Clinical trials: Cystocele
Pelvic Organ Prolapse, Cystocele
Native Tissue Repair in Pelvic Organ Prolapse -Long-term Results and Risk of Re-operation
This study evaluates the recurrence of pelvic organ prolapse and the rate of re-operation after primary surgery for anterior vaginal wall prolapse with native tissue repair in long term follow-up.
- Trial name
- NCT06744972
- Volunteers
- 392 people
- Sponsor
- Turku University Hospital
Voiding Dysfunction
Randomized Controlled Trial of Cystocele Plication Risks ("CPR Trial"): A Pilot Study
Up to 50% of patients undergoing pelvic floor repair experience short-term postoperative voiding dysfunction, increasing the length of hospitalization, cost and anxiety among patients.
- Trial name
- CPR (NCT01197248)
- Testing
- Cystocele plication, No Plication
- Volunteers
- 40 people
- Sponsor
- Mount Sinai Hospital, Canada
Cystocele, Uterine Prolapse
Anterior Pelvic Prolapse Reconstruction With TiLOOP® PRO A Polypropylene Mesh
The purpose of this study is to determine the influence of anterior pelvic prolapse reconstruction with a titanized polypropylene mesh on patients quality of life.
- Trial name
- NCT02690220
- Testing
- TiLOOP® PRO Plus A
- Where
- 5 sites in Germany
- Volunteers
- 54 people
- Sponsor
- pfm medical gmbh
Cystocele
Transobturator Approach for Paravaginal Repair
A new technique for Applying sutures to the white line in paravaginal repair.
- Trial name
- NCT02735772
- Testing
- transobturator approach for paravaginal repair
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Pelvic Organ Prolapse (POP), Cystocele
Poly-L-Lactic Acid for Vulvovaginal Tissue Regeneration
Pelvic organ prolapse (POP) is a condition characterized by descent of vaginal walls, uterus and cervix, or the perineum and causes a sensation of vaginal bulge and pelvic pressure.
- Conditions
- Pelvic Organ Prolapse (POP), Cystocele, Pelvic Floor Disorder
- Trial name
- NCT07544667
- Testing
- Poly-L-Lactic Acid (Sculptra) injection
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cassandra Kisby
Urodynamic Stress Incontinence in Severe Cystocele Women
Evident, Occult and no Demonstrated USI and UDS Findings in Women With ≥Stage II Cystocele
Prevalence rates of urodynamic urinary incontinence (USI) subtypes and their related clinical and urodynamic findings in women with ≥ pelvic organ prolapse quantification stage II cystocele are important for clinical…
- Trial name
- NCT03613311
- Testing
- Urodynamic study
- Volunteers
- 480 people
- Sponsor
- National Taiwan University Hospital
Vaginal Prolapse
Avaulta Versus Anterior Repair
Summary: Vaginal prolapse is a well-known disease and is observed in approximately 11% of all postmenopausal women and tending to increase with age.
- Trial name
- NCT00627549
- Testing
- Avaulta (surgical procedure using a mesh implant), Conventional surgery (anterior repair)
- Where
- Denmark
- Sponsor
- Zealand University Hospital
Cystocele, Cystocele, Midline
Continuous Stitches Versus Simple Interrupted Stitches for Anterior Colporrhaphy
The anterior vaginal wall is the segment most commonly affected by prolapse. Traditionally, anterior vaginal wall prolapse is repaired via anterior colporrhaphy (native tissue repair), which is known to have a high recurrence…
- Conditions
- Cystocele, Cystocele, Midline, Vaginal Prolapse, Prolaps Bladder
- Trial name
- NCT05449054
- Testing
- Anterior colporrhaphy
- Where
- Austria
- Volunteers
- 48 people
- Sponsor
- Medical University of Vienna
Pelvic Organ Prolapse, Surgical Mesh
Clinical Outcomes of Transvaginal Mesh Procedures for Cystocele Repair: Comparisons of Uphold and Perigee Systems
Pelvic organ prolapse (POP) is a major health concern, affecting more than 30% of women. The aim of this study was to compare the clinical outcomes of Uphold system and Perigee system in treating women with cystocele.
- Trial name
- NCT03764891
- Testing
- Uphold, Perigee
- Where
- Taiwan
- Volunteers
- 152 people
- Sponsor
- Far Eastern Memorial Hospital
Cystocele
Nerve Access Tool Study
The purpose of this study is to assess the ability of the nerve access tool to facilitate nerve stimulation lead placement.
- Trial name
- NCT00942474
- Testing
- Facilitate nerve stimulation lead placement with the nerve access tool
- Sponsor
- MedtronicNeuro
Hernia, Cystocele
Surgical Treatment To Greater Anterior Vaginal Prolapse
A RCT study to compare traditional colporrhaphy versus polypropylene mesh in treatment of the anterior vaginal wall prolapse.
- Trial name
- Nazcatc™ (NCT00676325)
- Testing
- Surgical treatment of Anterior Vaginal Prolapse, NAZCA TC™ POP REPAIR SYSTEM ,promedon® , argentina., surgical treatment for anterior vaginal wall prolapse
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Vaginal Prolapse
Observational Data Collection of Surgical Outcomes in the Treatment of Vaginal Prolapse With AMS Products
This registry was observational (only collected information typically noted by the surgeon when their patients were routinely seen); there was no change to the care the patient received as a result of being part of the registry).
- Trial name
- POWER1012 (NCT00388947)
- Testing
- AMS Prolapse Product
- Where
- United States
- Volunteers
- 1,543 people
- Sponsor
- ASTORA Women's Health
Pelvic Organ Prolapse, Cystocele
Effectiveness Prolift+M Versus Conventional Vaginal Prolapse Surgery
Pelvic organ prolapse is highly prevalent in the female population. The recurrence rate of pelvic organ prolapse after surgical treatment is high.
- Conditions
- Pelvic Organ Prolapse, Cystocele, Rectocele, Uterine Prolapse
- Trial name
- VROUW2 (NCT02231099)
- Testing
- Prolift + M, conventional vaginal prolapse surgery
- Where
- 5 sites in Netherlands
- Volunteers
- 176 people
- Sponsor
- Radboud University Medical Center
Pelvic Organ Prolapse, Cystocele
A Randomized Controlled Trial of Permanent vs Absorbable Suture for Uterosacral Ligament Suspension
Uterosacral ligament suspension (USLS) is a commonly performed, vaginal surgery for the correction of female pelvic organ prolapse. The original description of this procedure included the use of permanent sutures.
- Conditions
- Pelvic Organ Prolapse, Cystocele, Uterine Prolapse
- Trial name
- NCT02888093
- Testing
- Absorbent suture (polydioxanone) and Permanent suture (Gore-Tex CV2)
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Joseph Kowalski
Vaginal Vault Prolapse, Enterocele
Sacrocolpopexy Versus Vaginal Mesh Procedure for Pelvic Prolapse
Pelvic prolapse is one of the most frequent pathology in Gynecology. Recurrency of the prolapse after primary surgery is relatively high, 15-30%.
- Conditions
- Vaginal Vault Prolapse, Enterocele, Uterine Prolapse, Cystocele
- Trial name
- NCT01097200
- Testing
- Elevate mesh, Sacrocolpopexy
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Francisco Carmona
Uterine Prolapse, Cystocele
Prophylactic Antibiotic Treatment During Vaginal Repair
Prolapse of the uterus, bladder and rectum is a common condition in multiparous and/or elderly women. The number of operations for vaginal repair is increasing in Denmark, but there is no consensus or evidence found about the…
- Conditions
- Uterine Prolapse, Cystocele, Rectocele, Enterocele
- Trial name
- NCT00162604
- Testing
- Cefuroxime
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Hvidovre University Hospital
Cystocele, Uterine Prolapse
Anterior Pelvic Prolapse Reconstruction With TiLOOP® Total 6
The purpose of this study is to determine the influence of Anterior Pelvic Prolapse Reconstruction with a titanised polypropylene mesh on rate of erosion and patients quality of live.
- Trial name
- NCT01084889
- Testing
- surgical mesh implantation (TiLOOP® Total 6)
- Where
- 9 sites in Germany
- Volunteers
- 292 people
- Sponsor
- pfm medical gmbh
Pelvic Organ Prolapse
Veritas Collagen Matrix Cystocele Repair Study - Postmarketing
The purpose of this study is to evaluate the Veritas Collagen Matrix in treating female patients with documented occurence of Pelvic Organ Prolapse as evidenced by a cystocele.
- Trial name
- NCT00860912
- Testing
- Collagen Matrix
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic