Clinical trials: DWI
Cannabis
Detection of Cannabis Impairment With ISBRG's SpotLight-THC
Subjects will participate in a 2-visit study protocol in which they will be administered cannabis of pre-determined concentrations and asked to complete a simulated drive in a driving simulator.
- Trial name
- NCT05276232
- Testing
- Cannabis(THC) inhaled
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- ISBRG Corp
Brain Tumor, Glioblastoma
Measuring Non-Enhancing Glioblastoma Progression
The goal of this clinical research study is to learn if magnetic resonance imaging with magnetic resonance spectroscopy ("MRI/MRS" scanning) can measure any extra growth in the tumor that does not show up on regular MRI images.
- Trial name
- NCT00777686
- Testing
- MRI/MRS Scan
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- M.D. Anderson Cancer Center
Prostate Cancer, Bladder Cancer
USPIO-enhanced and Diffusion-weighted MRI for the Detection of Pelvic Lymph Node Metastases
Preoperative detection of lymph node metastases in patients with prostate or bladder cancer is crucial for selection of the appropriate treatment strategy (surgery, androgen deprivation with/or without radiation therapy or…
- Trial name
- NCT00622973
- Testing
- Imaging: diffusion-weighted MRI, Sinerem (USPIO) enhanced MRI
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Glioblastoma (GBM)
Advanced Diffusion MRI to Differentiate Tumor Recurrence From Pseudoprogression in Patients With Glioblastoma and Brain Metastases
This pilot study investigates whether advanced diffusion-weighted MRI (ADW-MRI) can differentiate between true tumor progression (TP) and a pseudoprogression (PsP) in patients with glioblastoma (GBM) or brain metastases.
- Trial name
- AiD-GLIO (NCT05911230)
- Testing
- Advanced diffusion-weighted MRI (ADW-MRI)
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- University Hospital, Basel, Switzerland
Esophageal Carcinoma
Diffusion-weighted Magnetic Resonance Imaging (DW-MRI )for Early Response Assessment in Patients With Esophageal Cancer
Esophageal carcinoma is a lethal disease, causing more than 400,000 deaths annually worldwide. Primary surgery results in microscopically positive resection margins (R1) in 25% patients, and the 5-year overall survival(OS) for…
- Trial name
- NCT02527057
- Testing
- DW-MRI
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Hunan Province Tumor Hospital
Melanoma
Whole-body DW-MRI and cfDNA Analysis for the Surveillance of Melanoma Patients at High Risk for Recurrence.
Patients with locally advanced melanoma are at high risk for recurrence following surgical treatment. More patients with stage IV melanoma remain in complete remission following systemic therapy.
- Trial name
- DW-MRi (NCT02907827)
- Testing
- follow up DW MRI
- Where
- 2 sites in Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Ovarian Carcinoma, Ovarian Cancer
Study Into a New Diagnostic Tool (Simple Ultrasound-based Rules) in Patients With Adnexal Masses
This study is performed to compare the diagnostic performance and cost-effectiveness of different diagnostic methods for differentiating benign from malignant adnexal (ovary or Fallopian tube) masses: the Risk of Malignancy Index…
- Conditions
- Ovarian Carcinoma, Ovarian Cancer, Ovarian Mass, Ovarian Cyst
- Trial name
- SUBSONiC (NCT02218502)
- Testing
- Ultrasound by general gynaecologist, Ultrasound by an expert ultrasonographist, DW-MRI
- Where
- 5 sites in Netherlands
- Volunteers
- 50 people
- Sponsor
- Maastricht University Medical Center
Ewing Sarcoma, Osteosarcoma
Osteosarcoma and Ewing Sarcoma Treatment Response Assessment With Functional MRI Imaging in Children and Young Adults
The purpose of the study was to investigate whether functional MRI imaging (diffusion weighted imaging) is useful for monitoring the therapeutic response of bone sarcomas in children and young adults.
- Trial name
- FUBEO (NCT01780779)
- Testing
- MRI
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Head and Neck Squamous Cell Carcinoma
Predictive Value of Diffusion-weighted MRI Performed in Early Post-treatment in the Occurrence of Tumor Recurrence or Progression in Head and Neck Squamous Cell Carcinoma Treated With Chemoradiotherapy: a Pilot Study
Head and neck squamous cell carcinoma are frequent. The chemoradiotherapy protocols are part of the reference treatment of locally advanced stage tumors.
- Trial name
- ORODIFF (NCT02862678)
- Testing
- diffusion-weighted MRI
- Where
- France
- Volunteers
- 59 people
- Sponsor
- CHU de Reims
Head and Neck Cancer, Thyroid Cancer
New MRI Biomarkers in Head and Neck Cancers
Magnetic resonance imaging (MRI) is a diagnostic technique that takes pictures of organs of the body. It uses magnetic fields and radio waves that cannot be felt.
- Trial name
- NCT03483337
- Testing
- MRI examinations
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Heart Attack
Efficacy of Non Contrast DWI(Diffusion Weighted Imaging) Imaging Compared to DMR-DE
Use of MRI and DWI to diagnose cardiac scarring after heart attack.
- Trial name
- NCT01820000
- Testing
- Diffusion Weighted Imaging with MRI scans
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Fetal Growth Restriction (FGR)
DIFFUSION WEIGHTED MRI FINDINGS IN FETUSES WITH AND WITHOUT FETAL GROWTH RESTRICTION
This prospective observational study aims to compare fetal brain diffusion-weighted magnetic resonance imaging (DWI) findings in fetuses with and without fetal growth restriction (FGR) and to evaluate the association between…
- Trial name
- NCT07769957
- Testing
- Diffusion-weighted fetal brain MRI
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Stroke, TIA
The Effect Of Remote Limb Ischemic Preconditioning For Carotid Artery Stenting
Remote limb ischemic preconditioning is neuro-protective and anti-inflammatory for ischemia- reperfusion injury. As the extent of its effect is unknown, the investigators will use clinical outcome, serum biochemical markers and…
- Conditions
- Stroke, TIA, Coronary Stenosis
- Trial name
- NCT01175876
- Testing
- remote limb ischemic preconditioning, Carotid Artery Stenting
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
Low Grade Glioma, Malignant Glioma
Rotating Frame Relaxation and Diffusion Weighted Imaging of Human Gliomas
Grading of gliomas is of significant clinical importance since the prognosis as well as the treatment of choice are distinct in low-grade and high-grade gliomas.
- Trial name
- RODIG (NCT02186262)
- Where
- Finland
- Volunteers
- 36 people
- Sponsor
- Turku University Hospital
Uterine Fibroid
MR Elastography Parameters Impact on MR-HIFU Efficacy in Uterine Fibroids
Magnetic resonance (MR)-guided high-intensity focused ultrasound (HIFU) ablation for fibroids is an outpatient approach for controlling symptom with an excellent safety record.
- Trial name
- ELASTUS (NCT04345003)
- Testing
- Myoma elastography
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Bordeaux
Ovarian Carcinoma
Whole-body Diffusion MRI for Staging, Response Prediction and Detecting Tumor Recurrence in Patients With Ovarian Cancer
The aim of this study is to assess whole body diffusion weighted imaging (WB-DWI) as a non-invasive method for accurate staging of patient suspected having ovarian cancer early treatment assessment detecting tumor recurrence
- Trial name
- S53580 (NCT01657747)
- Testing
- Whole body diffusion-weighted MRI
- Where
- Belgium
- Volunteers
- 350 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cannabis, Alcohol Effect
Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study II
The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.
- Conditions
- Cannabis, Alcohol Effect, Driving Under the Influence of Alcohol and Other Drugs
- Trial name
- THC-ETOH-II (NCT02710097)
- Testing
- Active inhaled cannabis, Active Oral Ethanol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Drinking, Alcohol Intoxication
WayToServePlus: Improving Responsible Alcohol Service Ph II
Responsible beverage service (RBS) training for alcohol servers is a promising intervention for reducing driving while intoxicated (DWI) by alcohol.
- Conditions
- Alcohol Drinking, Alcohol Intoxication, Alcohol Use, Unspecified
- Trial name
- NCT05779774
- Testing
- WayToServe Plus In-service Component, WayToServe Training Only
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Infant Development
Developing Advanced MRI Methods for Detecting the Impact of Nutrients on Infant Brain Development
The purpose is to study the effect of infant nutrition on brain development, as measured using Magnetic Resonance (MR) techniques.
- Trial name
- NCT02058225
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Active Ethanol and Active Iomazenil, Active Ethanol and Placebo Iomazenil
Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans
Alcohol is abused commonly, but there is no remedy for alcohol intoxication. This project is looking at the substance iomazenil and its effect on alcohol intoxication and alcohol's effects on driving using a driving simulator.
- Conditions
- Active Ethanol and Active Iomazenil, Active Ethanol and Placebo Iomazenil, Placebo Ethanol and Active Iomazenil, Placebo Ethanol and Placebo Iomazenil
- Trial name
- NCT01590277
- Testing
- Active Ethanol, Active Iomazenil
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development