Clinical trials: DEGLUTİTİON
GERD
Alginate vs Sucralfate for GERD Symptomatic Relief
Gastroesophageal reflux disease (GERD) is a chronic gastrointestinal disorder characterized by the regurgitation of gastric contents into the esophagus.It can also present in an atypical manner such as chest pain, dental…
- Trial name
- NCT07310927
- Testing
- Alginate, Sucralfate
- Where
- Pakistan
- Volunteers
- 140 people
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
Achalasia, GORD
vMII for Measurement of Oesophageal Bolus Transport and Reflux
Recent work at St. Thomas' has validated an innovative new design of a multichannel intraluminal impedance (MII) catheter that is sensitive to variation in oesophageal volume in healthy volunteers and patients.
- Trial name
- vMII (NCT00604942)
- Testing
- Heller's Myotomy, Nissen Fundoplication, domperidone or esomeprazole (Conservative management)
- Where
- United Kingdom
- Volunteers
- 140 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
GERD, Cardiac Event
Cardiac Safety of Lansoprazole and Domperidon Combination
The aim of current study is to compare safety and efficacy of lansoprazole/domperidone 30/30 mg sustained release capsules (brand name: Duolans) and lansoprazole 30 mg micropellet capsules (brand name: Lasotab) in GERD patients…
- Conditions
- GERD, Cardiac Event, Safety Issues
- Trial name
- NCT03355170
- Testing
- Lansoprazole/Domperidone, Lansoprazole
- Where
- 16 sites in Turkey (Türkiye)
- Sponsor
- Neutec Ar-Ge San ve Tic A.Ş
Bariatric Surgery, Morbid Obesity
Comparison of Three Hypoabsortive Surgical Techniques for Treatment of Type IV Morbid Obesity
Morbid obesity is the first non-traumatic cause of death in the western population and it is also progressively beginning to affect the developing countries.
- Trial name
- BAR-3 (NCT04861961)
- Testing
- DS vs. SADI-S vs. OAGBP
- Where
- Spain
- Volunteers
- 186 people
- Sponsor
- Hospital Universitari de Bellvitge
GERD
Physiology of GERD and Treatment Response
This study is designed to assess the physiologic and behavioral mechanisms associated with enhanced medication effects in adult patients with functional GERD-related symptoms.
- Trial name
- NCT04292470
- Testing
- Amitriptyline
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Respiratory Aspiration of Gastric Contents
Gastric Ultrasound for Estimation of the Aspiration Risk Study
The purpose of this research study is to look at the effectiveness of current anesthesia guidelines regarding food and drink prior to surgery in patients who are likely to have food and drink remain in their stomach longer than…
- Trial name
- NCT03310528
- Testing
- Interview questionnaire, Gastric ultrasound exam
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Florida
Achalasia, Gastroesophageal Reflux Disease
Prospective Collection of Outcome Data Post POEM-TIF Procedure
Per Oral Endoscopic Myotomy has been established as a safe and effective treatment of Achalasia type I and II; however, it is limited by post-procedure gastroesophageal reflux.
- Trial name
- NCT04052581
- Testing
- POEM-TIF
- Sponsor
- Johns Hopkins University
Cerebral Infarction, Sleep Apnea, Obstructive
High-flow Nasal Cannula Oxygen Therapy for Ischemic Stroke Patients With Dysphagia and Obstructive Sleep Apnea
High flow nasal cannula (HFNC) ventilation therapy was found to improve the severity of obstructive sleep apnea in non-stroke subjects.
- Conditions
- Cerebral Infarction, Sleep Apnea, Obstructive, Deglutition Disorders
- Trial name
- NCT04173767
- Testing
- high flow nasal cannula ventilation
- Where
- Taiwan
- Volunteers
- 22 people
- Sponsor
- Chang Gung Memorial Hospital
Dysphagia
Efficacy of Two Interventions Increasing Sensory Stimulus in Elderly Patients With Oropharyngeal Dysphagia
This study will evaluate with videofluoroscopy (radiologic method to study the deglutitive physiology) the effect on the deglutition of two therapeutic treatments with the duration of 2 weeks, based on the increase of the…
- Trial name
- NCT01762228
- Testing
- Transcutaneous electrical stimulation, TRPV1 agonist
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- Hospital de Mataró
Otorhinolaryngologic Disease, Otorhinolaryngologic Neoplasm
Ultrasound Evaluation of Tongue Movements in Speech and Swallowing
This study will assess the use of ultrasound-a test that uses sound waves to produce images-as a diagnostic tool for evaluating speech and swallowing.
- Conditions
- Otorhinolaryngologic Disease, Otorhinolaryngologic Neoplasm, Pharyngeal Neoplasm, Polymyositis
- Trial name
- NCT00001167
- Where
- United States
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Minimally Conscious State, Vegetative State
The Initiation of Swallowing Can Indicate the Prognosis of DOC
This study is aimed to detect the initiation of swallowing act in DOC patients, to find if it is a good item as a stimulus and to detect the relationship between the initiation of swallowing act and the prognosis of DOC patients.
- Trial name
- NCT03508336
- Testing
- Coma Recovery Scale-Revised
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Hangzhou Normal University
Gastroesophageal Reflux
The Use of Proton Pump Inhibitor for the Treatment of Non-erosive Gastro-oesophageal Reflux Disease in Chinese Population
The purpose of this study is to evaluate the efficacy of proton pump inhibitor for the treatment of non-erosive reflux disease (NERD) in Chinese population.
- Trial name
- NCT00516971
- Testing
- Esomeprazole 20mg once daily
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Hospital Authority, Hong Kong
Reflux, Gastroesophageal
Comparison of Total and Partial Fundoplication During Surgery of Patients With Gastroesophageal Reflux Disease
460 patients who are scheduled for surgical treatment of gastroesophageal reflux disease (GERD) participate in the study following the usual preoperative Clinical routines (Medical history, endoscopy with biopsies, esophageal…
- Trial name
- RefluxII (NCT03659487)
- Testing
- Nissen, Toupét
- Volunteers
- 460 people
- Sponsor
- Karolinska Institutet
Gastroesophageal Reflux
Esophageal Bolus Transit in Newborns With Gastroesophageal Reflux Disease
Esophageal dysmotility due to immaturity could promote impaired bolus transit during esophageal swallow events,thus influencing gastroesophageal reflux (GER) clearance.
- Trial name
- NCT02167984
- Where
- Italy
- Volunteers
- 61 people
- Sponsor
- University of Turin, Italy
Gastro-esophageal Reflux Disease (GERD)
Compound Sodium Alginate Oral Suspension Sachet 4-hour Esophageal pH Study in GERD Patients
Multi-centre, randomised, open-label, placebo-controlled, two-period crossover study of 4 hour pH monitoring following a refluxogenic meal and drink.
- Trial name
- NCT02619747
- Testing
- Compound Sodium Alginate Oral Suspension sachet
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Cardiovascular Diseases, Dysphagia
Clinical Markers of Dysphagia in Cardiac Surgical Patients
Although dysphagia is a known complication of cardiac surgery, risk factors and sensitive bedside clinical markers of dysphagia have not yet been identified.
- Trial name
- NCT05304416
- Testing
- Fiberoptic Endoscopic Evaluation of Swallowing, Simultaneous FEES and Videofluoroscopy instrumental swallowing exam, Videofluoroscopy instrumental swallowing exam (VFSS)
- Where
- 2 sites in United States
- Volunteers
- 347 people
- Sponsor
- University of Florida
Gastroesophageal Reflux Disease
Stellate Ganglion Block on Gastroesophageal Reflux Disease
The goal of this clinical trial is to explore Clinical Effect of Stellate Ganglion Block on Gastroesophageal Reflux Disease. The main question it aims to answer is: Can stellate ganglion block improve gastroesophageal reflux…
- Trial name
- NCT06319521
- Testing
- Rehabilitation therapy, Stellate ganglion block, Lidocaine hydrochloride
- Volunteers
- 80 people
- Sponsor
- Copka Sonpashan
GERD
Pre- and Post-Therapy Evaluation of Air-Associated Symptoms in Patients With Gastro-esophageal Reflux Disease (GERD): Assessing the Role of Speech and Language Therapy
Patients with gastroesophageal reflux disease (GERD) may present with concomitant gas-related symptom (GRS) such as supragastric or gastric belching, and aerophagia.
- Trial name
- LAS (NCT07634614)
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Prof Urs Zingg
Roux-en-y Anastomosis Site, Marginal Ulcer
Marginal Ulcer Healing With Low-Thermal Argon Plasma Endoscopic Treatment
The objective of the study is to investigate the treatment of marginal ulcers with Low Thermal plasma in an endoscopic setting. By a treatment of the ulcerated areas with argon plasma with low power settings (~ 1 W) we…
- Conditions
- Roux-en-y Anastomosis Site, Marginal Ulcer, Marginal Ulcer (Peptic) or Erosion, Ulcer
- Trial name
- AMULET (NCT06543316)
- Testing
- Low Thermal Plasma (LTP) Treatment, Standard of Care Ulcer Treatment (typically PPI Administration)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Christopher C. Thompson, MD, MSc
Deglutition Disorders, Stroke
Computerized Acoustic Swallowing Evaluation
It is the purpose of this study to determine if a commercially available electronic stethoscope synchronized with an smart phone or iPad application can be used as an accurate and objective screening tool for measuring dysphagia.
- Trial name
- CASE (NCT02925507)
- Testing
- Swallowing Screen
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
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