Clinical trials: DEGLUTİTİON
Gastroesophageal Reflux Disease, Chronic Laryngitis
Laryngeal and Esophageal EGF-r Expression in Patients With Reflux Laryngitis
Saliva plays an important role in the homeostasis of the digestive tract mucosa. Salivary organic components, such as the Epidermal Growth Factor(EGF) have been found in defficient concentrations in patients with gastroesophageal…
- Trial name
- EGFR (NCT01806220)
- Testing
- Biopsy of the retrocrycoid laryngeal mucosa, Biopsy of the distal esophageal mucosa
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Gastro Esophageal Reflux
Antireflux Mucosectomy (ARMS) for Treatment of Gastroesophageal Reflux
This is a phase II clinical study to investigate the safety and efficacy of endoscopic antireflux mucosectomy (ARMS) for treatment of GERD.
- Trial name
- ARMS (NCT04194723)
- Testing
- Antireflux Mucosectomy
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- Chinese University of Hong Kong
Laryngopharyngeal Reflux
Twice Daily Prevacid for the Treatment of Laryngopharyngeal Reflux
The purpose of this study is to determine whether treatment with twice-daily Lansoprazole 30mg (Prevacid 30mg) and behavioral modifications for reflux is superior to treatment with behavioral modifications for reflux alone in the…
- Trial name
- NCT00864396
- Testing
- Prevacid
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of California, Davis
Parkinson's Disease, Deglutition Disorders
Swallowing Training in Parkinson's Disease
Dysphagia in Parkinson's disease(PD) is common and its presence is related to motor and sensory abnormalities, and incoordination between swallowing and breathing.
- Conditions
- Parkinson's Disease, Deglutition Disorders, Voice Disorders
- Trial name
- NCT01131494
- Testing
- Motor exercises for swallowing, breathing and phonation
- Where
- Brazil
- Volunteers
- 17 people
- Sponsor
- Federal University of Bahia
Microaspiration, Gastro Esophageal Reflux
Transpyloric Feeding for Prevention of Micro-aspiration
To determine the effect of transpyloric (TP) feeding on microaspiration and lung inflammation in ventilated preterm infants.
- Trial name
- NCT03646045
- Testing
- Transpyloric feeding
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Nemours Children's Clinic
Head and Neck Neoplasms
Oropharyngeal Function After Radiotherapy With IMRT
This project defines the effect on swallowing of intensity modulation during radiotherapy in an organ preservation treatment involving chemoradiation for 125 oral, laryngeal, and pharyngeal cancer patients with previously…
- Trial name
- NCT00506324
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Northwestern University
Dysphagia
AI-Based Dysphagia Rehabilitation Program: Development and Validation
The goal of this clinical study is to learn if an artificial intelligence (AI)-assisted swallowing rehabilitation program can improve swallowing function in adults with dysphagia.
- Trial name
- NCT07767123
- Testing
- Neuromuscular electrical stimulation for swallowing, Multi-sensor swallowing screening for dysphagia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Research Center for Rehabilitation Technical Aids
Esophageal Diseases, Achalasia
PRospective Registry of Esophageal Motility
Digestive physiopathology is a branch of gastroenterology aiming to study patients with upper GI symptoms, mainly gastro-esophageal, potentially indicating the presence of Gastroesophageal Reflux Disease (GERD)/Barrett Esophagus…
- Conditions
- Esophageal Diseases, Achalasia, Eosinophilic Esophagitis, Motility Disorder
- Trial name
- PREM (NCT07506746)
- Testing
- No intervention
- Where
- Italy
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Preterm Birth, Tube Feeding
Maternal Role in Oral Feed Establishment in Preterm Neonates
Hypothesis Preterm babies who receive sensory motor stimulation from their mothers as compared to trained nurses will 1. Start taking oral feed at the same time as compared to control group 2.
- Conditions
- Preterm Birth, Tube Feeding, Swallowing Disorder, Maternal Care Patterns
- Trial name
- NCT05484726
- Testing
- perioral sensory motor stimulation
- Where
- Pakistan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Fatima Memorial Hospital
Laryngopharyngeal Reflux
Treatment of Extraesophageal Reflux With the Reza Band UES Assist Device
The purpose of the study is to determine the safety and effectiveness of non-invasive Reza Band UES Assist Device for the treatment of esophagopharyngeal reflux with extra-esophageal symptoms (chronic cough, choking, aspiration…
- Trial name
- NCT01857713
- Testing
- Reza Band UES Assist Device
- Where
- 5 sites in United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Somna Therapeutics, L.L.C.
Cardiovascular Disease
Prevention and Treatment of Cardiovascular Disease
In view of the close interrelationship between the various organs and systems of the body, which cannot be examined in a parceled fashion but rather as an integrated system, this study aims to consider the potential risks…
- Trial name
- VPC (NCT06413823)
- Where
- Italy
- Volunteers
- 218 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Dysphagia
Acupuncture Technique for Restoring Consciousness on Post-stroke Dysphagia
This is a randomized controlled study, including post-stroke dysphagic patients. The participants were divided randomly into the experimental group and the control group.
- Trial name
- NCT06328582
- Testing
- Routine rehabilitation training, Acupuncture Technique for Restoring Consciousness combined with Scalp Acupuncture
- Volunteers
- 60 people
- Sponsor
- Copka Sonpashan
Gastro Esophageal Reflux
The Effect of Positional Therapy on Symptoms of Gastroesophageal Reflux Disease: A Prospective Pilot Study
Gastroesophageal reflux disease related symptoms are reported by 10-20% of the adult population and of those 50-75% report symptoms during sleep time.
- Trial name
- NCT04500288
- Testing
- LEFT Device
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Dysphagia, Parkinson's Disease (PD)
rTMS Treatment of Dysphagia in Parkinson's Patients
The study was conducted with patients with dysphagia who were followed up with Parkinson's disease in the neurology and physical therapy rehabilitation departments.
- Trial name
- NCT07221110
- Testing
- Repetitive Transcranial Magnetic Stimulation, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Ege University
Mastication Disorder, Stroke
Oral Tactile Sensitivity in Stroke Patients
Orofacial impairment following stroke frequently involves a reduced chewing performance and dysphagia. This study investigated the sensitivity of oral tissues following stroke and its potential impact on chewing efficiency.
- Conditions
- Mastication Disorder, Stroke, No Problem Chewing, Dysphagia
- Trial name
- NCT02822391
- Testing
- observation
- Where
- Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Bern
Gastro Esophageal Reflux
Comparison of Esomeprazole Versus Vonoprazan in Gastroesophageal Reflux Disease
Local literature is deprived of data comparing the effectiveness of esomeprazole and vonoprazan in patients with gastroesophageal reflux disease (GERD).
- Trial name
- NCT07563491
- Testing
- Esomeprazole, Vonoprazan
- Where
- Pakistan
- Volunteers
- 824 people
- Sponsor
- Muhammad Aamir Latif
Erosive Esophagitis
Endoscopic Evidence of Maintenance of Healing With Oral NEXIUM in Patients 1 to 11 Years Old With Erosive Esophagitis.
The aim of the study is to compare the safety and efficacy of two doses of Nexium in maintaining healing of erosive esophagitis in patients 1 to 11 years of age.
- Trial name
- EE (NCT05267613)
- Testing
- Nexium 20mg, Nexium 10mg
- Where
- 41 sites in United States, Argentina and 8 more
- Volunteers
- 53 people
- Sponsor
- AstraZeneca
Esophageal Motility Disorders
Changes in Esophageal Motility and Swallowing Symptoms After Thyroid Surgery
The pronounced effect of goiter on the esophagus needs further exploration, as the mechanisms by which goiter leads to swallowing difficulties are unknown.
- Trial name
- NCT03100357
- Testing
- Thyroidectomy
- Volunteers
- 39 people
- Sponsor
- University of Southern Denmark
Barrett's Esophagus, GERD
Cytosponge Adequacy Study Evaluation II
This study will assess the Minimally Invasive Esophageal Cytology Collection System in Patients with Barrett's Esophagus or GERD Symptoms.
- Trial name
- CASEII (NCT02395471)
- Testing
- Cytosponge™ Cell Collection Device
- Where
- 5 sites in United States
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Oropharyngeal Dysphagia, Stroke
Treatment of Chronic Post-stroke Oropharyngeal Dysphagia With Paired Stimulation
According WHO, oropharyngeal dysphagia (OD) is a prevalent post-stroke (PS) condition involving the digestive system (ICD-10: I69.391) and an independent risk factor for malnutrition and pulmonary infection; and leads to greater…
- Conditions
- Oropharyngeal Dysphagia, Stroke, Stroke, Complication, Swallowing Disorder
- Trial name
- ICI20/00117 (NCT05720871)
- Testing
- rTMS + capsaicin 150μM (natural TRPV1 agonist), tDCS + capsaicin 150μM (natural TRPV1 agonist)
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Hospital de Mataró
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