Clinical trials: Cutaneous Scars, open to volunteers
Burn Scar, Burn Wound
Post-Operative Use of FS2 to Mitigate Scarring in Burn Patients
The goal of this study is to see how an ingredient called kynurenic acid (which we named "FS2") affects scar formation in people with burn injuries that need skin graft surgery.
- Trial name
- NCT06807021
- Testing
- IP1 control cream (Vehicle base), IP2 - 0.5% w/w FS2
- Where
- 2 sites in Canada
- Volunteers
- 70 people
- Sponsor
- Birch BioMed Inc
Scar
Tissue-engineered Skin Graft Repair of Autologous Scar Dermal Scaffolds
Hypertrophic scar is an inevitable outcome of wound repair. It affects the appearance and some scar contracture often leads to joint dysfunction.Patients have low quality of life, long treatment cycle, heavy social burden and…
- Trial name
- NCT04389164
- Testing
- Tissue-engineered skin grafts of autologous scar dermal scaffolds
- Where
- China
- Volunteers
- 226 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Breast Ptosis, Mammaplasty
Autologous Free Dermal Graft Support in Superior Pedicle Vertical Scar Reduction Mammaplasty
The goal of this observational study is to learn whether using an autologous free dermal graft during breast reduction surgery helps maintain lower breast pole shape over time in women undergoing primary bilateral reduction…
- Conditions
- Breast Ptosis, Mammaplasty, Lower Pole Elongation, Postoperative Breast Pseudoptosis
- Trial name
- NCT07657962
- Testing
- Autologous Free Dermal Graft Support
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Cumhuriyet University Hospital
Scarring
Aesthetic Outcome of Intra-dermal Versus Transcutaneous Purse-string Closure
The purpose of this study is to determine whether intra-dermal versus transcutaneous purse-string closures have similar scar cosmesis and post-operative complications.
- Trial name
- NCT06448481
- Testing
- Intra-dermal purse-string closure, Transcutaneous purse-string closure
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of California, Davis
Gout Initiating Urate-loweringUrate-lowering Therapy, Gout Arthritis
HLA-B*58:01-Guided Therapy for Gout: Effectiveness, Safety, and Cost-Effectiveness
Severe cutaneous adverse reactions (SCARs), such as Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) and drug reaction with eosinophilia and systemic symptoms (DRESS), are rare but life-threatening complications that…
- Conditions
- Gout Initiating Urate-loweringUrate-lowering Therapy, Gout Arthritis, Gout and Hyperuricemia
- Trial name
- HLA-SCREEN (NCT07369622)
- Testing
- HLA-B*58:01 Genotyping, Allopurinol Tablet, Febuxostat
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Haiphong University of Medicine and Pharmacy
Lip, Cleft, Lip Scar
Evaluation of a HA Dermal Filler in the Treatment of Lip Deformity
Early postnatal repair of cleft lip and palate aims at the development of the child through reconstruction of the face soon after birth.
- Trial name
- FENTHA (NCT05825170)
- Testing
- FASY L
- Where
- 3 sites in France
- Volunteers
- 20 people
- Sponsor
- Symatese
Stevens-Johnson Syndrome, Lyell Syndrome
Drug Reactions Sampling (COLLECTIONTOXIDERMIES)
Intro: Dermatology department of Henri Mondor Hospital (Creteil, France), is a reference center for toxic bullous diseases and severe cutaneous drug reactions (Stevens-Johnson syndrome (SJS), Lyell syndrome (toxic epidermal…
- Conditions
- Stevens-Johnson Syndrome, Lyell Syndrome, Drug Reactions, AGEP
- Trial name
- NCT03659227
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Standardized Cutaneous Wounds (Punch-biopsy Wounds)
Topical GHK-Cu Gel for Acute Skin Wound Healing
This study will evaluate whether a topical gel containing GHK-Cu (a copper(II)-peptide complex) can safely speed up healing of small, standardized skin wounds in healthy adults compared with a matching vehicle gel.
- Trial name
- CuHeal (NCT07437586)
- Testing
- GHK-Cu Gel (Copper(II)-peptide complex)
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hudson Biotech