Clinical trials: DEGLUTİTİON
Deglutition Disorder
Effect of Pre-emptive Transcutaneous Neuro-muscular Electrical Stimulation for Dysphagia in Long Term Intubated Patients
It was well known that long term intubation caused a various kind of abnormal presentations of dysphagia such as the increased aspiration risk, the decreased gag reflex, mucosal pathology, the airway stenosis and so on.
- Trial name
- NCT01202968
- Testing
- Transcutaneous neuro-muscular electrical stimulation
- Where
- South Korea
- Sponsor
- Ulsan University Hospital
Achalasia
Peroral Endoscopic Myotomy (POEM) for the Treatment of Achalasia
Achalasia is a chronic disease of altered esophageal motility with resulting functional obstruction to the passage of food leading to poor quality of life and significant morbidity.
- Trial name
- POEM (NCT01832779)
- Testing
- Achalasia subjects
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- University of Florida
Dyspepsia, Peptic Ulcer Disease
Minimally Invasive Evaluation of Dyspepsia by Combined Magnetically Controlled Capsule Endoscopy and Urea Breath Test: a Pilot Prospective Cohort Study
The combined diagnostic accuracy of MCCE and UBT in Hong Kong patients with uninvestigated dyspepsia between age 35 to 60 years for structural pathology and HP infection is comparable to that of conventional UGI endoscopy with…
- Conditions
- Dyspepsia, Peptic Ulcer Disease, Gastroesophageal Reflux, Ugi Malignancies
- Trial name
- MCUDYSPEPSIA (NCT04918472)
- Testing
- MCCE
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Thyroidectomy
Dysfunction Following Thyroid Surgery
Voice plays a crucial role in human communication and function. Voice production is multidimensional, involving physiologic, biomechanical, and aerodynamic mechanisms that produce an acoustic output that is perceived by the…
- Trial name
- NCT04087447
- Testing
- Thyroidectomy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Tracheostomy
Speaking Valve Influence on Breathing, Swallowing and Vocal Functions in Patients With Tracheostomy.
Speaking valve seems to have a beneficial influence on breathing and secretion management in certain patients with tracheostomy.
- Trial name
- NCT05482022
- Testing
- Shiley™ phonate speaking valve, control
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Loewenstein Hospital
Down Syndrome
Effects of Orofacial Therapy and Therapeutic Yoga in Children With Down Syndrome
The study aims to compare the effects of orofacial therapy and therapeutic yoga on swallowing, sleep habits, and quality of life in children with Down syndrome.
- Trial name
- NCT06352151
- Testing
- Routine Physiotherapy Group, Orofacial Treatment Group, Therapeutic Yoga Group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hasan Kalyoncu University
Dysphagia
Impact of Probiotics on Oral Microbiota in Older Adults With Dysphagia
The overall purpose of this study is to characterize the effect of probiotics on the oral microbiota in older adults with dysphagia at risk for pneumonia.
- Trial name
- NCT03682094
- Testing
- VSL#3
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Wisconsin, Madison
Dysphagia
Evaluation of Two Different Thickening Products in Patients With Dysphagia
Dysphagia is extremely common. The importance of providing adequate nutritional support to persons with dysphagia is the cornerstone to exceptional care.
- Trial name
- NCT01651975
- Testing
- Thickenup, Thickenup Advance
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Davis
Gastroesophageal Reflux
Gastroesophageal Reflux During LMA in Control Ventilation (LMA, Laryngeal Mask Airway)
Laryngeal mask airway is seldom used for control ventilation in America, while it is popular in China. The question is whether the incidence of gastroesophageal reflux in control ventilation is really higher than in spontaneous…
- Trial name
- LMA (NCT02441257)
- Testing
- control ventilation, spontaneous ventilation
- Volunteers
- 200 people
- Sponsor
- Zhenmeng Wang
Proximal Gastric Adenocarcinoma, Gastric Cancer
Proximal Gastrectomy Anterior Anastomosis With Pyloroplasty Versus Esophagogastric Anastomosis for Gastric Cancer
This research is designed to compare proximal gastrectomy anterior anastomosis with pyloroplasty with esophagogastric anastomosis for gastric cancer.
- Conditions
- Proximal Gastric Adenocarcinoma, Gastric Cancer, Gastroesophageal Reflux Disease
- Trial name
- NCT05514769
- Testing
- Proximal Gastrectomy Anterior Anastomosis With Pyloroplasty
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Nanchong Central Hospital
Sore Throat, Dysphagia
LMA Cuff Pressure and LMA-induced Complications
The purpose of this study is to determine if using 20 mL B.Braun syringes to inflate LMAs and allowing them to recoil will put the pressure of the LMA cuff within the safety range.
- Conditions
- Sore Throat, Dysphagia, Dysphonia
- Trial name
- NCT01385969
- Testing
- Standard inflation of LMA cuff, Pressure check with syringe recoil, Pressure check by pressure transducer
- Where
- 2 sites in United States
- Volunteers
- 360 people
- Sponsor
- Mayo Clinic
Head and Neck Cancer
Effects of Swallowing Therapy in Head and Neck Cancer
Treatment for head and neck cancer often results in significant swallowing problems because of reduced range of motion (ROM) of the larynx, tongue base, and pharyngeal walls.
- Trial name
- NCT00214305
- Testing
- Range of Motion Therapy Program, Postural Sensory Therapy Program
- Where
- United States
- Sponsor
- University of Wisconsin, Madison
Gastroesophageal Reflux
Targeting Hypervigilance and Autonomic Arousal: the Psycho-physiologic Model of Gastroesophageal Reflux Disease (GERD)
GERD affects roughly 20% of the U.S. population and the direct and indirect costs of GERD are substantial, totaling close to 50 billion dollars per year.
- Trial name
- NCT04960566
- Testing
- Cognitive Behavioral Therapy
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Northwestern University
Dysphagia
Outpatient Swallowing Therapy for Subjects With Neurological Illness
Health care staff in the municipalities do not always have the necessary competencies to treat patients with dysphagia. At the present neurorehabilitation hospital dysphagia examinations for outpatients are provided.
- Trial name
- NCT04595643
- Testing
- Combination of different dysphagia training modalities
- Where
- Denmark
- Volunteers
- 5 people
- Sponsor
- University of Aarhus
Ischaemic Stroke, Hemorrhagic Stroke
Exploratory Study on the Potential Cross-System Effects of BCI-FES Hand Therapy on Dysphagia and Aphasia in Chronic Stroke Patients
The goal of this neurorehabilitation explorative study is to investigate how a closed-loop Brain-Computer Interface Functional Electrical Stimulation (BCI-FES) therapy, used within the intended purpose for hand rehabilitation…
- Trial name
- c-STEPS (NCT06940635)
- Testing
- closed-loop BCI-FES device
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- VASCage GmbH
Amyotrophic Lateral Sclerosis, Dysphagia
Fatigue in Patients With Amyotrophic Lateral Sclerosis
Expiratory muscle strength training (EMST) is an emerging palliative intervention for prolonging pulmonary and swallow function in patients with amyotrophic lateral sclerosis (PALS), but it is unknown whether EMST may result in…
- Conditions
- Amyotrophic Lateral Sclerosis, Dysphagia, Dyspnea, Respiration Disorders
- Trial name
- NCT04468191
- Testing
- Experimental expiratory muscle strength training (EMST)
- Where
- United States
- Sponsor
- Cara Donohue
Achalasia
Per-Oral Endoscopic Esophagomyotomy (POEM)
Achalasia is an esophageal motility disease that usually requires surgical intervention (esophagomyotomy). Laparoscopic techniques have reduced the morbidity associated with myotomy, but post-op GERD, wound infection, hernia and…
- Trial name
- POEM (NCT01635374)
- Testing
- Per-Oral Endoscopic Esophagomyotomy
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Northwestern University
Thymidine Kinase 2 (TK2)
A RETROspective Study of Patients With TK2d
This is a medical chart review study to collect information for patients who have been taking pyrimidine nucleosides for treatment of TK2 deficiency.
- Trial name
- RETRO (NCT03701568)
- Testing
- dC/dT
- Where
- 8 sites in United States, Israel and 1 more
- Volunteers
- 38 people
- Sponsor
- Zogenix MDS, Inc.
Gastroesophageal Reflux, Sleep Apnea
Evaluation of Gastroesophageal Reflux in Patients on Continuous Positive Airway Pressure Ventilation for Obstructive Sleep Apnea
Patients with a clinically indicated sleep study will be enrolled in this study. They will have a diagnostic and a therapeutic sleep study with continuous positive airway pressure ventilation.
- Trial name
- NCT00194376
- Testing
- Continuous positive airway pressure ventilation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Pennsylvania
Gastroesophageal Reflux Disease
Compound Sodium Alginate Double Action Chewable Tablets 4-hour Esophageal pH Study in GERD Patients
This study is being conducted to assess the effectiveness of the Compound Sodium Alginate Double Action Chewable Tablets compared to placebo on acidic reflux events into the esophagus in patients diagnosed with Gastroesophageal…
- Trial name
- NCT01872897
- Testing
- Sodium Alginate Double Action Chewable Tablets
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
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