Clinical trials: DIEP Flap Breast Reconstruction
Breast Cancer, Wound Dehiscence, Surgical
ciNPT in Autologous DIEP Flap Breast Reconstruction
In women who undergo mastectomy for the treatment of breast cancer, autologous reconstruction using the deep inferior epigastric perforator (DIEP) flap is a common surgical procedure that aims to restore both the appearance and…
- Trial name
- NCT05907941
- Testing
- ciNPT, Conventional Tape Dressings, DIEP Breast Reconstruction
- Volunteers
- 114 people
- Sponsor
- McMaster University
Breast Reconstruction, Breast Cancer
Comparison of PEAK PlasmaBlade™ to Conventional Diathermy in Abdominal Based Free Flap Breast Reconstruction
Electrosurgery allows for dissection with simultaneous haemostasis. One of its disadvantages is that the heat production can cause injury to the surrounding tissue which may result in wound healing problems and an increased rate…
- Trial name
- NCT04350411
- Testing
- Conventional diathermy, PEAK PlasmaBlade™
- Where
- United Kingdom
- Volunteers
- 108 people
- Sponsor
- Anglia Ruskin University
Breast Cancer Surgery, Reconstruction Breast Surgery
Improvement in Breast Skin Sensibility After Breast Reconstruction: a Comparison of 3 Surgical Techniques
The goal of this clinical trial is to learn if nerve sutures in free flap breast reconstruction can optimize sensibility in the reconstructed breast in patients opting for DIEP flap breast reconstruction due to breast cancer or…
- Conditions
- Breast Cancer Surgery, Reconstruction Breast Surgery, Sensitization, DIEP Flap Breast Reconstruction
- Trial name
- S-DIEP (NCT06930378)
- Testing
- Nerve Suture
- Where
- Switzerland
- Volunteers
- 63 people
- Sponsor
- Patricia Esther Engels
Breast Cancer, Mastectomy; Lymphedema
OPERA - Incorporating Robotic Surgery in Both Mastectomy and DIEP Flap Reconstruction
Current breast cancer surgery is achieving minimally invasive approach to reduce incision while providing better surgical vision and freedom in mastectomy.
- Trial name
- NCT06415526
- Testing
- OPERA
- Where
- Taiwan
- Volunteers
- 14 people
- Sponsor
- Chang Gung Memorial Hospital
Post-operative Pain, DIEP Flap Breast Reconstruction
Suzetrigine Post DIEP
This research study is being conducted to see whether adding suzetrigine (Journavx), an FDA-approved non-opioid pain medication, to the standard Enhanced Recovery After Surgery (ERAS) pain management protocol can improve pain…
- Conditions
- Post-operative Pain, DIEP Flap Breast Reconstruction, DIEP Flap, Opioid
- Trial name
- NCT07839715
- Testing
- Suzetrigine Group
- Volunteers
- 198 people
- Sponsor
- Vanderbilt University Medical Center
Deep Inferior Epigastric Perforator Flap Breast Reconstruction
TAP vs QL Block for DIEP Flap Breast Reconstruction
The purpose of this two-arm clinical study is to compare two nerve block techniques, the transversus abdominis plane (TAP) block and the quadratus lumborum (QL) block, in terms of how well they manage pain in the immediate…
- Trial name
- NCT06962150
- Testing
- Surgeon-placed transversus abdominis plane block, Ultrasound-guided quadratus lumborum block
- Sponsor
- Yale University
Breast Reconstruction, Deep Inferior Epigastric Perforator
The Effects of Caffeine on Deep Inferior Epigastric Perforator (DIEP) Flap Perfusion
Women that require breast reconstruction and meet eligibility will be enrolled in this study. The study is being completed to determine the effect of caffeine in deep inferior epigastric perforator (DIEP) flap perfusion using the…
- Conditions
- Breast Reconstruction, Deep Inferior Epigastric Perforator, Microvascular Free Flap Transfer
- Trial name
- NCT04249934
- Testing
- Caffeinated Coffee, DecaffeinatedCoffee
- Where
- United States
- Sponsor
- University of Michigan
Breast Cancer
Influence of the Superficial Inferior Epigastric System in Deep Inferior Epigastric Perforator (DIEP) Flaps
The purpose of this study is to determine in-vivo the effects the contralateral superficial inferior epigastric vascular system has on the perfusion of Zone IV of deep inferior epigastric perforator flaps.
- Trial name
- NCT01464970
- Testing
- Both Superficial Inferior Artery and Vein Clamped, Superficial Inferior Epigastric Vessels both unclamped, SIE Artery Unclamped, Vein Clamped
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- NHS Greater Glasgow and Clyde
Breast Cancer
Intraoperative Pathway in DIEP Flap Breast Reconstruction
Efficiency in the operating room can be difficult in long cases with multiple surgeons. We used a team based approach to develop an intraoperative pathway for microsurgical breast reconstruction with a deep inferior epigastric…
- Trial name
- NCT00543764
- Testing
- pathway
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Breast Reconstruction After Mastectomy
A Comparative Study of Delayed Endoscopic DTI and Autologous Flap Reconstruction Post-Mastectomy
In China, low breast-conserving surgery rates and historically minimal immediate reconstruction following mastectomy have resulted in a significant population of women living without a breast, often leading to long-term…
- Trial name
- DEDIA (NCT07602868)
- Volunteers
- 263 people
- Sponsor
- West China Hospital
Breast Reconstruction, Mastectomy; Lymphedema
New Era of DIEP With Minimally Invasive Mastectomy
The free deep inferior epigastric artery perforator (DIEP) flap is the gold standard in autologous breast reconstruction. Asian patients often present with a smaller body mass index with relatively insufficient tissue.
- Trial name
- NCT06321549
- Testing
- The reference point of minimally invasive mastectomy procedure conducted
- Where
- Taiwan
- Volunteers
- 278 people
- Sponsor
- Chang Gung Memorial Hospital
Breast Cancer
Nerve Coaptation in DIEP Flap Breast Reconstruction
The sensory recovery of the breast remains an undervalued aspect of breast reconstruction and surgical reinnervation is not regarded as a priority by most reconstructive surgeons.
- Trial name
- NCT03428789
- Testing
- Sensory nerve coaptation
- Where
- Netherlands
- Volunteers
- 81 people
- Sponsor
- Maastricht University Medical Center
Breast Reconstruction
Pain Study Using Intermittent Bupivacain Injections After Breast Reconstruction With DIEP Flap
patients are given bupivacain intermittent locally on the donor site after brest reconstruction with diep flap. The hypothesis was that this approach will reduce the need for rescue analgetic medication and pain perception within…
- Trial name
- NCT00804674
- Testing
- bupivacain
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Ullevaal University Hospital