Clinical trials: DMPA
Contraceptive Behavior, Self Administration
Impact of Self-Care Family Planning Services on Health and Development in South Sudan (Family Planning Impact Lab)
Since 2019, the International Rescue Committee (IRC) has led family planning programming under the Women's Integrated Sexual Health (WISH) program, funded by the United Kingdom's Foreign, Commonwealth, and Development Office.
- Trial name
- FPIL (NCT07888296)
- Testing
- Self-Managed Contraceptive Care, Standard Family Planning Services (WISH-2)
- Where
- South Sudan
- Volunteers
- 2,736 people, healthy volunteers welcome
- Sponsor
- Guttmacher Institute
Grade 1 Endometrial Endometrioid Adenocarcinoma, Grade 2 Endometrial Endometrioid Adenocarcinoma
The Effect of Neoadjuvant DMPA on Glandular Cellularity in Women Awaiting Hysterectomy
Objective: To compare pre- and post-treatment glandular cellularity in women with complex atypical hyperplasia or grade 1-2 endometrial adenocarcinoma who are treated with intramuscular depot medroxyprogesterone acetate (DMPA)…
- Conditions
- Grade 1 Endometrial Endometrioid Adenocarcinoma, Grade 2 Endometrial Endometrioid Adenocarcinoma, Complex Atypical Endometrial Hyperplasia
- Trial name
- NCT02335203
- Testing
- Depot medroxyprogesterone acetate
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Abnormal Uterine Bleeding, Tranexamic Acid
Comparative Study of Tranexamic Acid, Estrogen for Treatment AUB in DMPA Users
Abnormal uterine bleeding is the most common problems to discontinue Depo-medroxyprogesterone acetate (DMPA) in Thailand. This clinical trial use to provide drug to stop abnormal uterine bleeding from DMPA
- Conditions
- Abnormal Uterine Bleeding, Tranexamic Acid, Estrogen, Depot Medroxyprogesterone Acetate
- Trial name
- NCT06067217
- Testing
- Tranexamic acid 250 mg oral tablet, Progynova 1 mg oral tablet
- Where
- 2 sites in Thailand
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
HIV Infections
Prospective Cohort Evaluating Pregnancy Rates, PK Interactions Among HIV+ Women on EFV Initiating LNG Implant or DMPA
The purpose of this study is to compare the pregnancy rates among women who are using the HIV drug Efavirenz and either the birth control injection or implant.
- Trial name
- FP-ART (NCT03153709)
- Where
- Malawi
- Volunteers
- 1,382 people
- Sponsor
- University of North Carolina, Chapel Hill
Uterine Hemorrhage
Doxycycline in Treatment of Bleeding With Depot Medroxyprogesterone Acetate (DMPA)
This study aims to test the effect of Doxycycline in treatment of uterine bleeding during the use of injectable contraception that contains one hormone "progesterone only".
- Trial name
- DOX-DMPA (NCT01254799)
- Testing
- Doxycycline
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Omar Mamdouh Shaaban
Postpartum Contraception, Depot Medroxyprogesterone Acetate
Measuring Lactation Initiation After Early Postpartum Injectable Progestin (DMPA) Use Among Women in Dhanusha District of Nepal: A Pilot Study
This is a pilot study of early postpartum initiation of the injectable progestin contraception, depo medroxyprogesterone acetate (DMPA), among 40 postpartum people.
- Conditions
- Postpartum Contraception, Depot Medroxyprogesterone Acetate, Lactation, DMPA
- Trial name
- NCT06816901
- Testing
- Depo Medroxyprogesterone acetate
- Where
- Nepal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Contraception, Family Planning
Community Based Distribution of Injectable Contraceptives in Tigray, Ethiopia
The purpose of this study was to demonstrate that with appropriate training, the provision of injectable contraceptives by community based reproductive health agents (CBRHAs) does not significantly differ from low-level…
- Conditions
- Contraception, Family Planning, Task Shifting, Community Based Distribution
- Trial name
- CBDDMPA (NCT01288274)
- Testing
- Community Based administration of DMPA
- Where
- 3 sites in Ethiopia
- Volunteers
- 1,062 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Contraception, HIV
HIV-Target Cell Response in Women Initiating Various Contraceptive Methods in High HIV-Incidence Areas: Zim CHIC
This study is being done to understand if using birth control causes changes in the immune cells within the reproductive tract of healthy women.
- Conditions
- Contraception, HIV, Immune Cells (Mucosal and Systemic), Microbiota
- Trial name
- Zim CHIC (NCT02038335)
- Testing
- DMPA, NET-EN, MPA/E2
- Where
- Zimbabwe
- Volunteers
- 451 people
- Sponsor
- University of Pittsburgh
Contraception
Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone (HOP 5) Testicular Aspiration Addendum
This study is being offered to all participants of the ACY-5 study as an optional addition to the male contraceptive study in which they participated. Participation is voluntary.
- Trial name
- IHOP-5 (NCT00156650)
- Testing
- Acyline, Testosterone Gel, Depo-Medroxyprogesterone
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Washington
Human Immunodeficiency Virus, Contraception
Investigating the Interaction Between Two Long-acting Reversible Methods of Contraception and Dolutegravir, a Treatment for HIV
It is important to make sure that women have access to effective methods of contraception to prevent pregnancy so that they can make choices about when and if they will have their first or next child.
- Conditions
- Human Immunodeficiency Virus, Contraception, ART
- Trial name
- CODA (NCT04910711)
- Testing
- Dolutegravir, Levonorgestrel implant, Depo medroxyprogesterone acetate injection
- Where
- Botswana
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Botswana Harvard AIDS Institute Partnership
Contraception
Clinical Study of Depo Provera Comparing Lay Health Workers and Clinically-trained Health Workers
This is a randomized controlled trial comparing lay Lady Health Workers (Lay Health Workers) with Family Welfare Workers (Clinically- trained Health Workers) on quantitative measures of safety and effectiveness of Depo Provera…
- Trial name
- NCT03255941
- Testing
- DMPA, Sayana Press
- Where
- Pakistan
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- FHI 360
Contraception
Male Hormonal Contraceptive Development-ACY-5
The purpose of this research study is to help in the development of male contraception (birth control).
- Trial name
- ACY-5 (NCT00161447)
- Testing
- Acyline, Testosterone Gel, Depo-Medroxyprogesterone
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Washington
Endometriosis
Effectiveness of Levonorgestrel-intrauterine System (LNG-IUS) Versus Depot Medroxyprogesterone Acetate (DMPA) in Treatment of Pelvic Pain in Clinically Diagnosed Endometriotic Patients
randomized controlled trial Eligiblility criteria Provisional diagnosis Clinical presentation Progressive dysmenorrhea Chronic pelvic pain Deep dyspareunia Evidences of endometriosis Endometriotic nodule Cul-de-sac nodularity…
- Trial name
- NCT02534688
- Testing
- LNG-IUS, DMPA
- Where
- Thailand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King Chulalongkorn Memorial Hospital
Clinically Diagnosed Endometriotic Patient Was Defined as a Woman Who Has Pelvic Pain and at Least One Evidence of PV or TVS
Effectiveness of Levonorgestrel-intrauterine System (LNG-IUS) Versus Depot Medroxyprogesterone Acetate (DMPA) in Treatment of Pelvic Pain in Clinically Diagnosed Endometriotic Patients
The primary objective : To compare effectiveness of pain control in endometriosis associated pelvic pain between LNG-IUS and DMPA The secondary objective : To compare vaginal bleeding pattern, side effect, continuation rate…
- Trial name
- NCT02894151
- Testing
- Depot medroxyprogesterone acetate, LNG-IUS
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Dysfunctional Uterine Bleeding
DMPA & High Dose Oral Progestin (MPA) Tablets in Outpatient Treatment of Acute Excessive Vaginal Bleeding
The purpose of this study is to investigate the effectiveness and acceptability of high dose MPA (20mg oral 3 times a day) for 3 days combined with an injection of DMPA 150 mg intramuscularly in the treatment of acute heavy…
- Trial name
- NCT01148420
- Testing
- Medroxyprogesterone 17-Acetate, medroxyprogesterone acetate
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Women's Health Care Clinic, Torrance, California
Weight Change
Weight Change Among Users of Three Progestin-Only Methods of Contraception Over a 12-Month Time Period
The purpose of this study is to learn whether women who use progestin-only methods of birth control such as the contraceptive implant (Implanon), the levonorgestral-releasing IUS (Mirena), or depot medroxyprogesterone…
- Trial name
- BMI (NCT01592058)
- Where
- United States
- Volunteers
- 427 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
HIV Infections
Depo-Medroxyprogesterone Acetate (DMPA, Depo-Provera) Use With Certain Anti-HIV Drugs in HIV-Infected Women
The purpose of this study is to look at the level of depo-medroxyprogesterone acetate (DMPA or Depo-Provera) in the blood to see if is affected by certain anti-HIV drugs (nelfinavir [NFV], efavirenz [EFV], indinavir [IDV] in…
- Trial name
- NCT00016601
- Testing
- Indinavir sulfate, Ritonavir, Nelfinavir mesylate
- Where
- 32 sites in United States, Puerto Rico
- Volunteers
- 76 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)