Clinical trials: Cystocele
Stress Urinary Incontinence
Effect of Cystocele Repair With Trans Obturator Tape VS. Trans Obturator Tape Alone on Stress Urinary Incontinence.
The goal of this interventional study is to compare the effect of Concurrent cystocele repair and trans obturator tape (TOT) and TOT alone in a sample of Iraqi Female participants with diagnosed stress urinary incontinence and…
- Trial name
- NCT06044987
- Testing
- Trans Obturator Tape Procedure (TOT), Cystocele Repair
- Where
- Iraq
- Volunteers
- 98 people
- Sponsor
- Al-Mustafa University College
Colorectal Disorders, Prolapse
Biological OviTex Versus Synthetic Graft in Robotic Prolapse Surgery
This prospective study aims to assess the efficacy of the OviTex 1S permanent mesh in pelvic floor surgery in comparison with the current standard polypropylene mesh.
- Conditions
- Colorectal Disorders, Prolapse, Prolapse Rectal, Prolapse Genital
- Trial name
- ProTex (NCT06430931)
- Testing
- Minimal invasive abdominal prolapse surgery using Polypropylene mesh, Minimal invasive abdominal prolapse surgery using OviTex 1S permanent mesh
- Where
- Netherlands
- Volunteers
- 184 people
- Sponsor
- Meander Medical Center
Cystocele, Rectocele
Clinical Performance of the GYNECARE PROLIFT + M* Pelvic Floor Repair System as a Device for Pelvic Organ Prolapse
The purpose of this study is to evaluate the clinical performance of the PROLIFT system with a new lighter-weight mesh in repair of vaginal prolapse.
- Conditions
- Cystocele, Rectocele, Enterocele
- Trial name
- NCT00833001
- Testing
- GYNECARE PROLIFT+M* Pelvic Floor Repair System
- Where
- 8 sites in Belgium, France and 2 more
- Volunteers
- 126 people
- Sponsor
- Ethicon, Inc.
Pelvic Organ Prolapse, Uterine Prolapse
Efficacy Study of Vaginal Mesh for Prolapse
The primary aim of this double-blind, randomized clinical trial (RCT) is to test the hypothesis that the addition of a standardized technique of interpositional synthetic polypropylene mesh placement improves the one-year outcome…
- Conditions
- Pelvic Organ Prolapse, Uterine Prolapse, Vaginal Prolapse, Cystocele
- Trial name
- VAMP (NCT00475540)
- Testing
- synthetic monofilament polypropylene mesh
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Medstar Health Research Institute
Cystocele
Lower Urinary Tract Symptoms Screening Questionnaire
The purpose of this study is to determine the validity of a screening tool which has been designed to detect the presence or absence of lower urinary tract symptoms in the general female population.
- Trial name
- LUTS-2 (NCT01616810)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Pelvic Organ Prolapse Vaginal Surgery, Pelvic Organ Prolapse (POP)
Effectiveness of Perineorrhaphy in Pelvic Organ Prolapse Surgery
This is an observational registry-based study of long-term outcome after vaginal native tissue repair for pelvic organ prolapse designed to emulate a pragmatic open-label two-arm trial for which patients, in whom perineorrhaphy…
- Trial name
- PINPOPS (NCT07006129)
- Testing
- Perineorrhaphy, No perineorrhaphy
- Where
- Sweden
- Volunteers
- 40,646 people
- Sponsor
- Lund University
Pelvic Organ Prolapse, Uterovaginal Prolapse
Absorbable Suture vs Permanent Suture in Sacrospinous Ligament Suspension
Sacrospinous ligament suspension (SSLS) was first described in 1958. It is commonly performed for correction of apical prolapse. A combination of delayed absorbable and/or permanent sutures are commonly used for the procedure.
- Conditions
- Pelvic Organ Prolapse, Uterovaginal Prolapse, Vaginal Vault Prolapse, Cystocele
- Trial name
- NCT05688059
- Testing
- Absorbable Suture and Permanent Suture
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Atlantic Health System
Urethra Issue, Pelvic Organ Prolapse
Lessons on Urethral Lidocaine in Urodynamics
This trial will assess whether use of intraurethral 2% lidocaine jelly meaningfully impacts sensation during filling (i.e., a change of more than 25% of first sensation, first desire to void, strong desire to void, or maximum…
- Conditions
- Urethra Issue, Pelvic Organ Prolapse, Urinary Incontinence, Vaginal Vault Prolapse
- Trial name
- LULU (NCT04038099)
- Testing
- Water-Based Vaginal Lubricant, lidocaine topical
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Texas Southwestern Medical Center
Pelvic Organ Prolapse, Cystocele
Study Comparing Transobturator Cystocele vs. Anterior Vaginal RepairS
Surgical correction of the prolapse in the anterior compartment remains one of the major challenges in urogynecology. Paravaginal defect in level II of vaginal fixation results in the majority of cystoceles.
- Conditions
- Pelvic Organ Prolapse, Cystocele, Cystocele and Incomplete Uterovaginal Prolapse
- Trial name
- STARS (NCT05602246)
- Testing
- Transobturator cystocele repair, Anterior colporrhaphy
- Where
- 8 sites in Czechia, Slovakia
- Volunteers
- 592 people
- Sponsor
- Charles University, Czech Republic
Anterior Vaginal Wall Prolapse
Mesh Repair of Anterior Vaginal Wall Prolapse
The purpose of this study is to determine whether reenforcement with polypropylen mesh compared with traditional anterior colporrhaphy for anterior vaginal wall prolapse results in fewer recurrences.
- Trial name
- NCT00420225
- Testing
- Low-weight prolypropylene mesh
- Where
- Finland
- Volunteers
- 202 people
- Sponsor
- Tampere University
Pelvic Organ Prolapse
The ELEGANT Trial: Elevate Transvaginal Mesh vs. Anterior Colporrhaphy
This study is designed to compare the safety and efficacy of a commercially available mesh kit used for surgical repair of anterior vaginal wall prolapse with traditional suture repair surgery.
- Trial name
- NCT01497171
- Testing
- Elevate Mesh, Anterior Colporrhaphy
- Where
- 6 sites in United States, Germany
- Volunteers
- 5 people
- Sponsor
- Emanuel Trabuco
Cystocele
Transvaginal Versus Transobturator Paravaginal Repair
Clinical trial comparing the new technique for paravaginal repair versus the traditional technique
- Trial name
- NCT03489902
- Testing
- Transobturator Paravaginal Repair, traditional transvaginal Paravaginal Repair
- Volunteers
- 40 people
- Sponsor
- Ain Shams Maternity Hospital
Disability Physical, Urinary Incontinence
Transversus Abdominis and Pelvic Floor Muscle Strengthening Exercise Program In Patients With Grade 1 Cystocele
Cystocele, a protrusion of the bladder, happens while the bladder descends into the vagina. There are more than one underlying causes for the development of cystocele ensuing in weak point of the muscles and the connective tissue…
- Conditions
- Disability Physical, Urinary Incontinence, Prolapse
- Trial name
- NCT05474495
- Testing
- Pelvic floor muscle training, Transverse abdominas strength training
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Pelvic Organ Prolapse
Restorelle® Mesh Versus Native Tissue Repair for Prolapse
The purpose of this study is to collect information on the safety and effectiveness of Restorelle Direct Fix mesh and the surgical procedure to implant Restorelle.
- Trial name
- NCT02162615
- Testing
- Restorelle Direct Fix A, Restorelle Direct Fix P, Native Tissue Repair Anterior
- Where
- 49 sites in United States, Australia and 4 more
- Volunteers
- 810 people
- Sponsor
- Coloplast A/S
Uterine Prolapse, Bladder Diseases
Pelvic Floor Muscle Training (PFMT) in Treatment and Prevention of POP (POP Study)
Background: The pelvic floor muscles (PFM) are located inside the pelvis, surrounding the urethra, vagina and rectum. They provide structural support for the pelvic organs.
- Conditions
- Uterine Prolapse, Bladder Diseases, Cystocele, Rectocele
- Trial name
- NCT00271297
- Testing
- Pelvic floor muscle training
- Where
- Norway
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Pelvic Organ Prolapse, Cystocele
Laparoscopic Three-dimensional Versus Two-dimensional Sacral Colpopexy and Paravaginal Repair
Compare operative times and complications of sacral colpopexy and paravaginal repair between two-dimensional and three-dimensional laparoscopic systems.
- Trial name
- NCT02258230
- Testing
- 3D mode of the 3D Laparoscopic Video System, 2D mode of the 3D Laparoscopic Video System
- Where
- 2 sites in United States
- Volunteers
- 194 people
- Sponsor
- Olympus Corporation of the Americas
Prolapse
Surgical Study Comparing 2 Procedures for the Treatment of a Dropped Bladder
The purpose of this study is to determine whether vaginal repair or abdominal repair is the procedure of choice for the surgical management of a prolapsed bladder.
- Trial name
- NCT00271102
- Testing
- anterior vaginal repair (colporrhaphy), abdominal paravaginal defect repair
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Geisinger Clinic
Pelvic Organ Prolapse
Comparison of Suturing Technique Types on Pubocervical Fascia at Colpographhy Anterior for Cystocele Repair
Anterior colporrhaphy is the commonly performed surgery for pelvic organ prolapse. However the success rates of native tissue repair techniques for anterior vaginal prolapse range from %30-%70.
- Trial name
- NCT05444023
- Testing
- Pubocervical fascia reconstruction
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Stress Urinary Incontinence
Correction of Asymptomatic 2nd Degree Cystocele in Patient With Stress Incontinence
The aim of our study is to assess the value of concomitant surgical correction of asymptomatic grade II anterior vaginal wall prolapse with the placement of midurethral sling for treatment of female patients with stress…
- Trial name
- NCT03296748
- Testing
- trans-obturator tape inside-out usingsoft tapes., anterior colporraphy
- Where
- Egypt
- Volunteers
- 123 people
- Sponsor
- Kasr El Aini Hospital
Long Term Follow-Up, Transvaginal Cystocele Repair
Long Term Follow Up Of Transvaginal Cystocele Repair Using Four Armed Collagen Coated Polyester Mesh
This study aims to assess safety and efficacy of transvaginal repair of cystocele using four armed collagen coated polyester mesh beyond 5 years postoperatively.
- Conditions
- Long Term Follow-Up, Transvaginal Cystocele Repair, Four Armed Collagen, Polyester Mesh
- Trial name
- NCT07730749
- Testing
- transvaginal cystocele repair
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University