Clinical trials: Cutaneous Wound
Diabetes Mellitus, Ulcer Foot
Examining the Effectiveness of DermGEN™ in the Treatment of Diabetic Foot Ulcers in First Nations People
The study will examine the effectiveness of a decellularized dermal matrix (i.e., DermGEN™) in improving wound healing, quality of life and associated costs of treatment of DFUs in First Nations people living in the Northwestern…
- Conditions
- Diabetes Mellitus, Ulcer Foot, Ulcer Healing, Diabetic Foot Ulcer
- Trial name
- NCT05251480
- Testing
- Standard of Care, DermGEN™
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- DeCell Technologies Inc.
Blister, Wound of Skin
Safety, Tolerability, and Pharmacokinetics of Ascending Topical Doses of TCP-25 Applied to Epidermal Suction Blister Wounds, Non-Healing Leg Ulcers and Patients With Dystrophic Epidermolysis Bullosa.
This is a three-part, Phase I, first-in-human study designed to evaluate the safety, tolerability, and potential systemic exposure of multiple topical doses of TCP-25.
- Conditions
- Blister, Wound of Skin, Epidermolysis Bullosa, Varicose Ulcer of Lower Limb
- Trial name
- NCT05378997
- Where
- Sweden
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Xinnate AB
COVID 19
Acral Cutaneous Thrombotic Vasculopathy and Covid-19 Infection
Spectrum of skin lesions may arise during Covid-19 virus infection. It includes non-specific urticaria, aphtoids lesions, but also acrosyndromes, in particular suggestive of chilblains.
- Trial name
- NCT04361786
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Montpellier
Melanoma, Skin Cancer
The Aim of This Study is to Demonstrat That Vacuum-assisted Closure Versus Conventional Wound Closure Enables to Diminish Local Complications After Lymph Node Dissection in Patients With Metastatic Skin Tumors
In this study, we compared a negative pressure wound therapy, versus a conventional dressing in order to evaluate the most efficient wound therapy closure after axillary and inguinal lymph nodes dissections in the management of…
- Conditions
- Melanoma, Skin Cancer, Epidermoid Carcinoma, Neuroendocrine Carcinoma
- Trial name
- NCT04583605
- Testing
- PREVENA
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Central Hospital, Nancy, France
Wound Cosmesis
Comparison of Traditional Superficial Cutaneous Sutures Versus Steri-Strip Coaptive Film in Layered Dermatologic Closures
The purpose of this study is to compare the cosmetic outcome between buried intradermal and superficial cutaneous suture closures versus buried intradermal sutureand superficial Steri-Strip closures in the bilayered repair of…
- Trial name
- NCT01938586
- Testing
- Steri-Strip, Superficial sutures
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Burn Injury, Acute Wound
Cutaneous Microcirculation After Remote Ischemic Preconditioning
In plastic and reconstructive surgery, treatment strategies of second-degree burns, superficial wounds and chronic wounds aim at reducing infection and improving microcirculation.
- Conditions
- Burn Injury, Acute Wound, Chronic Wound
- Trial name
- NCT02417805
- Testing
- Intervention: Remote Ischemic Preconditioning
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital Schleswig-Holstein
Orbital Floor Fractures, Surgical Wound Closure Techniques
Subciliary Closure in Orbital Fracture
Title: Subciliary Closure in Orbital Fractures: A Comparison Between Cutaneous and Cutaneo-Periosteal Sutures Brief Summary: This prospective, experimental, and comparative study evaluated the impact of two different subciliary…
- Conditions
- Orbital Floor Fractures, Surgical Wound Closure Techniques, Subciliary Surgical Approach, Postoperative Complications in Maxillofacial Surgery
- Trial name
- NCT07042763
- Testing
- Cutaneous Suture, Periosteal Suture
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Instituto Mexicano del Seguro Social
Wound Closure Techniques
Undermining During Cutaneous Wound Closure
The purpose of this study is to determine whether undermining during cutaneous surgery improves scar cosmesis compared to wound closure without undermining.
- Trial name
- NCT02289859
- Testing
- Wound Closure with Undermining, Wound Closure without Undermining
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Wound of Skin
Adipose-derived Stem Cells to Treat Chronic Wounds.
The goal of this study is to determine whether autologous, adipose-derived regenerative cells improve the healing of chronic wounds.
- Trial name
- NCT05797688
- Testing
- The Celution System
- Where
- United States
- Sponsor
- Winthrop University Hospital
CTCL
StrataCTX® as a Steroid Sparing Device
The purpose is to determine if StrataCTX® can be used as a steroid sparing agent for the treatment of cutaneous reactions related to, cutaneous T Cell lymphoma (CTCL) and chemotherapy/immunotherapy treatments than the current…
- Trial name
- NCT04087629
- Testing
- StrataCTX® gel
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Columbia University
Intertrochanteric Fractures
Blocks for Intertrochanteric Fracture Repair Surgery
This single-center open label study compares the outcomes of surgical repair of intratrochanteric fracture under general anesthetic or peripheral nerve blocks.
- Trial name
- NCT04470115
- Testing
- General anesthesia, Regional anesthesia- femoral and lateral femoral cutaneous nerve blocks
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Military Institute od Medicine National Research Institute
Laceration, Incision
Optilene® Suture Material for Dermal Sutures
In this non-interventional study, Optilene® suture will be evaluated for skin closure in adult patients.
- Trial name
- OPTIDERMAL (NCT05240248)
- Where
- Spain
- Volunteers
- 172 people
- Sponsor
- Aesculap AG
Wound Healing, Acute Skin Wounds
Study of LUT017 Gel to Improve Healing of Skin Wounds After Removal of Benign Lesions in Healthy Adults
This is a Phase 1 research study evaluating the safety and potential benefits of a topical gel called LUT017 in helping skin wounds heal after minor skin procedures.
- Trial name
- NCT07463378
- Testing
- LUT017,Topical BRAF inhibitor
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Antoni Ribas
Bone Loss, Implant Site Injury
Tunnel Access for Lateral Alveolar Ridge Augmentation
Minimally invasive procedures with the tunnel technique have been suggested to decrease patient post-operative discomfort and morbidity in oral bone regeneration.
- Trial name
- NCT05475730
- Testing
- bone and soft tissue augmentation
- Where
- Italy
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- D'Albis Dental
Prolapse; Female, Prolapse Genital
Transvaginal Human Acellular Dermal Matrix for Prolapse Treatment
This is a randomised study in which we compare the effectiveness of three different procedures in mending symptomatic anterior and apical prolapse in patients who are candidates to receive surgery.
- Conditions
- Prolapse; Female, Prolapse Genital, Prolapse Uterovaginal
- Trial name
- NCT06404931
- Testing
- Vaginal hysterectomy plus matrix reinforcement and sacrospinous fixation with Anchorsure® device, Vaginal hysterectomy plus anterior colporrhaphy, Vaginal hysterectomy plus sacrospinous fixation with Anchorsure® device
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Mutua de Terrassa
Scarring
Aesthetic Outcome of Intra-dermal Versus Transcutaneous Purse-string Closure
The purpose of this study is to determine whether intra-dermal versus transcutaneous purse-string closures have similar scar cosmesis and post-operative complications.
- Trial name
- NCT06448481
- Testing
- Intra-dermal purse-string closure, Transcutaneous purse-string closure
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of California, Davis