Control
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bayer
Psoriasis Vulgaris
Combined Cumulative Irritation Potential and Repeat Insult Patch Test of LEO 90100
The purpose of this study is to determine the skin irritation potential and sensitisation potential of LEO 90100 and the vehicle after repeated applications on the skin of healthy subjects.
- Trial name
- NCT01935869
- Testing
- LEO 90100, Vehicle, Petrolatum ointment
- Where
- France
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- LEO Pharma
Healthy
Dermal Cumulative Irritant Patch Study
A 21-Day, Randomized, Controlled Study to Evaluate the Skin Irritation Potential of FMX-101 in Healthy Volunteers Using a Cumulative Irritant Patch Test Design
- Trial name
- NCT04064125
- Testing
- FMX-101
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Vyne Therapeutics Inc.
Surgery
Irritation and Sensitization of Chlorhexidine Gluconate (CHG) Cloth
Evaluating the irritation properties of CHG cloth. Some Subjects will also have the product applied to see if they become sensitized to repeated applications.
- Trial name
- NCT02224625
- Testing
- 2% CHG Cloth solution, Vehicle Cloth, Active Comparator
- Where
- United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Medline Industries
Surgical Site Infection
Safety Study to Evaluate the Cumulative Irritation Potential of Topically Applied ZuraPrep™ and ZuraPrep™ Without IPA
This is a safety study to determine the cumulative skin irritation potential of ZuraPrep™ and ZuraPrep™ without Isopropyl Alcohol after repetitive patch applications to skin of human subjects.
- Trial name
- NCT02160574
- Testing
- ChloraPrep, 0.1% Sodium Lauryl Sulfate, 0.9% Physiological Saline
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Smoking Cessation
Cumulative Skin Irritation Potential of a New 25 mg Nicotine Patch
An investigation on the cumulative skin irritation potential of a newly developed 25 mg nicotine patch. Evaluation of skin irritation of a newly developed 25 mg nicotine transdermal patch
- Trial name
- NCT00967174
- Testing
- Nicotine Patch, SLS Comparator Patch
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- McNeil AB
Onychomycosis
Cumulative Irritation Test
The purpose of this study is to determine the cumulative irritation potential of the products listed by the Sponsor.
- Trial name
- NCT00680095
- Testing
- AN2690, AN2690 Solution, Vehicle, Sodium Lauryl Sulfate, 0.5%
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Pfizer