Clinical trials: DEGLUTİTİON
Gastroesophageal Reflux Disease
Survey to Describe Impact of Reflux Disease on Everyday Life in GERD Patients Before and After 4 Weeks Treatment.
To describe the change of impact of reflux symptoms on the everyday life perceived by patients before and after 4 weeks treatment by using GERD Impact Scale questionnaire (GIS) by total GERD patient population and by treatment…
- Trial name
- NCT00786773
- Where
- 18 sites in Vietnam
- Volunteers
- 2,091 people
- Sponsor
- AstraZeneca
Dysphagia
Effect of Acupuncture Therapy on Dysphagic Parkinson's Patients
We are currently conducting a randomized controlled study in China, specifically in three hospitals' rehabilitation medicine departments, focusing on dysphagic participants with Parkinson's disease.
- Trial name
- NCT06255756
- Testing
- Routine rehabilitation training, Swallowing rehabilitation training, Acupuncture therapy
- Where
- China
- Sponsor
- Zeng Changhao
Autism, Gastrointestinal Symptoms
A Study to Assess the Role of a Gluten Free-dairy Free (GFCF) Diet in the Dietary Management of Autism Associated Gastrointestinal Disorders
Doctors at MassGeneral Hospital for Children (MGHfC) are doing a research study to learn if a gluten free-dairy free (GFCF) diet is helpful in improving gastrointestinal symptoms associated with autism.
- Trial name
- GFCF (NCT01116388)
- Testing
- GFCF product with GFCF diet, product containing gluten and casein (milk protein) with GFCF diet
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- Massachusetts General Hospital
Caregiver Burden, Alzheimer's Disease
WeCareToFeedDysphagia to Reduce Care-partner Burden Full-scale RCT
The goal of this clinical trial is to learn if a newly-created website tool, called WeCareToFeedDysphagia, helps to reduce feelings of burden in care partners of patients with Alzheimer's disease and related dementias (AD/ADRD)…
- Conditions
- Caregiver Burden, Alzheimer's Disease, Dementia, Oropharyngeal Dysphagia
- Trial name
- NCT07250113
- Testing
- WeCareToFeedDysphagia web tool
- Where
- United States
- Volunteers
- 802 people
- Sponsor
- Northwell Health
Gastroesophageal Reflux
Study to Evaluate the Pharmacokinetics and Safety of Dexlansoprazole in Pediatric Subjects With Symptomatic Gastroesophageal Reflux Disease
The purpose of this study is to assess the pharmacokinetics and safety of dexlansoprazole, once daily (QD), in pediatric subjects with symptomatic Gastroesophageal Reflux Disease.
- Trial name
- NCT01045096
- Testing
- Dexlansoprazole
- Where
- 4 sites in United States
- Volunteers
- 36 people
- Sponsor
- Takeda
Gastroesophageal Reflux Disease
Treatment of Gastroesophageal Reflux Disease in 12-16 Year Old Patients With Rabeprazole
The primary objective of this study is to collect safety information on rabeprazole 10 mg and 20 mg in the treatment of gastroesophageal reflux disease (GERD) in children aged 12 to 16 years.
- Trial name
- NCT00132496
- Testing
- rabeprazole sodium
- Where
- 25 sites in United States
- Volunteers
- 111 people
- Sponsor
- Eisai Inc.
Esophageal Achalasia, Esophageal Motility Disorders
Different Surgical Procedures of Peroral Endoscopic Myotomy(POEM) for Esophageal Achalasia
This study compares the clinical efficacy of safety of circular myotomy and full-thickness myotomy guided by peroral endoscopic in treatment of incision length of ≤7cm and of ≥7cm in achalasia patients.
- Trial name
- NCT03012854
- Testing
- short-myotomy, long-myotomy, full-thickness myotomy
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Dysphagia
Nutrition-dense Smoothie Diets Reduced Dysphagia Risk in the Elderly
The investigators aimed to compare the effect of consuming high protein (23-34% energy ratio) and low carbohydrate (25-38% energy ratio) smoothie formulas vs.
- Trial name
- NCT04901182
- Testing
- the effect of consuming diets on the swallowing capacity by using Flexible Endoscopic Evaluation of Swallowing (FEES)
- Where
- Thailand
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Gastroesophageal Reflux
Effect of Vecam 40/300 and Vecam 20/300 Compared to Omeprazole 20 mg on Gastric pH
The study is designed to assess and compare the effect of Vecam 40/300, Vecam 20/300 and Omeprazole 20 mg (a standard FDA approved GERD treatment) on the control of gastric pH.
- Trial name
- NCT00818870
- Testing
- Omeprazole, Vecam
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vecta Ltd.
Deglutition Disorders, Otorhinolaryngologic Diseases
A Predictive Model for Oropharyngeal Dysphagia in Non-hospitalized Older Patients
Oropharyngeal dysphagia (OD) is a highly prevalent and growing condition in the older population. It affects approximately one in three community-dwelling elderly, almost half of the geriatric patients, and even more than half of…
- Conditions
- Deglutition Disorders, Otorhinolaryngologic Diseases, Oropharyngeal Dysphagia
- Trial name
- NCT05862142
- Testing
- No intervention
- Volunteers
- 300 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Non-erosive Reflux Disease
Comparing Omeprazole With Fluoxetine for Treatment of Non Erosive Reflux Disease and Its Subgroups: a Double-blind Placebo-controlled Clinical Trial
Gastro-esophageal reflux disease (GERD) is highly prevalent, affecting up to 20% of the adult population in North America. Up to 70% of GERD patients have non-erosive reflux disease (NERD), a term used to describe symptoms…
- Trial name
- NCT01269788
- Testing
- Fluoxetine, Omeprazole
- Where
- Iran
- Volunteers
- 144 people
- Sponsor
- Tehran University of Medical Sciences
Irritable Bowel Syndrome, Gastro-oesophageal Reflux Disease
The Influence of Concomitant Irritable Bowel Syndrome on Gastro-Oesophageal Reflux Disease Symptoms and Severity.
This research aims to investigate whether there is a link between irritable bowel syndrome (IBS) and acid reflux, particularly whether there is a difference in acid reflux symptoms between people with and without IBS.
- Trial name
- NCT06615856
- Testing
- Questionnaire
- Volunteers
- 124 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Gastroesophageal Reflux Disease
Epi-GERD Study: Epidemiological Evaluation in Patients With Gastro-Esophageal Reflux Disease (GERD)
Cross-sectional epidemiological study in patients with diagnosis of GERD (Gastroesophageal Reflux Disease) and with current treatment or with a history of recent treatment with some PPI (Proton Pump Inhibitor), in order to…
- Trial name
- Epi-ERGE (NCT04094402)
- Testing
- None. It is an observational study
- Where
- Colombia
- Volunteers
- 1,500 people
- Sponsor
- Scandinavia Pharma
Gastroesophageal Reflux Disease
The Effect of PPI in Preventing Gastroesophageal Reflux Disease of Seafarers
In view of the high incidence of GERD among seafarers and its continuing impact on the life quality of seafarers, it is necessary to use preventive treatment.
- Trial name
- NCT04696783
- Testing
- Esomeprazole Magnesium Enteric-coated Tablets, Lifestyle adjustment
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Oral Dryness and Saliva Altered, Oral Manifestations
The Effects of Using Augmented Reality (AR) System to Train Foreign Care Workers.
The aim of this study was to evaluate the effect of augmented reality (AR) system training intervention of foreign care workers on the salivary biomarker and oral function of older people.
- Conditions
- Oral Dryness and Saliva Altered, Oral Manifestations, Swallowing Disorder
- Trial name
- NCT05938166
- Testing
- oral care augmented reality (AR), video-based oral hygiene education course
- Where
- Taiwan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Esophageal Cancer
Palliative Radiotherapy and Brachytherapy for Oesophageal Cancer Dysphagia
Hypothesis: In the management of advanced oesophageal cancer, to determine if a shorter regime of external beam radiotherapy (using higher daily doses, and combined with intraluminal high dose rate brachytherapy) is not inferior…
- Trial name
- NCT00665197
- Testing
- Protracted Course Radiotherapy, Short Course Radiotherapy
- Where
- 7 sites in Canada, China and 5 more
- Volunteers
- 200 people
- Sponsor
- International Atomic Energy Agency
Reflux, Gastroesophageal Reflux Disease (GERD)
RESULT (REflux Surgery in Lung Transplantation) Preliminary Study Protocol
The purpose of the prospective study is to collect information surrounding lung transplant in order to develop a randomized study to determine if prevention of gastroesophageal reflux disease (GERD) related aspiration (stomach…
- Trial name
- RESULT (NCT01406210)
- Where
- 4 sites in United States, Canada
- Volunteers
- 647 people
- Sponsor
- Duke University
Infantile Colic, Gastroesophageal Reflux (GER)
BioAmicus Complete for Functional Gastrointestinal Symptoms in Infants Aged 0 to 24 Months
Infants often experience functional gastrointestinal symptoms (e.g., colic, excessive gas, regurgitation, constipation, or loose stools) that distress families and may reflect an imbalance of the gut microbiome.
- Conditions
- Infantile Colic, Gastroesophageal Reflux (GER), Functional Constipation, Functional Diarrhea
- Trial name
- CTBE2503 (NCT07148583)
- Testing
- BioAmicus Complete, Usual Care (No Probiotic)
- Where
- Vietnam
- Volunteers
- 110 people
- Sponsor
- Haiphong University of Medicine and Pharmacy
Gastroesophageal Reflux Disease (GERD)
A Study to Check the Safety of Dexlansoprazole and Learn if it Can Treat Symptomatic Nonerosive Gastroesophageal Reflux Disease in Children 2 to 11 Years Old
Gastroesophageal reflux disease (GERD) is caused by food or acid coming up from the stomach into the esophagus, repeatedly. The esophagus is the tube that carries food and liquids from the mouth to the stomach.
- Trial name
- NCT02616302
- Testing
- Dexlansoprazole
- Where
- 18 sites in United States, Canada and 3 more
- Volunteers
- 71 people
- Sponsor
- Takeda
Dysphagia
Effect of Oral Enteral Nutrition in Nasopharyngeal Carcinoma Survivors With Swallowing Disorders
This is a prospective multicenter study with patients with delayed dysphagia after radiotherapy. Patients enrolled are randomly divided equally into the observation group and the control group.
- Trial name
- NCT06301672
- Testing
- Nasogastric Tube Feeding, Intermittent Oral-esophageal Tube Feeding, comprehensive rehabilitation therapy
- Volunteers
- 60 people
- Sponsor
- Muhammad
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