Clinical trials: DIEP Flap Breast Reconstruction
Breast Neoplasms, Breast Reconstruction
DIEP-MDS for Risk Stratification of Flap Vascular Compromise and Failure in Breast Reconstruction
This multicenter retrospective observational study will develop and validate a CTA-based quantitative risk score-the DIEP Morphological Deviation Score (DIEP-MDS)-to estimate the risk of flap-related vascular compromise and flap…
- Conditions
- Breast Neoplasms, Breast Reconstruction, Postoperative Complications
- Trial name
- DIEP-MDS (NCT07761390)
- Where
- 20 sites in China
- Volunteers
- 1,500 people
- Sponsor
- Zhuliling
Breast Cancer, Wound Dehiscence, Surgical
ciNPT in Autologous DIEP Flap Breast Reconstruction
In women who undergo mastectomy for the treatment of breast cancer, autologous reconstruction using the deep inferior epigastric perforator (DIEP) flap is a common surgical procedure that aims to restore both the appearance and…
- Trial name
- NCT05907941
- Testing
- ciNPT, Conventional Tape Dressings, DIEP Breast Reconstruction
- Volunteers
- 114 people
- Sponsor
- McMaster University
Breast Reconstruction, Abdominal Wall Morbidity
Changes To The Abdominal Wall After DIEP Flap Breast Reconstruction
The purpose of this study was to perform an evaluation of the structural changes in the abdominal wall after harvesting a DIEP flap in breast reconstruction.
- Trial name
- NCT02563977
- Testing
- 2 year postop CT scan of the abdomen
- Where
- Norway
- Volunteers
- 14 people
- Sponsor
- Oslo University Hospital
Breast Reconstruction
Pre-Operative Imaging of Abdominal Wall Perforators Using CT Angiography
Abdominal donor-site flaps, including the transverse rectus abdominis musculocutaneous (TRAM) and deep inferior epigastric artery perforator flaps(DIEP), are standard in autologous breast reconstruction.
- Trial name
- DIEP (NCT00748722)
- Testing
- CT Angiography
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Breast Cancer, Breast Reconstruction
Sensory Restoration After DIEP Flap Neurotization
Common goals of breast reconstruction include obtaining satisfactory breast symmetry, softness, and appropriate size and shape. Advances in surgical techniques have prompted a new goal: achieving breast sensation after…
- Conditions
- Breast Cancer, Breast Reconstruction, Sensory Restoration
- Trial name
- NCT04533373
- Testing
- DIEP Flap Neurotization
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Johns Hopkins University
Breast Neoplasms, Mammaplasty
ARTISS a Single-centre Randomised Control Study
The Influence of ARTISS on post-operative abdominal drainage and seroma formation in DIEP/MS-TRAM free flap breast reconstruction patients.
- Trial name
- ARTISS (NCT04931615)
- Testing
- ARTISS 4mL Fibrin Sealant Topical Solution (Frozen), no ARTISS
- Where
- United Kingdom
- Volunteers
- 135 people
- Sponsor
- Mid and South Essex NHS Foundation Trust
Breast/Surgery
Nipple-sparing Mastectomy in Combined With Buried Flap Monitoring
1. Learning curve of ms-Tram and DIEP breast reconstructions surgery are important to guide the training of new surgeon. 2. Buried flap post operative monitoring without implantable doppler was seldom studied, a validated…
- Trial name
- NCT05560633
- Testing
- No intervention
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Deep Inferior Epigastric Perforator Flap Breast Reconstruction
TAP vs QL Block for DIEP Flap Breast Reconstruction
The purpose of this two-arm clinical study is to compare two nerve block techniques, the transversus abdominis plane (TAP) block and the quadratus lumborum (QL) block, in terms of how well they manage pain in the immediate…
- Trial name
- NCT06962150
- Testing
- Surgeon-placed transversus abdominis plane block, Ultrasound-guided quadratus lumborum block
- Sponsor
- Yale University
Breast Cancer, Breast Reconstruction
Incorporating Robotic Surgery in Both Mastectomy and DIEP Flap Reconstruction
A prospective study will be conducted to assess the outcomes of patients who underwent concurrent robotic-assisted mastectomy and robotic-assisted free DIEP flap harvest for breast reconstruction between March 2020 and June 25…
- Trial name
- NCT05945914
- Testing
- Oncoplastic Entirely Robot-Assisted Approach (OPERA)
- Where
- Taiwan
- Volunteers
- 9 people
- Sponsor
- Chang Gung Memorial Hospital
Breast Reconstruction
Pain Study Using Intermittent Bupivacain Injections After Breast Reconstruction With DIEP Flap
patients are given bupivacain intermittent locally on the donor site after brest reconstruction with diep flap. The hypothesis was that this approach will reduce the need for rescue analgetic medication and pain perception within…
- Trial name
- NCT00804674
- Testing
- bupivacain
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Ullevaal University Hospital
Perioperative Tissue Oxygenation
Improving Tissue Oxygenation in Breast Reconstruction Surgery
Breast reconstruction is an integral part of breast cancer care. There are two main types of breast reconstruction: alloplastic (using implants), and autologous (using patient's tissue).
- Trial name
- NCT04020172
- Testing
- Dobutamine
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Dr. Glenio Mizubuti (MD, PhD)
Breast Reconstruction, Deep Inferior Epigastric Perforator
The Effects of Caffeine on Deep Inferior Epigastric Perforator (DIEP) Flap Perfusion
Women that require breast reconstruction and meet eligibility will be enrolled in this study. The study is being completed to determine the effect of caffeine in deep inferior epigastric perforator (DIEP) flap perfusion using the…
- Conditions
- Breast Reconstruction, Deep Inferior Epigastric Perforator, Microvascular Free Flap Transfer
- Trial name
- NCT04249934
- Testing
- Caffeinated Coffee, DecaffeinatedCoffee
- Where
- United States
- Sponsor
- University of Michigan
Breast Cancer, Perforator Flap
Deep Inferior Epigastric Artery Flap for Breast Reconstruction
Background: There is no consensus on the duration of prophylactic antibiotics for autologous breast reconstruction after mastectomy.
- Conditions
- Breast Cancer, Perforator Flap, Anti-Infectives Adverse Reaction, Infections
- Trial name
- NCT05088239
- Testing
- prophylactic antibiotics duration
- Volunteers
- 108 people
- Sponsor
- Chiayi Christian Hospital
Reconstructive Surgical Procedures
DIEP Flap Perfusion Evaluated by DIRT and ICG-FA.
Patients selected for DIEP breast reconstruction were examined with preoperative CTA, Doppler Ultrasound, dynamic infrared thermography (DIRT) and Indocyanin green fluorescent angiography (ICG-FA) for perforator mapping.
- Trial name
- NCT04115995
- Testing
- Dynamic infrared thermography (DIRT) and indocyanine green fluorescence angiography (ICG-FA)
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Hypotension During Surgery
Goal-directed Fluid Therapy During Deep Inferior Epigastric Perforator (DIEP) Free Flap Breast Reconstruction
Adequate free flap perfusion during Deep Inferior Epigastric Perforator (DIEP) flap breast reconstruction surgery requires maintaining blood pressure above 100 mmHg and avoiding excessive fluid administration.
- Trial name
- GDFT DIEP-flap (NCT06080178)
- Testing
- Plasma-lyte (static group), Norepinephrine (static group), Plasma-lyte (dynamic group)
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Breast Cancer
Intraoperative Pathway in DIEP Flap Breast Reconstruction
Efficiency in the operating room can be difficult in long cases with multiple surgeons. We used a team based approach to develop an intraoperative pathway for microsurgical breast reconstruction with a deep inferior epigastric…
- Trial name
- NCT00543764
- Testing
- pathway
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Breast Cancer
BENEFIT OF MECHANICAL ISCHEMIC PRECONDITIONING ON TOLERANCE OF ADIPOSE TISSUE TO ISCHEMIA REPERFUSION OF TYPE DIEP (DEEP INFERIOR EPIGASTRIC PERFORATOR) FREE FLAPS.
Breast cancer is the most common cancer amongst women in terms of frequency, with more than 50 000 newly diagnosed cases per year in France. The average 5-year survival rate for women with breast cancer is around 85%.
- Trial name
- PRIMIDIEP (NCT05373069)
- Testing
- Mechanical ischemic preconditioning of diep-type flap
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breast Cancer
Outcomes of a Deep Inferior Epigastric Perforator Flap Program
The purpose of this study is to analyze an institution's experience with starting a subspecialized DIEP flap program.
- Trial name
- NCT00543907
- Where
- United States
- Volunteers
- 977 people
- Sponsor
- Beth Israel Deaconess Medical Center
Breast Cancer
Preoperative Imaging in DIEP Flap Breast Reconstruction
The purpose of this study is to determine whether preoperative abdominal imaging using either CT angiogram (CTA), or MR angiogram (MRA) will impact perforator dissection time, cost, and patient outcomes in DIEP flap breast…
- Trial name
- NCT02111239
- Testing
- CTA, MRA
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Sensitisation
DIEP (Deep Inferior Epigastric Artery Perforator) Flap Sensory Recovery Following Neurotization
The purpose of this study is to compare the sensory return of DIEP flaps with nerve connection to DIEP flaps with no nerve connection to see which is better.
- Trial name
- NCT04818190
- Testing
- Sensory neurotization
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba