Clinical trials: Cystoid Macular Edema
Retinal Degenerations
Treatment of Cystoid Macular Edema in Patients With Retinal Degeneration
A small percentage of patients with retinal degeneration accumulate fluid in the center of their retina. Previous studies using an oral form of treatment has been successful in decreasing this fluid which improves vision.
- Trial name
- NCT00716586
- Testing
- 2% dorzolamide
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Illinois at Chicago
Resistant Cystoid Macular Edema
To Compare Therapeutic Effect of Intravitreal Bevacizumab and Triamcinolone in Resistant Uveitic Cystoid Macular Edema
Cystoid macular edema (CME) is one of the common causes of vision loss in patients with UveitiS .Triamcinolone has been effectively used in reducing CME and improving the vision.
- Trial name
- NCT00371111
- Testing
- Intravitreal injection of Triamcinolone, Intravitreal injection of Avastin
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Cystoid Macular Edema
Cystoid Macular Edema After Vitrectomy for Rhegmatogenous Retinal Detachment
To investigate the incidence of cystoid macular edema in eyes with primary rhegmatogenous retinal detachment successfully treated with vitrectomy with gas tamponade, and to evaluate the clinical variables associated with its…
- Trial name
- NCT05069675
- Testing
- vitrectomy
- Where
- 6 sites in Italy
- Volunteers
- 2,000 people
- Sponsor
- University of Catania
Age Related Cataracts, Cystoid Macular Edema
Evaluation of Central Macular Thickness in Femtosecond Laser-assisted Cataract Surgery
The investigational device is an approved femtosecond laser (FSL) device with an integrated imaging system to perform certain steps of the cataract procedure.
- Trial name
- FLAME (NCT03465124)
- Testing
- Femtosecond Laser, Manual Cataract Surgery
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Cystoid Macular Edema, Cataract
Anti-inflammatory Efficacy for Prophylaxis of Cystoid Macular Edema (CME) After Phacoemulsification
To compare the anti-inflammatory efficacy of ketorolac of tromethamine 0.4% and nepafenac 0.1% eye drops for prophylaxis of cystoid macular edema (CME) after small-incision cataract extraction.
- Trial name
- NCT02084576
- Testing
- Nepafenac, Ketorolac
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital Oftalmologico de Brasilia
Minocycline, Cystoid Macular Edema
Minocycline Treatment for Cystoid Macular Edema
Cystoid macular edema (CME) is one of sight-threatening, immune-related ocular diseases. The efficacy of current treatments for CME (anti-VEGF, glucocorticoids and other agents) are limiting.
- Trial name
- MINOCME (NCT05474950)
- Testing
- minocycline
- Where
- China
- Volunteers
- 5 people
- Sponsor
- Sun Yat-sen University
Diabetic Macular Edema, Cystoid Macular Edema, Chorodial Neovascularzation, Posterior Uveitis
Suprachoroidal Injection of Triamcinolone Acetonide Using Custom Made Needle to Treat Retinal Disorders
Injection in the Suprachoroidal space has potential of increasing the efficacy of the drug upto six times with direct effect on retinal tissues sparing the crystalline lens and trabecular meshwork.
- Trial name
- NCT03606733
- Testing
- Custom suorachoroidal needle
- Where
- Syria
- Volunteers
- 100 people
- Sponsor
- Marashi Eye Clinic
Uveitis Related Cystoid Macular Edema, Cystoid Macular Edema, Postoperative
Multicenter Study on the Efficacy and Safety of OCS-01 in Subjects With Uveitis Related and Post Surgical Macular Edema
The goal of the LEOPARD clinical trial is to investigate a new kind of steroid eye drops, OCS-01. Macular edema is a condition in which there is collection of fluid (edema) in the back of the eye (Macula) and it can lead to…
- Trial name
- LEOPARD (NCT05608837)
- Testing
- OCS-01
- Where
- 8 sites in United States
- Volunteers
- 28 people
- Sponsor
- Quan Dong Nguyen
Macular Edema, Cystoid Macular Edema
Dexamethasone Intravitreal Implant for Treatment of Macular Edema After Plaque Radiotherapy of Uveal Melanoma
To evaluate the safety and efficacy of dexamethasone intravitreal implant (Ozurdex) and compare it with safety and efficacy of intravitreal bevacizumab in eyes with macular edema after plaque radiotherapy of uveal melanoma.
- Conditions
- Macular Edema, Cystoid Macular Edema, Uveal Melanoma, Radiation Maculopathy
- Trial name
- NCT01471054
- Testing
- Ozurdex, Bevacizumab
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Arman Mashayekhi
Non-Proliferative Diabetic Retinopathy
Intravitreal and Intracameral DEX in NPDR
To investigate the effects of intravitreal and intracameral injection of dexamethasone during cataract phacoemulsification in patients with mild to moderate non-proliferative diabetic retinopathy
- Trial name
- NCT06951087
- Testing
- Dexamethasone sodium phosphate
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Affiliated Hospital of Nantong University
Uveitis, Cystoid Macular Edema
Pegaptanib Therapy in Non-Infectious Uveitic Cystoid Macular Edema
According to a recent estimate more than 280,000 people in the United States are affected by uveitis each year. This report, also estimated that uveitis is the reason for 30,000 new cases of blindness/year and up to 10 percent of…
- Trial name
- NCT00790803
- Testing
- Pegaptanib
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Wake Forest University
Uveitis, Cystoid Macular Edema
The Comparison Between the Therapeutic Affect of Intravitreal Diclophenac and Triamcinolone in Persistent Uveitic Cystoids Macular Edema
Cystoids macular edema (CME) is one of the most common causes of low vision due to uveitis. The treatment for reducing the intra-ocular inflammation can decrease the macular edema.
- Trial name
- NCT00893854
- Testing
- Diclophenac, Triamcinolone
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Cystoid Macular Edema, Fuchs Dystrophy
Descemet Membrane Endothelial Keratoplasty vs. Descemet's Stripping With Endothelial Keratoplasty vs. Descemet Stripping Only
This study aims to evaluate and compare incidence of post-operative cystoid macular edema (CME) after Descemet Membrane Endothelial Keratoplasty (DMEK), Descemet's Stripping Automated endothelial Keratoplasty (DSEK) and Descemet…
- Trial name
- NCT04527523
- Testing
- Optical Coherence Tomography
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Wake Forest University Health Sciences
Macular Edema, Cystoid
Effect of Prophylactic Ketorolac on CME After Cataract Surgery
The study will evaluate the efficacy of prophylactic administration of the topical nonsteroidal anti-inflammatory drug (NSAID) ketorolac tromethamine 0.5% (Acular®) on cystoid macular edema (CME) in patients having undergone…
- Trial name
- NCT00335439
- Testing
- ketorolac tromethamine 0.5% (Acular®)
- Where
- Canada
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Queen's University
Macular Oedema, Retinitis Pigmentosa
Aflibercept for Macular Oedema With Underlying Retinitis Pigmentosa (AMOUR) Study
The purpose of this study is to assess the safety and efficacy of intravitreal injections of Aflibercept (Eylea) in treating Cystoid Macula Oedema (CMO) in patients with underlying Retinitis Pigmentosa (RP).
- Trial name
- AMOUR (NCT02661711)
- Testing
- Aflibercept
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Retinitis Pigmentosa, Cystoid Macular Edema
Management of Cystoid Macular Edema Secondary to Retinitis Pigmentosa Via Subliminal Micropulse Yellow Laser
Purpose: To investigate the effects of subliminal micropulse yellow laser application on central macular thickness and best corrected visual acuity in cystoid macular edema secondary to retinitis pigmentosa patients.
- Trial name
- SL-MPL (NCT04234438)
- Testing
- SL-MPL treatment protocol was performed with a 577 nm yellow laser (EasyRet, Quantel Medical, Cedex, France)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Ankara Universitesi Teknokent
Cystoid Macular Edema,, Retinal Thickening
Bromfenac BID Plus Prednisolone Acetate BID Versus Bromfenac BID Plus Prednisolone QID for the Prevention of Cystoid Macular Edema and Retinal Thickening
The objective of this study is to determine if twice-daily dosing of prednisolone (Pred Forte) is as effective as four-times-daily dosing of prednisolone for the prevention of retinal thickening and cystoid macular edema (CME)…
- Trial name
- NCT00469781
- Testing
- 2. Xibrom (Bromfenac), 1. Pred Forte
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Center For Excellence In Eye Care
Retinitis Pigmentosa
Study of Oral Minocycline in Treating Bilateral Cystoid Macular Edema Associated With Retinitis Pigmentosa
Background: Some people with retinitis pigmentosa (RP) have macular edema (swelling) in the central retina. This can cause decreased central vision. The cause of macular edema is unknown, but may involve inflammation.
- Trial name
- NCT02140164
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- National Eye Institute (NEI)
Cystoid Macular Edema After Phacoemulsification
Prophylactic Effect of Ketorolac Tromethamine on the Cystoid Macular Edema After Phacoemulsification in Diabetic Patients
The aim of the study is determining the prophylactic effect of ketorolac tromethamine drop 0.5% eye drop on the functional and anatomical ocular characteristics of the diabetic patients after the phacoemulsification surgery.
- Trial name
- NCT03551808
- Testing
- using of Ketorolac Tromethamine Eye Drop
- Where
- Iran
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Epiretinal Membrane, Pseudophakic Cystoid Macular Edema
"Cataract Surgery in Eyes With Epiretinal Membrane"
The purpose of the study is to evaluate retinal thickness change and the occurrence of central structural retinal changes after uneventful small-incision cataract surgery in eyes with asymptomatic early stages of epiretinal…
- Conditions
- Epiretinal Membrane, Pseudophakic Cystoid Macular Edema, Irvine-Gass Syndrome, Cataract
- Trial name
- NCT03404323
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- St John of God Hospital, Vienna