Clinical trials: DR
Healthy
Bioequivalence Study of Terbinafine Hydrochloride Tablets, 250 mg of Dr. Reddy's Under Fed Conditions
The purpose of this study is to compare the rate and extent of absorption of terbinafine hydrochloride 250 mg tablets versus Lamisil® 250 mg tablets administered as 1 x 250 mg tablet under fed conditions.
- Trial name
- NCT01286701
- Testing
- Terbinafine Hydrochloride Tablets, 250 mg
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Drug Resistant Tuberculosis, MDR-TB
Triage Test for All Oral DR-TB Regimen (TRiAD Study)
A Phase 4 operational study to assess the effectiveness, feasibility, acceptability, and cost effectiveness of the GeneXpert MTB/XDR (Xpert XDR; Cepheid) assay for rapid triage-and-treatment of DR-TB-A multi-centre, multi-country…
- Conditions
- Drug Resistant Tuberculosis, MDR-TB, XDR-TB, Tuberculosis
- Trial name
- NCT05175794
- Testing
- Xpert® MTB/XDR
- Where
- 4 sites in Ethiopia, Nigeria and 1 more
- Volunteers
- 786 people
- Sponsor
- Centre for the AIDS Programme of Research in South Africa
Healthy
A Study Investigating the Effectiveness of a LifeSeasons NeuroQ Supplement With Lifestyle Changes to Improve Cognitive Function in Healthy Adults Who Have One or More Risk Factors for Cognitive Decline
The objective of this study is to evaluate the efficacy of a NeuroQ supplement designed by Dr. Bredesen to complement his Lifestyle modification protocol.
- Trial name
- NCT04149639
- Testing
- NeuroQ
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- LifeSeasons Inc.
Cirrhosis, Acute Hepatitis
Development of a Predictive Score for the Risk of Infection in the Immediate Post-liver-transplant Period
Liver transplantation (LT) is the only curative treatment option for patients with severe liver disease. Since 2007, the implementation of the MELD score in liver transplant allocation guidelines has led to a change in the…
- Conditions
- Cirrhosis, Acute Hepatitis, Liver, mHLA-DR
- Trial name
- PREDITH (NCT07647978)
- Testing
- blood sampling, Biocollection
- Where
- 3 sites in France
- Volunteers
- 279 people
- Sponsor
- Hospices Civils de Lyon
Absent End-Diastolic Flow Of The Fetal Umbilical Artery
Clinical Significance Of Intermittently Absent End-Diastolic Flow Of The Fetal Umbilical Artery On Perinatal And Neonatal Outcomes Dr. Zeynep Kayaoğlu Yıldırım Dr. Alperen İnce Dr Gökhan Bayanmelek Dr Gökhan Bolluk
Objective: This study aimed to estimate the risk of adverse perinatal outcomes among pregnant patients with intermittently absent (iAEDF) and persistently absent end-diastolic umbilical artery flow (pAEDF).
- Trial name
- NCT06346327
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Hypertensive Heart Disease
Hypertensive Heart Disease in DR Congo
In this Cross-sectional study, we will analyzed data from a tertiary referral Congolese hospital to find whether or not Congolese patients with hypertensive heart disease have multiple comorbid conditions.
- Trial name
- NCT06524440
- Where
- Democratic Republic of the Congo
- Volunteers
- 400 people
- Sponsor
- Association of Future African Neurosurgeons, Yaounde, Cameroon
Tachyarrhythmia
Study to Verify Proper Detection of Supraventricular Tachyarrhythmia With Single-Lead Dual-Chamber Implantable Cardioverter-Defibrillators (ADRIA)
A unique single-lead dual-chamber implantable cardioverter-defibrillator (ICD) system (produced by Biotronik, Germany) features a conventional electrode in the ventricle (anchored in the ventricular apex) and a floating electrode…
- Trial name
- NCT00324662
- Testing
- Implantable cardioverter-defibrillator
- Where
- 10 sites in Germany, Switzerland
- Volunteers
- 260 people
- Sponsor
- Biotronik SE & Co. KG
Sepsis, Macrophage Activation Syndrome
A Trial of Validation and Restoration of Immune Dysfunction in Severe Infections and Sepsis
The aim of the study is to conduct one RCT of personalized immunotherapy in sepsis targeting patients who lie either on the predominantly hyper-inflammatory arm or on the predominantly hypo-inflammatory arm of the spectrum of the…
- Trial name
- PROVIDE (NCT03332225)
- Testing
- Anakinra, Recombinant human interferon-gamma
- Where
- 13 sites in Greece
- Volunteers
- 36 people
- Sponsor
- Hellenic Institute for the Study of Sepsis
Persistent Asthma
Effect of Vitamin D Supplementation on the Control of Asthma in Children at a South African Academic Hospital
The aim of this randomized double-blind placebo controlled study is to assess whether vitamin D supplementation will improve control in South African children with persistent asthma at an academic hospital.
- Trial name
- NCT02053402
- Testing
- Vitamin D
- Where
- South Africa
- Volunteers
- 100 people
- Sponsor
- University of Limpopo
Diabetes Mellitus, Diabetic Retinopathy (DR)
Improving Patient-centered Care for Diabetes in Bangladesh Through "Dynamic Integration" of Vision Care on the Demand Side
The goal of this clinical trial is to determine whether there is an increase in participant uptake of diabetes mellitus (DM) and diabetic retinopathy (DR) services and improved quality of patient-centered diabetic care resulting…
- Trial name
- NCT06968611
- Testing
- Education/information of risk, Free eye glasses
- Where
- 2 sites in Bangladesh
- Volunteers
- 640 people
- Sponsor
- Orbis
Sudden Cardiac Death
Ovatio DR and VR Implantable Cardioverter Defibrillators Post-approval Study
The purpose of this post-approval study is to confirm the safety and effectiveness of Ovatio DR and VR ICDs
- Trial name
- Post-Ovatio (NCT00586378)
- Testing
- Ovatio DR and Ovatio VR
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- ELA Medical, Inc.
Fasting
Bioequivalence Study of Olanzapine Tablets, 5 mg of Dr. Reddy's Under Fasting Conditions
The purpose of this study is to compare the bioequivalence and characterize the profile of the olanzapine tablets, 5 mg with zyprexa tablets, 5 mg in healthy, adult, human subjects under fasting conditions and to monitor the…
- Trial name
- NCT01503398
- Testing
- Olanzapine
- Where
- India
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Dry AMD, Diabetic Retinopathy (DR)
Microperimetry Changes in Retinal Function in Macular Disorders
The purpose of this study is to measure precisely how sensitive the central part of the retina - the light-sensitive film at the back of the eye, is to light.
- Trial name
- MAIAStud (NCT07170683)
- Testing
- MAIA Microperimetry, Microperimetry, Visual Acuity Measurement (logMAR)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Malaria in Pregnancy
Comparison of ISTp- PYRAMAX-US-RDT to IPTp-SP to Prevent Malaria in Pregnant Women in DRC (ULTRAPYRAPREG)
In endemic settings Plasmodium falciparum (Pf) can sequester in the placenta resulting in low peripheral parasitemia and false negative malaria diagnosis in pregnant women.
- Trial name
- ULTRAPYRAPREG (NCT04783051)
- Testing
- Sulfadoxine pyrimethamine, Pyramax
- Where
- Democratic Republic of the Congo
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Kinshasa
Diabetic Retinopathy (DR), Retinal Microvascular Changes
Relation Between Glycemic Control and Retinal Microvascular Changes in Diabetic Patients Using OCTA
An observational cross-sectional comparative study which will be conducted in the Department of Ophthalmology, Sohag University Hospital, Egypt to detect the relation between glycemic control and retinal microvascular changes in…
- Trial name
- Retinopathy (NCT07726381)
- Volunteers
- 50 people
- Sponsor
- Sohag University
Tension-Type Headache
The Effectiveness of Auricular Point Compared to Body Point Acupuncture Theraphy on Tension-Type Headache
The purpose of this study is to compare the effectiveness of manual acupuncture between 2 types of points in decreasing tension-type headache symptoms of healthcare workers in Dr.Cipto Mangunkusumo hospital
- Trial name
- NCT05254028
- Testing
- filiform needle
- Where
- Indonesia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
HIV/AIDS, Antiretroviral Therapy
Long Term Outcomes of Therapy in Women Initiated on Lifelong ART Because of Pregnancy in DR Congo
Despite the rapid adoption of the World Health Organization's 2013 guidelines, many children continue to be infected with HIV perinatally because of sub-optimal adherence to the continuum of HIV care in maternal and child health…
- Conditions
- HIV/AIDS, Antiretroviral Therapy, Pregnancy Outcomes, HIV-exposed Infants
- Trial name
- CQI-PMTCT (NCT03048669)
- Testing
- Continuous quality improvement
- Where
- Democratic Republic of the Congo
- Volunteers
- 5,053 people
- Sponsor
- Albert Einstein College of Medicine
Liver Graft Dysfunction
Delayed CNI-based Immunosuppression With Advagraf After MELD-based Liver Transplantation
Prolonged-release low-dose Advagraf should better protect from CNI-side effects compared to standard immunosuppressive regiments while the rate of rejection is not increased and thus graft function is well maintained.
- Trial name
- IMUTECT (NCT01781195)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Heidelberg University
Diabetic Retinopathy
Using Calcium Dobesilate to Treat Chinese Patients With Mild to Moderate Non-proliferative Diabetic Retinopathy
Calcium dobesilate has been recommended to treat diabetic retinopathy due to its potential in protecting against retinal vascular damage.
- Trial name
- CALM-DR (NCT04283162)
- Testing
- Calcium Dobesilate, conventional treatment
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Zhongda Hospital
Ventilator Weaning, Mechanical Ventilation
Comparison of Diaphragm Ultrasound and RSBI for Predicting Weaning Success in Mechanically Ventilated ICU Patients
The goal of this observational study is to evaluate the predictive value of diaphragmatic ultrasound compared to the Rapid Shallow Breathing Index (RSBI) in determining weaning success among mechanically ventilated patients in…
- Conditions
- Ventilator Weaning, Mechanical Ventilation, Respiratory Insufficiency Requiring Mechanical Ventilation, Weaning From Mechanical Ventilation
- Trial name
- NCT07120438
- Volunteers
- 55 people
- Sponsor
- Gadjah Mada University